-
1
-
-
33845890639
-
It's a GPCR world
-
Filmore D (2004) It's a GPCR world. Modern Drug Discovery 7(11):24-28.
-
(2004)
Modern Drug Discovery
, vol.7
, Issue.11
, pp. 24-28
-
-
Filmore, D.1
-
2
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
DOI 10.1126/science.289.5480.739
-
Palczewski K, et al. (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289(5480):739-745. (Pubitemid 30650186)
-
(2000)
Science
, vol.289
, Issue.5480
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le, T.I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
3
-
-
36448995359
-
2-adrenergic G protein-coupled receptor
-
DOI 10.1126/science.1150577
-
Cherezov V, et al. (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 318(5854):1258-1265. (Pubitemid 350172884)
-
(2007)
Science
, vol.318
, Issue.5854
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.F.4
Foon, S.T.5
Kobilka, T.S.6
Choi, H.-J.7
Kuhn, P.8
Weis, W.I.9
Kobilka, B.K.10
Stevens, R.C.11
-
4
-
-
47949129742
-
Structure of a beta1-adrenergic G-protein-coupled receptor
-
Warne T, et al. (2008) Structure of a beta1-adrenergic G-protein-coupled receptor. Nature 454(7203):486-491.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 486-491
-
-
Warne, T.1
-
5
-
-
56749103466
-
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
-
Jaakola VP, et al. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 322(5905):1211-1217.
-
(2008)
Science
, vol.322
, Issue.5905
, pp. 1211-1217
-
-
Jaakola, V.P.1
-
6
-
-
78449305788
-
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist
-
Chien EY, et al. (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330(6007):1091-1095.
-
(2010)
Science
, vol.330
, Issue.6007
, pp. 1091-1095
-
-
Chien, E.Y.1
-
7
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
Wu B, et al. (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330(6007):1066-1071.
-
(2010)
Science
, vol.330
, Issue.6007
, pp. 1066-1071
-
-
Wu, B.1
-
8
-
-
79960070651
-
Structure of the human histamine H1 receptor complex with doxepin
-
Shimamura T, et al. (2011) Structure of the human histamine H1 receptor complex with doxepin. Nature 475(7354):65-70.
-
(2011)
Nature
, vol.475
, Issue.7354
, pp. 65-70
-
-
Shimamura, T.1
-
9
-
-
84862777405
-
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
-
Haga K, et al. (2012) Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature 482(7386):547-551.
-
(2012)
Nature
, vol.482
, Issue.7386
, pp. 547-551
-
-
Haga, K.1
-
10
-
-
84863115467
-
Structure and dynamics of the M3 muscarinic acetylcholine receptor
-
Kruse AC, et al. (2012) Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature 482(7386):552-556.
-
(2012)
Nature
, vol.482
, Issue.7386
, pp. 552-556
-
-
Kruse, A.C.1
-
11
-
-
84857254248
-
Crystal structure of a lipid G protein-coupled receptor
-
Hanson MA, et al. (2012) Crystal structure of a lipid G protein-coupled receptor. Science 335(6070):851-855.
-
(2012)
Science
, vol.335
, Issue.6070
, pp. 851-855
-
-
Hanson, M.A.1
-
12
-
-
42149181885
-
Structural diversity of G protein-coupled receptors and significance for drug discovery
-
Lagerström MC, Schiöth HB (2008) Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov 7(4):339-357.
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.4
, pp. 339-357
-
-
Lagerström, M.C.1
Schiöth, H.B.2
-
13
-
-
84862777742
-
Structure of the human κ-opioid receptor in complex with JDTic
-
Wu HX, et al. (2012) Structure of the human κ-opioid receptor in complex with JDTic. Nature 485(7398):327-332.
-
(2012)
Nature
, vol.485
, Issue.7398
, pp. 327-332
-
-
Wu, H.X.1
-
14
-
-
84861096654
-
Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
-
Manglik A, et al. (2012) Crystal structure of the μ-opioid receptor bound to a morphinan antagonist. Nature 485(7398):321-326.
-
(2012)
Nature
, vol.485
, Issue.7398
, pp. 321-326
-
-
Manglik, A.1
-
15
-
-
84861075468
-
Structure of the δ-opioid receptor bound to naltrindole
-
Granier S, et al. (2012) Structure of the δ-opioid receptor bound to naltrindole. Nature 485(7398):400-404.
