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Volumn 19, Issue 25, 2012, Pages 4298-4305

Anti-tumor monoclonal antibodies in conjunction with β-glucans: A novel anti-cancer immunotherapy

Author keywords

Glucans; ADCC; Cancer immunotherapy; Complement; CR3; Leukocytes; mAb; Macrophages; Neutrophils; Targeted therapy

Indexed keywords

BETA GLUCAN; BEVACIZUMAB; CETUXIMAB; COMPLEMENT COMPONENT C3 RECEPTOR; IRINOTECAN; LECTIN; MONOCLONAL ANTIBODY; POLYSACCHARIDE; RITUXIMAB; TRASTUZUMAB;

EID: 84866701494     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712802884303     Document Type: Review
Times cited : (25)

References (106)
  • 1
    • 0009376868 scopus 로고    scopus 로고
    • Encyclopædia Britannica Online: Edward Jenner.
    • Encyclopædia Britannica. Encyclopædia Britannica Online: Edward Jenner. http://www.britannica.com/EBchecked/topic/302579/Edward-Jenner.
    • Encyclopædia Britannica
  • 2
    • 84858416256 scopus 로고    scopus 로고
    • Antibody-based immunotherapy of cancer
    • Weiner, L. M.; Murray, J. C.; Shuptrine, C. W. Antibody-based immunotherapy of cancer. Cell, 2012, 148, 1081-1084.
    • (2012) Cell , vol.148 , pp. 1081-1084
    • Weiner, L.M.1    Murray, J.C.2    Shuptrine, C.W.3
  • 9
    • 34248173883 scopus 로고    scopus 로고
    • 3rd Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio, B. J.; Catalano, P. J.; Meropol, N. J.; O'Dwyer, P. J.; Mitchell, E. P.; Alberts, S. R.; Schwartz, M. A.; Benson, A. B., 3rd Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol, 2007, 25, 1539-1544.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson, A.B.8
  • 13
    • 33846678420 scopus 로고    scopus 로고
    • Cetuximab in the treatment of metastatic colorectal cancer
    • Moosmann, N.; Heinemann, V. Cetuximab in the treatment of metastatic colorectal cancer. Expert Opin Biol Ther, 2007, 7, 243-256.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 243-256
    • Moosmann, N.1    Heinemann, V.2
  • 17
    • 0036362181 scopus 로고    scopus 로고
    • Why the epidermal growth factor receptor? the rationale for cancer therapy
    • Baselga, J. Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist, 2002, 7 Suppl 4, 2-8.
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 4 , pp. 2-8
    • Baselga, J.1
  • 18
    • 0036984738 scopus 로고    scopus 로고
    • Tumor angiogenesis and accessibility: Role of vascular endothelial growth factor
    • Jain, R. K. Tumor angiogenesis and accessibility: role of vascular endothelial growth factor. Semin Oncol, 2002, 29, 3-9.
    • (2002) Semin Oncol , vol.29 , pp. 3-9
    • Jain, R.K.1
  • 19
    • 0034104375 scopus 로고    scopus 로고
    • Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
    • Shan, D.; Ledbetter, J. A.; Press, O. W. Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells. Cancer Immunol Immunother, 2000, 48, 673-683.
    • (2000) Cancer Immunol Immunother , vol.48 , pp. 673-683
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 20
    • 45549086969 scopus 로고    scopus 로고
    • And cellular cytotoxicity in antibody therapy of cancer
    • Wang, S. Y.; Weiner, G. Complement and cellular cytotoxicity in antibody therapy of cancer. Expert Opin Biol Ther, 2008, 8, 759-768.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 759-768
    • Wang, S.Y.1    Complement, W.G.2
  • 21
    • 84876320852 scopus 로고    scopus 로고
    • US FOOD DRUG ADMINISTRATION: Vectibix®(panitumumab)
    • US FOOD AND DRUG ADMINISTRATION: Vectibix®(panitumumab) http://www.accessdata.fda.gov/drugsatfda-docs/label/2009/125147s080lbl.p df.
  • 22
    • 84876315770 scopus 로고    scopus 로고
    • US FOOD DRUG ADMINISTRATION: ARZERRA (ofatumumab)
    • US FOOD AND DRUG ADMINISTRATION: ARZERRA (ofatumumab) http://www.accessdata.fda.gov/drugsatfda-docs/label/2009/125326lbl.pdf.
  • 24
    • 74849131675 scopus 로고    scopus 로고
    • Radioimmunotherapy of lymphoma: Bexxar and Zevalin
    • Goldsmith, S. J. Radioimmunotherapy of lymphoma: Bexxar and Zevalin. Semin Nucl Med, 2010, 40, 122-135.
