-
1
-
-
46149094611
-
Dehydroepiandrosterone, epiandrosterone and synthetic derivatives inhibit Junin virus replication in vitro
-
Acosta, E. G., et al. 2008. Dehydroepiandrosterone, epiandrosterone and synthetic derivatives inhibit Junin virus replication in vitro. Virus Res. 135: 203-212.
-
(2008)
Virus Res
, vol.135
, pp. 203-212
-
-
Acosta, E.G.1
-
2
-
-
50149100514
-
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis
-
Agudo, R., et al. 2008. Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. J. Mol. Biol. 382:652-666.
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 652-666
-
-
Agudo, R.1
-
3
-
-
77958122066
-
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape
-
Agudo, R., et al. 2010. A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. PLoS Pathog. 6(8):e1001072.
-
(2010)
PLoS Pathog
, vol.6
, Issue.8
-
-
Agudo, R.1
-
4
-
-
0023734872
-
Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus
-
Ahmed, R., et al. 1988. Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus. J. Virol. 62:3301-3308.
-
(1988)
J. Virol.
, vol.62
, pp. 3301-3308
-
-
Ahmed, R.1
-
5
-
-
0038722333
-
Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis
-
Airaksinen, A., N. Pariente, L. Menendez-Arias, and E. Domingo. 2003. Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis. Virology 311:339-349.
-
(2003)
Virology
, vol.311
, pp. 339-349
-
-
Airaksinen, A.1
Pariente, N.2
Menendez-Arias, L.3
Domingo, E.4
-
7
-
-
57349131683
-
Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin
-
Arias, A., et al. 2008. Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin. J. Virol. 82:12346-12355.
-
(2008)
J. Virol.
, vol.82
, pp. 12346-12355
-
-
Arias, A.1
-
8
-
-
24344467918
-
Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C
-
Asahina, Y., et al. 2005. Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C. J. Hepatol. 43:623-629.
-
(2005)
J. Hepatol.
, vol.43
, pp. 623-629
-
-
Asahina, Y.1
-
9
-
-
0030052809
-
Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen
-
Barton, L. L. 1996. Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen. Clin. Infect. Dis. 22:197.
-
(1996)
Clin. Infect. Dis.
, vol.22
, pp. 197
-
-
Barton, L.L.1
-
10
-
-
0030917156
-
Virus dynamics and drug therapy
-
Bonhoeffer, S., R. M. May, G. M. Shaw, and M. A. Nowak. 1997. Virus dynamics and drug therapy. Proc. Natl. Acad. Sci. U. S. A. 94:6971-6976.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 6971-6976
-
-
Bonhoeffer, S.1
May, R.M.2
Shaw, G.M.3
Nowak, M.A.4
-
11
-
-
0031297630
-
Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts
-
Bowen, M. D., C. J. Peters, and S. T. Nichol. 1997. Phylogenetic analysis of the Arenaviridae: patterns of virus evolution and evidence for cospeciation between arenaviruses and their rodent hosts. Mol. Phylogenet. Evol. 8:301-316.
-
(1997)
Mol. Phylogenet. Evol.
, vol.8
, pp. 301-316
-
-
Bowen, M.D.1
Peters, C.J.2
Nichol, S.T.3
-
12
-
-
67249156188
-
Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa
-
Briese, T., et al. 2009. Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa. PLoS Pathog. 5:e1000455.
-
(2009)
PLoS Pathog
, vol.5
-
-
Briese, T.1
-
13
-
-
34447299235
-
Arenaviridae: the viruses and their replication
-
D. M. Knipe and P. M. Howley (ed.), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA
-
Buchmeier, M. J., J. C. de la Torre, and C. J. Peters. 2007. Arenaviridae: the viruses and their replication, p. 1791-1827. In D. M. Knipe and P. M. Howley (ed.), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
-
(2007)
, pp. 1791-1827
-
-
Buchmeier, M.J.1
de la Torre, J.C.2
Peters, C.J.3
-
14
-
-
34447248532
-
Analysis of ribavirin mutagenicity in human hepatitis C virus infection
-
Chevaliez, S., R. Brillet, E. Lazaro, C. Hezode, and J. M. Pawlotsky. 2007. Analysis of ribavirin mutagenicity in human hepatitis C virus infection. J. Virol. 81:7732-7741.
