메뉴 건너뛰기




Volumn 6, Issue 6, 2012, Pages 719-727

Metabolic syndrome in youth: Current insights and novel serum biomarkers

Author keywords

adiponectin; FDF21; insulin resistance; metabolic syndrome; PEDF; pigment epithelium derived factor; RBP4

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR 21; GLUCOSE TRANSPORTER 4; INSULIN; PIGMENT EPITHELIUM DERIVED FACTOR; REACTIVE OXYGEN METABOLITE; RETINOL BINDING PROTEIN 4;

EID: 84870915680     PISSN: 17520363     EISSN: 17520371     Source Type: Journal    
DOI: 10.2217/bmm.12.85     Document Type: Review
Times cited : (10)

References (99)
  • 1
    • 0027512732 scopus 로고
    • Role of insulin resistance in human disease (syndrome X): An expanded definition
    • Reaven GM. Role of insulin resistance in human disease (syndrome X): An expanded definition. Ann. Rev. Med. 44, 121-131 (1993
    • (1993) Ann. Rev. Med , vol.44 , pp. 121-131
    • Reaven, G.M.1
  • 2
    • 2542548063 scopus 로고    scopus 로고
    • Obesity and the metabolic syndrome in children and adolescents
    • Weiss R, Dziura J, Burgert TS et al. Obesity and the metabolic syndrome in children and adolescents. N. Engl. J. Med. 350(23), 2362-2374 (2004
    • (2004) N. Engl. J. Med , vol.350 , Issue.23 , pp. 2362-2374
    • Weiss, R.1    Dziura, J.2    Burgert, T.S.3
  • 3
    • 45349094655 scopus 로고    scopus 로고
    • Relationship between metabolic syndrome definitions for children and adolescents and intima-media thickness
    • Reinehr T, Wunsch R, De Sousa G, Toschke AM. Relationship between metabolic syndrome definitions for children and adolescents and intima-media thickness. Atherosclerosis 199(1), 193-200 (2008
    • (2008) Atherosclerosis , vol.199 , Issue.1 , pp. 193-200
    • Reinehr, T.1    Wunsch, R.2    De Sousa, G.3    Toschke, Am.4
  • 4
    • 34250651656 scopus 로고    scopus 로고
    • The metabolic syndrome in children and adolescents
    • Zimmet P, Alberti G, Kaufman F et al. The metabolic syndrome in children and adolescents. Lancet 369(9579), 2059-2061 (2007
    • (2007) Lancet , vol.369 , Issue.9579 , pp. 2059-2061
    • Zimmet, P.1    Alberti, G.2    Kaufman, F.3
  • 5
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol. Rev. 75(3), 473-486 (1995
    • (1995) Physiol. Rev , vol.75 , Issue.3 , pp. 473-486
    • Reaven, G.M.1
  • 6
    • 21244444320 scopus 로고    scopus 로고
    • The 'obese insulin-sensitive' adolescent importance of adiponectin and lipid partitioning
    • Weiss R, Taksali SE, Dufour S et al. The 'obese insulin-sensitive' adolescent. importance of adiponectin and lipid partitioning. J. Clin. Endocrinol. Metab. 90(6), 3731-3737 (2005
    • (2005) J. Clin. Endocrinol. Metab , vol.90 , Issue.6 , pp. 3731-3737
    • Weiss, R.1    Taksali, S.E.2    Dufour, S.3
  • 7
    • 34548742845 scopus 로고    scopus 로고
    • Fat distribution and storage: How much, where, and how?
    • Weiss R. Fat distribution and storage: How much, where, and how? Eur. J. Endocrinol. 157(SUPPL1), S39-S45 (2007
    • (2007) Eur. J. Endocrinol , vol.157 , Issue.SUPPL. 1
    • Weiss, R.1
  • 8
    • 40749121780 scopus 로고    scopus 로고
    • High visceral and low abdominal subcutaneous fat stores in the obese adolescent A determinant of an adverse metabolic phenotype
    • Taksali SE, Caprio S, Dziura J et al. High visceral and low abdominal subcutaneous fat stores in the obese adolescent. A determinant of an adverse metabolic phenotype. Diabetes 57(2), 367-371 (2008
    • (2008) Diabetes , vol.57 , Issue.2 , pp. 367-371
    • Taksali, S.E.1    Caprio, S.2    Dziura, J.3
  • 9
    • 33745784213 scopus 로고    scopus 로고
    • Thematic review series: Patient-oriented research Free fatty acid metabolism in human obesity
    • Koutsari C, Jensen MD. Thematic review series: Patient-oriented research. Free fatty acid metabolism in human obesity. J. Lipid Res. 47(8), 1643-1650 (2006
    • (2006) J. Lipid Res , vol.47 , Issue.8 , pp. 1643-1650
    • Koutsari, C.1    Jensen, M.D.2
  • 10
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ. Res. 96(9), 939-949 (2005
    • (2005) Circ. Res , vol.96 , Issue.9 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 11
    • 80053608161 scopus 로고    scopus 로고
    • Metabolic syndrome in pediatrics: Old concepts revised, new concepts discussed
    • D'Adamo E, Santoro N, Caprio S. Metabolic syndrome in pediatrics: Old concepts revised, new concepts discussed. Pediatr. Clin. North Am. 58(5), 1241-1255, (2011
    • (2011) Pediatr. Clin. North Am. , vol.58 , Issue.5 , pp. 1241-1255
    • D'Adamo, E.1    Santoro, N.2    Caprio, S.3
  • 12
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 40(6), 1387-1395 (2004
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 13
    • 70350241227 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease in children: A follow-up study for up to 20 years
    • Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB, Angulo P. The natural history of nonalcoholic fatty liver disease in children: A follow-up study for up to 20 years. Gut 58(11), 1538-1544 (2009
    • (2009) Gut , vol.58 , Issue.11 , pp. 1538-1544
    • Feldstein, A.E.1    Charatcharoenwitthaya, P.2    Treeprasertsuk, S.3    Benson, J.T.4    Enders, F.B.5    Angulo, P.6
  • 14
    • 33751519769 scopus 로고    scopus 로고
    • Alanine aminotransferase levels and fatty liver in childhood obesity: Associations with insulin resistance, adiponectin, and visceral fat
    • Burgert TS, Taksali SE, Dziura J et al. Alanine aminotransferase levels and fatty liver in childhood obesity: Associations with insulin resistance, adiponectin, and visceral fat. J. Clin. Endocrinol. Metab. 91(11), 4287-4294 (2006
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , Issue.11 , pp. 4287-4294
    • Burgert, T.S.1    Taksali, S.E.2    Dziura, J.3
  • 15
    • 68949136755 scopus 로고    scopus 로고
    • Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link?