    • (2010) Semin Nucl Med , vol.40 , pp. 122-135
    • Goldsmith, S.J.1
  • 25
    • 78650868824 scopus 로고    scopus 로고
    • Radioimmunotherapy of solid tumors: Searching for the right target
    • Song, H.; Sgouros, G. Radioimmunotherapy of solid tumors: searching for the right target. Curr Drug Deliv, 2011, 8, 26-44.
    • (2011) Curr Drug Deliv , vol.8 , pp. 26-44
    • Song, H.1    Sgouros, G.2
  • 29
    • 79955832182 scopus 로고    scopus 로고
    • Trastuzumab emtansine: A novel antibody-drug conjugate for HER2-positive breast cancer
    • Burris, H. A. Trastuzumab emtansine: a novel antibody-drug conjugate for HER2-positive breast cancer. Expert Opin Biol Ther, 2011, 11, 807-819.
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 807-819
    • Burris, H.A.1
  • 30
    • 79955037651 scopus 로고    scopus 로고
    • Targeted cytotoxic drugs emerging for cancer therapy
    • Junttila, T. T.; Tanner, M.; Isola, J. [Targeted cytotoxic drugs emerging for cancer therapy]. Duodecim, 2011, 127, 343-349.
    • (2011) Duodecim , vol.127 , pp. 343-349
    • Junttila, T.T.1    Tanner, M.2    Isola, J.3
  • 31
    • 79952992903 scopus 로고    scopus 로고
    • Immunoconjugates against solid tumors: Mind the gap
    • Ricart, A. D. Immunoconjugates against solid tumors: mind the gap. Clin Pharmacol Ther, 2011, 89, 513-523.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 513-523
    • Ricart, A.D.1
  • 32
    • 0346690258 scopus 로고    scopus 로고
    • Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells
    • Hong, F.; Hansen, R. D.; Yan, J.; Allendorf, D. J.; Baran, J. T.; Ostroff, G. R.; Ross, G. D. Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res, 2003, 63, 9023-9031.
    • (2003) Cancer Res , vol.63 , pp. 9023-9031
    • Hong, F.1    Hansen, R.D.2    Yan, J.3    Allendorf, D.J.4    Baran, J.T.5    Ostroff, G.R.6    Ross, G.D.7
  • 33
    • 3142702164 scopus 로고    scopus 로고
    • Mechanism by which orally administered beta-1, 3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models
    • Hong, F.; Yan, J.; Baran, J. T.; Allendorf, D. J.; Hansen, R. D.; Ostroff, G. R.; Xing, P. X.; Cheung, N. K.; Ross, G. D. Mechanism by which orally administered beta-1, 3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol, 2004, 173, 797-806.
    • (2004) J Immunol , vol.173 , pp. 797-806
    • Hong, F.1    Yan, J.2    Baran, J.T.3    Allendorf, D.J.4    Hansen, R.D.5    Ostroff, G.R.6    Xing, P.X.7    Cheung, N.K.8    Ross, G.D.9
  • 34
    • 0345281592 scopus 로고    scopus 로고
    • Beta-glucan a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18)
    • Yan, J.; Vetvicka, V.; Xia, Y.; Coxon, A.; Carroll, M. C.; Mayadas, T. N.; Ross, G. D. Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18). J Immunol, 1999, 163, 3045-3052.
    • (1999) J Immunol , vol.163 , pp. 3045-3052
    • Yan, J.1    Vetvicka, V.2    Xia, Y.3    Coxon, A.4    Carroll, M.C.5    Mayadas, T.N.6    Ross, G.D.7
  • 35
    • 0035999738 scopus 로고    scopus 로고
    • Oral (1->3), (1->4)-beta-D-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma
    • Cheung, N. K.; Modak, S. Oral (1->3), (1->4)-beta-D-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma. Clin Cancer Res, 2002, 8, 1217-1223.
    • (2002) Clin Cancer Res , vol.8 , pp. 1217-1223
    • Cheung, N.K.1    Modak, S.2
  • 36
    • 0036035607 scopus 로고    scopus 로고
    • Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies
    • Cheung, N. K.; Modak, S.; Vickers, A.; Knuckles, B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol Immunother, 2002, 51, 557-564.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 557-564
    • Cheung, N.K.1    Modak, S.2    Vickers, A.3    Knuckles, B.4
  • 37
    • 18044392239 scopus 로고    scopus 로고
    • Rituximab therapy of lymphoma is enhanced by orally administered (1->3), (1->4)-D-beta-glucan
    • Modak, S.; Koehne, G.; Vickers, A.; O'Reilly, R. J.; Cheung, N. K. Rituximab therapy of lymphoma is enhanced by orally administered (1->3), (1->4)-D-beta-glucan. Leuk Res, 2005, 29, 679-683.
