-
1
-
-
84870587671
-
-
Current Topics in Microbiol. and Immunol: Berlin, Heidelberg,; Vol. 262 and 263. Springer-Verlag
-
Oldstone, M.B.A. Arenaviruses I and III. Current Topics in Microbiol. and Immunol: Berlin, Heidelberg, 2002; Vol. 262 and 263. Springer-Verlag.
-
(2002)
Arenaviruses I and III
-
-
Oldstone, M.B.A.1
-
2
-
-
34447299235
-
-
D.M. Knipe, P.M. Howley, et al. Eds. Lappincott Williams & Wilkins: Phyladelphia
-
Buchmeier, M.J.; de la Torre, J.C.; Peters, C.J. Arenaviridae: the viruses and their replication. D.M. Knipe, P.M. Howley, et al. Eds. Lappincott Williams & Wilkins: Phyladelphia, 2007; pp. 1791-1827.
-
(2007)
Arenaviridae: The viruses and their replication
, pp. 1791-1827
-
-
Buchmeier, M.J.1
de la Torre, J.C.2
Peters, C.J.3
-
3
-
-
67249156188
-
Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa
-
Briese, T.; Paweska, J.T.; McMullan, L.K.; Hutchison, S.K.; Street, C.; Palacios, G.; Khristova, M.L.; Weyer, J.; Swanepoel, R.; Egholm, M.; Nichol, S.T.; Lipkin, W.I. Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa. PLoS Pathog. 2009, 5, e1000455.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Briese, T.1
Paweska, J.T.2
McMullan, L.K.3
Hutchison, S.K.4
Street, C.5
Palacios, G.6
Khristova, M.L.7
Weyer, J.8
Swanepoel, R.9
Egholm, M.10
Nichol, S.T.11
Lipkin, W.I.12
-
4
-
-
84871805668
-
Rodent-borne hemorrhagic fevers: Under-recognized, widely spread and preventable-epidemiology, diagnostics and treatment
-
in press
-
Goeijenbier, M.; Wagenaar, J.; Goris, M.; Martina, B.; Henttonen, H.; Vaheri, A.; Reusken, C.; Hartskeerl, R.; Osterhaus, A.; Van Gorp, E. Rodent-borne hemorrhagic fevers: under-recognized, widely spread and preventable-epidemiology, diagnostics and treatment. Critical reviews in microbiology 2012, in press.
-
(2012)
Critical reviews in microbiology
-
-
Goeijenbier, M.1
Wagenaar, J.2
Goris, M.3
Martina, B.4
Henttonen, H.5
Vaheri, A.6
Reusken, C.7
Hartskeerl, R.8
Osterhaus, A.9
Van Gorp, E.10
-
5
-
-
0030052809
-
Lymphocytic choriomeningitis virus: A neglected central nervous system pathogen
-
Barton, L.L. Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen. Clin. Infect. Dis. 1996, 22, 197.
-
(1996)
Clin. Infect. Dis.
, vol.22
, pp. 197
-
-
Barton, L.L.1
-
6
-
-
33646875293
-
Transmission of lymphocytic choriomeningitis virus by organ transplantation
-
Fischer, S.A.; Graham, M.B.; Kuehnert, M.J.; Kotton, C.N.; Srinivasan, A.; Marty, F.M.; Comer, J.A.; Guarner, J.; Paddock, C.D.; DeMeo, D.L.; Shieh, W.J.; Erickson, B.R.; Bandy, U.; DeMaria, A., Jr.; Davis, J.P.; Delmonico, F.L.; Pavlin, B.; Likos, A.; Vincent, M.J.; Sealy, T.K.; Goldsmith, C.S.; Jernigan, D.B.; Rollin, P.E.; Packard, M.M.; Patel, M.; Rowland, C.; Helfand, R.F.; Nichol, S.T.; Fishman, J.A.; Ksiazek, T.; Zaki, S.R. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N. Engl. J. Med. 2006, 354, 2235-2249.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2235-2249
-
-
Fischer, S.A.1
Graham, M.B.2
Kuehnert, M.J.3
Kotton, C.N.4
Srinivasan, A.5
Marty, F.M.6
Comer, J.A.7
Guarner, J.8
Paddock, C.D.9
DeMeo, D.L.10
Shieh, W.J.11
Erickson, B.R.12
Bandy, U.13
DeMaria Jr., A.14
Davis, J.P.15
Delmonico, F.L.16
Pavlin, B.17
Likos, A.18
Vincent, M.J.19
Sealy, T.K.20
Goldsmith, C.S.21
Jernigan, D.B.22
Rollin, P.E.23
Packard, M.M.24
Patel, M.25
Rowland, C.26
Helfand, R.F.27
Nichol, S.T.28
Fishman, J.A.29
Ksiazek, T.30
Zaki, S.R.31
more..
-
7
-
-
33646770959
-
Lymphocytic choriomeningitis virus: An emerging obstetric pathogen?
-
Jamieson, D.J.; Kourtis, A.P.; Bell, M.; Rasmussen, S.A. Lymphocytic choriomeningitis virus: an emerging obstetric pathogen? Am. J. Obstet. Gynecol. 2006, 194(6), 1532-1536.
-
(2006)
Am. J. Obstet. Gynecol.
, vol.194
, Issue.6
, pp. 1532-1536
-
-
Jamieson, D.J.1
Kourtis, A.P.2
Bell, M.3
Rasmussen, S.A.4
-
8
-
-
40449115382
-
A new arenavirus in a cluster of fatal transplant-associated diseases
-
Palacios, G.; Druce, J.; Du, L.; Tran, T.; Birch, C.; Briese, T.; Conlan, S.; Quan, P.L.; Hui, J.; Marshall, J.; Simons, J.F.; Egholm, M.; Paddock, C.D.; Shieh, W.J.; Goldsmith, C.S.; Zaki, S.R.; Catton, M.; Lipkin, W.I. A new arenavirus in a cluster of fatal transplant-associated diseases. N. Engl. J. Med. 2008, 358, 991-998.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 991-998
-
-
Palacios, G.1
Druce, J.2
Du, L.3
Tran, T.4
Birch, C.5
Briese, T.6
Conlan, S.7
Quan, P.L.8
Hui, J.9
Marshall, J.10
Simons, J.F.11
Egholm, M.12
Paddock, C.D.13
Shieh, W.J.14
Goldsmith, C.S.15
Zaki, S.R.16
Catton, M.17
Lipkin, W.I.18
-
9
-
-
79959370883
-
Argentine hemorrhagic fever vaccines
-
Ambrosio, A.; Saavedra, M.; Mariani, M.; Gamboa, G.; Maiza, A. Argentine hemorrhagic fever vaccines. Human vaccines 2011, 7, 694-700.