-
(2007)
J. Virol.
, vol.81
, pp. 7732-7741
-
-
Chevaliez, S.1
Brillet, R.2
Lazaro, E.3
Hezode, C.4
Pawlotsky, J.M.5
-
15
-
-
0027469706
-
Safety, tolerance, and pharmacokinetics of systemic ribavirin in children with human immunodeficiency virus infection
-
Connor, E., et al. 1993. Safety, tolerance, and pharmacokinetics of systemic ribavirin in children with human immunodeficiency virus infection. Antimicrob. Agents Chemother. 37:532-539.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 532-539
-
-
Connor, E.1
-
16
-
-
0036333636
-
Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system
-
Contreras, A. M., et al. 2002. Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system. J. Virol. 76:8505-8517.
-
(2002)
J. Virol.
, vol.76
, pp. 8505-8517
-
-
Contreras, A.M.1
-
17
-
-
0035811016
-
RNA virus error catastrophe: direct molecular test by using ribavirin
-
Crotty, S., C. E. Cameron, and R. Andino. 2001. RNA virus error catastrophe: direct molecular test by using ribavirin. Proc. Natl. Acad. Sci. U. S. A. 98:6895-6900.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6895-6900
-
-
Crotty, S.1
Cameron, C.E.2
Andino, R.3
-
18
-
-
0034532953
-
The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen
-
Crotty, S., et al. 2000. The broad-spectrum antiviral ribonucleotide, ribavirin, is an RNA virus mutagen. Nat. Med. 6:1375-1379.
-
(2000)
Nat. Med.
, vol.6
, pp. 1375-1379
-
-
Crotty, S.1
-
19
-
-
36549028822
-
Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient
-
Cubero, M., et al. 2008. Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient. Virology 370:237-245.
-
(2008)
Virology
, vol.370
, pp. 237-245
-
-
Cubero, M.1
-
20
-
-
66149098217
-
Effect of ribavirin on the mutation rate and spectrum of hepatitis C virus in vivo
-
Cuevas, J. M., F. Gonzalez-Candelas, A. Moya, and R. Sanjuan. 2009. Effect of ribavirin on the mutation rate and spectrum of hepatitis C virus in vivo. J. Virol. 83:5760-5764.
-
(2009)
J. Virol.
, vol.83
, pp. 5760-5764
-
-
Cuevas, J.M.1
Gonzalez-Candelas, F.2
Moya, A.3
Sanjuan, R.4
-
21
-
-
0035835028
-
Interferon and ribavirin vs interferon alone in the re-treatment of chronic hepatitis C previously nonresponsive to interferon: a meta-analysis of randomized trials
-
Cummings, K. J., et al. 2001. Interferon and ribavirin vs interferon alone in the re-treatment of chronic hepatitis C previously nonresponsive to interferon: a meta-analysis of randomized trials. JAMA 285:193-199.
-
(2001)
JAMA
, vol.285
, pp. 193-199
-
-
Cummings, K.J.1
-
22
-
-
0032547944
-
Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group
-
Davis, G. L., et al. 1998. Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group. N. Engl. J. Med. 339:1493-1499.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1493-1499
-
-
Davis, G.L.1
-
23
-
-
0035120818
-
Combination of interferon and ribavirin in chronic hepatitis C: re-treatment of nonresponders to interferon
-
Di Bisceglie, A. M., J. Thompson, N. Smith-Wilkaitis, E. M. Brunt, and B. R. Bacon. 2001. Combination of interferon and ribavirin in chronic hepatitis C: re-treatment of nonresponders to interferon. Hepatology 33:704-707.
-
(2001)
Hepatology
, vol.33
, pp. 704-707
-
-
Di Bisceglie, A.M.1
Thompson, J.2
Smith-Wilkaitis, N.3
Brunt, E.M.4
Bacon, B.R.5
-
24
-
-
11844256382
-
Virus entry into error catastrophe as a new antiviral strategy
-
(ed.)
-
Domingo, E. (ed.). 2005. Virus entry into error catastrophe as a new antiviral strategy. Virus Res. 107:115-228.
-
(2005)
Virus Res
, vol.107
, pp. 115-228
-
-
Domingo, E.1
-
25
-
-
42149127046
-
Ribavirin considerations in treatment optimization
-
Dusheiko, G., D. Nelson, and K. R. Reddy. 2008. Ribavirin considerations in treatment optimization. Antivir. Ther. 13(Suppl. 1):23-30.