    • (2005) Leuk Res , vol.29 , pp. 679-683
    • Modak, S.1    Koehne, G.2    Vickers, A.3    O'Reilly, R.J.4    Cheung, N.K.5
  • 38
    • 34547619005 scopus 로고    scopus 로고
    • Combined yeast {beta}-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55
    • Li, B.; Allendorf, D. J.; Hansen, R.; Marroquin, J.; Cramer, D. E.; Harris, C. L.; Yan, J. Combined yeast {beta}-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55. Cancer Res, 2007, 67, 7421-7430.
    • (2007) Cancer Res , vol.67 , pp. 7421-7430
    • Li, B.1    Allendorf, D.J.2    Hansen, R.3    Marroquin, J.4    Cramer, D.E.5    Harris, C.L.6    Yan, J.7
  • 39
    • 39749136176 scopus 로고    scopus 로고
    • Yeastderived beta-glucan augments the therapeutic efficacy mediated by antivascular endothelial growth factor monoclonal antibody in human carcinoma xenograft models
    • Salvador, C.; Li, B.; Hansen, R.; Cramer, D. E.; Kong, M.; Yan, J. Yeastderived beta-glucan augments the therapeutic efficacy mediated by antivascular endothelial growth factor monoclonal antibody in human carcinoma xenograft models. Clin Cancer Res, 2008, 14, 1239-1247.
    • (2008) Clin Cancer Res , vol.14 , pp. 1239-1247
    • Salvador, C.1    Li, B.2    Hansen, R.3    Cramer, D.E.4    Kong, M.5    Yan, J.6
  • 40
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler, G.; Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 1975, 256, 495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 41
    • 0028127304 scopus 로고
    • Phase i clinical trial using escalating singledose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney, D. G.; Liles, T. M.; Czerwinski, D. K.; Waldichuk, C.; Rosenberg, J.; Grillo-Lopez, A.; Levy, R. Phase I clinical trial using escalating singledose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood, 1994, 84, 2457-2466.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6    Levy, R.7
  • 44
    • 65749114275 scopus 로고    scopus 로고
    • Rituximab, fludarabine, and cyclophosphamide (R-FC) prolongs progression free survival in relapsed or refractory chronic lymphocytic leukemia (CLL) compared with FC alone: Final results from the international randomized phase III REACH trial
    • lba-1
    • Robak, T.;Moiseev, S.I.;Dmoszynska, A.; et al. Rituximab, Fludarabine, and cyclophosphamide (R-FC) prolongs progression free survival in relapsed or refractory chronic lymphocytic leukemia (CLL) compared with FC alone: final results from the International Randomized Phase III REACH Trial. Blood. ASH Annual Meeting Abstracts 2008;112(11):lba-1.
    • (2008) Blood. ASH Annual Meeting Abstracts , vol.112 , Issue.11
    • Robak, T.1    Moiseev, S.I.2    Dmoszynska, A.3
  • 45
    • 61849091076 scopus 로고    scopus 로고
    • Immunochemotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R) (FCR) versus fludarabine and cyclophosphamide (FC) improves response rates and progression-free survival (PFS) of previously untreated patients (pts) with advanced chronic lymphocytic leukemia (CLL). (Abstract)
    • Hallek, M.;Fingerle-Rowson, G.;Fink A-M.;et al. Immunochemotherapy with Fludarabine (F), Cyclophosphamide (C), and Rituximab (R) (FCR) Versus Fludarabine and Cyclophosphamide (FC) Improves Response Rates and Progression-Free Survival (PFS) of Previously Untreated Patients (pts) with Advanced Chronic Lymphocytic Leukemia (CLL). (Abstract). Blood 2008; 112:325.
    • (2008) Blood , vol.112 , pp. 325
    • Hallek, M.1    Fingerle-Rowson, G.2    Fink, A.-M.3
  • 46
    • 54349116244 scopus 로고    scopus 로고
    • Reduction of fatigue in Sjogren syndrome with rituximab: Results of a randomised, double-blind, placebo-controlled pilot study
    • Dass, S.; Bowman, S. J.; Vital, E. M.; Ikeda, K.; Pease, C. T.; Hamburger, J.; Richards, A.; Rauz, S.; Emery, P. Reduction of fatigue in Sjogren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study. Ann Rheum Dis, 2008, 67, 1541-1544.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1541-1544
    • Dass, S.1    Bowman, S.J.2    Vital, E.M.3    Ikeda, K.4    Pease, C.T.5    Hamburger, J.6    Richards, A.7    Rauz, S.8    Emery, P.9
  • 49
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D. J.; Clark, G. M.; Wong, S. G.; Levin, W. J.; Ullrich, A.; McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (New York, N.Y, 1987, 235, 177-182.
