Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage

Free Radical Biology and Medicine

Volumn 52, Issue 5, 2012, Pages 928-936

  Wang, Bing ^a,b   Zhu, Xiaolei ^a   Kim, Yuntai ^b   Li, Jie ^a   Huang, Siyuan ^b   Saleem, Sofiyan ^b   Li, Rung Chi ^b   Xu, Yun ^a   Dore, Sylvain ^c   Cao, Wangsen ^a,b  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cerebral ischemia; HDAC inhibition; Nrf2; TSA

Indexed keywords

GLUCOSE; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; KELCH LIKE ECH ASSOCIATED PROTEIN 1; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; TRICHOSTATIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CATALYSIS; CELL VIABILITY; CONTROLLED STUDY; DISSOCIATION; ENZYME INHIBITION; GENE EXPRESSION; GENE REPRESSION; GENE TRANSLOCATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STROKE; TRANSCRIPTION INITIATION; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CYTOSKELETAL PROTEINS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PROTEIN BINDING; RESPONSE ELEMENTS;

MUS;

EID: 84862824580     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.12.006     Document Type: Article

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