    • Cali AM, De Oliveira AM, Kim H et al. Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link? Hepatology 49(6), 1896-1903 (2009
    • (2009) Hepatology , vol.49 , Issue.6 , pp. 1896-1903
    • Cali, Am.1    De Oliveira, Am.2    Kim, H.3
  • 16
    • 77956643015 scopus 로고    scopus 로고
    • Ethnic differences in lipoprotein subclasses in obese adolescents: Importance of liver and intraabdominal fat accretion
    • D'Adamo E, Northrup V, Weiss R et al. Ethnic differences in lipoprotein subclasses in obese adolescents: Importance of liver and intraabdominal fat accretion. Am. J. Clin. Nutr. 92(3), 500-508 (2010
    • (2010) Am. J. Clin. Nutr , vol.92 , Issue.3 , pp. 500-508
    • D'Adamo, E.1    Northrup, V.2    Weiss, R.3
  • 17
    • 77958180000 scopus 로고    scopus 로고
    • Central role of fatty liver in the pathogenesis of insulin resistance in obese adolescents
    • D'Adamo E, Cali AM, Weiss R et al. Central role of fatty liver in the pathogenesis of insulin resistance in obese adolescents. Diabetes Care 33(8), 1817-1822 (2010
    • (2010) Diabetes Care , vol.33 , Issue.8 , pp. 1817-1822
    • D'Adamo, E.1    Cali, Am.2    Weiss, R.3
  • 18
    • 0141763847 scopus 로고    scopus 로고
    • Prediabetes in obese youth A syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning
    • Weiss R, Dufour S, Taksali SE et al. Prediabetes in obese youth. A syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning. Lancet 362(9388), 951-957 (2003
    • (2003) Lancet , vol.362 , Issue.9388 , pp. 951-957
    • Weiss, R.1    Dufour, S.2    Taksali, S.E.3
  • 19
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel VT, Shulman GI. Mechanisms for insulin resistance: Common threads and missing links. Cell 148(5), 852-871 (2012
    • (2012) Cell , vol.148 , Issue.5 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 20
    • 77953868236 scopus 로고    scopus 로고
    • Lipid-Induced insulin resistance: Unravelling the mechanism
    • Samuel VT, Petersen KF, Shulman GI. Lipid-Induced insulin resistance: Unravelling the mechanism. Lancet 375(9733), 2267-2277 (2010
    • (2010) Lancet , vol.375 , Issue.9733 , pp. 2267-2277
    • Samuel, V.T.1    Petersen, K.F.2    Shulman, G.I.3
  • 22
    • 84862330756 scopus 로고    scopus 로고
    • Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans
    • Bergman BC, Hunerdosse DM, Kerege A, Playdon MC, Perreault L. Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. Diabetologia 55(4), 1140-1150 (2012
    • (2012) Diabetologia , vol.55 , Issue.4 , pp. 1140-1150
    • Bergman, B.C.1    Hunerdosse, D.M.2    Kerege, A.3    Playdon, M.C.4    Perreault, L.5
  • 23
    • 40849092781 scopus 로고    scopus 로고
    • Mitochondrial energetics and insulin resistance
    • Civitarese AE, Ravussin E. Mitochondrial energetics and insulin resistance. Endocrinology 149(3), 950-954 (2008
    • (2008) Endocrinology , vol.149 , Issue.3 , pp. 950-954
    • Civitarese, A.E.1    Ravussin, E.2
  • 24
    • 78650665214 scopus 로고    scopus 로고
    • Phagocyte-like NADPH oxidase promotes cytokine-Induced mitochondrial dysfunction in pancreatic beta-cells: Evidence for regulation by Rac1
    • Subasinghe W, Syed I, Kowluru A. Phagocyte-like NADPH oxidase promotes cytokine-Induced mitochondrial dysfunction in pancreatic beta-cells: Evidence for regulation by Rac1. Am. J. Physiol. Regul. Integr. Comp. Physiol. 300(1), R12-R20 (2011
    • (2011) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.300 , Issue.1
    • Subasinghe, W.1    Syed, I.2    Kowluru, A.3
  • 25
    • 84857973646 scopus 로고    scopus 로고
    • Toward a unifying hypothesis of metabolic syndrome
    • Bremer AA, Mietus-Snyder M, Lustig RH. Toward a unifying hypothesis of metabolic syndrome. Pediatrics 129(3), 557-570 (2012
    • (2012) Pediatrics , vol.129 , Issue.3 , pp. 557-570
    • Bremer, A.A.1    Mietus-Snyder, M.2    Lustig, R.H.3
  • 26
    • 0037137285 scopus 로고    scopus 로고
    • Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: Nested case-control study
    • Brunner EJ, Hemingway H, Walker BR et al. Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: Nested case-control study. Circulation 106(21), 2659-2665 (2002
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2659-2665
    • Brunner, E.J.1    Hemingway, H.2    Walker, B.R.3
  • 27
    • 0035824440 scopus 로고    scopus 로고
    • A transgenic model of visceral obesity and the metabolic syndrome
    • Masuzaki H, Paterson J, Shinyama H et al. A transgenic model of visceral obesity and the metabolic syndrome. Science 294(5549), 2166-2170 (2001
    • (2001) Science , vol.294 , Issue.5549 , pp. 2166-2170
    • Masuzaki, H.1    Paterson, J.2    Shinyama, H.3
  • 28
    • 84870904243 scopus 로고    scopus 로고
    • 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors. Novel agents for the treatment of metabolic syndrome and obesity-related disorders?