-
(2011)
Human vaccines
, vol.7
, pp. 694-700
-
-
Ambrosio, A.1
Saavedra, M.2
Mariani, M.3
Gamboa, G.4
Maiza, A.5
-
10
-
-
84856567636
-
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model
-
Goicochea, M.A.; Zapata, J.C.; Bryant, J.; Davis, H.; Salvato, M.S.; Lukashevich, I.S. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model. Vaccine 2012, 30, 1445-1452.
-
(2012)
Vaccine
, vol.30
, pp. 1445-1452
-
-
Goicochea, M.A.1
Zapata, J.C.2
Bryant, J.3
Davis, H.4
Salvato, M.S.5
Lukashevich, I.S.6
-
11
-
-
84355161584
-
Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative
-
Sepulveda, C.S.; Garcia, C.C.; Fascio, M.L.; D'Accorso, N.B.; Docampo Palacios, M.L.; Pellon, R.F.; Damonte, E.B. Inhibition of Junin virus RNA synthesis by an antiviral acridone derivative. Antiviral. Res. 2012, 93, 16-22.
-
(2012)
Antiviral. Res.
, vol.93
, pp. 16-22
-
-
Sepulveda, C.S.1
Garcia, C.C.2
Fascio, M.L.3
D'Accorso, N.B.4
Docampo Palacios, M.L.5
Pellon, R.F.6
Damonte, E.B.7
-
12
-
-
80055080528
-
Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever
-
Mendenhall, M.; Russell, A.; Smee, D.F.; Hall, J.O.; Skirpstunas, R.; Furuta, Y.; Gowen, B.B. Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. PLoS neglected tropical diseases 2011, 5, e1342.
-
(2011)
PLoS neglected tropical diseases
, vol.5
-
-
Mendenhall, M.1
Russell, A.2
Smee, D.F.3
Hall, J.O.4
Skirpstunas, R.5
Furuta, Y.6
Gowen, B.B.7
-
13
-
-
56649102052
-
Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin
-
Gowen, B.B.; Smee, D.F.; Wong, M.H.; Hall, J.O.; Jung, K.H.; Bailey, K.W.; Stevens, J.R.; Furuta, Y.; Morrey, J.D. Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. PLoS One 2008, 3, e3725.
-
(2008)
PLoS One
, vol.3
-
-
Gowen, B.B.1
Smee, D.F.2
Wong, M.H.3
Hall, J.O.4
Jung, K.H.5
Bailey, K.W.6
Stevens, J.R.7
Furuta, Y.8
Morrey, J.D.9
-
14
-
-
0022630892
-
Lassa fever. Effective therapy with ribavirin
-
McCormick, J.B.; King, I.J.; Webb, P.A.; Scribner, C.L.; Craven, R.B.; Johnson, K.M.; Elliott, L.H.; Belmont-Williams, R. Lassa fever. Effective therapy with ribavirin. N. Engl. J. Med. 1986, 314, 20-26.
-
(1986)
N. Engl. J. Med.
, vol.314
, pp. 20-26
-
-
McCormick, J.B.1
King, I.J.2
Webb, P.A.3
Scribner, C.L.4
Craven, R.B.5
Johnson, K.M.6
Elliott, L.H.7
Belmont-Williams, R.8
-
15
-
-
84862579286
-
Viral quasispecies evolution
-
Domingo, E.; Sheldon, J.; Perales, C. Viral quasispecies evolution. Microbiology and Molecular Biology Reviews 2012, 76, 159-216.
-
(2012)
Microbiology and Molecular Biology Reviews
, vol.76
, pp. 159-216
-
-
Domingo, E.1
Sheldon, J.2
Perales, C.3
-
16
-
-
84055200527
-
Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID
-
Jabara, C.B.; Jones, C.D.; Roach, J.; Anderson, J.A.; Swanstrom, R. Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID. Proc. Natl. Acad. Sci. USA 2011, 108, 20166-20171.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 20166-20171
-
-
Jabara, C.B.1
Jones, C.D.2
Roach, J.3
Anderson, J.A.4
Swanstrom, R.5
-
17
-
-
33847210305
-
Fitness landscape of human immunodeficiency virus type 1 protease quasispecies
-
Fernandez, G.; Clotet, B.; Martinez, M.A. Fitness landscape of human immunodeficiency virus type 1 protease quasispecies. J. Virol. 2007, 81, 2485-2496.
-
(2007)
J. Virol.
, vol.81
, pp. 2485-2496
-
-
Fernandez, G.1
Clotet, B.2
Martinez, M.A.3
-
18
-
-
0034646357
-
Viral persistence in vivo through selection of neutralizing antibody-escape variants
-
Ciurea, A.; Klenerman, P.; Hunziker, L.; Horvath, E.; Senn, B.M.; Ochsenbein, A.F.; Hengartner, H.; Zinkernagel, R.M. Viral persistence in vivo through selection of neutralizing antibody-escape variants. Proc. Natl. Acad. Sci. USA 2000, 97, 2749-2754.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2749-2754
-
-
Ciurea, A.1
Klenerman, P.2
Hunziker, L.3
Horvath, E.4
Senn, B.M.5
Ochsenbein, A.F.6
Hengartner, H.7
Zinkernagel, R.M.8
-
19
-
-
0026323705
-
In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes
-
Aebischer, T.; Moskophidis, D.; Rohrer, U.H.; Zinkernagel, R.M.; Hengartner, H. In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA 1991, 88, 11047-11051.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 11047-11051
-
-
Aebischer, T.1
Moskophidis, D.2
Rohrer, U.H.3
Zinkernagel, R.M.4
Hengartner, H.5
-
20
-
-
0025913807
-
Molecular basis of organ-specific selection of viral variants during chronic infection
-
Ahmed, R.; Hahn, C.S.; Somasundaram, T.; Villarete, L.; Matloubian, M.; Strauss, J.H. Molecular basis of organ-specific selection of viral variants during chronic infection. J. Virol. 1991, 65, 4242-4247.
