-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman, D. Aging: A theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11, 298-300.
-
(1956)
J. Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
2
-
-
0028349236
-
Decline with age of the respiratory chain activity in human skeletal muscle
-
Boffoli, D.; Scacco, S.C.; Vergari, R.; Solarino, G.; Santacroce, G.; Papa, S. Decline with age of the respiratory chain activity in human skeletal muscle. Biochim. Biophys. Acta 1994, 1226, 73-82.
-
(1994)
Biochim. Biophys. Acta
, vol.1226
, pp. 73-82
-
-
Boffoli, D.1
Scacco, S.C.2
Vergari, R.3
Solarino, G.4
Santacroce, G.5
Papa, S.6
-
3
-
-
0032423013
-
The effects of dietary restriction on mitochondrial dysfunction in aging
-
Feuers, R.J. The effects of dietary restriction on mitochondrial dysfunction in aging. Ann. N. Y. Acad. Sci. 1998, 854, 192-201.
-
(1998)
Ann. N. Y. Acad. Sci
, vol.854
, pp. 192-201
-
-
Feuers, R.J.1
-
4
-
-
0033958726
-
Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse
-
Kwong, L.K.; Sohal, R.S. Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse. Arch. Biochem. Biophys. 2000, 373, 16-22.
-
(2000)
Arch. Biochem. Biophys
, vol.373
, pp. 16-22
-
-
Kwong, L.K.1
Sohal, R.S.2
-
5
-
-
9844226198
-
Mitochondrial complex I defects in aging
-
Lenaz, G.; Bovina, C.; Castelluccio, C.; Fato, R.; Formiggini, G.; Genova, M.L.; Marchetti, M.; Pich, M.M.; Pallotti, F.; Parenti Castelli, G.; et al. Mitochondrial complex I defects in aging. Mol. Cell. Biochem. 1997, 174, 329-333.
-
(1997)
Mol. Cell. Biochem
, vol.174
, pp. 329-333
-
-
Lenaz, G.1
Bovina, C.2
Castelluccio, C.3
Fato, R.4
Formiggini, G.5
Genova, M.L.6
Marchetti, M.7
Pich, M.M.8
Pallotti, F.9
Parenti Castelli, G.10
-
6
-
-
0031974019
-
Mitochondrial dysfunction in the senescence accelerated mouse (SAM)
-
Nakahara, H.; Kanno, T.; Inai, Y.; Utsumi, K.; Hiramatsu, M.; Mori, A.; Packer, L. Mitochondrial dysfunction in the senescence accelerated mouse (SAM). Free Radic. Biol. Med. 1998, 24, 85-92.
-
(1998)
Free Radic. Biol. Med
, vol.24
, pp. 85-92
-
-
Nakahara, H.1
Kanno, T.2
Inai, Y.3
Utsumi, K.4
Hiramatsu, M.5
Mori, A.6
Packer, L.7
-
7
-
-
0036084827
-
Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice
-
Navarro, A.; Sanchez Del Pino, M.J.; Gomez, C.; Peralta, J.L.; Boveris, A. Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 282, R985-R992.
-
(2002)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.282
-
-
Navarro, A.1
Sanchez del Pino, M.J.2
Gomez, C.3
Peralta, J.L.4
Boveris, A.5
-
8
-
-
0034988397
-
Oxidative damage to mitochondria and aging
-
Van Remmen, H.; Richardson, A. Oxidative damage to mitochondria and aging. Exp. Gerontol. 2001, 36, 957-968.
-
(2001)
Exp. Gerontol
, vol.36
, pp. 957-968
-
-
van Remmen, H.1
Richardson, A.2
-
9
-
-
0028235259
-
Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria
-
Hsieh, R.H.; Hou, J.H.; Hsu, H.S.; Wei, Y.H. Age-dependent respiratory function decline and DNA deletions in human muscle mitochondria. Biochem. Mol. Biol. Int. 1994, 32, 1009-1022.
-
(1994)
Biochem. Mol. Biol. int
, vol.32
, pp. 1009-1022
-
-
Hsieh, R.H.1
Hou, J.H.2
Hsu, H.S.3
Wei, Y.H.4
-
10
-
-
0024980878
-
Liver mitochondrial respiratory functions decline with age
-
Yen, T.C.; Chen, Y.S.; King, K.L.; Yeh, S.H.; Wei, Y.H. Liver mitochondrial respiratory functions decline with age. Biochem. Biophys. Res. Commun. 1989, 165, 944-1003.