    • doi:10.1016/j. metabol.2012.05.002 Epub ahead of print
    • Anagnostis P, Katsiki N, Adamidou F et al. 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors. Novel agents for the treatment of metabolic syndrome and obesity-related disorders? Metabolism doi:10.1016/j. metabol.2012.05.002 (2012) (Epub ahead of print
    • (2012) Metabolism
    • Anagnostis, P.1    Katsiki, N.2    Adamidou, F.3
  • 30
    • 80052361940 scopus 로고    scopus 로고
    • Metabolic syndrome: Links to social stress and socioeconomic status
    • Tamashiro KL. Metabolic syndrome: Links to social stress and socioeconomic status. Ann. NY Acad. Sci. 1231, 46-55 (2011
    • (2011) Ann. NY Acad. Sci , vol.1231 , pp. 46-55
    • Tamashiro, K.L.1
  • 31
    • 70449435656 scopus 로고    scopus 로고
    • Epidemiological evidence for the links between sleep, circadian rhythms and metabolism
    • Gangwisch JE. Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes. Rev. 10(SUPPL2), 37-45 (2009
    • (2009) Obes. Rev , vol.10 , Issue.SUPPL. 2 , pp. 37-45
    • Gangwisch, J.E.1
  • 32
    • 77649138576 scopus 로고    scopus 로고
    • Circadian rhythms and metabolic syndrome: From experimental genetics to human disease
    • Maury E, Ramsey KM, Bass J. Circadian rhythms and metabolic syndrome: From experimental genetics to human disease. Circ. Res. 106(3), 447-462 (2010
    • (2010) Circ. Res , vol.106 , Issue.3 , pp. 447-462
    • Maury, E.1    Ramsey, K.M.2    Bass, J.3
  • 33
    • 36348953149 scopus 로고    scopus 로고
    • Does short sleep duration favor abdominal adiposity in childreñInt
    • Chaput JP, Tremblay A. Does short sleep duration favor abdominal adiposity in childreñInt. J. Pediatr. Obes. 2(3), 188-191 (2007
    • (2007) J. Pediatr. Obes , vol.2 , Issue.3 , pp. 188-191
    • Chaput, J.P.1    Tremblay, A.2
  • 34
    • 0025772716 scopus 로고
    • PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity
    • Tombran-Tink J, Chader GG, Johnson LV. PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity. Exp. Eye Res. 53(3), 411-414 (1991
    • (1991) Exp. Eye Res , vol.53 , Issue.3 , pp. 411-414
    • Tombran-Tink, J.1    Chader, G.G.2    Johnson, L.V.3
  • 35
    • 67649446288 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor contributes to insulin resistance in obesity
    • Crowe S, Wu LE, Economou C et al. Pigment epithelium-derived factor contributes to insulin resistance in obesity. Cell Metab. 10(1), 40-47 (2009
    • (2009) Cell Metab , vol.10 , Issue.1 , pp. 40-47
    • Crowe, S.1    Wu, L.E.2    Economou, C.3
  • 36
    • 79958822242 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells
    • Famulla S, Lamers D, Hartwig S et al. Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells. Int. J. Obes. (Lond.) 35(6), 762-772 (2011
    • (2011) Int. J. Obes. (Lond , vol.35 , Issue.6 , pp. 762-772
    • Famulla, S.1    Lamers, D.2    Hartwig, S.3
  • 37
    • 70749083140 scopus 로고    scopus 로고
    • PEDF prevents reactive oxygen species generation and retinal endothelial cell damage at high glucose levels
    • Banumathi E, Sheikpranbabu S, Haribalaganesh R, Gurunathan S. PEDF prevents reactive oxygen species generation and retinal endothelial cell damage at high glucose levels. Exp. Eye Res. 90(1), 89-96 (2010
    • (2010) Exp. Eye Res , vol.90 , Issue.1 , pp. 89-96
    • Banumathi, E.1    Sheikpranbabu, S.2    Haribalaganesh, R.3    Gurunathan, S.4
  • 38
    • 55749098939 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein
    • Zhang SX, Wang JJ, Dashti A et al. Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein. J. Mol. Endocrinol. 41(3), 135-143 (2008
    • (2008) J. Mol. Endocrinol , vol.41 , Issue.3 , pp. 135-143
    • Zhang, S.X.1    Wang, J.J.2    Dashti, A.3
  • 39
    • 77953728438 scopus 로고    scopus 로고
    • Positive association of serum levels of pigment epithelium-derived factor with highsensitivity C-reactive protein in apparently healthy unmedicated subjects
    • Umei H, Yamagishi SI, Imaizumi T. Positive association of serum levels of pigment epithelium-derived factor with highsensitivity C-reactive protein in apparently healthy unmedicated subjects. J. Int. Med. Res. 38(2), 443-448 (2010
    • (2010) J. Int. Med. Res , vol.38 , Issue.2 , pp. 443-448
    • Umei, H.1    Yamagishi, S.I.2    Imaizumi, T.3
  • 40
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • Dawson DW, Volpert OV, Gillis P et al. Pigment epithelium-derived factor: A potent inhibitor of angiogenesis. Science 285(5425), 245-248 (1999
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3
  • 41
    • 78049490696 scopus 로고    scopus 로고
    • Plasma level of pigment epithelium-derived factor is independently associated with the development of the metabolic syndrome in Chinese men A 10-year prospective study