-
(1991)
J. Virol.
, vol.65
, pp. 4242-4247
-
-
Ahmed, R.1
Hahn, C.S.2
Somasundaram, T.3
Villarete, L.4
Matloubian, M.5
Strauss, J.H.6
-
21
-
-
0023734872
-
Genetic analysis of in vivo-selected viral variants causing chronic infection: Importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus
-
Ahmed, R.; Simon, R.S.; Matloubian, M.; Kolhekar, S.R.; Southern, P.J.; Freedman, D.M. Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus. J. Virol. 1988, 62, 3301-3308.
-
(1988)
J. Virol.
, vol.62
, pp. 3301-3308
-
-
Ahmed, R.1
Simon, R.S.2
Matloubian, M.3
Kolhekar, S.R.4
Southern, P.J.5
Freedman, D.M.6
-
22
-
-
0029926534
-
Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus
-
Buesa-Gomez, J.; Teng, M.N.; Oldstone, C.E.; Oldstone, M.B.; de la Torre, J.C. Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus. J. Virol. 1996, 70, 8988-8992.
-
(1996)
J. Virol.
, vol.70
, pp. 8988-8992
-
-
Buesa-Gomez, J.1
Teng, M.N.2
Oldstone, C.E.3
Oldstone, M.B.4
de la Torre, J.C.5
-
23
-
-
0034928717
-
CD4+ T-cell-epitope escape mutant virus selected in vivo
-
Ciurea, A.; Hunziker, L.; Martinic, M.M.; Oxenius, A.; Hengartner, H.; Zinkernagel, R.M. CD4+ T-cell-epitope escape mutant virus selected in vivo. Nat. Med. 2001, 7, 795-800.
-
(2001)
Nat. Med.
, vol.7
, pp. 795-800
-
-
Ciurea, A.1
Hunziker, L.2
Martinic, M.M.3
Oxenius, A.4
Hengartner, H.5
Zinkernagel, R.M.6
-
24
-
-
0030067698
-
Competitive selection in vivo by a cell for one variant over another: Implications for RNA virus quasispecies in vivo
-
Dockter, J.; Evans, C.F.; Tishon, A.; Oldstone, M.B. Competitive selection in vivo by a cell for one variant over another: implications for RNA virus quasispecies in vivo. J. Virol. 1996, 70, 1799-1803.
-
(1996)
J. Virol.
, vol.70
, pp. 1799-1803
-
-
Dockter, J.1
Evans, C.F.2
Tishon, A.3
Oldstone, M.B.4
-
25
-
-
0027948131
-
Virus-induced immunosuppression: Kinetic analysis of the selection of a mutation associated with viral persistence
-
Evans, C.F.; Borrow, P.; de la Torre, J.C.; Oldstone, M.B. Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence. J. Virol. 1994, 68, 7367-7373.
-
(1994)
J. Virol.
, vol.68
, pp. 7367-7373
-
-
Evans, C.F.1
Borrow, P.2
de la Torre, J.C.3
Oldstone, M.B.4
-
26
-
-
0027361735
-
Molecular determinants of macrophage tropism and viral persistence: Importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus
-
Matloubian, M.; Kolhekar, S.R.; Somasundaram, T.; Ahmed, R. Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus. J. Virol. 1993, 67, 7340-7349.
-
(1993)
J. Virol.
, vol.67
, pp. 7340-7349
-
-
Matloubian, M.1
Kolhekar, S.R.2
Somasundaram, T.3
Ahmed, R.4
-
27
-
-
0025155817
-
Genetic basis of viral persistence: Single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice
-
Matloubian, M.; Somasundaram, T.; Kolhekar, S.R.; Selvakumar, R.; Ahmed, R. Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice. J. Exp. Med. 1990, 172, 1043-1048.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1043-1048
-
-
Matloubian, M.1
Somasundaram, T.2
Kolhekar, S.R.3
Selvakumar, R.4
Ahmed, R.5
-
28
-
-
0024992268
-
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo
-
Pircher, H.; Moskophidis, D.; Rohrer, U.; Burki, K.; Hengartner, H.; Zinkernagel, R.M. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature 1990, 346, 629-633.
-
(1990)
Nature
, vol.346
, pp. 629-633
-
-
Pircher, H.1
Moskophidis, D.2
Rohrer, U.3
Burki, K.4
Hengartner, H.5
Zinkernagel, R.M.6
-
29
-
-
0026088714
-
Molecular basis of viral persistence: A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence
-
Salvato, M.; Borrow, P.; Shimomaye, E.; Oldstone, M.B. Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence. J. Virol. 1991, 65, 1863-1869.
-
(1991)
J. Virol.
, vol.65
, pp. 1863-1869
-
-
Salvato, M.1
Borrow, P.2
Shimomaye, E.3
Oldstone, M.B.4
-
30
-
-
0029861655
-
A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome
-
Teng, M.N.; Borrow, P.; Oldstone, M.B.; de la Torre, J.C. A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome. J. Virol. 1996, 70, 8438-8443.
-
(1996)
J. Virol.
, vol.70
, pp. 8438-8443
-
-
Teng, M.N.1
Borrow, P.2
Oldstone, M.B.3
de la Torre, J.C.4
-
31
-
-
0038623874
-
Public versus personal serotypes of a viral quasispecies
-
Hunziker, L.; Ciurea, A.; Recher, M.; Hengartner, H.; Zinkernagel, R.M. Public versus personal serotypes of a viral quasispecies. Proc. Natl. Acad. Sci. USA 2003, 100, 6015-6020.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6015-6020
-
-
Hunziker, L.1
Ciurea, A.2
Recher, M.3
Hengartner, H.4
Zinkernagel, R.M.5
-
32
-
-
0030247470
-
Suppression of lymphocytic choriomeningitis virus-induced growth hormone deficiency syndrome by disease-negative virus variants
-
Teng, M.N.; Oldstone, M.B.; de la Torre, J.C. Suppression of lymphocytic choriomeningitis virus-induced growth hormone deficiency syndrome by disease-negative virus variants. Virology 1996, 223, 113-119.