-
(1989)
Biochem. Biophys. Res. Commun
, vol.165
, pp. 944-1003
-
-
Yen, T.C.1
Chen, Y.S.2
King, K.L.3
Yeh, S.H.4
Wei, Y.H.5
-
11
-
-
0141483496
-
Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts
-
Greco, M.; Villani, G.; Mazzucchelli, F.; Bresolin, N.; Papa, S.; Attardi, G. Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J. 2003, 17, 1706-1708.
-
(2003)
FASEB J
, vol.17
, pp. 1706-1708
-
-
Greco, M.1
Villani, G.2
Mazzucchelli, F.3
Bresolin, N.4
Papa, S.5
Attardi, G.6
-
12
-
-
77953806512
-
Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders
-
Lebiedzinska, M.; Karkucinska-Wieckowska, A.; Giorgi, C.; Karczmarewicz, E.; Pronicka, E.; Pinton, P.; Duszynski, J.; Pronicki, M.; Wieckowski, M.R. Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders. Biochim. Biophys. Acta 2010, 1797, 952-960.
-
(2010)
Biochim. Biophys. Acta
, vol.1797
, pp. 952-960
-
-
Lebiedzinska, M.1
Karkucinska-Wieckowska, A.2
Giorgi, C.3
Karczmarewicz, E.4
Pronicka, E.5
Pinton, P.6
Duszynski, J.7
Pronicki, M.8
Wieckowski, M.R.9
-
13
-
-
67349112394
-
Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues
-
Lebiedzinska, M.; Duszynski, J.; Rizzuto, R.; Pinton, P.; Wieckowski, M.R. Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues. Arch. Biochem. Biophys. 2009, 486, 73-80.
-
(2009)
Arch. Biochem. Biophys
, vol.486
, pp. 73-80
-
-
Lebiedzinska, M.1
Duszynski, J.2
Rizzuto, R.3
Pinton, P.4
Wieckowski, M.R.5
-
14
-
-
0016711140
-
The effect of age on mitochondrial ultrastructure
-
Wilson, P.D.; Franks, L.M. The effect of age on mitochondrial ultrastructure. Gerontology 1975, 21, 81-94.
-
(1975)
Gerontology
, vol.21
, pp. 81-94
-
-
Wilson, P.D.1
Franks, L.M.2
-
15
-
-
10044230496
-
Influence of a mitochondrial genetic defect on capacitative calcium entry and mitochondrial organization in the osteosarcoma cells
-
Szczepanowska, J.; Zablocki, K.; Duszynski, J. Influence of a mitochondrial genetic defect on capacitative calcium entry and mitochondrial organization in the osteosarcoma cells. FEBS Lett. 2004, 578, 316-322.
-
(2004)
FEBS Lett
, vol.578
, pp. 316-322
-
-
Szczepanowska, J.1
Zablocki, K.2
Duszynski, J.3
-
16
-
-
34347213728
-
Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu, Zn-superoxide dismutase activity: Implications for mitochondrial energy metabolism and apoptosis
-
Inarrea, P.; Moini, H.; Han, D.; Rettori, D.; Aguilo, I.; Alava, M.A.; Iturralde, M.; Cadenas, E. Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu, Zn-superoxide dismutase activity: Implications for mitochondrial energy metabolism and apoptosis. Biochem. J. 2007, 405, 173-179.
-
(2007)
Biochem. J
, vol.405
, pp. 173-179
-
-
Inarrea, P.1
Moini, H.2
Han, D.3
Rettori, D.4
Aguilo, I.5
Alava, M.A.6
Iturralde, M.7
Cadenas, E.8
-
17
-
-
0028170326
-
Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress
-
Michiels, C.; Raes, M.; Toussaint, O.; Remacle, J. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic. Biol. Med. 1994, 17, 235-248.
