Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: A study of a unique resource in the Gambia

Human Molecular Genetics

Volumn 21, Issue 9, 2012, Pages 2086-2101

  Khulan, Batbayar ^a,f   Cooper, Wendy N ^a   Skinner, Benjamin M ^a   Bauer, Julien ^a   Owens, Stephen ^b,c   Prentice, Andrew M ^b,c   Belteki, Gusztav ^a,d   Constancia, Miguel ^a,e   Dunger, David ^a   Affara, Nabeel A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^d CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^e Cambridge Biomedical Research Centre ^*  (United Kingdom)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PLACEBO; TRACE ELEMENT;

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIET SUPPLEMENTATION; DNA METHYLATION; DOUBLE BLIND PROCEDURE; EPIGENETICS; FEMALE; GAMBIA; HUMAN; INFANT; MALE; MATERNAL NUTRITION; NEWBORN; NUCLEOTIDE SEQUENCE; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; UMBILICAL CORD BLOOD;

ADOLESCENT; ADULT; CPG ISLANDS; DIETARY SUPPLEMENTS; DNA METHYLATION; DOUBLE-BLIND METHOD; EPIGENESIS, GENETIC; FEMALE; FERTILIZATION; FETAL BLOOD; GAMBIA; GENOMIC IMPRINTING; HUMANS; INFANT; INFANT, NEWBORN; MALE; MALNUTRITION; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MICRONUTRIENTS; MIDDLE AGED; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; SEX CHARACTERISTICS; YOUNG ADULT;

EID: 84859222932     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds026     Document Type: Article

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