-
(1996)
Virology
, vol.223
, pp. 113-119
-
-
Teng, M.N.1
Oldstone, M.B.2
de la Torre, J.C.3
-
33
-
-
0036189270
-
Contribution of LCMV towards deciphering biology of quasispecies in vivo
-
Sevilla, N.; Domingo, E.; de la Torre, J.C. Contribution of LCMV towards deciphering biology of quasispecies in vivo. Curr. Top. Microbiol. Immunol. 2002, 263, 197-220.
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.263
, pp. 197-220
-
-
Sevilla, N.1
Domingo, E.2
de la Torre, J.C.3
-
34
-
-
30644470969
-
Arenavirus Diversity And Evolution: Quasispecies In Vivo
-
In
-
Sevilla, N.; de la Torre, J.C., Arenavirus Diversity And Evolution: Quasispecies In Vivo. In Cur. Top. Microbiol. Immunol. 2006; Vol. 299, pp 315-335.
-
(2006)
Cur. Top. Microbiol. Immunol.
, vol.299
, pp. 315-335
-
-
Sevilla, N.1
de la Torre, J.C.2
-
35
-
-
0036789885
-
Molecular indetermination in the transition to error catastrophe: Systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity
-
Grande-Pérez, A.; Sierra, S.; Castro, M.G.; Domingo, E.; Lowenstein, P.R. Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity. Proc. Natl. Acad. Sci. USA 2002, 99, 12938-12943.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12938-12943
-
-
Grande-Pérez, A.1
Sierra, S.2
Castro, M.G.3
Domingo, E.4
Lowenstein, P.R.5
-
36
-
-
23244443638
-
Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence
-
Grande-Pérez, A.; Gómez-Mariano, G.; Lowenstein, P.R.; Domingo, E. Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. J. Virol. 2005, 79, 10451-10459.
-
(2005)
J. Virol.
, vol.79
, pp. 10451-10459
-
-
Grande-Pérez, A.1
Gómez-Mariano, G.2
Lowenstein, P.R.3
Domingo, E.4
-
37
-
-
0345578679
-
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)
-
Ruiz-Jarabo, C.M.; Ly, C.; Domingo, E.; de la Torre, J.C. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology 2003, 308, 37-47.
-
(2003)
Virology
, vol.308
, pp. 37-47
-
-
Ruiz-Jarabo, C.M.1
Ly, C.2
Domingo, E.3
de la Torre, J.C.4
-
38
-
-
77949527717
-
An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis
-
Martin, V.; Abia, D.; Domingo, E.; Grande-Perez, A. An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis. J. Gen. Virol. 2010, 91, 990-1003.
-
(2010)
J. Gen. Virol.
, vol.91
, pp. 990-1003
-
-
Martin, V.1
Abia, D.2
Domingo, E.3
Grande-Perez, A.4
-
39
-
-
79960387914
-
Ribavirin can be mutagenic for arenaviruses
-
Moreno, H.; Gallego, I.; Sevilla, N.; de la Torre, J.C.; Domingo, E.; Martin, V. Ribavirin can be mutagenic for arenaviruses. J. Virol. 2011, 85, 7246-7255.
-
(2011)
J. Virol.
, vol.85
, pp. 7246-7255
-
-
Moreno, H.1
Gallego, I.2
Sevilla, N.3
de la Torre, J.C.4
Domingo, E.5
Martin, V.6
-
40
-
-
84858602051
-
Mutagenesis-mediated virus extinction: Virus-dependent effect of viral load on sensitivity to lethal defection
-
Moreno, H.; Tejero, H.; de la Torre, J.C.; Domingo, E.; Martin, V. Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. PLoS One 2012, 7, e32550.
-
(2012)
PLoS One
, vol.7
-
-
Moreno, H.1
Tejero, H.2
de la Torre, J.C.3
Domingo, E.4
Martin, V.5
-
41
-
-
70350132524
-
Therapeutically targeting RNA viruses via lethal mutagenesis
-
Graci, J.D.; Cameron, C.E. Therapeutically targeting RNA viruses via lethal mutagenesis. Future Virol. 2008, 3, 553-566.
-
(2008)
Future Virol.
, vol.3
, pp. 553-566
-
-
Graci, J.D.1
Cameron, C.E.2
-
42
-
-
0003901399
-
-
A principle of natural self-organization. Springer: Berlin
-
Eigen, M.; Schuster, P. The hypercycle. A principle of natural self-organization. Springer: Berlin, 1979.
-
(1979)
The hypercycle
-
-
Eigen, M.1
Schuster, P.2
-
44
-
-
80052836937
-
Safety, Tolerability, and Pharmacokinetics of KP-1461 in Phase I Clinical Studies: A Single Oral Dose Study in Non-HIV-Infected Adults, and a 14-Day Dose-Escalating Study in Highly Antiretroviral-Experienced HIV-Infected Adults
-
Clay, P.G.; McRae, M.; Laurent, J.P. Safety, Tolerability, and Pharmacokinetics of KP-1461 in Phase I Clinical Studies: A Single Oral Dose Study in Non-HIV-Infected Adults, and a 14-Day Dose-Escalating Study in Highly Antiretroviral-Experienced HIV-Infected Adults. J. Int. Assoc. Physicians AIDS Care (Chic) 2011, 10, 232-238.
-
(2011)
J. Int. Assoc. Physicians AIDS Care (Chic)
, vol.10
, pp. 232-238
-
-
Clay, P.G.1
McRae, M.2
Laurent, J.P.3
-
45
-
-
20444414897
-
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis
-
Harris, K.S.; Brabant, W.; Styrchak, S.; Gall, A.; Daifuku, R. KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis. Antiviral Res. 2005, 67, 1-9.
-
(2005)
Antiviral Res.
, vol.67
, pp. 1-9
-
-
Harris, K.S.1
Brabant, W.2
Styrchak, S.3
Gall, A.4
Daifuku, R.5
-
46
-
-
84872951243
-
Safety, Tolerability, and Efficacy of KP-1461 as Monotherapy for 124 Days in Antiretroviral-Experienced, HIV Type 1-Infected Subjects
-
in press
-
Hicks, C.; Clay, P.; Redfield, R.; Lalezari, J.; Liporace, R.; Schneider, S.; Sension, M.; McRae, M.; Laurent, J.P. Safety, Tolerability, and Efficacy of KP-1461 as Monotherapy for 124 Days in Antiretroviral-Experienced, HIV Type 1-Infected Subjects. AIDS research and human retroviruses 2012, in press.