-
(1994)
Free Radic. Biol. Med
, vol.17
, pp. 235-248
-
-
Michiels, C.1
Raes, M.2
Toussaint, O.3
Remacle, J.4
-
18
-
-
0036790385
-
Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
-
Wei, Y.H.; Lee, H.C. Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp. Biol. Med. 2002, 227, 671-682.
-
(2002)
Exp. Biol. Med
, vol.227
, pp. 671-682
-
-
Wei, Y.H.1
Lee, H.C.2
-
19
-
-
2942556985
-
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
-
Van Remmen, H.; Qi, W.; Sabia, M.; Freeman, G.; Estlack, L.; Yang, H.; Guo, Z.M.; Huang, T.T.; Strong, R.; Lee, S.; et al. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radic. Biol. Med. 2004, 36, 1625-1634.
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 1625-1634
-
-
van Remmen, H.1
Qi, W.2
Sabia, M.3
Freeman, G.4
Estlack, L.5
Yang, H.6
Guo, Z.M.7
Huang, T.T.8
Strong, R.9
Lee, S.10
-
20
-
-
77956533160
-
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)
-
Hsieh, C.C.; Papaconstantinou, J. Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). Aging (Albany NY) 2009, 1, 784-802.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 784-802
-
-
Hsieh, C.C.1
Papaconstantinou, J.2
-
21
-
-
0032588780
-
Coenzyme Q10, a cutaneous antioxidant and energizer
-
Hoppe, U.; Bergemann, J.; Diembeck, W.; Ennen, J.; Gohla, S.; Harris, I.; Jacob, J.; Kielholz, J.; Mei, W.; Pollet, D.; et al. Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors 1999, 9, 371-378.
-
(1999)
Biofactors
, vol.9
, pp. 371-378
-
-
Hoppe, U.1
Bergemann, J.2
Diembeck, W.3
Ennen, J.4
Gohla, S.5
Harris, I.6
Jacob, J.7
Kielholz, J.8
Mei, W.9
Pollet, D.10
-
22
-
-
0036223839
-
Photoaging is associated with protein oxidation in human skin in vivo
-
Sander, C.S.; Chang, H.; Salzmann, S.; Muller, C.S.; Ekanayake-Mudiyanselage, S.; Elsner, P.; Thiele, J.J. Photoaging is associated with protein oxidation in human skin in vivo. J. Invest. Dermatol. 2002, 118, 618-625.
-
(2002)
J. Invest. Dermatol
, vol.118
, pp. 618-625
-
-
Sander, C.S.1
Chang, H.2
Salzmann, S.3
Muller, C.S.4
Ekanayake-Mudiyanselage, S.5
Elsner, P.6
Thiele, J.J.7
-
23
-
-
0033016467
-
Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion
-
Berneburg, M.; Grether-Beck, S.; Kurten, V.; Ruzicka, T.; Briviba, K.; Sies, H.; Krutmann, J. Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion. J. Biol. Chem. 1999, 274, 15345-15349.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 15345-15349
-
-
Berneburg, M.1
Grether-Beck, S.2
Kurten, V.3
Ruzicka, T.4
Briviba, K.5
Sies, H.6
Krutmann, J.7
-
24
-
-
36649011797
-
Interaction of vitamins C and E as better cosmeceuticals
-
Burke, K.E. Interaction of vitamins C and E as better cosmeceuticals. Dermatol. Ther. 2007, 20, 314-321.
-
(2007)
Dermatol. Ther
, vol.20
, pp. 314-321
-
-
Burke, K.E.1
-
25
-
-
0016362593
-
Extension of the lifespan of cultured normal human diploid cells by vitamin E
-
Packer, L.; Smith, J.R. Extension of the lifespan of cultured normal human diploid cells by vitamin E. Proc. Natl. Acad. Sci. USA 1974, 71, 4763-4767.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 4763-4767
-
-
Packer, L.1
Smith, J.R.2
-
26
-
-
33744988093
-
Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts
-
Stockl, P.; Hutter, E.; Zwerschke, W.; Jansen-Durr, P. Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts. Exp. Gerontol. 2006, 41, 674-682.
