메뉴 건너뛰기




Volumn 299, Issue 3, 2010, Pages

Hypoxic relaxation of penile arteries: Involvement of endothelial nitric oxide and modulation by reactive oxygen species

Author keywords

Diet induced obesity; Hypoxia; Penile vascular regulation; Superoxide

Indexed keywords

ACETYLCHOLINE; APOCYNIN; CATALASE; EBSELEN; INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXIDE; PHENYLEPHRINE; PROSTAGLANDIN SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TEMPOL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; SUPEROXIDE DISMUTASE; VASODILATOR AGENT;

EID: 77956657156     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00382.2010     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 33644681926 scopus 로고    scopus 로고
    • Hydrogen peroxide as a paracrine vascular mediator: Regulation and signaling leading to dysfunction
    • Ardanaz N, Pagano PJ. Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction. Exp Biol Med (Maywood) 231: 237-251, 2006.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 237-251
    • Ardanaz, N.1    Pagano, P.J.2
  • 2
    • 0028797256 scopus 로고
    • Hemodynamics of penile erection: III. Measurement of deep intracavernosal and subtunical blood flow and oxygen tension
    • Azadzoi KM, Vlachiotis J, Pontari M, Siroky MB. Hemodynamics of penile erection: III. Measurement of deep intracavernosal and subtunical blood flow and oxygen tension. J Urol 153: 521-526, 1995.
    • (1995) J Urol , vol.153 , pp. 521-526
    • Azadzoi, K.M.1    Vlachiotis, J.2    Pontari, M.3    Siroky, M.B.4
  • 3
    • 1942501869 scopus 로고    scopus 로고
    • Effect of Chronic Ischemia on Constitutive and Inducible Nitric Oxide Synthase Expression in Erectile Tissue
    • Azadzoi KM, Master TA, Siroky MB. Effect of chronic ischemia on constitutive and inducible nitric oxide synthase expression in erectile tissue. J Androl 25: 382-388, 2004. (Pubitemid 38509236)
    • (2004) Journal of Andrology , vol.25 , Issue.3 , pp. 382-388
    • Azadzoi, K.M.1    Master, T.A.2    Siroky, M.B.3
  • 4
    • 20444461230 scopus 로고    scopus 로고
    • Oxidative stress in arteriogenic erectile dysfunction: Prophylactic role of antioxidants
    • Azadzoi KM, Schulman RN, Aviram M, Siroky MB. Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants. J Urol 174: 386-393, 2005.
    • (2005) J Urol , vol.174 , pp. 386-393
    • Azadzoi, K.M.1    Schulman, R.N.2    Aviram, M.3    Siroky, M.B.4
  • 5
    • 0027771135 scopus 로고
    • Reversal of sexual impotence in male patients with chronic obstructive pulmonary disease and hypoxemia with long-term oxygen therapy
    • Aasebø U, Gyltnes A, Bremnes RM, Aakvaag A, Slørdal L. Reversal of sexual impotence in male patients with chronic obstructive pulmonary disease and hypoxemia with long-term oxygen therapy. J Steroid Biochem Mol Biol 46: 799-803, 1993.
    • (1993) J Steroid Biochem Mol Biol , vol.46 , pp. 799-803
    • Aasebø, U.1    Gyltnes, A.2    Bremnes, R.M.3    Aakvaag, A.4    Slørdal, L.5
  • 6
    • 0141788776 scopus 로고    scopus 로고
    • Superoxide-NO interaction decreases flow- And agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus
    • Bagi Z, Koller A, Kaley G. Superoxide-NO interaction decreases flowand agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 285: H1404-H1410, 2003. (Pubitemid 37169492)
    • (2003) American Journal of Physiology - Heart and Circulatory Physiology , vol.285 , Issue.4
    • Bagi, Z.1    Koller, A.2    Kaley, G.3
  • 7
    • 33751171952 scopus 로고    scopus 로고
    • High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: Role of xanthine oxidase-derived superoxide anion
    • Erdei N, Tóth A, Pásztor ET, Papp Z, Edes I, Koller A, Bagi Z. High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion. Am J Physiol Heart Circ Physiol 291: H2107-H2115, 2006.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Erdei, N.1    Tóth, A.2    Pásztor, E.T.3    Papp, Z.4    Edes, I.5    Koller, A.6    Bagi, Z.7
  • 9
    • 77955887715 scopus 로고    scopus 로고
    • Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: Implications in diet-induced obesity
    • In press
    • Feher A, Rutkai I, Beleznai T, Ungvari Z, Csiszar A, Edes I, Bagi Z. Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity. Cardiovasc Res. In press.
    • Cardiovasc Res.
    • Feher, A.1    Rutkai, I.2    Beleznai, T.3    Ungvari, Z.4    Csiszar, A.5    Edes, I.6    Bagi, Z.7
  • 10
    • 0034791189 scopus 로고    scopus 로고