-
(2012)
AIDS research and human retroviruses
-
-
Hicks, C.1
Clay, P.2
Redfield, R.3
Lalezari, J.4
Liporace, R.5
Schneider, S.6
Sension, M.7
McRae, M.8
Laurent, J.P.9
-
47
-
-
34548124606
-
Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase
-
Harki, D.A.; Graci, J.D.; Edathil, J.P.; Castro, C.; Cameron, C.E.; Peterson, B.R. Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase. Biochemistry 2007, 8, 1359-1362.
-
(2007)
Biochemistry
, vol.8
, pp. 1359-1362
-
-
Harki, D.A.1
Graci, J.D.2
Edathil, J.P.3
Castro, C.4
Cameron, C.E.5
Peterson, B.R.6
-
48
-
-
33750111990
-
Synthesis and antiviral activity of 5-substituted cytidine analogues: Identification of a potent inhibitor of viral RNA-dependent RNA polymerases
-
Harki, D.A.; Graci, J.D.; Galarraga, J.E.; Chain, W.J.; Cameron, C.E.; Peterson, B.R. Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases. J. Med. Chem. 2006, 49, 6166-6169.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6166-6169
-
-
Harki, D.A.1
Graci, J.D.2
Galarraga, J.E.3
Chain, W.J.4
Cameron, C.E.5
Peterson, B.R.6
-
49
-
-
0037162434
-
Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole
-
Harki, D.A.; Graci, J.D.; Korneeva, V.S.; Ghosh, S.K.; Hong, Z.; Cameron, C.E.; Peterson, B.R. Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole. Biochemistry 2002, 41, 9026-9033.
-
(2002)
Biochemistry
, vol.41
, pp. 9026-9033
-
-
Harki, D.A.1
Graci, J.D.2
Korneeva, V.S.3
Ghosh, S.K.4
Hong, Z.5
Cameron, C.E.6
Peterson, B.R.7
-
51
-
-
79251565236
-
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461
-
Mullins, J.I.; Heath, L.; Hughes, J.P.; Kicha, J.; Styrchak, S.; Wong, K.G.; Rao, U.; Hansen, A.; Harris, K.S.; Laurent, J.P.; Li, D.; Simpson, J.H.; Essigmann, J.M.; Loeb, L.A.; Parkins, J. Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461. PLoS One 2011, 6, e15135.
-
(2011)
PLoS One
, vol.6
-
-
Mullins, J.I.1
Heath, L.2
Hughes, J.P.3
Kicha, J.4
Styrchak, S.5
Wong, K.G.6
Rao, U.7
Hansen, A.8
Harris, K.S.9
Laurent, J.P.10
Li, D.11
Simpson, J.H.12
Essigmann, J.M.13
Loeb, L.A.14
Parkins, J.15
-
52
-
-
0023244181
-
Sindbis virus mutants resistant to mycophenolic acid and ribavirin
-
Scheidel, L.M.; Durbin, R.K.; Stollar, V. Sindbis virus mutants resistant to mycophenolic acid and ribavirin. Virology 1987, 158, 1-7.
-
(1987)
Virology
, vol.158
, pp. 1-7
-
-
Scheidel, L.M.1
Durbin, R.K.2
Stollar, V.3
-
53
-
-
0025752329
-
Mutations that confer resistance to mycophenolic acid and ribavirin on Sindbis virus map to the nonstructural protein nsP1
-
Scheidel, L.M.; Stollar, V. Mutations that confer resistance to mycophenolic acid and ribavirin on Sindbis virus map to the nonstructural protein nsP1. Virology 1991, 181, 490-499.
-
(1991)
Virology
, vol.181
, pp. 490-499
-
-
Scheidel, L.M.1
Stollar, V.2
-
54
-
-
0033587193
-
SVMPA, a mutant of sindbis virus resistant to mycophenolic acid and ribavirin, shows an increased sensitivity to chick interferon
-
Rosenblum, C.I.; Stollar, V. SVMPA, a mutant of sindbis virus resistant to mycophenolic acid and ribavirin, shows an increased sensitivity to chick interferon. Virology 1999, 259, 228-233.
-
(1999)
Virology
, vol.259
, pp. 228-233
-
-
Rosenblum, C.I.1
Stollar, V.2
-
55
-
-
77958122066
-
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape
-
Agudo, R.; Ferrer-Orta, C.; Arias, A.; de la Higuera, I.; Perales, C.; Perez-Luque, R.; Verdaguer, N.; Domingo, E. A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. PLoS Pathog. 2010, 6, e1001072.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Agudo, R.1
Ferrer-Orta, C.2
Arias, A.3
de la Higuera, I.4
Perales, C.5
Perez-Luque, R.6
Verdaguer, N.7
Domingo, E.8
-
56
-
-
0038809107
-
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
-
Pfeiffer, J.K.; Kirkegaard, K. A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Proc. Natl. Acad. Sci. USA 2003, 100, 7289-7294.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7289-7294
-
-
Pfeiffer, J.K.1
Kirkegaard, K.2
-
57
-
-
33745490138
-
Increased fidelity reduces poliovirus fitness under selective pressure in mice
-
Pfeiffer, J.K.; Kirkegaard, K. Increased fidelity reduces poliovirus fitness under selective pressure in mice. PLoS Pathog. 2005, 1, 102-110.
-
(2005)
PLoS Pathog.
, vol.1
, pp. 102-110
-
-
Pfeiffer, J.K.1
Kirkegaard, K.2
-
58
-
-
31144465690
-
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population
-
Vignuzzi, M.; Stone, J.K.; Arnold, J.J.; Cameron, C.E.; Andino, R. Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature 2006, 439, 344-348.
-
(2006)
Nature
, vol.439
, pp. 344-348
-
-
Vignuzzi, M.1
Stone, J.K.2
Arnold, J.J.3
Cameron, C.E.4
Andino, R.5
-
59
-
-
57349131683
-
Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin
-
Arias, A.; Arnold, J.J.; Sierra, M.; Smidansky, E.D.; Domingo, E.; Cameron, C.E. Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin. J. Virol. 2008, 82, 12346-12355.