    • Chen C, Tso AW, Law LS et al. Plasma level of pigment epithelium-derived factor is independently associated with the development of the metabolic syndrome in Chinese men. A 10-year prospective study. J. Clin. Endocrinol. Metab. 95(11), 5074-5081 (2010
    • (2010) J. Clin. Endocrinol. Metab , vol.95 , Issue.11 , pp. 5074-5081
    • Chen, C.1    Tso, A.W.2    Law, L.S.3
  • 42
    • 75749105438 scopus 로고    scopus 로고
    • Pigment epitheliumderived factor as a new marker of metabolic syndrome in Caucasian population
    • Stejskal D, Karpisek M, Svestak M, Hejduk P, Sporova L, Kotolova H. Pigment epitheliumderived factor as a new marker of metabolic syndrome in Caucasian population. J. Clin. Lab. Anal. 24(1), 17-19 (2010
    • (2010) J. Clin. Lab. Anal , vol.24 , Issue.1 , pp. 17-19
    • Stejskal, D.1    Karpisek, M.2    Svestak, M.3    Hejduk, P.4    Sporova, L.5    Kotolova, H.6
  • 43
    • 33646189532 scopus 로고    scopus 로고
    • Elevated serum levels of pigment epithelium-derived factor in the metabolic syndrome
    • Yamagishi S, Adachi H, Abe A et al. Elevated serum levels of pigment epithelium-derived factor in the metabolic syndrome. J. Clin. Endocrinol. Metab. 91(6), 2447-2450 (2006
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , Issue.6 , pp. 2447-2450
    • Yamagishi, S.1    Adachi, H.2    Abe, A.3
  • 44
    • 84878893936 scopus 로고    scopus 로고
    • Insulin resistance is associated with elevated serum pigment epithelium-derived factor (PEDF) levels in morbidly obese patients
    • doi:10.1007/s00592-012-0397-y Epub ahead of print
    • Gattu AK, Birkenfeld AL, Jornayvaz F et al. Insulin resistance is associated with elevated serum pigment epithelium-derived factor (PEDF) levels in morbidly obese patients. Acta Diabetol. doi:10.1007/s00592-012-0397-y (2012) (Epub ahead of print
    • (2012) Acta Diabetol
    • Gattu, A.K.1    Birkenfeld, A.L.2    Jornayvaz, F.3
  • 45
    • 33845989501 scopus 로고    scopus 로고
    • Identification of a lipase-linked cell membrane receptor for pigment epitheliumderived factor
    • Notari L, Baladron V, Aroca-Aguilar JD et al. Identification of a lipase-linked cell membrane receptor for pigment epitheliumderived factor. J. Biol. Chem. 281(49), 38022-38037 (2006
    • (2006) J. Biol. Chem , vol.281 , Issue.49 , pp. 38022-38037
    • Notari, L.1    Baladron, V.2    Aroca-Aguilar, J.D.3
  • 46
    • 77951241740 scopus 로고    scopus 로고
    • Pigment epitheliumderived factor binds to cell-surface F1-ATP synthase
    • Notari L, Arakaki N, Mueller D, Meier S, Amaral J, Becerra SP. Pigment epitheliumderived factor binds to cell-surface F1-ATP synthase. FEBS J. 277(9), 2192-2205 (2010
    • (2010) FEBS J. , vol.277 , Issue.9 , pp. 2192-2205
    • Notari, L.1    Arakaki, N.2    Mueller, D.3    Meier, S.4    Amaral, J.5    Becerra, S.P.6
  • 47
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and Type 2 diabetes
    • Yang Q, Graham TE, Mody N et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and Type 2 diabetes. Nature 436(7049), 356-362 (2005
    • (2005) Nature , vol.436 , Issue.7049 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 48
    • 0035825643 scopus 로고    scopus 로고
    • Adiposeselective targeting of the GLUT4 gene impairs insulin action in muscle and liver
    • Abel ED, Peroni O, Kim JK et al. Adiposeselective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 409(6821), 729-733 (2001
    • (2001) Nature , vol.409 , Issue.6821 , pp. 729-733
    • Abel, E.D.1    Peroni, O.2    Kim, J.K.3
  • 49
    • 33745095399 scopus 로고    scopus 로고
    • Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
    • Graham TE, Yang Q, Bluher M et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N. Engl. J. Med. 354(24), 2552-2563 (2006
    • (2006) N. Engl. J. Med , vol.354 , Issue.24 , pp. 2552-2563
    • Graham, T.E.1    Yang, Q.2    Bluher, M.3
  • 50
    • 33847657606 scopus 로고    scopus 로고
    • Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and Type 2 diabetes: Response to
    • Cho et al
    • Gavi S, Qurashi S, Melendez MM, Mynarcik DC, McNurlan MA, Gelato MC. Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and Type 2 diabetes: Response to Cho et al. Diabetes Care 30(3), e7; author reply e8 (2007
    • (2007) Diabetes Care , vol.30 , Issue.3
    • Gavi, S.1    Qurashi, S.2    Melendez, M.M.3    Mynarcik, D.C.4    McNurlan, M.A.5    Gelato, M.C.6
  • 51
    • 33845479911 scopus 로고    scopus 로고
    • Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and Type 2 diabetes
    • Cho YM, Youn BS, Lee H et al. Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and Type 2 diabetes. Diabetes Care 29(11), 2457-2461 (2006
    • (2006) Diabetes Care , vol.29 , Issue.11 , pp. 2457-2461
    • Cho, Y.M.1    Youn, B.S.2    Lee, H.3
  • 52
    • 34249860936 scopus 로고    scopus 로고
    • Retinolbinding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without Type 2 diabetes