    • Impaired dilation of skeletal muscle microvessels to reduced oxygen tension in diabetic obese Zucker rats
    • Frisbee JC. Impaired dilation of skeletal muscle microvessels to reduced oxygen tension in diabetic obese Zucker rats. Am J Physiol Heart Circ Physiol 281: H1568-H1574, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Frisbee, J.C.1
  • 12
    • 29544435525 scopus 로고    scopus 로고
    • Endothelial and erectile dysfunction, diabetes mellitus, and the metabolic syndrome: Common pathways and treatments?
    • DOI 10.1016/j.amjcard.2005.07.005, PII S0002914905011203, A Symposium: Sexual Dysfunction and Cardiac Risk
    • Fonseca VA, Jawa A. Endothelial and erectile dysfunction, diabetes mellitus, and the metabolic syndrome: common pathways and treatments? Am J Cardiol 96: 13M-18M, 2005. (Pubitemid 43017211)
    • (2005) American Journal of Cardiology , vol.96 , Issue.12 SUPPL. 2
    • Fonseca, V.1    Jawa, A.2
  • 13
    • 72249107744 scopus 로고    scopus 로고
    • Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase
    • Gao Q, Zhao X, Ahmad M, Wolin MS. Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase. Am J Physiol Heart Circ Physiol 297: H2262-H2269, 2009.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Gao, Q.1    Zhao, X.2    Ahmad, M.3    Wolin, M.S.4
  • 14
    • 57049186709 scopus 로고    scopus 로고
    • Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension
    • Goodwill AG, James ME, Frisbee JC. Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension. Am J Physiol Heart Circ Physiol 295: H1522-H1528, 2008.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Goodwill, A.G.1    James, M.E.2    Frisbee, J.C.3
  • 17
    • 33744936788 scopus 로고    scopus 로고
    • Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH
    • Gupte SA, Wolin MS. Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH. Am J Physiol Heart Circ Physiol 290: H2228-H2238, 2006.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Gupte, S.A.1    Wolin, M.S.2
  • 19
    • 0036285223 scopus 로고    scopus 로고
    • Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels
    • Guzik TJ, West NE, Pillai R, Taggart DP, Channon KM. Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels. Hypertension 39: 1088-1094, 2002.
    • (2002) Hypertension , vol.39 , pp. 1088-1094
    • Guzik, T.J.1    West, N.E.2    Pillai, R.3    Taggart, D.P.4    Channon, K.M.5
  • 20
    • 0035000258 scopus 로고    scopus 로고
    • Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: A comparison between hypoxia and inhibitors of cell metabolism
    • DOI 10.1002/jcp.1092
    • Hoffmann A, Gloe T, Pohl U. Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia, and inhibitors of cell metabolism. J Cell Physiol 188: 33-44, 2001. (Pubitemid 32476494)
    • (2001) Journal of Cellular Physiology , vol.188 , Issue.1 , pp. 33-44
    • Hoffmann, A.1    Gloe, T.2    Pohl, U.3
  • 24
    • 33644840773 scopus 로고    scopus 로고
    • Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice
    • Liu Y, Bubolz AH, Shi Y, Newman PJ, Newman DK, Gutterman DD. Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. Am J Physiol Regul Integr Comp Physiol 290: R57-R65, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Liu, Y.1    Bubolz, A.H.2    Shi, Y.3    Newman, P.J.4    Newman, D.K.5    Gutterman, D.D.6
  • 25
    • 18844397807 scopus 로고    scopus 로고
    • Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries
    • Lucchesi PA, Belmadani S, Matrougui K. Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries. J Hypertens 23: 571-579, 2005. (Pubitemid 40684716)
    • (2005) Journal of Hypertension , vol.23 , Issue.3 , pp. 571-579
    • Lucchesi, P.A.1    Belmadani, S.2    Matrougui, K.3
  • 26
    • 33645740880 scopus 로고    scopus 로고
    • Adenosine and hypoxic dilation of rat coronary small arteries: Roles of the ATP-sensitive potassium channel, endothelium, and nitric oxide
    • Lynch FM, Austin C, Heagerty AM, Izzard AS. Adenosine and hypoxic dilation of rat coronary small arteries: roles of the ATP-sensitive potassium channel, endothelium, and nitric oxide. Am J Physiol Heart Circ Physiol 290: H1145-H1150, 2006.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Lynch, F.M.1    Austin, C.2    Heagerty, A.M.3    Izzard, A.S.4
  • 28
    • 0030034735 scopus 로고    scopus 로고
    • The reaction of ebselen with peroxynitrite
    • Masumoto H, Sies H. The reaction of ebselen with peroxynitrite. Chem Res Toxicol 9: 262-267, 1996.
    • (1996) Chem Res Toxicol , vol.9 , pp. 262-267
    • Masumoto, H.1    Sies, H.2