-
(2008)
J. Virol.
, vol.82
, pp. 12346-12355
-
-
Arias, A.1
Arnold, J.J.2
Sierra, M.3
Smidansky, E.D.4
Domingo, E.5
Cameron, C.E.6
-
60
-
-
77952710653
-
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
-
Ferrer-Orta, C.; Sierra, M.; de la Higuera, I.; Agudo, R.; Arias, A.; Perez-Luque, R.; Escarmis, C.; Domingo, E.; Verdaguer, N. Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J. Virol. 2010, 84, 6188-6199.
-
(2010)
J. Virol.
, vol.84
, pp. 6188-6199
-
-
Ferrer-Orta, C.1
Sierra, M.2
de la Higuera, I.3
Agudo, R.4
Arias, A.5
Perez-Luque, R.6
Escarmis, C.7
Domingo, E.8
Verdaguer, N.9
-
61
-
-
33846813925
-
Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: Implications for error catastrophe
-
Sierra, M.; Airaksinen, A.; González-López, C.; Agudo, R.; Arias, A.; Domingo, E. Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe. J. Virol. 2007, 81, 2012-2024.
-
(2007)
J. Virol.
, vol.81
, pp. 2012-2024
-
-
Sierra, M.1
Airaksinen, A.2
González-López, C.3
Agudo, R.4
Arias, A.5
Domingo, E.6
-
62
-
-
80051590863
-
Selection of hepatitis C virus resistant to ribavirin
-
Feigelstock, D.A.; Mihalik, K.B.; Feinstone, S.M. Selection of hepatitis C virus resistant to ribavirin. Virology journal 2011, 8, 402.
-
(2011)
Virology journal
, vol.8
, pp. 402
-
-
Feigelstock, D.A.1
Mihalik, K.B.2
Feinstone, S.M.3
-
63
-
-
80053164707
-
Arbovirus high fidelity variant loses fitness in mosquitoes and mice
-
Coffey, L.L.; Beeharry, Y.; Borderia, A.V.; Blanc, H.; Vignuzzi, M. Arbovirus high fidelity variant loses fitness in mosquitoes and mice. Proc. Natl. Acad. Sci. USA 2011, 108, 16038-16043.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16038-16043
-
-
Coffey, L.L.1
Beeharry, Y.2
Borderia, A.V.3
Blanc, H.4
Vignuzzi, M.5
-
64
-
-
13444310882
-
Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA
-
Pfeiffer, J.K.; Kirkegaard, K. Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA. J. Virol. 2005, 79, 2346-2355.
-
(2005)
J. Virol.
, vol.79
, pp. 2346-2355
-
-
Pfeiffer, J.K.1
Kirkegaard, K.2
-
65
-
-
78449244303
-
Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds
-
Levi, L.I.; Gnadig, N.F.; Beaucourt, S.; McPherson, M.J.; Baron, B.; Arnold, J.J.; Vignuzzi, M. Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds. PLoS Pathog. 2010, 6, e1001163.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Levi, L.I.1
Gnadig, N.F.2
Beaucourt, S.3
McPherson, M.J.4
Baron, B.5
Arnold, J.J.6
Vignuzzi, M.7
-
66
-
-
0141755411
-
Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy
-
Young, K.C.; Lindsay, K.L.; Lee, K.J.; Liu, W.C.; He, J.W.; Milstein, S.L.; Lai, M.M. Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy. Hepatology 2003, 38, 869-878.
-
(2003)
Hepatology
, vol.38
, pp. 869-878
-
-
Young, K.C.1
Lindsay, K.L.2
Lee, K.J.3
Liu, W.C.4
He, J.W.5
Milstein, S.L.6
Lai, M.M.7
-
67
-
-
15444379112
-
Suppression of viral infectivity through lethal defection
-
Grande-Pérez, A.; Lazaro, E.; Lowenstein, P.; Domingo, E.; Manrubia, S.C. Suppression of viral infectivity through lethal defection. Proc. Natl. Acad. Sci. USA 2005, 102, 4448-4452.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4448-4452
-
-
Grande-Pérez, A.1
Lazaro, E.2
Lowenstein, P.3
Domingo, E.4
Manrubia, S.C.5
-
68
-
-
0037108885
-
Error catastrophe and antiviral strategy
-
Eigen, M. Error catastrophe and antiviral strategy. Proc. Natl. Acad. Sci. USA 2002, 99, 13374-13376.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13374-13376
-
-
Eigen, M.1
-
69
-
-
0025284804
-
Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis
-
Holland, J.J.; Domingo, E.; de la Torre, J.C.; Steinhauer, D.A. Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis. J. Virol. 1990, 64, 3960-3962.
-
(1990)
J. Virol.
, vol.64
, pp. 3960-3962
-
-
Holland, J.J.1
Domingo, E.2
de la Torre, J.C.3
Steinhauer, D.A.4
-
70
-
-
0033573932
-
Lethal mutagenesis of HIV with mutagenic nucleoside analogs
-
Loeb, L.A.; Essigmann, J.M.; Kazazi, F.; Zhang, J.; Rose, K.D.; Mullins, J.I. Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Proc. Natl. Acad. Sci. USA 1999, 96, 1492-1497.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1492-1497
-
-
Loeb, L.A.1
Essigmann, J.M.2
Kazazi, F.3
Zhang, J.4
Rose, K.D.5
Mullins, J.I.6
-
71
-
-
0033850837
-
Response of foot-and-mouth disease virus to increased mutagenesis. Influence of viral load and fitness in loss of infectivity
-
Sierra, S.; Dávila, M.; Lowenstein, P.R.; Domingo, E. Response of foot-and-mouth disease virus to increased mutagenesis. Influence of viral load and fitness in loss of infectivity. J. Virol. 2000, 74, 8316-8323.
-
(2000)
J. Virol.
, vol.74
, pp. 8316-8323
-
-
Sierra, S.1
Dávila, M.2
Lowenstein, P.R.3
Domingo, E.4
-
72
-
-
0034532953
-
The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen
-
Crotty, S.; Maag, D.; Arnold, J.J.; Zhong, W.; Lau, J.Y.N.; Hong, Z.; Andino, R.; Cameron, C.E. The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen. Nature Medicine 2000, 6, 1375-1379.
