Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells

International Journal of Obesity

Volumn 35, Issue 6, 2011, Pages 762-772

  Famulla, S ^a   Lamers, D ^a   Hartwig, S ^a   Passlack, W ^a   Horrighs, A ^a   Cramer, A ^a   Lehr, S ^a   Sell, H ^a   Eckel, J ^a  

^a LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

Author keywords

adipocytes; insulin resistance; PEDF; skeletal muscle cells; smooth muscle cells

Indexed keywords

ADIPONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGE; MUSCLE CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SMOOTH MUSCLE;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; AUTOCRINE COMMUNICATION; EYE PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INSULIN RESISTANCE; MALE; MICE; MUSCLE CELLS; MYOCYTES, SMOOTH MUSCLE; NERVE GROWTH FACTORS; NF-KAPPA B; OBESITY; PROTO-ONCOGENE PROTEINS C-AKT; SERPINS; UP-REGULATION;

MAMMALIA; MUS;

EID: 79958822242     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2010.212     Document Type: Article

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