  • 30
    • 62149085591 scopus 로고    scopus 로고
    • Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia
    • Mikula I, Durocher S, Martasek P, Mutus B, Slama-Schwok A. Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia. Biochem J 418: 673-682, 2009.
    • (2009) Biochem J , vol.418 , pp. 673-682
    • Mikula, I.1    Durocher, S.2    Martasek, P.3    Mutus, B.4    Slama-Schwok, A.5
  • 33
    • 30444439216 scopus 로고    scopus 로고
    • The discovery of nitric oxide and its role in vascular biology
    • Moncada S, Higgs EA. The discovery of nitric oxide and its role in vascular biology. Br J Pharmacol 147, Suppl 1: S193-S201, 2006.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Moncada, S.1    Higgs, E.A.2
  • 34
    • 0037752795 scopus 로고    scopus 로고
    • Is erectile dysfunction the "tip of the iceberg" of a systemic vascular disorder?
    • Montorsi P, Montorsi F, Schulman CC. Is erectile dysfunction the "tip of the iceberg" of a systemic vascular disorder? Eur Urol 44: 352-354, 2003.
    • (2003) Eur Urol , vol.44 , pp. 352-354
    • Montorsi, P.1    Montorsi, F.2    Schulman, C.C.3
  • 35
    • 0017702173 scopus 로고
    • Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats
    • Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 41: 19-26, 1977. (Pubitemid 8132079)
    • (1977) Circulation Research , vol.41 , Issue.1 , pp. 19-26
    • Mulvany, M.J.1    Halpern, W.2
  • 36
    • 16844377787 scopus 로고    scopus 로고
    • Acute hypoxia simultaneously induces the expression of gp91phox and endothelial nitric oxide synthase in the porcine pulmonary artery
    • Muzaffar S, Shukla N, Angelini GD, Jeremy JY. Acute hypoxia simultaneously induces the expression of gp91phox and endothelial nitric oxide synthase in the porcine pulmonary artery. Thorax 60: 305-313, 2005.
    • (2005) Thorax , vol.60 , pp. 305-313
    • Muzaffar, S.1    Shukla, N.2    Angelini, G.D.3    Jeremy, J.Y.4
  • 37
    • 41149150716 scopus 로고    scopus 로고
    • NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
    • Paravicini TM, Touyz RM. NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 31: S170-S180, 2008.
    • (2008) Diabetes Care , vol.31
    • Paravicini, T.M.1    Touyz, R.M.2
  • 38
    • 0026800747 scopus 로고
    • Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase- Derived metabolites
    • Park KH, Rubin LE, Gross SS, Levi R. Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase- derived metabolites. Circ Res 71: 992-1001, 1992.
    • (1992) Circ Res , vol.71 , pp. 992-1001
    • Park, K.H.1    Rubin, L.E.2    Gross, S.S.3    Levi, R.4
  • 40
    • 38149051425 scopus 로고    scopus 로고
    • Physiological regulation of penile arteries and veins
    • Prieto D. Physiological regulation of penile arteries and veins. Int J Impot Res 20: 17-29, 2008.
    • (2008) Int J Impot Res , vol.20 , pp. 17-29
    • Prieto, D.1
  • 46
    • 33750449016 scopus 로고    scopus 로고
    • Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells
    • DOI 10.1161/01.RES.0000247068.75808.3f, PII 0000301220061027000010
    • Waypa GB, Guzy R, Mungai PT, Mack MM, Marks JD, Roe MW, Schumacker PT. Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circ Res 99: 970-978, 2006. (Pubitemid 44657800)
    • (2006) Circulation Research , vol.99 , Issue.9 , pp. 970-978
    • Waypa, G.B.1    Guzy, R.2    Mungai, P.T.3    Mack, M.M.4    Marks, J.D.5    Roe, M.W.6    Schumacker, P.T.7
  • 47
    • 33947129737 scopus 로고    scopus 로고
    • Altered penile vascular reactivity, and erection in the Zucker obese-diabetic rat
    • Wingard C, Fulton D, Husain S. Altered penile vascular reactivity, and erection in the Zucker obese-diabetic rat. J Sex Med 4: 348-462, 2007.
    • (2007) J Sex Med , vol.4 , pp. 348-462
    • Wingard, C.1    Fulton, D.2    Husain, S.3
  • 48
    • 64049083005 scopus 로고    scopus 로고
    • Reactive oxygen species and the control of vascular function
    • Wolin MS. Reactive oxygen species and the control of vascular function. Am J Physiol Heart Circ Physiol 296: H539-H549, 2009.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Wolin, M.S.1
  • 49
    • 35348815023 scopus 로고    scopus 로고
    • Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells
    • Wu W, Platoshyn O, Firth AL, Yuan JX. Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 293: L952-L959, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Wu, W.1    Platoshyn, O.2    Firth, A.L.3    Yuan, J.X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.