-
(2000)
Nature Medicine
, vol.6
, pp. 1375-1379
-
-
Crotty, S.1
Maag, D.2
Arnold, J.J.3
Zhong, W.4
Lau, J.Y.N.5
Hong, Z.6
Andino, R.7
Cameron, C.E.8
-
73
-
-
73549116556
-
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections
-
Perales, C.; Agudo, R.; Tejero, H.; Manrubia, S.C.; Domingo, E. Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. PLoS Pathog. 2009, 5, e1000658.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Perales, C.1
Agudo, R.2
Tejero, H.3
Manrubia, S.C.4
Domingo, E.5
-
75
-
-
80053158199
-
Tempo and mode of inhibitor-mutagen antiviral therapies: A multidisciplinary approach
-
Iranzo, J.; Perales, C.; Domingo, E.; Manrubia, S.C. Tempo and mode of inhibitor-mutagen antiviral therapies: A multidisciplinary approach. Proc. Natl. Acad. Sci. USA 2011, 108, 16008-16013.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16008-16013
-
-
Iranzo, J.1
Perales, C.2
Domingo, E.3
Manrubia, S.C.4
-
76
-
-
70350291512
-
5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1
-
Dapp, M.J.; Clouser, C.L.; Patterson, S.; Mansky, L.M. 5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. J. Virol. 2009, 83, 11950-11958.
-
(2009)
J. Virol.
, vol.83
, pp. 11950-11958
-
-
Dapp, M.J.1
Clouser, C.L.2
Patterson, S.3
Mansky, L.M.4
-
77
-
-
76549118168
-
Stochastic extinction of viral infectivity through the action of defectors
-
Iranzo, J.; Manrubia, S.C. Stochastic extinction of viral infectivity through the action of defectors. Europhys. Lett. 2009, 85, 18001.
-
(2009)
Europhys. Lett.
, vol.85
, pp. 18001
-
-
Iranzo, J.1
Manrubia, S.C.2
-
78
-
-
0033119814
-
Prisoner's dilemma in an RNA virus
-
Turner, P.E.; Chao, L. Prisoner's dilemma in an RNA virus. Nature 1999, 398, 441-443.
-
(1999)
Nature
, vol.398
, pp. 441-443
-
-
Turner, P.E.1
Chao, L.2
-
79
-
-
0346922470
-
Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations
-
Wilke, C.O.; Reissig, D.D.; Novella, I.S. Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations. Evolution Int. J. Org. Evolution 2004, 58, 900-905.
-
(2004)
Evolution Int. J. Org. Evolution
, vol.58
, pp. 900-905
-
-
Wilke, C.O.1
Reissig, D.D.2
Novella, I.S.3
-
80
-
-
34248577724
-
Insights into RNA virus mutant spectrum and lethal mutagenesis events: Replicative interference and complementation by multiple point mutants
-
Perales, C.; Mateo, R.; Mateu, M.G.; Domingo, E. Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants. J. Mol. Biol. 2007, 369, 985-1000.
-
(2007)
J. Mol. Biol.
, vol.369
, pp. 985-1000
-
-
Perales, C.1
Mateo, R.2
Mateu, M.G.3
Domingo, E.4
-
81
-
-
0242608085
-
Interference
-
In, Granoff, A.; Webster, R.G., Eds. Academic Press: San Diego, California
-
Youngner, J.S.; Whitaker-Dowling, P. Interference. In Encyclopedia of Virology, Granoff, A.; Webster, R.G., Eds. Academic Press: San Diego, California, 1999; Vol. 2, pp 850-854.
-
(1999)
Encyclopedia of Virology
, vol.2
, pp. 850-854
-
-
Youngner, J.S.1
Whitaker-Dowling, P.2
-
82
-
-
0025570214
-
RNA virus quasispecies populations can suppress vastly superior mutant progeny
-
de la Torre, J.C.; Holland, J.J. RNA virus quasispecies populations can suppress vastly superior mutant progeny. J. Virol. 1990, 64, 6278-6281.
-
(1990)
J. Virol.
, vol.64
, pp. 6278-6281
-
-
de la Torre, J.C.1
Holland, J.J.2
-
83
-
-
0026025541
-
Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine
-
Chumakov, K.M.; Powers, L.B.; Noonan, K.E.; Roninson, I.B.; Levenbook, I.S. Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine. Proc. Natl. Acad. Sci. USA 1991, 88, 199-203.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 199-203
-
-
Chumakov, K.M.1
Powers, L.B.2
Noonan, K.E.3
Roninson, I.B.4
Levenbook, I.S.5
-
84
-
-
22844440540
-
Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses
-
Crowder, S.; Kirkegaard, K. Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses. Nature Genetics 2005, 37, 701-709.
-
(2005)
Nature Genetics
, vol.37
, pp. 701-709
-
-
Crowder, S.1
Kirkegaard, K.2
-
85
-
-
1842510032
-
Preextinction viral RNA can interfere with infectivity
-
González-López, C.; Arias, A.; Pariente, N.; Gómez-Mariano, G.; Domingo, E. Preextinction viral RNA can interfere with infectivity. J. Virol. 2004, 78, 3319-3324.
-
(2004)
J. Virol.
, vol.78
, pp. 3319-3324
-
-
González-López, C.1
Arias, A.2
Pariente, N.3
Gómez-Mariano, G.4
Domingo, E.5
-
86
-
-
78650038621
-
Mutant spectra in virus behavior
-
Perales, C.; Lorenzo-Redondo, R.; López-Galíndez, C.; Martínez, M.A.; Domingo, E. Mutant spectra in virus behavior. Future Virology 2010, 5, 679-698.
-
(2010)
Future Virology
, vol.5
, pp. 679-698
-
-
Perales, C.1
Lorenzo-Redondo, R.2
López-Galíndez, C.3
Martínez, M.A.4
Domingo, E.5
-
87
-
-
81555214151
-
Quasispecies as a matter of fact: Viruses and beyond
-
Ojosnegros, S.; Perales, C.; Mas, A.; Domingo, E. Quasispecies as a matter of fact: viruses and beyond. Virus. Res. 2011, 162, 203-215.
-
(2011)
Virus. Res.
, vol.162
, pp. 203-215
-
-
Ojosnegros, S.1
Perales, C.2
Mas, A.3
Domingo, E.4
-
88
-
-
84866701494
-
Anti-tumor Monoclonal Antibodies in Conjunction with beta-Glucans: A Novel Anti-cancer Immunotherapy
-
in press
-
Xiang, D.; Sharma, V.R.; Freter, C.E.; Yan, J. Anti-tumor Monoclonal Antibodies in Conjunction with beta-Glucans: a Novel Anti-cancer Immunotherapy. Current medicinal chemistry 2012, in press.