-
(2012)
Nature
, vol.485
, Issue.7398
, pp. 400-404
-
-
Granier, S.1
-
16
-
-
84861019261
-
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
-
Thompson AA, et al. (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 485(7398):395-399.
-
(2012)
Nature
, vol.485
, Issue.7398
, pp. 395-399
-
-
Thompson, A.A.1
-
17
-
-
67149136711
-
Passing the baton in class B GPCRs: Peptide hormone activation via helix induction?
-
Parthier C, Reedtz-Runge S, Rudolph R, Stubbs MT (2009) Passing the baton in class B GPCRs: Peptide hormone activation via helix induction? Trends Biochem Sci 34(6):303-310.
-
(2009)
Trends Biochem Sci
, vol.34
, Issue.6
, pp. 303-310
-
-
Parthier, C.1
Reedtz-Runge, S.2
Rudolph, R.3
Stubbs, M.T.4
-
18
-
-
46149098623
-
Class-B GPCR activation: Is ligand helix-capping the key?
-
Neumann JM, et al. (2008) Class-B GPCR activation: Is ligand helix-capping the key? Trends Biochem Sci 33(7):314-319.
-
(2008)
Trends Biochem Sci
, vol.33
, Issue.7
, pp. 314-319
-
-
Neumann, J.M.1
-
19
-
-
84863274700
-
Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
-
Pal K, Melcher K, Xu HE (2012) Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors. Acta Pharmacol Sin 33(3):300-311.
-
(2012)
Acta Pharmacol Sin
, vol.33
, Issue.3
, pp. 300-311
-
-
Pal, K.1
Melcher, K.2
Xu, H.E.3
-
20
-
-
0022389280
-
Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets
-
DOI 10.1007/BF00291980
-
Schmidt WE, Siegel EG, Creutzfeldt W (1985) Glucagon-like peptide-1 but not glucagon- like peptide-2 stimulates insulin release from isolated rat pancreatic islets. Diabetologia 28(9):704-707. (Pubitemid 16226411)
-
(1985)
Diabetologia
, vol.28
, Issue.9
, pp. 704-707
-
-
Schmidt, W.E.1
Siegel, E.G.2
Creutzfeldt, W.3
-
21
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer TJ, Habener JF (1999) The glucagon-like peptides. Endocr Rev 20(6):876-913. (Pubitemid 30647076)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.6
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
22
-
-
0029118049
-
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
-
Kieffer TJ, McIntosh CH, Pederson RA (1995) Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology 136(8):3585-3596.
-
(1995)
Endocrinology
, vol.136
, Issue.8
, pp. 3585-3596
-
-
Kieffer, T.J.1
McIntosh, C.H.2
Pederson, R.A.3
-
23
-
-
0027215348
-
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
Mentlein R, Gallwitz B, Schmidt WE (1993) Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem 214(3):829-835. (Pubitemid 23188160)
-
(1993)
European Journal of Biochemistry
, vol.214
, Issue.3
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
24
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, Singh G, Raufman JP (1992) Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 267(11):7402-7405.
-
(1992)
J Biol Chem
, vol.267
, Issue.11
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
25
-
-
0035340019
-
Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
-
DOI 10.1053/meta.2001.22519
-
Parkes DG, Pittner R, Jodka C, Smith P, Young A (2001) Insulinotropic actions of exendin- 4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism 50(5):583-589. (Pubitemid 32433049)
-
(2001)
Metabolism: Clinical and Experimental
, vol.50
, Issue.5
, pp. 583-589
-
-
Parkes, D.G.1
Pittner, R.2
Jodka, C.3
Smith, P.4
Young, A.5
-
27
-
-
0027184119
-
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin- secreting β-cells
-
Göke R, et al. (1993) Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J Biol Chem 268(26):19650-19655. (Pubitemid 23270754)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.26
, pp. 19650-19655
-
-
Goke, R.1
Fehmann, H.-C.2
Linn, T.3
Schmidt, H.4
Krause, M.5
Eng, J.6
Goke, B.7
-
28
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
-
Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC (2011) Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 141(1):150-156.
-
(2011)
Gastroenterology
, vol.141
, Issue.1
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
Elashoff, R.4
Butler, P.C.5
-
29
-
-
0036790954
-
Prediction of structure and function of G protein-coupled receptors
-
Vaidehi N, et al. (2002) Prediction of structure and function of G protein-coupled receptors. Proc Natl Acad Sci USA 99(20):12622-12627.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.20
, pp. 12622-12627
-
-
Vaidehi, N.1
-
30
-
-
45549086826
-
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
-
Runge S, Thøgersen H, Madsen K, Lau J, Rudolph R (2008) Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. J Biol Chem 283 (17):11340-11347.