    • (1987) Science (New York, N.Y.) , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 50
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • Clynes, R. A.; Towers, T. L.; Presta, L. G.; Ravetch, J. V. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med, 2000, 6, 443-446.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 51
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab-mechanism of action and use in clinical practice
    • Hudis, C. A. Trastuzumab-mechanism of action and use in clinical practice. The New England journal of medicine, 2007, 357, 39-51.
    • (2007) The New England Journal of Medicine , vol.357 , pp. 39-51
    • Hudis, C.A.1
  • 52
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang, Y. J.; Van Cutsem, E.; Feyereislova, A.; Chung, H. C.; Shen, L.; Sawaki, A.; Lordick, F.; Ohtsu, A.; Omuro, Y.; Satoh, T.; Aprile, G.; Kulikov, E.; Hill, J.; Lehle, M.; Ruschoff, J.; Kang, Y. K. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet, 2010, 376, 687-697.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6    Lordick, F.7    Ohtsu, A.8    Omuro, Y.9    Satoh, T.10    Aprile, G.11    Kulikov, E.12    Hill, J.13    Lehle, M.14    Ruschoff, J.15    Kang, Y.K.16
  • 53
    • 1642533527 scopus 로고    scopus 로고
    • Cetuximab: In the treatment of metastatic colorectal cancer
    • discussion 119-121
    • Reynolds, N. A.; Wagstaff, A. J. Cetuximab: in the treatment of metastatic colorectal cancer. Drugs, 2004, 64, 109-118; discussion 119-121.
    • (2004) Drugs , vol.64 , pp. 109-118
    • Reynolds, N.A.1    Wagstaff, A.J.2
  • 55
    • 8744262693 scopus 로고    scopus 로고
    • Integration of novel agents in the treatment of colorectal cancer
    • Iqbal, S.; Lenz, H. J. Integration of novel agents in the treatment of colorectal cancer. Cancer Chemother Pharmacol, 2004, 54 Suppl 1, S32-39.
    • (2004) Cancer Chemother Pharmacol , vol.54 , Issue.SUPPL. 1
    • Iqbal, S.1    Lenz, H.J.2
  • 56
    • 33644697486 scopus 로고    scopus 로고
    • Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
    • Folprecht, G.; Lutz, M. P.; Schoffski, P.; Seufferlein, T.; Nolting, A.; Pollert, P.; Kohne, C. H. Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol, 2006, 17, 450-456.
    • (2006) Ann Oncol , vol.17 , pp. 450-456
    • Folprecht, G.1    Lutz, M.P.2    Schoffski, P.3    Seufferlein, T.4    Nolting, A.5    Pollert, P.6    Kohne, C.H.7
  • 58
    • 0036282502 scopus 로고    scopus 로고
    • Inhibition of angiogenesis: Treatment options for patients with metastatic prostate cancer
    • Figg, W. D.; Kruger, E. A.; Price, D. K.; Kim, S.; Dahut, W. D. Inhibition of angiogenesis: treatment options for patients with metastatic prostate cancer. Invest New Drugs, 2002, 20, 183-194.
    • (2002) Invest New Drugs , vol.20 , pp. 183-194
    • Figg, W.D.1    Kruger, E.A.2    Price, D.K.3    Kim, S.4    Dahut, W.D.5
  • 59
    • 0036677084 scopus 로고    scopus 로고
    • Targeting vascular endothelial growth factor in colorectal cancer
    • Berlin, J. D. Targeting vascular endothelial growth factor in colorectal cancer. Oncology (Williston Park), 2002, 16, 13-15.
    • (2002) Oncology (Williston Park) , vol.16 , pp. 13-15
    • Berlin, J.D.1
  • 60
    • 0033018871 scopus 로고    scopus 로고
    • Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans
    • Mordenti, J.; Thomsen, K.; Licko, V.; Chen, H.; Meng, Y. G.; Ferrara, N. Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans. Toxicol Pathol, 1999, 27, 14-21.
    • (1999) Toxicol Pathol , vol.27 , pp. 14-21
    • Mordenti, J.1    Thomsen, K.2    Licko, V.3    Chen, H.4    Meng, Y.G.5    Ferrara, N.6
  • 61
    • 0035431418 scopus 로고    scopus 로고
    • Clinical trials referral resource: Current clinical trials of the anti-VEGF monoclonal antibody bevacizumab
    • 1020 1023-1016
    • Chen, H. X.; Gore-Langton, R. E.; Cheson, B. D. Clinical trials referral resource: Current clinical trials of the anti-VEGF monoclonal antibody bevacizumab. Oncology (Williston Park), 2001, 15, 1017, 1020, 1023-1016.