-
(2012)
Current medicinal chemistry
-
-
Xiang, D.1
Sharma, V.R.2
Freter, C.E.3
Yan, J.4
-
89
-
-
84864413311
-
Recent advances in novel targeted therapies for HER2-positive breast cancer
-
Murphy, C.G.; Morris, P.G. Recent advances in novel targeted therapies for HER2-positive breast cancer. Anti-cancer drugs 2012, 23, 765-776.
-
(2012)
Anti-cancer drugs
, vol.23
, pp. 765-776
-
-
Murphy, C.G.1
Morris, P.G.2
-
90
-
-
0034813056
-
Efficient virus extinction by combinations of a mutagen and antiviral inhibitors
-
Pariente, N.; Sierra, S.; Lowenstein, P.R.; Domingo, E. Efficient virus extinction by combinations of a mutagen and antiviral inhibitors. J. Virol. 2001, 75, 9723-9730.
-
(2001)
J. Virol.
, vol.75
, pp. 9723-9730
-
-
Pariente, N.1
Sierra, S.2
Lowenstein, P.R.3
Domingo, E.4
-
91
-
-
20644470543
-
Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection
-
Tapia, N.; Fernandez, G.; Parera, M.; Gomez-Mariano, G.; Clotet, B.; Quinones-Mateu, M.; Domingo, E.; Martinez, M.A. Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. Virology 2005, 338, 1-8.
-
(2005)
Virology
, vol.338
, pp. 1-8
-
-
Tapia, N.1
Fernandez, G.2
Parera, M.3
Gomez-Mariano, G.4
Clotet, B.5
Quinones-Mateu, M.6
Domingo, E.7
Martinez, M.A.8
-
92
-
-
50149100514
-
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis
-
Agudo, R.; Arias, A.; Pariente, N.; Perales, C.; Escarmis, C.; Jorge, A.; Marina, A.; Domingo, E. Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. J. Mol. Biol. 2008, 382, 652-666.
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 652-666
-
-
Agudo, R.1
Arias, A.2
Pariente, N.3
Perales, C.4
Escarmis, C.5
Jorge, A.6
Marina, A.7
Domingo, E.8
-
93
-
-
65849141020
-
Counteracting quasispecies adaptability: Extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment
-
Perales, C.; Agudo, R.; Domingo, E. Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. PLoS ONE 2009, 4, e5554.
-
(2009)
PLoS ONE
, vol.4
-
-
Perales, C.1
Agudo, R.2
Domingo, E.3
-
94
-
-
84860782445
-
Concomitant lethal mutagenesis of human immunodeficiency virus type 1
-
Dapp, M.J.; Holtz, C.M.; Mansky, L.M. Concomitant lethal mutagenesis of human immunodeficiency virus type 1. J. Mol. Biol. 2012, 419, 158-170.
-
(2012)
J. Mol. Biol.
, vol.419
, pp. 158-170
-
-
Dapp, M.J.1
Holtz, C.M.2
Mansky, L.M.3
-
96
-
-
84855341533
-
Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242
-
Pasquato, A.; Rochat, C.; Burri, D.J.; Pasqual, G.; de la Torre, J.C.; Kunz, S. Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242. Virology 2012, 423, 14-22.
-
(2012)
Virology
, vol.423
, pp. 14-22
-
-
Pasquato, A.1
Rochat, C.2
Burri, D.J.3
Pasqual, G.4
de la Torre, J.C.5
Kunz, S.6
-
97
-
-
84855338260
-
Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin
-
Kolokoltsov, A.A.; Adhikary, S.; Garver, J.; Johnson, L.; Davey, R.A.; Vela, E.M. Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin. Arch. Virol. 2012, 157, 121-127.
-
(2012)
Arch. Virol.
, vol.157
, pp. 121-127
-
-
Kolokoltsov, A.A.1
Adhikary, S.2
Garver, J.3
Johnson, L.4
Davey, R.A.5
Vela, E.M.6
-
98
-
-
79952067922
-
Novel approaches in anti-arenaviral drug development
-
Lee, A.M.; Pasquato, A.; Kunz, S. Novel approaches in anti-arenaviral drug development. Virology 2011, 411, 163-169.
-
(2011)
Virology
, vol.411
, pp. 163-169
-
-
Lee, A.M.1
Pasquato, A.2
Kunz, S.3
-
99
-
-
79951929147
-
Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses
-
Narayanan, A.; Bailey, C.; Kashanchi, F.; Kehn-Hall, K. Developments in antivirals against influenza, smallpox and hemorrhagic fever viruses. Expert. Opin. Investig. Drugs 2011, 20, 239-254.
-
(2011)
Expert. Opin. Investig. Drugs
, vol.20
, pp. 239-254
-
-
Narayanan, A.1
Bailey, C.2
Kashanchi, F.3
Kehn-Hall, K.4
-
100
-
-
80052855889
-
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors
-
Neuman, B.W.; Bederka, L.H.; Stein, D.A.; Ting, J.P.; Moulton, H.M.; Buchmeier, M.J. Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrob. Agents Chemother. 2011, 55, 4631-4638.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 4631-4638
-
-
Neuman, B.W.1
Bederka, L.H.2
Stein, D.A.3
Ting, J.P.4
Moulton, H.M.5
Buchmeier, M.J.6
-
101
-
-
78650655132
-
Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease
-
Urata, S.; Yun, N.; Pasquato, A.; Paessler, S.; Kunz, S.; de la Torre, J.C. Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease. J. Virol. 2011, 85, 795-803.
-
(2011)
J. Virol.
, vol.85
, pp. 795-803
-
-
Urata, S.1
Yun, N.2
Pasquato, A.3
Paessler, S.4
Kunz, S.5
de la Torre, J.C.6
-
102
-
-
0015133749
-
Self-organization of matter and the evolution of biological macromolecules
-
Eigen, M. Self-organization of matter and the evolution of biological macromolecules. Naturwissenschaften. 1971, 58, 465-523.
-
(1971)
Naturwissenschaften.
, vol.58
, pp. 465-523
-
-
Eigen, M.1
|