-
(2006)
Exp. Gerontol
, vol.41
, pp. 674-682
-
-
Stockl, P.1
Hutter, E.2
Zwerschke, W.3
Jansen-Durr, P.4
-
27
-
-
77953490083
-
The effect of aging and increasing ascorbate concentrations on respiratory chain activity in cultured human fibroblasts
-
Ghneim, H.K.; Al-Sheikh, Y.A. The effect of aging and increasing ascorbate concentrations on respiratory chain activity in cultured human fibroblasts. Cell Biochem. Funct. 2010, 28, 283-292.
-
(2010)
Cell Biochem. Funct
, vol.28
, pp. 283-292
-
-
Ghneim, H.K.1
Al-Sheikh, Y.A.2
-
28
-
-
77449147298
-
Skin photoprotection by natural polyphenols: Anti-inflammatory, antioxidant and DNA repair mechanisms
-
Nichols, J.A.; Katiyar, S.K. Skin photoprotection by natural polyphenols: Anti-inflammatory, antioxidant and DNA repair mechanisms. Arch. Dermatol. Res. 2010, 302, 71-83.
-
(2010)
Arch. Dermatol. Res
, vol.302
, pp. 71-83
-
-
Nichols, J.A.1
Katiyar, S.K.2
-
29
-
-
39949085055
-
Effects of epigallocatechin-3-gallate on mitochondrial integrity and antioxidative enzyme activity in the aging process of human fibroblast
-
Meng, Q.; Velalar, C.N.; Ruan, R. Effects of epigallocatechin-3-gallate on mitochondrial integrity and antioxidative enzyme activity in the aging process of human fibroblast. Free Radic. Biol. Med. 2008, 44, 1032-1041.
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 1032-1041
-
-
Meng, Q.1
Velalar, C.N.2
Ruan, R.3
-
30
-
-
78649323827
-
Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts
-
Ramachandran, S.; Rajendra Prasad, N.; Karthikeyan, S. Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts. Arch. Dermatol. Res. 2010, 302, 733-744.
-
(2010)
Arch. Dermatol. Res
, vol.302
, pp. 733-744
-
-
Ramachandran, S.1
Rajendra Prasad, N.2
Karthikeyan, S.3
-
31
-
-
67349283471
-
An attempt to prevent senescence: A mitochondrial approach
-
Skulachev, V.P.; Anisimov, V.N.; Antonenko, Y.N.; Bakeeva, L.E.; Chernyak, B.V.; Erichev, V.P.; Filenko, O.F.; Kalinina, N.I.; Kapelko, V.I.; Kolosova, N.G.; et al. An attempt to prevent senescence: A mitochondrial approach. Biochim. Biophys. Acta 2009, 1787, 437-461.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 437-461
-
-
Skulachev, V.P.1
Anisimov, V.N.2
Antonenko, Y.N.3
Bakeeva, L.E.4
Chernyak, B.V.5
Erichev, V.P.6
Filenko, O.F.7
Kalinina, N.I.8
Kapelko, V.I.9
Kolosova, N.G.10
-
32
-
-
33846817351
-
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
-
Pinton, P.; Rimessi, A.; Marchi, S.; Orsini, F.; Migliaccio, E.; Giorgio, M.; Contursi, C.; Minucci, S.; Mantovani, F.; Wieckowski, M.R.; et al. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science 2007, 315, 659-663.
-
(2007)
Science
, vol.315
, pp. 659-663
-
-
Pinton, P.1
Rimessi, A.2
Marchi, S.3
Orsini, F.4
Migliaccio, E.5
Giorgio, M.6
Contursi, C.7
Minucci, S.8
Mantovani, F.9
Wieckowski, M.R.10
-
33
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio, E.; Giorgio, M.; Mele, S.; Pelicci, G.; Reboldi, P.; Pandolfi, P.P.; Lanfrancone, L.; Pelicci, P.G. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 1999, 402, 309-313.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
34
-
-
74049115059
-
Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice
-
Tomilov, A.A.; Bicocca, V.; Schoenfeld, R.A.; Giorgio, M.; Migliaccio, E.; Ramsey, J.J.; Hagopian, K.; Pelicci, P.G.; Cortopassi, G.A. Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice. J. Biol. Chem. 2010, 285, 1153-1165.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 1153-1165
-
-
Tomilov, A.A.1
Bicocca, V.2
Schoenfeld, R.A.3
Giorgio, M.4
Migliaccio, E.5
Ramsey, J.J.6
Hagopian, K.7
Pelicci, P.G.8
Cortopassi, G.A.9
-
35
-
-
46749102196
-
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity
-
Finetti, F.; Pellegrini, M.; Ulivieri, C.; Savino, M.T.; Paccagnini, E.; Ginanneschi, C.; Lanfrancone, L.; Pelicci, P.G.; Baldari, C.T. The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity. Blood 2008, 111, 5017-5027.