    • (2001) Oncology (Williston Park) , vol.15 , pp. 1017
    • Chen, H.X.1    Gore-Langton, R.E.2    Cheson, B.D.3
  • 62
    • 0035253739 scopus 로고    scopus 로고
    • Phase i safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon, M. S.; Margolin, K.; Talpaz, M.; Sledge, G. W., Jr.; Holmgren, E.; Benjamin, R.; Stalter, S.; Shak, S.; Adelman, D. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol, 2001, 19, 843-850.
    • (2001) J Clin Oncol , vol.19 , pp. 843-850
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3    Sledge Jr., G.W.4    Holmgren, E.5    Benjamin, R.6    Stalter, S.7    Shak, S.8    Adelman, D.9
  • 64
    • 0345426282 scopus 로고    scopus 로고
    • Kinetics and thermodynamics of dimer formation and dissociation for a recombinant humanized monoclonal antibody to vascular endothelial growth factor
    • Moore, J. M.; Patapoff, T. W.; Cromwell, M. E. Kinetics and thermodynamics of dimer formation and dissociation for a recombinant humanized monoclonal antibody to vascular endothelial growth factor. Biochemistry, 1999, 38, 13960-13967.
    • (1999) Biochemistry , vol.38 , pp. 13960-13967
    • Moore, J.M.1    Patapoff, T.W.2    Cromwell, M.E.3
  • 67
    • 77952318310 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
    • Rini, B. I.; Halabi, S.; Rosenberg, J. E.; Stadler, W. M.; Vaena, D. A.; Archer, L.; Atkins, J. N.; Picus, J.; Czaykowski, P.; Dutcher, J.; Small, E. J. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol, 2010, 28, 2137-2143.
    • (2010) J Clin Oncol , vol.28 , pp. 2137-2143
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3    Stadler, W.M.4    Vaena, D.A.5    Archer, L.6    Atkins, J.N.7    Picus, J.8    Czaykowski, P.9    Dutcher, J.10    Small, E.J.11
  • 68
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
    • Escudier, B.; Bellmunt, J.; Negrier, S.; Bajetta, E.; Melichar, B.; Bracarda, S.; Ravaud, A.; Golding, S.; Jethwa, S.; Sneller, V. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol, 2010, 28, 2144-2150.
    • (2010) J Clin Oncol , vol.28 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Negrier, S.3    Bajetta, E.4    Melichar, B.5    Bracarda, S.6    Ravaud, A.7    Golding, S.8    Jethwa, S.9    Sneller, V.10
  • 69
    • 0032695897 scopus 로고    scopus 로고
    • Microfibrillar structure of PGG-glucan in aqueous solution as triple-helix aggregates by small angle x-ray scattering
    • Gawronski, M.; Park, J. T.; Magee, A. S.; Conrad, H. Microfibrillar structure of PGG-glucan in aqueous solution as triple-helix aggregates by small angle x-ray scattering. Biopolymers, 1999, 50, 569-578.
    • (1999) Biopolymers , vol.50 , pp. 569-578
    • Gawronski, M.1    Park, J.T.2    Magee, A.S.3    Conrad, H.4
  • 70
    • 0032917302 scopus 로고    scopus 로고
    • Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: A modern perspective
    • Wasser, S. P.; Weis, A. L. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol, 1999, 19, 65-96.
    • (1999) Crit Rev Immunol , vol.19 , pp. 65-96
    • Wasser, S.P.1    Weis, A.L.2
  • 71
    • 20344401814 scopus 로고    scopus 로고
    • Yeast whole glucan particle (WGP) beta-glucan in conjunction with antitumour monoclonal antibodies to treat cancer
    • Yan, J.; Allendorf, D. J.; Brandley, B. Yeast whole glucan particle (WGP) beta-glucan in conjunction with antitumour monoclonal antibodies to treat cancer. Expert Opin Biol Ther, 2005, 5, 691-702.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 691-702
    • Yan, J.1    Allendorf, D.J.2    Brandley, B.3
  • 72
    • 34447300733 scopus 로고    scopus 로고
    • Yeast glucan particles activate murine resident macrophages to secrete proinflammatory cytokines via MyD88-and Syk kinase-dependent pathways
    • Li, B.; Cramer, D.; Wagner, S.; Hansen, R.; King, C.; Kakar, S.; Ding, C.; Yan, J. Yeast glucan particles activate murine resident macrophages to secrete proinflammatory cytokines via MyD88-and Syk kinase-dependent pathways. Clin Immunol, 2007, 124, 170-181.
    • (2007) Clin Immunol , vol.124 , pp. 170-181
    • Li, B.1    Cramer, D.2    Wagner, S.3    Hansen, R.4    King, C.5    Kakar, S.6    Ding, C.7    Yan, J.8
  • 74
    • 79959526149 scopus 로고    scopus 로고
    • Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived {beta}-glucans
    • Qi, C.; Cai, Y.; Gunn, L.; Ding, C.; Li, B.; Kloecker, G.; Qian, K.; Vasilakos, J.; Saijo, S.; Iwakura, Y.; Yannelli, J. R.; Yan, J. Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived {beta}-glucans. Blood, 2011, 117, 6825-6836.