    • Gavi S, Stuart LM, Kelly P et al. Retinolbinding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without Type 2 diabetes. J. Clin. Endocrinol. Metab. 92(5), 1886-1890 (2007
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , Issue.5 , pp. 1886-1890
    • Gavi, S.1    Stuart, L.M.2    Kelly, P.3
  • 53
    • 34547787736 scopus 로고    scopus 로고
    • Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without Type 2 diabetes
    • Jia W, Wu H, Bao Y et al. Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without Type 2 diabetes. J. Clin. Endocrinol. Metab. 92(8), 3224-3229 (2007
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , Issue.8 , pp. 3224-3229
    • Jia, W.1    Wu, H.2    Bao, Y.3
  • 54
    • 35548929348 scopus 로고    scopus 로고
    • Visceral adiposity is associated with serum retinol binding protein-4 levels in healthy women
    • Lee JW, Im JA, Lee HR, Shim JY, Youn BS, Lee DC. Visceral adiposity is associated with serum retinol binding protein-4 levels in healthy women. Obesity (Silver Spring) 15(9), 2225-2232 (2007
    • (2007) Obesity (Silver Spring , vol.15 , Issue.9 , pp. 2225-2232
    • Lee, J.W.1    Im, J.A.2    Lee, H.R.3    Shim, J.Y.4    Youn, B.S.5    Lee, D.C.6
  • 55
    • 77950188623 scopus 로고    scopus 로고
    • Retinol-binding protein 4 (RBP4) protein expression is increased in omental adipose tissue of severely obese patients
    • Kelly KR, Kashyap SR, O'Leary VB, Major J, Schauer PR, Kirwan JP. Retinol-binding protein 4 (RBP4) protein expression is increased in omental adipose tissue of severely obese patients. Obesity (Silver Spring) 18(4), 663-666 (2010
    • (2010) Obesity (Silver Spring , vol.18 , Issue.4 , pp. 663-666
    • Kelly, K.R.1    Kashyap, S.R.2    O'Leary, V.B.3    Major, J.4    Schauer, P.R.5    Kirwan, J.P.6
  • 56
    • 34347233419 scopus 로고    scopus 로고
    • Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-Abdominal fat mass
    • Kloting N, Graham TE, Berndt J et al. Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-Abdominal fat mass. Cell Metab. 6(1), 79-87 (2007
    • (2007) Cell Metab , vol.6 , Issue.1 , pp. 79-87
    • Kloting, N.1    Graham, T.E.2    Berndt, J.3
  • 57
    • 33750851422 scopus 로고    scopus 로고
    • Retinol-binding protein 4 in human obesity
    • Janke J, Engeli S, Boschmann M et al. Retinol-binding protein 4 in human obesity. Diabetes 55(10), 2805-2810 (2006
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2805-2810
    • Janke, J.1    Engeli, S.2    Boschmann, M.3
  • 58
    • 55049118712 scopus 로고    scopus 로고
    • Abdominal visceral fat reduction is associated with favorable changes of serum retinol binding protein-4 in nondiabetic subjects
    • Lee JW, Lee HR, Shim JY, Im JA, Lee DC. Abdominal visceral fat reduction is associated with favorable changes of serum retinol binding protein-4 in nondiabetic subjects. Endocr. J. 55(5), 811-818 (2008
    • (2008) Endocr. J. , vol.55 , Issue.5 , pp. 811-818
    • Lee, J.W.1    Lee, H.R.2    Shim, J.Y.3    Im, J.A.4    Lee, D.C.5
  • 59
    • 34347252326 scopus 로고    scopus 로고
    • Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-Induced changes in insulin sensitivity
    • Vitkova M, Klimcakova E, Kovacikova M et al. Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-Induced changes in insulin sensitivity. J. Clin. Endocrinol. Metab. 92(6), 2330-2335 (2007
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , Issue.6 , pp. 2330-2335
    • Vitkova, M.1    Klimcakova, E.2    Kovacikova, M.3
  • 60
    • 77955374005 scopus 로고    scopus 로고
    • Case-control analysis of SNPs in GLUT4 RBP4 and STRA6: Association of SNPs in STRA6 with Type 2 diabetes in a South Indian population
    • Nair AK, Sugunan D, Kumar H, Anilkumar G. Case-control analysis of SNPs in GLUT4, RBP4 and STRA6: Association of SNPs in STRA6 with Type 2 diabetes in a South Indian population. Plos One 5(7), e11444 (2010
    • (2010) Plos One , vol.5 , Issue.7
    • Nair, A.K.1    Sugunan, D.2    Kumar, H.3    Anilkumar, G.4
  • 61
    • 65649149323 scopus 로고    scopus 로고
    • Visceral obesity is associated with the metabolic syndrome and elevated plasma retinol binding protein-4 level in obstructive sleep apnea syndrome
    • Makino S, Fujiwara M, Suzukawa K et al. Visceral obesity is associated with the metabolic syndrome and elevated plasma retinol binding protein-4 level in obstructive sleep apnea syndrome. Horm. Metab. Res. 41(3), 221-226 (2009
    • (2009) Horm. Metab. Res , vol.41 , Issue.3 , pp. 221-226
    • Makino, S.1    Fujiwara, M.2    Suzukawa, K.3
  • 62
    • 77950188054 scopus 로고    scopus 로고
    • Combined impact of adiponectin and retinol-binding protein 4 on metabolic syndrome in elderly people the korean longitudinal study on health and aging