-
(2008)
Blood
, vol.111
, pp. 5017-5027
-
-
Finetti, F.1
Pellegrini, M.2
Ulivieri, C.3
Savino, M.T.4
Paccagnini, E.5
Ginanneschi, C.6
Lanfrancone, L.7
Pelicci, P.G.8
Baldari, C.T.9
-
36
-
-
0033669885
-
Evolution of Shc functions from nematode to human
-
Luzi, L.; Confalonieri, S.; Di Fiore, P.P.; Pelicci, P.G. Evolution of Shc functions from nematode to human. Curr. Opin. Genet. Dev. 2000, 10, 668-674.
-
(2000)
Curr. Opin. Genet. Dev
, vol.10
, pp. 668-674
-
-
Luzi, L.1
Confalonieri, S.2
di Fiore, P.P.3
Pelicci, P.G.4
-
37
-
-
85047695800
-
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
-
Trinei, M.; Giorgio, M.; Cicalese, A.; Barozzi, S.; Ventura, A.; Migliaccio, E.; Milia, E.; Padura, I.M.; Raker, V.A.; Maccarana, M.; et al. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene 2002, 21, 3872-3878.
-
(2002)
Oncogene
, vol.21
, pp. 3872-3878
-
-
Trinei, M.1
Giorgio, M.2
Cicalese, A.3
Barozzi, S.4
Ventura, A.5
Migliaccio, E.6
Milia, E.7
Padura, I.M.8
Raker, V.A.9
McCarana, M.10
-
38
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio, M.; Migliaccio, E.; Orsini, F.; Paolucci, D.; Moroni, M.; Contursi, C.; Pelliccia, G.; Luzi, L.; Minucci, S.; Marcaccio, M.; et al. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 2005, 122, 221-233.
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
-
39
-
-
0030783255
-
The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway
-
Okada, S.; Kao, A.W.; Ceresa, B.P.; Blaikie, P.; Margolis, B.; Pessin, J.E. The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. J. Biol. Chem. 1997, 272, 28042-28049.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 28042-28049
-
-
Okada, S.1
Kao, A.W.2
Ceresa, B.P.3
Blaikie, P.4
Margolis, B.5
Pessin, J.E.6
-
40
-
-
70350012303
-
Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
-
Wieckowski, M.R.; Giorgi, C.; Lebiedzinska, M.; Duszynski, J.; Pinton, P. Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells. Nat. Protoc. 2009, 4, 1582-1590.
-
(2009)
Nat. Protoc
, vol.4
, pp. 1582-1590
-
-
Wieckowski, M.R.1
Giorgi, C.2
Lebiedzinska, M.3
Duszynski, J.4
Pinton, P.5
-
41
-
-
68949192292
-
Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles
-
Lebiedzinska, M.; Szabadkai, G.; Jones, A.W.; Duszynski, J.; Wieckowski, M.R. Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles. Int. J. Biochem. Cell Biol. 2009, 41, 1805-1816.
-
(2009)
Int. J. Biochem. Cell Biol
, vol.41
, pp. 1805-1816
-
-
Lebiedzinska, M.1
Szabadkai, G.2
Jones, A.W.3
Duszynski, J.4
Wieckowski, M.R.5
-
42
-
-
33744519939
-
The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism
-
Nemoto, S.; Combs, C.A.; French, S.; Ahn, B.H.; Fergusson, M.M.; Balaban, R.S.; Finkel, T. The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism. J. Biol. Chem. 2006, 281, 10555-10560.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 10555-10560
-
-
Nemoto, S.1
Combs, C.A.2
French, S.3
Ahn, B.H.4
Fergusson, M.M.5
Balaban, R.S.6
Finkel, T.7
-
43
-
-
34548148201
-
Hydrogen peroxide: A metabolic by-product or a common mediator of ageing signals?
