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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4778-4782

Synthesis and biological evaluation of novel 4β-(1,3,4-oxadiazole-2- amino)-podophyllotoxin derivatives

(5) Ren, Jie a Wu, Lin a Xin, Wen Qun a Chen, Xin a Hu, Kun a

a CHANGZHOU UNIVERSITY (China)

Author keywords

1,3,4 Oxadiazole; Antitumor activity; Mechanism; Podophyllotoxin; Topoisomerase II

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 4BETA (1,3,4 OXADIAZOLE 2 AMINO)PODOPHYLLOTOXIN DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; FLUOROURACIL; PODOPHYLLOTOXIN; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; S PHASE CELL CYCLE CHECKPOINT; TUMOR CELL LINE; VERO CELL;

ANIMALS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MOLECULAR STRUCTURE; PODOPHYLLOTOXIN; STRUCTURE-ACTIVITY RELATIONSHIP; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS;

EID: 84863460053 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.05.059 Document Type: Article

Times cited : (52)

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