    • Lim S, Yoon JW, Choi SH et al. Combined impact of adiponectin and retinol-binding protein 4 on metabolic syndrome in elderly people. The Korean Longitudinal Study on Health and Aging. Obesity (Silver Spring) 18(4), 826-832 (2010
    • (2010) Obesity (Silver Spring , vol.18 , Issue.4 , pp. 826-832
    • Lim, S.1    Yoon, J.W.2    Choi, S.H.3
  • 63
    • 67650552639 scopus 로고    scopus 로고
    • RBP4 variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in chinese hans
    • Wu Y, Li H, Loos RJ et al. RBP4 variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in Chinese Hans. J. Lipid Res. 50(7), 1479-1486 (2009
    • (2009) J. Lipid Res , vol.50 , Issue.7 , pp. 1479-1486
    • Wu, Y.1    Li, H.2    Loos, R.J.3
  • 64
    • 78649732399 scopus 로고    scopus 로고
    • Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness
    • Bobbert T, Raila J, Schwarz F et al. Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness. Atherosclerosis 213(2), 549-551 (2010
    • (2010) Atherosclerosis , vol.213 , Issue.2 , pp. 549-551
    • Bobbert, T.1    Raila, J.2    Schwarz, F.3
  • 65
    • 77949435819 scopus 로고    scopus 로고
    • Elevation of plasma retinol-binding protein 4 and reduction of plasma adiponectin in subjects with cerebral infarction
    • Sasaki M, Otani T, Kawakami M, Ishikawa SE. Elevation of plasma retinol-binding protein 4 and reduction of plasma adiponectin in subjects with cerebral infarction. Metabolism 59(4), 527-532 (2010
    • (2010) Metabolism , vol.59 , Issue.4 , pp. 527-532
    • Sasaki, M.1    Otani, T.2    Kawakami, M.3    Ishikawa, S.E.4
  • 66
    • 68949205087 scopus 로고    scopus 로고
    • Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly
    • Ingelsson E, Sundstrom J, Melhus H et al. Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly. Atherosclerosis 206(1), 239-244 (2009
    • (2009) Atherosclerosis , vol.206 , Issue.1 , pp. 239-244
    • Ingelsson, E.1    Sundstrom, J.2    Melhus, H.3
  • 67
    • 58149394428 scopus 로고    scopus 로고
    • Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women
    • Mallat Z, Simon T, Benessiano J et al. Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women. J. Clin. Endocrinol. Metab. 94(1), 255-260 (2009
    • (2009) J. Clin. Endocrinol. Metab , vol.94 , Issue.1 , pp. 255-260
    • Mallat, Z.1    Simon, T.2    Benessiano, J.3
  • 68
    • 70350303619 scopus 로고    scopus 로고
    • Variations of retinol binding protein 4 levels are not associated with changes in insulin resistance during puberty
    • Santoro N, Perrone L, Cirillo G et al. Variations of retinol binding protein 4 levels are not associated with changes in insulin resistance during puberty. J. Endocrinol. Invest. 32(5), 411-414 (2009
    • (2009) J. Endocrinol. Invest , vol.32 , Issue.5 , pp. 411-414
    • Santoro, N.1    Perrone, L.2    Cirillo, G.3
  • 69
    • 35948988483 scopus 로고    scopus 로고
    • Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children
    • Aeberli I, Biebinger R, Lehmann R, L'allemand D, Spinas GA, Zimmermann MB. Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children. J. Clin. Endocrinol. Metab. 92(11), 4359-4365 (2007
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , Issue.11 , pp. 4359-4365
    • Aeberli, I.1    Biebinger, R.2    Lehmann, R.3    L'Allemand, D.4    Spinas, G.A.5    Zimmermann, M.B.6
  • 70
    • 34547696758 scopus 로고    scopus 로고
    • Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with Type 2 diabetes or coronary artery disease
    • Von Eynatten M, Lepper PM, Liu D et al. Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with Type 2 diabetes or coronary artery disease. Diabetologia 50(9), 1930-1937 (2007
    • (2007) Diabetologia , vol.50 , Issue.9 , pp. 1930-1937
    • Von Eynatten, M.1    Lepper, P.M.2    Liu, D.3
  • 71
    • 65649097715 scopus 로고    scopus 로고
    • Retinol-binding protein 4 is associated with impaired glucose tolerance but not with whole body or hepatic insulin resistance in Mexican Americans
    • Chavez AO, Coletta DK, Kamath S et al. Retinol-binding protein 4 is associated with impaired glucose tolerance but not with whole body or hepatic insulin resistance in Mexican Americans. Am. J. Physiol. Endocrinol. Metab. 296(4), E758-E764 (2009
    • (2009) Am. J. Physiol. Endocrinol. Metab , vol.296 , Issue.4
    • Chavez, A.O.1    Coletta, D.K.2    Kamath, S.3
  • 72
    • 34247565954 scopus 로고    scopus 로고
    • Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
    • Goetz R, Beenken A, Ibrahimi OA et al. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol. Cell. Biol. 27(9), 3417-3428 (2007
    • (2007) Mol. Cell. Biol , vol.27 , Issue.9 , pp. 3417-3428
    • Goetz, R.1    Beenken, A.2    Ibrahimi, O.A.3
  • 73
    • 34848869695 scopus 로고    scopus 로고
    • Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