    • (2011) Blood , vol.117 , pp. 6825-6836
    • Qi, C.1    Cai, Y.2    Gunn, L.3    Ding, C.4    Li, B.5    Kloecker, G.6    Qian, K.7    Vasilakos, J.8    Saijo, S.9    Iwakura, Y.10    Yannelli, J.R.11    Yan, J.12
  • 75
    • 67349174213 scopus 로고    scopus 로고
    • Combined yeast-derived beta-glucan with anti-tumor monoclonal antibody for cancer immunotherapy
    • Liu, J.; Gunn, L.; Hansen, R.; Yan, J. Combined yeast-derived beta-glucan with anti-tumor monoclonal antibody for cancer immunotherapy. Exp Mol Pathol, 2009, 86, 208-214.
    • (2009) Exp Mol Pathol , vol.86 , pp. 208-214
    • Liu, J.1    Gunn, L.2    Hansen, R.3    Yan, J.4
  • 76
    • 33746190826 scopus 로고    scopus 로고
    • Yeast beta-glucan amplifies phagocyte killing of iC3b-opsonized tumor cells via complement receptor 3-Syk-phosphatidylinositol 3-kinase pathway
    • Li, B.; Allendorf, D. J.; Hansen, R.; Marroquin, J.; Ding, C.; Cramer, D. E.; Yan, J. Yeast beta-glucan amplifies phagocyte killing of iC3b-opsonized tumor cells via complement receptor 3-Syk-phosphatidylinositol 3-kinase pathway. J Immunol, 2006, 177, 1661-1669.
    • (2006) J Immunol , vol.177 , pp. 1661-1669
    • Li, B.1    Allendorf, D.J.2    Hansen, R.3    Marroquin, J.4    Ding, C.5    Cramer, D.E.6    Yan, J.7
  • 77
    • 0034043914 scopus 로고    scopus 로고
    • Immunomodulation and anti-cancer activity of polysaccharide-protein complexes
    • Ooi, V. E.; Liu, F. Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem, 2000, 7, 715-729.
    • (2000) Curr Med Chem , vol.7 , pp. 715-729
    • Ooi, V.E.1    Liu, F.2
  • 78
    • 0018216398 scopus 로고
    • Glucan: Inhibition of tumor growth and enhancement of survival in four syngeneic murine tumor models
    • Di Luzio, N. R.; McNamee, R.; Browder, W. I.; Williams, D. Glucan:inhibition of tumor growth and enhancement of survival in four syngeneic murine tumor models. Cancer Treat Rep, 1978, 62, 1857-1866.
    • (1978) Cancer Treat Rep , vol.62 , pp. 1857-1866
    • Di Luzio, N.R.1    McNamee, R.2    Browder, W.I.3    Williams, D.4
  • 79
    • 0018612504 scopus 로고
    • Comparative tumor-inhibitory and anti-bacterial activity of soluble and particulate glucan
    • Di Luzio, N. R.; Williams, D. L.; McNamee, R. B.; Edwards, B. F.; Kitahama, A. Comparative tumor-inhibitory and anti-bacterial activity of soluble and particulate glucan. Int J Cancer, 1979, 24, 773-779.
    • (1979) Int J Cancer , vol.24 , pp. 773-779
    • Di Luzio, N.R.1    Williams, D.L.2    McNamee, R.B.3    Edwards, B.F.4    Kitahama, A.5
  • 82
    • 0023077050 scopus 로고
    • Specificity of membrane complement receptor type three (CR3) for betaglucans
    • Ross, G. D.; Cain, J. A.; Myones, B. L.; Newman, S. L.; Lachmann, P. J. Specificity of membrane complement receptor type three (CR3) for betaglucans. Complement, 1987, 4, 61-74.
    • (1987) Complement , vol.4 , pp. 61-74
    • Ross, G.D.1    Cain, J.A.2    Myones, B.L.3    Newman, S.L.4    Lachmann, P.J.5
  • 83
    • 0027160034 scopus 로고
    • CR3 (CD11b, CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions
    • Ross, G. D.; Vetvicka, V. CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Clin Exp Immunol, 1993, 92, 181-184.
    • (1993) Clin Exp Immunol , vol.92 , pp. 181-184
    • Ross, G.D.1    Vetvicka, V.2
  • 84
    • 77949475481 scopus 로고    scopus 로고
    • Supplements for immune enhancement in hematologic malignancies
    • Sze, D. M.; Chan, G. C. Supplements for immune enhancement in hematologic malignancies. Hematology Am Soc Hematol Educ Program, 2009, 313-319.
