Argirein alleviates corpus cavernosum dysfunction by suppressing pro-inflammatory factors p66Shc and ER stress chaperone Bip in diabetic rats

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 1, 2013, Pages 94-101

  Cheng, Yu Si ^a   Cong, Xiao Dong ^b   Dai, De Zai ^a   Zhang, Yun ^b   Dai, Yin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Bip; diabetes mellitus; erectile dysfunction; NO; p66Shc

Indexed keywords

ADAPTOR PROTEIN; AMINOGUANIDINE; ANTIINFLAMMATORY AGENT; ARGININE; ARGIREIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; PROTEIN P66SHC; REACTIVE OXYGEN METABOLITE; RHEIN; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CORPUS CAVERNOSUM; DIABETES MELLITUS; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ERECTILE DYSFUNCTION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; STREPTOZOCIN DIABETES; UPREGULATION;

ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARGININE; BIOLOGICAL MARKERS; DIABETIC ANGIOPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; ERECTILE DYSFUNCTION; GENE EXPRESSION REGULATION; GUANIDINES; HEAT-SHOCK PROTEINS; MALE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PENIS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SHC SIGNALING ADAPTOR PROTEINS; VASOCONSTRICTION; VASODILATION;

EID: 84870946254     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01565.x     Document Type: Article

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