    • Kurosu H, Choi M, Ogawa Y et al. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J. Biol. Chem. 282(37), 26687-26695 (2007
    • (2007) J. Biol. Chem , vol.282 , Issue.37 , pp. 26687-26695
    • Kurosu, H.1    Choi, M.2    Ogawa, Y.3
  • 74
    • 57849155278 scopus 로고    scopus 로고
    • FGF21 N- and C-Termini play different roles in receptor interaction and activation
    • Yie J, Hecht R, Patel J et al. FGF21 N- And C-Termini play different roles in receptor interaction and activation. FEBS Lett. 583(1), 19-24 (2009
    • (2009) FEBS Lett , vol.583 , Issue.1 , pp. 19-24
    • Yie, J.1    Hecht, R.2    Patel, J.3
  • 75
    • 39149091423 scopus 로고    scopus 로고
    • FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho
    • Kharitonenkov A, Dunbar JD, Bina HA et al. FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho. J. Cell. Physiol. 215(1), 1-7 (2008
    • (2008) J. Cell. Physiol , vol.215 , Issue.1 , pp. 1-7
    • Kharitonenkov, A.1    Dunbar, J.D.2    Bina, H.A.3
  • 76
    • 77954277205 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats
    • Sarruf DA, Thaler JP, Morton GJ et al. Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. Diabetes 59(7), 1817-1824 (2010
    • (2010) Diabetes , vol.59 , Issue.7 , pp. 1817-1824
    • Sarruf, D.A.1    Thaler, J.P.2    Morton, G.J.3
  • 77
    • 48349127924 scopus 로고    scopus 로고
    • The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man
    • Galman C, Lundasen T, Kharitonenkov A et al. The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man. Cell Metab. 8(2), 169-174 (2008
    • (2008) Cell Metab , vol.8 , Issue.2 , pp. 169-174
    • Galman, C.1    Lundasen, T.2    Kharitonenkov, A.3
  • 78
    • 34249686631 scopus 로고    scopus 로고
    • Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21
    • Inagaki T, Dutchak P, Zhao G et al. Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metab. 5(6), 415-425 (2007
    • (2007) Cell Metab , vol.5 , Issue.6 , pp. 415-425
    • Inagaki, T.1    Dutchak, P.2    Zhao, G.3
  • 79
    • 71949094496 scopus 로고    scopus 로고
    • Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: Striking effects on fibroblast growth factor-21 induction
    • Sanchez J, Palou A, Pico C. Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: Striking effects on fibroblast growth factor-21 induction. Endocrinology 150(12), 5341-5350 (2009
    • (2009) Endocrinology , vol.150 , Issue.12 , pp. 5341-5350
    • Sanchez, J.1    Palou, A.2    Pico, C.3
  • 80
    • 79953217026 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis
    • Domouzoglou EM, Maratos-Flier E. Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis. Am. J. Clin. Nutr. 93(4), 901S-905S (2011
    • (2011) Am. J. Clin. Nutr , vol.93 , Issue.4
    • Domouzoglou, E.M.1    Maratos-Flier, E.2
  • 81
    • 0033515761 scopus 로고    scopus 로고
    • Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
    • Arita Y, Kihara S, Ouchi N et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257(1), 79-83 (1999
    • (1999) Biochem. Biophys. Res. Commun , vol.257 , Issue.1 , pp. 79-83
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 82
    • 0037312826 scopus 로고    scopus 로고
    • Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism
    • Tschritter O, Fritsche A, Thamer C et al. Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes 52(2), 239-243 (2003
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 239-243
    • Tschritter, O.1    Fritsche, A.2    Thamer, C.3
  • 83
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and Type 2 diabetes Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S et al. Hypoadiponectinemia in obesity and Type 2 diabetes. Close association with insulin resistance and hyperinsulinemia. J. Clin. Endocrinol. Metab. 86(5), 1930-1935 (2001
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , Issue.5 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3
  • 84
    • 1642467862 scopus 로고    scopus 로고
    • Decreased serum levels of adiponectin are a risk factor for the progression to Type 2 diabetes in the Japanese population: The Funagata study
    • Daimon M, Oizumi T, Saitoh T et al. Decreased serum levels of adiponectin are a risk factor for the progression to Type 2 diabetes in the Japanese population: The Funagata study. Diabetes Care 26(7), 2015-2020 (2003
    • (2003) Diabetes Care , vol.26 , Issue.7 , pp. 2015-2020
    • Daimon, M.1    Oizumi, T.2    Saitoh, T.3
  • 85
    • 0037031088 scopus 로고    scopus 로고
    • Adiponectin and development of Type 2 diabetes in the Pima Indian population
    • Lindsay RS, Funahashi T, Hanson RL et al. Adiponectin and development of Type 2 diabetes in the Pima Indian population. Lancet 360(9326), 57-58 (2002
    • (2002) Lancet , vol.360 , Issue.9326 , pp. 57-58
    • Lindsay, R.S.1    Funahashi, T.2    Hanson, R.L.3
  • 86
    • 0037452139 scopus 로고    scopus 로고