    • (2009) Hematology Am Soc Hematol Educ Program , pp. 313-319
    • Sze, D.M.1    Chan, G.C.2
  • 85
    • 0034006918 scopus 로고    scopus 로고
    • The use of mushroom glucans and proteoglycans in cancer treatment
    • Kidd, P. M. The use of mushroom glucans and proteoglycans in cancer treatment. Altern Med Rev, 2000, 5, 4-27.
    • (2000) Altern Med Rev , vol.5 , pp. 4-27
    • Kidd, P.M.1
  • 86
    • 0028273259 scopus 로고
    • Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer
    • Nakazato, H.; Koike, A.; Saji, S.; Ogawa, N.; Sakamoto, J. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer. Lancet, 1994, 343, 1122-1126.
    • (1994) Lancet , vol.343 , pp. 1122-1126
    • Nakazato, H.1    Koike, A.2    Saji, S.3    Ogawa, N.4    Sakamoto, J.5
  • 87
    • 0024243261 scopus 로고
    • Postoperative adjuvant immunochemotherapy with mitomycin C, futraful and PSK for gastric cancer. An analysis of data on 579 patients followed for five years
    • Niimoto, M.; Hattori, T.; Tamada, R.; Sugimachi, K.; Inokuchi, K.; Ogawa, N. Postoperative adjuvant immunochemotherapy with mitomycin C, futraful and PSK for gastric cancer. An analysis of data on 579 patients followed for five years. Jpn J Surg, 1988, 18, 681-686.
    • (1988) Jpn J Surg , vol.18 , pp. 681-686
    • Niimoto, M.1    Hattori, T.2    Tamada, R.3    Sugimachi, K.4    Inokuchi, K.5    Ogawa, N.6
  • 88
    • 84876320123 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society. Diet and Nutrition: Coriolus Versicolor http:// www.cancer.org/ Treatment/ Treatments and Side Effects/ Complementary and Alternative Medicine/DietandNutrition/coriolus-versicolor.
    • Diet and Nutrition: Coriolus Versicolor
  • 89
    • 0025299672 scopus 로고
    • Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer
    • Torisu, M.; Hayashi, Y.; Ishimitsu, T.; Fujimura, T.; Iwasaki, K.; Katano, M.; Yamamoto, H.; Kimura, Y.; Takesue, M.; Kondo, M.; et al. Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer. Cancer Immunol Immunother, 1990, 31, 261-268.
    • (1990) Cancer Immunol Immunother , vol.31 , pp. 261-268
    • Torisu, M.1    Hayashi, Y.2    Ishimitsu, T.3    Fujimura, T.4    Iwasaki, K.5    Katano, M.6    Yamamoto, H.7    Kimura, Y.8    Takesue, M.9    Kondo, M.10
  • 90
    • 0026520010 scopus 로고
    • Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa)
    • Mitomi, T.; Tsuchiya, S.; Iijima, N.; Aso, K.; Suzuki, K.; Nishiyama, K.; Amano, T.; Takahashi, T.; Murayama, N.; Oka, H.; et al. Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa). Dis Colon Rectum, 1992, 35, 123-130.
    • (1992) Dis Colon Rectum , vol.35 , pp. 123-130
    • Mitomi, T.1    Tsuchiya, S.2    Iijima, N.3    Aso, K.4    Suzuki, K.5    Nishiyama, K.6    Amano, T.7    Takahashi, T.8    Murayama, N.9    Oka, H.10
  • 93
    • 0001336855 scopus 로고
    • Phase II clinical trial for PSP capsules
    • Yang Q Kwok C eds Hong Kong: Fudan University Press
    • Liu J, Zhou J. Phase II clinical trial for PSP capsules. In: Yang Q, Kwok C, eds. PSP International Symposium 1993. Hong Kong: Fudan University Press; 1993:183-208.
    • (1993) PSP International Symposium , vol.1993 , pp. 183-208
    • Liu, J.1    Zhou, J.2
  • 94
    • 12944273789 scopus 로고
    • PSP for the protection of the tumorous patients during chemotherapy
    • Yang, Q.;Kwok, C. Ed Hong Kong: Fudan University Press 1993
    • Shi, J. PSP for the protection of the tumorous patients during chemotherapy. In: Yang, Q.;Kwok, C. Ed. PSP International Symposium 1993. Hong Kong: Fudan University Press; 1993; pp. 271-272.
    • (1993) PSP International Symposium , pp. 271-272
    • Shi, J.1
  • 95
    • 0005609684 scopus 로고    scopus 로고
    • The curative effect of Yun Zhi polysaccharopeptide (PSP) on stomach cancer
    • Yang, Q. Ed Hong Kong: Hong Kong Association for Health Care Ltd
    • Wu, C.;Wu, J.;Sun, W. The curative effect of Yun Zhi polysaccharopeptide (PSP) on stomach cancer. In: Yang, Q. Ed. Advanced Research in PSP, 1999. Hong Kong: Hong Kong Association for Health Care Ltd; 1999; pp. 322-323.
