Synthesis and anticancer activity of heteroaromatic linked 4β-amido podophyllotoxins as apoptotic inducing agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 273-280

  Kamal, Ahmed ^a   Tamboli, Jaki R ^a   Vishnuvardhan, M V P S ^a   Adil, S F ^b   Nayak, V Lakshma ^a   Ramakrishna, S ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Anticancer activity; Apoptosis; Caspase 3; Cell cycle analysis; Podophyllotoxin

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; ETOPOSIDE; PODOPHYLLOTOXIN DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; COLON CANCER; DNA FRAGMENTATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; KIDNEY CANCER; LUNG CANCER; MELANOMA; STAINING; UTERINE CERVIX CANCER;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; DNA; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; G2 PHASE CELL CYCLE CHECKPOINTS; HELA CELLS; HETEROCYCLIC COMPOUNDS; HT29 CELLS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MICE; PODOPHYLLOTOXIN;

EID: 84870987392     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.099     Document Type: Article

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