-
(2008)
J Biol Chem
, vol.283
, Issue.17
, pp. 11340-11347
-
-
Runge, S.1
Thøgersen, H.2
Madsen, K.3
Lau, J.4
Rudolph, R.5
-
31
-
-
84934443930
-
Structure prediction of g protein-coupled receptors and their ensemble of functionally important conformations
-
Abrol R, Griffith AR, Bray JK, Goddard WA, 3rd (2012) Structure prediction of g protein-coupled receptors and their ensemble of functionally important conformations. Methods Mol Biol 914:237-254.
-
(2012)
Methods Mol Biol
, vol.914
, pp. 237-254
-
-
Abrol, R.1
Griffith, A.R.2
Bray, J.K.3
Goddard III, W.A.4
-
32
-
-
34848928184
-
Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist
-
DOI 10.1021/ja070865d
-
Li Y, et al. (2007) Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist. J Am Chem Soc 129(35):10720-10731. (Pubitemid 350067482)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.35
, pp. 10720-10731
-
-
Li, Y.1
Zhu, F.2
Vaidehi, N.3
Goddard III, W.A.4
Sheinerman, F.5
Reiling, S.6
Morize, I.7
Mu, L.8
Harris, K.9
Ardati, A.10
Laoui, A.11
-
33
-
-
58149267930
-
Flat-bottom strategy for improved accuracy in protein side-chain placements
-
Kam VWT, Goddard WA (2008) Flat-bottom strategy for improved accuracy in protein side-chain placements. J Chem Theory Comput 4(12):2160-2169.
-
(2008)
J Chem Theory Comput
, vol.4
, Issue.12
, pp. 2160-2169
-
-
Kam, V.W.T.1
Goddard, W.A.2
-
34
-
-
34247561729
-
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand
-
DOI 10.1073/pnas.0700682104
-
Grace CR, et al. (2007) Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand. Proc Natl Acad Sci USA 104(12):4858-4863. (Pubitemid 47186141)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.12
, pp. 4858-4863
-
-
Grace, C.R.R.1
Perrin, M.H.2
Gulyas, J.3
DiGruccio, M.R.4
Cantle, J.P.5
Rivier, J.E.6
Vale, W.W.7
Riek, R.8
-
36
-
-
0035818410
-
Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states
-
DOI 10.1021/bi010902s
-
Neidigh JW, Fesinmeyer RM, Prickett KS, Andersen NH (2001) Exendin-4 and glucagon- like-peptide-1: NMR structural comparisons in the solution and micelle-associated states. Biochemistry 40(44):13188-13200. (Pubitemid 33043533)
-
(2001)
Biochemistry
, vol.40
, Issue.44
, pp. 13188-13200
-
-
Neidigh, J.W.1
Fesinmeyer, R.M.2
Prickett, K.S.3
Andersen, N.H.4
-
37
-
-
38049034590
-
Comparative protein structure modeling using Modeller
-
(Wiley, New York), Unit 5.6
-
Eswar N, et al. (2006) Comparative protein structure modeling using Modeller. Current Protocols in Bioinformatics (Wiley, New York), Unit 5.6.
-
(2006)
Current Protocols in Bioinformatics
-
-
Eswar, N.1
-
38
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
DOI 10.1002/jcc.20289
-
Phillips JC, et al. (2005) Scalable molecular dynamics with NAMD. J Comput Chem 26 (16):1781-1802. (Pubitemid 43078511)
-
(2005)
Journal of Computational Chemistry
, vol.26
, Issue.16
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
Villa, E.6
Chipot, C.7
Skeel, R.D.8
Kale, L.9
Schulten, K.10
-
39
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
MacKerell AD, et al. (1998) All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B 102(18):3586-3616.
-
(1998)
J Phys Chem B
, vol.102
, Issue.18
, pp. 3586-3616
-
-
MacKerell, A.D.1
-
40
-
-
67650500988
-
CHARMM: The biomolecular simulation program
-
Brooks BR, et al. (2009) CHARMM: The biomolecular simulation program. J Comput Chem 30(10):1545-1614.