-
(2008)
Antivir. Ther.
, vol.13
, Issue.SUPPL. 1
, pp. 23-30
-
-
Dusheiko, G.1
Nelson, D.2
Reddy, K.R.3
-
26
-
-
0020960565
-
Genomic and biologic variation among commonly used lymphocytic choriomeningitis virus strains
-
Dutko, F. J., and M. B. A. Oldstone. 1983. Genomic and biologic variation among commonly used lymphocytic choriomeningitis virus strains. J. Gen. Virol. 64:1689-1694.
-
(1983)
J. Gen. Virol.
, vol.64
, pp. 1689-1694
-
-
Dutko, F.J.1
Oldstone, M.B.A.2
-
27
-
-
33745465779
-
Phylogeny and evolution of old world arenaviruses
-
Emonet, S., J. J. Lemasson, J. P. Gonzalez, X. de Lamballerie, and R. N. Charrel. 2006. Phylogeny and evolution of old world arenaviruses. Virology 350:251-257.
-
(2006)
Virology
, vol.350
, pp. 251-257
-
-
Emonet, S.1
Lemasson, J.J.2
Gonzalez, J.P.3
de Lamballerie, X.4
Charrel, R.N.5
-
28
-
-
68649123335
-
Arenavirus genetic diversity and its biological implications
-
Emonet, S. F., J. C. de la Torre, E. Domingo, and N. Sevilla. 2009. Arenavirus genetic diversity and its biological implications. Infect. Genet. Evol. 9:417-429.
-
(2009)
Infect. Genet. Evol.
, vol.9
, pp. 417-429
-
-
Emonet, S.F.1
de la Torre, J.C.2
Domingo, E.3
Sevilla, N.4
-
29
-
-
0028157870
-
Antiviral treatment of Argentine hemorrhagic fever
-
Enria, D. A., and J. I. Maiztegui. 1994. Antiviral treatment of Argentine hemorrhagic fever. Antiviral Res. 23:23-31.
-
(1994)
Antiviral Res
, vol.23
, pp. 23-31
-
-
Enria, D.A.1
Maiztegui, J.I.2
-
30
-
-
77952710653
-
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
-
Ferrer-Orta, C., et al. 2010. Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J. Virol. 84:6188-6199.
-
(2010)
J. Virol.
, vol.84
, pp. 6188-6199
-
-
Ferrer-Orta, C.1
-
31
-
-
33646875293
-
Transmission of lymphocytic choriomeningitis virus by organ transplantation
-
Fischer, S. A., et al. 2006. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N. Engl. J. Med. 354:2235-2249.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2235-2249
-
-
Fischer, S.A.1
-
32
-
-
78649469072
-
Lethal mutagenesis: targeting the mutator phenotype in cancer
-
Fox, E. J., and L. A. Loeb. 2010. Lethal mutagenesis: targeting the mutator phenotype in cancer. Semin. Cancer Biol. 20:353-359.
-
(2010)
Semin. Cancer Biol.
, vol.20
, pp. 353-359
-
-
Fox, E.J.1
Loeb, L.A.2
-
33
-
-
0014546166
-
The inhibition of nucleic acid synthesis by mycophenolic acid
-
Franklin, T. J., and J. M. Cook. 1969. The inhibition of nucleic acid synthesis by mycophenolic acid. Biochem. J. 113:515-524.
-
(1969)
Biochem. J.
, vol.113
, pp. 515-524
-
-
Franklin, T.J.1
Cook, J.M.2
-
34
-
-
1842510032
-
Preextinction viral RNA can interfere with infectivity
-
González-López, C., A. Arias, N. Pariente, G. Gómez-Mariano, and E. Domingo. 2004. Preextinction viral RNA can interfere with infectivity. J. Virol. 78:3319-3324.
-
(2004)
J. Virol.
, vol.78
, pp. 3319-3324
-
-
González-López, C.1
Arias, A.2
Pariente, N.3
Gómez-Mariano, G.4
Domingo, E.5
-
35
-
-
25144524546
-
Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe
-
González-López, C., G. Gómez-Mariano, C. Escarmís, and E. Domingo. 2005. Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infect. Genet. Evol. 5:366-374.