-
Giorgio, M.; Trinei, M.; Migliaccio, E.; Pelicci, P.G. Hydrogen peroxide: A metabolic by-product or a common mediator of ageing signals? Nat. Rev. Mol. Cell Biol. 2007, 8, 722-728.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 722-728
-
-
Giorgio, M.1
Trinei, M.2
Migliaccio, E.3
Pelicci, P.G.4
-
44
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
Napoli, C.; Martin-Padura, I.; de Nigris, F.; Giorgio, M.; Mansueto, G.; Somma, P.; Condorelli, M.; Sica, G.; de Rosa, G.; Pelicci, P. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc. Natl. Acad. Sci. USA 2003, 100, 2112-2116.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
de Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
de Rosa, G.9
Pelicci, P.10
-
45
-
-
57749091893
-
p66Shc-generated oxidative signal promotes fat accumulation
-
Berniakovich, I.; Trinei, M.; Stendardo, M.; Migliaccio, E.; Minucci, S.; Bernardi, P.; Pelicci, P.G.; Giorgio, M. p66Shc-generated oxidative signal promotes fat accumulation. J. Biol. Chem. 2008, 283, 34283-34293.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 34283-34293
-
-
Berniakovich, I.1
Trinei, M.2
Stendardo, M.3
Migliaccio, E.4
Minucci, S.5
Bernardi, P.6
Pelicci, P.G.7
Giorgio, M.8
-
46
-
-
77955798757
-
Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance
-
Ranieri, S.C.; Fusco, S.; Panieri, E.; Labate, V.; Mele, M.; Tesori, V.; Ferraraa, A.; Mauluccib, G.; de Spiritob, M.; Martorana, G.E.; et al. Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance. Proc. Natl. Acad. Sci. USA 2010, 107, 13420-13425.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 13420-13425
-
-
Ranieri, S.C.1
Fusco, S.2
Panieri, E.3
Labate, V.4
Mele, M.5
Tesori, V.6
Ferraraa, A.7
Mauluccib, G.8
de Spiritob, M.9
Martorana, G.E.10
-
47
-
-
78651344799
-
The Shc locus regulates insulin signaling and adiposity in mammals
-
Tomilov, A.A.; Ramsey, J.J.; Hagopian, K.; Giorgio, M.; Kim, K.M.; Lam, A.; Migliaccio, E.; Lloyd, K.C.; Berniakovich, I.; Prolla, T.A.; et al. The Shc locus regulates insulin signaling and adiposity in mammals. Aging Cell 2011, 10, 55-65.
-
(2011)
Aging Cell
, vol.10
, pp. 55-65
-
-
Tomilov, A.A.1
Ramsey, J.J.2
Hagopian, K.3
Giorgio, M.4
Kim, K.M.5
Lam, A.6
Migliaccio, E.7
Lloyd, K.C.8
Berniakovich, I.9
Prolla, T.A.10
-
48
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
Nemoto, S.; Finkel, T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 2002, 295, 2450-2452.
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
49
-
-
59849108790
-
The p53-p66shc-Manganese Superoxide Dismutase (MnSOD) network: A mitochondrial intrigue to generate reactive oxygen species
-
Pani, G.; Koch, O.R.; Galeotti, T. The p53-p66shc-Manganese Superoxide Dismutase (MnSOD) network: A mitochondrial intrigue to generate reactive oxygen species. Int. J. Biochem. Cell Biol. 2009, 41, 1002-1005.
-
(2009)
Int. J. Biochem. Cell Biol
, vol.41
, pp. 1002-1005
-
-
Pani, G.1
Koch, O.R.2
Galeotti, T.3
-
50
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal, R.S.; Weindruch, R. Oxidative stress, caloric restriction, and aging. Science 1996, 273, 59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
51
-
-
0029007378
-
Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus)
-
Sohal, R.S.; Agarwal, S.; Sohal, B.H. Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus). Mech. Ageing Dev. 1995, 81, 15-25.