    • Adiponectin and protection against Type 2 diabetes mellitus
    • Spranger J, Kroke A, Mohlig M et al. Adiponectin and protection against Type 2 diabetes mellitus. Lancet 361(9353), 226-228 (2003
    • (2003) Lancet , vol.361 , Issue.9353 , pp. 226-228
    • Spranger, J.1    Kroke, A.2    Mohlig, M.3
  • 88
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J. Clin. Invest. 108(12), 1875-1881 (2001
    • (2001) J. Clin. Invest , vol.108 , Issue.12 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 89
    • 0035957040 scopus 로고    scopus 로고
    • Adipocytederived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocytederived macrophages
    • Ouchi N, Kihara S, Arita Y et al. Adipocytederived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocytederived macrophages. Circulation 103(8), 1057-1063 (2001
    • (2001) Circulation , vol.103 , Issue.8 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3
  • 90
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Waki H et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7(8), 941-946 (2001
    • (2001) Nat. Med , vol.7 , Issue.8 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 91
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-Acid oxidation by activating AMP activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y et al. Adiponectin stimulates glucose utilization and fatty-Acid oxidation by activating AMP activated protein kinase. Nat. Med. 8(11), 1288-1295 (2002
    • (2002) Nat. Med , vol.8 , Issue.11 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 92
    • 0037983775 scopus 로고    scopus 로고
    • Involvement of AMP-Activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes
    • Wu X, Motoshima H, Mahadev K, Stalker TJ, Scalia R, Goldstein BJ. Involvement of AMP-Activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes 52(6), 1355-1363 (2003
    • (2003) Diabetes , vol.52 , Issue.6 , pp. 1355-1363
    • Wu, X.1    Motoshima, H.2    Mahadev, K.3    Stalker, T.J.4    Scalia, R.5    Goldstein, B.J.6
  • 93
    • 33644664433 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: Comparison of activation of PPARalpha PPARgamma, and their combination
    • Tsuchida A, Yamauchi T, Takekawa S et al. Peroxisome proliferator- Activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: Comparison of activation of PPARalpha, PPARgamma, and their combination. Diabetes 54(12), 3358-3370 (2005
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3358-3370
    • Tsuchida, A.1    Yamauchi, T.2    Takekawa, S.3
  • 94
    • 33646346627 scopus 로고    scopus 로고
    • Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferatoractivated receptor gamma agonists
    • Nawrocki AR, Rajala MW, Tomas E et al. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferatoractivated receptor gamma agonists. J. Biol. Chem. 281(5), 2654-2660 (2006
    • (2006) J. Biol. Chem , vol.281 , Issue.5 , pp. 2654-2660
    • Nawrocki, A.R.1    Rajala, M.W.2    Tomas, E.3
  • 95
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423(6941), 762-769 (2003
    • (2003) Nature , vol.423 , Issue.6941 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3
  • 96
    • 34347255023 scopus 로고    scopus 로고
    • Adiponectin stimulates AMP-Activated protein kinase in the hypothalamus and increases food intake
    • Kubota N, Yano W, Kubota T et al. Adiponectin stimulates AMP-Activated protein kinase in the hypothalamus and increases food intake. Cell Metab. 6(1), 55-68 (2007
    • (2007) Cell Metab , vol.6 , Issue.1 , pp. 55-68
    • Kubota, N.1    Yano, W.2    Kubota, T.3
  • 97
    • 80052096595 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
    • Lamers D, Famulla S, Wronkowitz N et al. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 60(7), 1917-1925 (2011
    • (2011) Diabetes , vol.60 , Issue.7 , pp. 1917-1925
    • Lamers, D.1    Famulla, S.2    Wronkowitz, N.3
  • 98
    • 85027940419 scopus 로고    scopus 로고
    • Lipidomics is providing new insight into the metabolic syndrome and its sequelae
    • Meikle PJ, Christopher MJ. Lipidomics is providing new insight into the metabolic syndrome and its sequelae. Curr. Opin. Lipidol. 22(3), 210-215 (2011
    • (2011) Curr. Opin. Lipidol , vol.22 , Issue.3 , pp. 210-215
    • Meikle, P.J.1    Christopher, M.J.2
  • 99
    • 33751544793 scopus 로고    scopus 로고
    • Insulin gene variable number of tandem repeats (INS VNTR) genotype and metabolic syndrome in childhood obesity
    • Santoro N, Cirillo G, Amato A et al. Insulin gene variable number of tandem repeats (INS VNTR) genotype and metabolic syndrome in childhood obesity. J. Clin. Endocrinol. Metab. 91(11), 4641-4644 (2006
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , Issue.11 , pp. 4641-4644
    • Santoro, N.1    Cirillo, G.2    Amato, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.