-
(2005)
Infect. Genet. Evol.
, vol.5
, pp. 366-374
-
-
González-López, C.1
Gómez-Mariano, G.2
Escarmís, C.3
Domingo, E.4
-
36
-
-
56649102052
-
Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin
-
Gowen, B. B., et al. 2008. Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. PLoS One 3:e3725.
-
(2008)
PLoS One
, vol.3
-
-
Gowen, B.B.1
-
37
-
-
31144445870
-
Mechanisms of action of ribavirin against distinct viruses
-
Graci, J. D., and C. E. Cameron. 2006. Mechanisms of action of ribavirin against distinct viruses. Rev. Med. Virol. 16:37-48.
-
(2006)
Rev. Med. Virol.
, vol.16
, pp. 37-48
-
-
Graci, J.D.1
Cameron, C.E.2
-
38
-
-
70350132524
-
Therapeutically targeting RNA viruses via lethal mutagenesis
-
Graci, J. D., and C. E. Cameron. 2008. Therapeutically targeting RNA viruses via lethal mutagenesis. Future Virol. 3:553-566.
-
(2008)
Future Virol
, vol.3
, pp. 553-566
-
-
Graci, J.D.1
Cameron, C.E.2
-
39
-
-
23244443638
-
Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence
-
Grande-Pérez, A., G. Gómez-Mariano, P. R. Lowenstein, and E. Domingo. 2005. Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. J. Virol. 79:10451-10459.
-
(2005)
J. Virol.
, vol.79
, pp. 10451-10459
-
-
Grande-Pérez, A.1
Gómez-Mariano, G.2
Lowenstein, P.R.3
Domingo, E.4
-
40
-
-
15444379112
-
Suppression of viral infectivity through lethal defection
-
Grande-Pérez, A., E. Lazaro, P. Lowenstein, E. Domingo, and S. C. Manrubia. 2005. Suppression of viral infectivity through lethal defection. Proc. Natl. Acad. Sci. U. S. A. 102:4448-4452.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 4448-4452
-
-
Grande-Pérez, A.1
Lazaro, E.2
Lowenstein, P.3
Domingo, E.4
Manrubia, S.C.5
-
41
-
-
0036789885
-
Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity
-
Grande-Pérez, A., S. Sierra, M. G. Castro, E. Domingo, and P. R. Lowenstein. 2002. Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity. Proc. Natl. Acad. Sci. U. S. A. 99:12938-12943.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 12938-12943
-
-
Grande-Pérez, A.1
Sierra, S.2
Castro, M.G.3
Domingo, E.4
Lowenstein, P.R.5
-
42
-
-
76549118168
-
Stochastic extinction of viral infectivity through the action of defectors
-
Iranzo, J., and S. C. Manrubia. 2009. Stochastic extinction of viral infectivity through the action of defectors. Europhys. Lett. 85:18001.
-
(2009)
Europhys. Lett.
, vol.85
, pp. 18001
-
-
Iranzo, J.1
Manrubia, S.C.2
-
43
-
-
0018897060
-
Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin
-
Jahrling, P. B., et al. 1980. Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin. J. Infect. Dis. 141:580-589.
-
(1980)
J. Infect. Dis.
, vol.141
, pp. 580-589
-
-
Jahrling, P.B.1
-
44
-
-
0021339525
-
Enhanced treatment of Lassa fever by immune plasma combined with ribavirin in cynomolgus monkeys
-
Jahrling, P. B., C. J. Peters, and E. L. Stephen. 1984. Enhanced treatment of Lassa fever by immune plasma combined with ribavirin in cynomolgus monkeys. J. Infect. Dis. 149:420-427.
-
(1984)
J. Infect. Dis.
, vol.149
, pp. 420-427
-
-
Jahrling, P.B.1
Peters, C.J.2
Stephen, E.L.3
-
45
-
-
33646770959
-
Lymphocytic choriomeningitis virus: an emerging obstetric pathogen?
-
Jamieson, D. J., A. P. Kourtis, M. Bell, and S. A. Rasmussen. 2006. Lymphocytic choriomeningitis virus: an emerging obstetric pathogen? Am. J. Obstet. Gynecol. 194:1532-1536.
-
(2006)
Am J. Obstet. Gynecol.