-
(2009)
J Comput Chem
, vol.30
, Issue.10
, pp. 1545-1614
-
-
Brooks, B.R.1
-
41
-
-
0004016501
-
Comparison of simple potential functions for simulating liquid water
-
Jorgensen WL, Chandrasekhar J, Madura JD, Impey RW, Klein ML (1983) Comparison of simple potential functions for simulating liquid water. J Chem Phys 79(2):926-935.
-
(1983)
J Chem Phys
, vol.79
, Issue.2
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
42
-
-
44849110545
-
Notes on "Characteristics of gadolinium-DTPA complex: A potential NMR contrast agent"
-
Runge VM (2008) Notes on "Characteristics of gadolinium-DTPA complex: A potential NMR contrast agent" AJR Am J Roentgenol 190(6):1433-1434.
-
(2008)
AJR Am J Roentgenol
, vol.190
, Issue.6
, pp. 1433-1434
-
-
Runge, V.M.1
-
43
-
-
77957055780
-
Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors
-
Ballesteros A, Weinstein H (1995) Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors. Methods Neurosci 25:366-428.
-
(1995)
Methods Neurosci
, vol.25
, pp. 366-428
-
-
Ballesteros, A.1
Weinstein, H.2
-
44
-
-
45649083187
-
Functional role of the "ionic lock" - An interhelical hydrogenbond network in family A heptahelical receptors
-
Vogel R, et al. (2008) Functional role of the "ionic lock" - an interhelical hydrogenbond network in family A heptahelical receptors. J Mol Biol 380(4):648-655.
-
(2008)
J Mol Biol
, vol.380
, Issue.4
, pp. 648-655
-
-
Vogel, R.1
-
45
-
-
73949123418
-
Pharmacological characterization of human incretin receptor missense variants
-
Fortin JP, Schroeder JC, Zhu Y, Beinborn M, Kopin AS (2010) Pharmacological characterization of human incretin receptor missense variants. J Pharmacol Exp Ther 332 (1):274-280.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, Issue.1
, pp. 274-280
-
-
Fortin, J.P.1
Schroeder, J.C.2
Zhu, Y.3
Beinborn, M.4
Kopin, A.S.5
-
46
-
-
0030601059
-
Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signaling
-
DOI 10.1006/bbrc.1996.0945
-
Heller RS, Kieffer TJ, Habener JF (1996) Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signaling. Biochem Biophys Res Commun 223(3):624-632. (Pubitemid 26246123)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.223
, Issue.3
, pp. 624-632
-
-
Heller, R.S.1
Kieffer, T.J.2
Habener, J.F.3
-
47
-
-
0029913367
-
The third cytoplasmic domain of the GLP-1[7-36 amide] receptor is required for coupling to the adenylyl cyclase system
-
DOI 10.1210/en.137.5.2175
-
Takhar S, et al. (1996) The third cytoplasmic domain of the GLP-1[7-36 amide] receptor is required for coupling to the adenylyl cyclase system. Endocrinology 137(5): 2175-2178. (Pubitemid 26133992)
-
(1996)
Endocrinology
, vol.137
, Issue.5
, pp. 2175-2178
-
-
Takhar, S.1
Gyomorey, S.2
Su, R.-C.3
Mathi, S.K.4
Li, X.5
Wheeler, M.B.6
-
48
-
-
80051658642
-
Crystal structure of the β2 adrenergic receptor-Gs protein complex
-
Rasmussen SG, et al. (2011) Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature 477(7366):549-555.
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 549-555
-
-
Rasmussen, S.G.1
-
49
-
-
84855799592
-
Diversity and modularity of G protein-coupled receptor structures
-
Katritch V, Cherezov V, Stevens RC (2012) Diversity and modularity of G protein-coupled receptor structures. Trends Pharmacol Sci 33(1):17-27.
-
(2012)
Trends Pharmacol Sci
, vol.33
, Issue.1
, pp. 17-27
-
-
Katritch, V.1
Cherezov, V.2
Stevens, R.C.3
-
50
-
-
84855822647
-
The family B1 GPCR: Structural aspects and interaction with accessory proteins
-
Couvineau A, Laburthe M (2012) The family B1 GPCR: Structural aspects and interaction with accessory proteins. Curr Drug Targets 13(1):103-115.