-
(1995)
Mech. Ageing Dev
, vol.81
, pp. 15-25
-
-
Sohal, R.S.1
Agarwal, S.2
Sohal, B.H.3
-
52
-
-
21344454467
-
p66(shc) is highly expressed in fibroblasts from centenarians
-
Pandolfi, S.; Bonafe, M.; Di Tella, L.; Tiberi, L.; Salvioli, S.; Monti, D.; Sorbi, S.; Franceschi, C. p66(shc) is highly expressed in fibroblasts from centenarians. Mech. Ageing Dev. 2005, 126, 839-844.
-
(2005)
Mech. Ageing Dev
, vol.126
, pp. 839-844
-
-
Pandolfi, S.1
Bonafe, M.2
di Tella, L.3
Tiberi, L.4
Salvioli, S.5
Monti, D.6
Sorbi, S.7
Franceschi, C.8
-
53
-
-
84856001449
-
p66Shc-related response to the oxidative stress in fibroblasts of NARP patients
-
to be submitted for publication
-
Lebiedzinska, M.; Karkucinska-Wieckowska, A.; Suski, J.M.; Szabadkai, G.; Wilczyński, G.; Wlodarczyk, J.; Pronicki, M.; Duszynski, J.; Pinton, P.; Wieckowski, M.R. p66Shc-related response to the oxidative stress in fibroblasts of NARP patients. Mitochondrion, 2011, to be submitted for publication.
-
(2011)
Mitochondrion
-
-
Lebiedzinska, M.1
Karkucinska-Wieckowska, A.2
Suski, J.M.3
Szabadkai, G.4
Wilczyński, G.5
Wlodarczyk, J.6
Pronicki, M.7
Duszynski, J.8
Pinton, P.9
Wieckowski, M.R.10
-
54
-
-
0345596416
-
Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging
-
Tian, L.; Cai, Q.; Wei, H. Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging. Free Radic. Biol. Med. 1998, 24, 1477-1484.
-
(1998)
Free Radic. Biol. Med
, vol.24
, pp. 1477-1484
-
-
Tian, L.1
Cai, Q.2
Wei, H.3
-
55
-
-
0035871677
-
Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes
-
Palomero, J.; Galan, A.I.; Munoz, M.E.; Tunon, M.J.; Gonzalez-Gallego, J.; Jimenez, R. Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes. Free Radic. Biol. Med. 2001, 30, 836-845.
-
(2001)
Free Radic. Biol. Med
, vol.30
, pp. 836-845
-
-
Palomero, J.1
Galan, A.I.2
Munoz, M.E.3
Tunon, M.J.4
Gonzalez-Gallego, J.5
Jimenez, R.6
-
56
-
-
33750218248
-
Amicarelli F Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells
-
Tatone, C.; Carbone, M.C.; Falone, S.; Aimola, P.; Giardinelli, A.; Caserta, D.; Marci, R.; Pandolfi, A.; Ragnelli, A.M. Amicarelli F Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells. Mol. Hum. Reprod. 2006, 12, 655-660.
-
(2006)
Mol. Hum. Reprod
, vol.12
, pp. 655-660
-
-
Tatone, C.1
Carbone, M.C.2
Falone, S.3
Aimola, P.4
Giardinelli, A.5
Caserta, D.6
Marci, R.7
Pandolfi, A.8
Ragnelli, A.M.9
-
57
-
-
0036420161
-
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
-
Lee, H.C.; Yin, P.H.; Chi, C.W.; Wei, Y.H. Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J. Biomed. Sci. 2002, 9, 517-526.
-
(2002)
J. Biomed. Sci
, vol.9
, pp. 517-526
-
-
Lee, H.C.1
Yin, P.H.2
Chi, C.W.3
Wei, Y.H.4
-
58
-
-
0035028669
-
Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4, 977 BP-deleted mitochondrial DNA
-
Wei, Y.H.; Lee, C.F.; Lee, H.C.; Ma, Y.S.; Wang, C.W.; Lu, C.Y.; Pang, C.Y. Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4, 977 BP-deleted mitochondrial DNA. Ann. N. Y. Acad. Sci. 2001, 928, 97-112.
-
(2001)
Ann. N. Y. Acad. Sci
, vol.928
, pp. 97-112
-
-
Wei, Y.H.1
Lee, C.F.2
Lee, H.C.3
Ma, Y.S.4
Wang, C.W.5
Lu, C.Y.6
Pang, C.Y.7
-
59
-
-
0034214103
-
Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells
-
Lee, H.C.; Yin, P.H.; Lu, C.Y.; Chi, C.W.; Wei, Y.H. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem. J. 2000, 348, 425-432.