    • (1999) Advanced Research in PSP, 1999 , pp. 322-323
    • Wu, C.1    Wu, J.2    Sun, W.3
  • 96
    • 0005569675 scopus 로고    scopus 로고
    • Prospective randomized trial of radiotherapy plus PSP in the treatment of esophageal carcinoma
    • Yang Q, ed Hong Kong: Hong Kong Association for Health Care Ltd
    • Yao W. Prospective randomized trial of radiotherapy plus PSP in the treatment of esophageal carcinoma. In: Yang Q, ed. Advanced Research in PSP, 1999. Hong Kong: Hong Kong Association for Health Care Ltd; 1999:310-313.
    • (1999) Advanced Research in PSP, 1999 , pp. 310-313
    • Yao, W.1
  • 97
    • 78049468390 scopus 로고    scopus 로고
    • A phase Ib/2, dose-escalating, safety, and efficacy study of imprime PGG, cetuximab and irinotecan in patients with advanced colorectal cancer (CRC)
    • abstr e15062
    • Tamayo, M.E.;Cornelio, G.H.;Bautista, J.B.;Flores, M.L.;Kurman, M.R.;Paul, M .M.;Gargano, M.A.;Patchen, M.L. A phase Ib/2, dose-escalating, safety, and efficacy study of imprime PGG, cetuximab and irinotecan in patients with advanced colorectal cancer (CRC). J Clin Oncol 27, 2009 (suppl; abstr e15062)
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Tamayo, M.E.1    Cornelio, G.H.2    Bautista, J.B.3    Flores, M.L.4    Kurman, M.R.5    Paul, M.M.6    Gargano, M.A.7    Patchen, M.L.8
  • 98
  • 101
    • 78049468390 scopus 로고    scopus 로고
    • A phase Ib/2, dose-escalating, safety, and efficacy study of imprime PGG, cetuximab and irinotecan in patients with advanced colorectal cancer (CRC)
    • (suppl; abstr e15062)
    • Tamayo, M.E.;Cornelio, G.H.;Bautista, J.B.;Flores, M.L.;Kurman, M.R.;Paul, M .M.;Gargano, M.A.;Patchen, M.L. A phase Ib/2, dose-escalating, safety, and efficacy study of imprime PGG, cetuximab and irinotecan in patients with advanced colorectal cancer (CRC). J Clin Oncol 27, 2009 (suppl; abstr e15062)
    • (2009) J Clin Oncol , vol.27
    • Tamayo, M.E.1    Cornelio, G.H.2    Bautista, J.B.3    Flores, M.L.4    Kurman, M.R.5    Paul, M.M.6    Gargano, M.A.7    Patchen, M.L.8
  • 102
    • 84889604241 scopus 로고    scopus 로고
    • A phase Ib/II, doseescalating, safety, and efficacy study of imprime PGG and cetuximab in patients with advanced colorectal cancer (CRC)
    • (suppl; abstr e14103)
    • Tamayo, M.E.;Cornelio, G.H.;Bautista, J.B.;Flores, M.L.;Tioleco, P.S.;Kurman, M.R.;Marsh, L.M.;Gargano, M.A.;Patchen, M.L. A phase Ib/II, doseescalating, safety, and efficacy study of imprime PGG and cetuximab in patients with advanced colorectal cancer (CRC). J Clin Oncol 28, 2010 (suppl; abstr e14103)
    • J Clin Oncol , vol.28 , pp. 2010
    • Tamayo, M.E.1    Cornelio, G.H.2    Bautista, J.B.3    Flores, M.L.4    Tioleco, P.S.5    Kurman, M.R.6    Marsh, L.M.7    Gargano, M.A.8    Patchen, M.L.9
  • 103
    • 84876302775 scopus 로고    scopus 로고
    • NIH ClinicalTrials.gov search of imprime PGG
    • NIH ClinicalTrials.gov search of imprime PGG http://clinicaltrials.gov/ ct2/results?term=imprime+PGG.
  • 105
    • 1242284232 scopus 로고    scopus 로고
    • Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro
    • Lin, H.; She, Y. H.; Cassileth, B. R.; Sirotnak, F.; Cunningham Rundles, S. Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro. Int Immunopharmacol, 2004, 4, 91-99.
    • (2004) Int Immunopharmacol , vol.4 , pp. 91-99
    • Lin, H.1    She, Y.H.2    Cassileth, B.R.3    Sirotnak, F.4    Cunningham Rundles, S.5


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