-
(2012)
Curr Drug Targets
, vol.13
, Issue.1
, pp. 103-115
-
-
Couvineau, A.1
Laburthe, M.2
-
51
-
-
22044446844
-
A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness
-
DOI 10.1016/j.regpep.2005.05.001, PII S0167011505001229
-
Beinborn M, Worrall CI, McBride EW, Kopin AS (2005) A human glucagon-like peptide- 1 receptor polymorphism results in reduced agonist responsiveness. Regul Pept 130(1-2):1-6. (Pubitemid 40966015)
-
(2005)
Regulatory Peptides
, vol.130
, Issue.1-2
, pp. 1-6
-
-
Beinborn, M.1
Worrall, C.I.2
McBride, E.W.3
Kopin, A.S.4
-
52
-
-
80053381451
-
Residues within the transmembrane domain of the glucagon- like peptide-1 receptor involved in ligand binding and receptor activation: Modelling the ligand-bound receptor
-
Coopman K, et al. (2011) Residues within the transmembrane domain of the glucagon- like peptide-1 receptor involved in ligand binding and receptor activation: Modelling the ligand-bound receptor. Mol Endocrinol 25(10):1804-1818.
-
(2011)
Mol Endocrinol
, vol.25
, Issue.10
, pp. 1804-1818
-
-
Coopman, K.1
-
53
-
-
73649107900
-
Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor
-
Underwood CR, et al. (2010) Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor. J Biol Chem 285(1):723-730.
-
(2010)
J Biol Chem
, vol.285
, Issue.1
, pp. 723-730
-
-
Underwood, C.R.1
-
54
-
-
1542578694
-
Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues
-
DOI 10.2174/0929866043478491
-
López de Maturana R, Treece-Birch J, Abidi F, Findlay JB, Donnelly D (2004) Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues. Protein Pept Lett 11(1):15-22. (Pubitemid 38345499)
-
(2004)
Protein and Peptide Letters
, vol.11
, Issue.1
, pp. 15-22
-
-
De Maturana, R.L.1
Treece-Birch, J.2
Abidi, F.3
Findlay, J.B.C.4
Donnelly, D.5
-
55
-
-
0141992171
-
A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors
-
DOI 10.1038/sj.bjp.0705453
-
Al-Sabah S, Donnelly D (2003) A model for receptor-peptide binding at the glucagonlike peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors. Br J Pharmacol 140(2):339-346. (Pubitemid 37249194)
-
(2003)
British Journal of Pharmacology
, vol.140
, Issue.2
, pp. 339-346
-
-
Al-Sabah, S.1
Donnelly, D.2
-
56
-
-
0037163906
-
The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge
-
DOI 10.1016/S0014-5793(02)03492-0, PII S0014579302034920
-
López de Maturana R, Donnelly D (2002) The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge. FEBS Lett 530(1-3):244-248. (Pubitemid 35248219)
-
(2002)
FEBS Letters
, vol.530
, Issue.1-3
, pp. 244-248
-
-
Lopez, D.M.R.1
Donnelly, D.2
-
57
-
-
84856731249
-
Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation
-
Koole C, et al. (2012) Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation. J Biol Chem 287(6):3642-3658.
-
(2012)
J Biol Chem
, vol.287
, Issue.6
, pp. 3642-3658
-
-
Koole, C.1
-
58
-
-
16244383540
-
Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors
-
Hoare SR (2005) Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors. Drug Discov Today 10(6):417-427.
-
(2005)
Drug Discov Today
, vol.10
, Issue.6
, pp. 417-427
-
-
Hoare, S.R.1
-
59
-
-
33846477446
-
Small-molecule agonists for the glucagon-like peptide 1 receptor
-
DOI 10.1073/pnas.0605701104
-
Knudsen LB, et al. (2007) Small-molecule agonists for the glucagon-like peptide 1 receptor. Proc Natl Acad Sci USA 104(3):937-942. (Pubitemid 46154715)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 937-942
-
-
Knudsen, L.B.1
Kiel, D.2
Teng, M.3
Behrens, C.4
Bhumralkar, D.5
Kodra, J.T.6
Holst, J.J.7
Jeppesen, C.B.8
Johnson, M.D.9
De Jong, J.C.10
Jorgensen, A.S.11
Kercher, T.12
Kostrowicki, J.13
Madsen, P.14
Olesen, P.H.15
Petersen, J.S.16
Poulsen, F.17
Sidelmann, U.G.18
Sturis, J.19
Truesdale, L.20
May, J.21
Lau, J.22
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