, vol.194
, pp. 1532-1536
-
-
Jamieson, D.J.1
Kourtis, A.P.2
Bell, M.3
Rasmussen, S.A.4
-
46
-
-
48749086685
-
Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naive populations and associate with reduced treatment efficacy
-
Johnson, J. A., et al. 2008. Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naive populations and associate with reduced treatment efficacy. PLoS Med. 5:e158.
-
(2008)
PLoS Med
, vol.5
-
-
Johnson, J.A.1
-
47
-
-
0033805382
-
Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells
-
Jordan, I., T. Briese, N. Fischer, J. Y. Lau, and W. I. Lipkin. 2000. Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells. J. Infect. Dis. 182:1214-1217.
-
(2000)
J. Infect. Dis.
, vol.182
, pp. 1214-1217
-
-
Jordan, I.1
Briese, T.2
Fischer, N.3
Lau, J.Y.4
Lipkin, W.I.5
-
48
-
-
8444233615
-
Inhibition of subgenomic hepatitis C virus RNA in Huh-7 cells: ribavirin induces mutagenesis in HCV RNA
-
Kanda, T., et al. 2004. Inhibition of subgenomic hepatitis C virus RNA in Huh-7 cells: ribavirin induces mutagenesis in HCV RNA. J. Viral. Hepat. 11:479-487.
-
(2004)
J. Viral. Hepat.
, vol.11
, pp. 479-487
-
-
Kanda, T.1
-
49
-
-
0022598396
-
Effect of ribavirin and tributylribavirin on Argentine hemorrhagic fever (Junin virus) in guinea pigs
-
Kenyon, R. H., P. G. Canonico, D. E. Green, and C. J. Peters. 1986. Effect of ribavirin and tributylribavirin on Argentine hemorrhagic fever (Junin virus) in guinea pigs. Antimicrob. Agents Chemother. 29:521-523.
-
(1986)
Antimicrob. Agents Chemother.
, vol.29
, pp. 521-523
-
-
Kenyon, R.H.1
Canonico, P.G.2
Green, D.E.3
Peters, C.J.4
-
50
-
-
0023627616
-
Ribavirin induced differentiation of murine erythroleukemia cells
-
Kerr, S. J. 1987. Ribavirin induced differentiation of murine erythroleukemia cells. Mol. Cell. Biochem. 77:187-194.
-
(1987)
Mol. Cell. Biochem.
, vol.77
, pp. 187-194
-
-
Kerr, S.J.1
-
51
-
-
0030935067
-
Treatment of Bolivian hemorrhagic fever with intravenous ribavirin
-
Kilgore, P. E., et al. 1997. Treatment of Bolivian hemorrhagic fever with intravenous ribavirin. Clin. Infect. Dis. 24:718-722.
-
(1997)
Clin. Infect. Dis.
, vol.24
, pp. 718-722
-
-
Kilgore, P.E.1
-
52
-
-
58149388300
-
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients
-
Kuntzen, T., et al. 2008. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naive patients. Hepatology 48:1769-1778.
-
(2008)
Hepatology
, vol.48
, pp. 1769-1778
-
-
Kuntzen, T.1
-
53
-
-
0028489042
-
International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability
-
Kunz, B. A., et al. 1994. International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability. Mutat. Res. 318:1-64.
-
(1994)
Mutat. Res.
, vol.318
, pp. 1-64
-
-
Kunz, B.A.1
-
54
-
-
0034864550
-
Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes
-
Lanford, R. E., et al. 2001. Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. J. Virol. 75:8074-8081.
-
(2001)
J. Virol.
, vol.75
, pp. 8074-8081
-
-
Lanford, R.E.1
-
55
-
-
38949217075
-
Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers
-
Lee, A. M., et al. 2008. Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers. Virology 372:107-117.
-
(2008)
Virology
, vol.372
, pp. 107-117
-
-
Lee, A.M.1
-
56
-
-
0037016424
-
Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen
-
Le Moing, V., et al. 2002. Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen. AIDS 16:21-29.
-
(2002)
AIDS
, vol.16
, pp. 21-29
-
-
Le Moing, V.1
-
57
-
-
13744258758
-
The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
-
Leyssen, P., J. Balzarini, E. De Clercq, and J. Neyts. 2005. The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase. J. Virol. 79:1943-1947.