-
(2000)
Biochem. J
, vol.348
, pp. 425-432
-
-
Lee, H.C.1
Yin, P.H.2
Lu, C.Y.3
Chi, C.W.4
Wei, Y.H.5
-
60
-
-
0034668946
-
Mitochondria as all-round players of the calcium game
-
Rizzuto, R.; Bernardi, P.; Pozzan, T. Mitochondria as all-round players of the calcium game. J. Physiol. 2000, 529, 37-47.
-
(2000)
J. Physiol
, vol.529
, pp. 37-47
-
-
Rizzuto, R.1
Bernardi, P.2
Pozzan, T.3
-
61
-
-
46649120115
-
The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death
-
Rimessi, A.; Giorgi, C.; Pinton, P.; Rizzuto, R. The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death. Biochim. Biophys. Acta 2008, 1777, 808-816.
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 808-816
-
-
Rimessi, A.1
Giorgi, C.2
Pinton, P.3
Rizzuto, R.4
-
62
-
-
42049101823
-
2+ signaling, mitochondria and cell death
-
2+ signaling, mitochondria and cell death. Curr. Mol. Med. 2008, 8, 119-130.
-
(2008)
Curr. Mol. Med
, vol.8
, pp. 119-130
-
-
Giorgi, C.1
Romagnoli, A.2
Pinton, P.3
Rizzuto, R.4
-
63
-
-
69049098806
-
Structural and functional link between the mitochondrial network and the endoplasmic reticulum
-
Giorgi, C.; de Stefani, D.; Bononi, A.; Rizzuto, R.; Pinton, P. Structural and functional link between the mitochondrial network and the endoplasmic reticulum. Int. J. Biochem. Cell Biol. 2009, 41, 1817-1827.
-
(2009)
Int. J. Biochem. Cell Biol
, vol.41
, pp. 1817-1827
-
-
Giorgi, C.1
de Stefani, D.2
Bononi, A.3
Rizzuto, R.4
Pinton, P.5
-
64
-
-
43049115673
-
Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblasts
-
Guillery, O.; Malka, F.; Frachon, P.; Milea, D.; Rojo, M.; Lombes, A. Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblasts. Neuromuscul. Disord. 2008, 18, 319-330.
-
(2008)
Neuromuscul. Disord
, vol.18
, pp. 319-330
-
-
Guillery, O.1
Malka, F.2
Frachon, P.3
Milea, D.4
Rojo, M.5
Lombes, A.6
-
65
-
-
10644226829
-
Respiratory chain analysis of skin fibroblasts in mitochondrial disease
-
Cameron, J.M.; Levandovskiy, V.; MacKay, N.; Robinson, B.H. Respiratory chain analysis of skin fibroblasts in mitochondrial disease. Mitochondrion 2004, 4, 387-394.
-
(2004)
Mitochondrion
, vol.4
, pp. 387-394
-
-
Cameron, J.M.1
Levandovskiy, V.2
McKay, N.3
Robinson, B.H.4
-
66
-
-
0023918846
-
Cell culture studies on patients with mitochondrial diseases: Molecular defects in pyruvate dehydrogenase
-
Robinson, B.H. Cell culture studies on patients with mitochondrial diseases: Molecular defects in pyruvate dehydrogenase. J. Bioenerg. Biomembr. 1988, 20, 313-323.
-
(1988)
J. Bioenerg. Biomembr
, vol.20
, pp. 313-323
-
-
Robinson, B.H.1
-
67
-
-
0022487208
-
Respiratory chain defects in the mitochondria of cultured skin fibroblasts from three patients with lacticacidemia
-
Robinson, B.H.; Ward, J.; Goodyer, P.; Baudet, A. Respiratory chain defects in the mitochondria of cultured skin fibroblasts from three patients with lacticacidemia. J. Clin. Invest. 1986, 77, 1422-1427.
-
(1986)
J. Clin. Invest
, vol.77
, pp. 1422-1427
-
-
Robinson, B.H.1
Ward, J.2
Goodyer, P.3
Baudet, A.4
|