-
(2005)
J. Virol.
, vol.79
, pp. 1943-1947
-
-
Leyssen, P.1
Balzarini, J.2
De Clercq, E.3
Neyts, J.4
-
58
-
-
40849126566
-
Molecular strategies to inhibit the replication of RNA viruses
-
Leyssen, P., E. De Clercq, and J. Neyts. 2008. Molecular strategies to inhibit the replication of RNA viruses. Antiviral Res. 78:9-25.
-
(2008)
Antiviral Res
, vol.78
, pp. 9-25
-
-
Leyssen, P.1
De Clercq, E.2
Neyts, J.3
-
59
-
-
33645102511
-
The anti-yellow fever virus activity of ribavirin is independent of error-prone replication
-
Leyssen, P., E. De Clercq, and J. Neyts. 2006. The anti-yellow fever virus activity of ribavirin is independent of error-prone replication. Mol. Pharmacol. 69:1461-1467.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1461-1467
-
-
Leyssen, P.1
De Clercq, E.2
Neyts, J.3
-
60
-
-
0024791803
-
Arenavirus infection in the guinea pig model: antiviral therapy with recombinant interferon-alpha, the immunomodulator CL246, 738 and ribavirin
-
Lucia, H. L., D. H. Coppenhaver, and S. Baron. 1989. Arenavirus infection in the guinea pig model: antiviral therapy with recombinant interferon-alpha, the immunomodulator CL246,738 and ribavirin. Antiviral Res. 12:279-292.
-
(1989)
Antiviral Res
, vol.12
, pp. 279-292
-
-
Lucia, H.L.1
Coppenhaver, D.H.2
Baron, S.3
-
61
-
-
34247552260
-
Mutation rate of the hepatitis C virus NS5B in patients undergoing treatment with ribavirin monotherapy
-
Lutchman, G., et al. 2007. Mutation rate of the hepatitis C virus NS5B in patients undergoing treatment with ribavirin monotherapy. Gastroenterology 132:1757-1766.
-
(2007)
Gastroenterology
, vol.132
, pp. 1757-1766
-
-
Lutchman, G.1
-
62
-
-
0035824671
-
Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin
-
Maag, D., C. Castro, Z. Hong, and C. E. Cameron. 2001. Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin. J. Biol. Chem. 276:46094-46098.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46094-46098
-
-
Maag, D.1
Castro, C.2
Hong, Z.3
Cameron, C.E.4
-
63
-
-
77949527717
-
An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis
-
Martin, V., D. Abia, E. Domingo, and A. Grande-Perez. 2010. An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis. J. Gen. Virol. 91:990-1003.
-
(2010)
J. Gen. Virol.
, vol.91
, pp. 990-1003
-
-
Martin, V.1
Abia, D.2
Domingo, E.3
Grande-Perez, A.4
-
64
-
-
47749097091
-
No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus
-
Martín, V., A. Grande-Pérez, and E. Domingo. 2008. No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus. Virology 378:185-192.
-
(2008)
Virology
, vol.378
, pp. 185-192
-
-
Martín, V.1
Grande-Pérez, A.2
Domingo, E.3
-
65
-
-
0027946446
-
Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations
-
Martínez, M. A., J. P. Vartanian, and S. Wain-Hobson. 1994. Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations. Proc. Natl. Acad. Sci. U. S. A. 91:11787-11791.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 11787-11791
-
-
Martínez, M.A.1
Vartanian, J.P.2
Wain-Hobson, S.3
-
66
-
-
0022630892
-
Lassa fever. Effective therapy with ribavirin
-
McCormick, J. B., et al. 1986. Lassa fever. Effective therapy with ribavirin. N. Engl. J. Med. 314:20-26.
-
(1986)
N. Engl. J. Med.
, vol.314
, pp. 20-26
-
-
McCormick, J.B.1
-
67
-
-
0032547938
-
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group
-
McHutchison, J. G., et al. 1998. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N. Engl. J. Med. 339:1485-1492.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1485-1492
-
-
McHutchison, J.G.1
-
68
-
-
78751692774
-
T-705 (favipiravir) inhibition of arenavirus replication in cell culture
-
Mendenhall, M., et al. 2011. T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrob. Agents Chemother. 55:782-787.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 782-787
-
-
Mendenhall, M.1
-
69
-
-
37849012228
-
Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity
-
Moriyama, K., et al. 2008. Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity. J. Med. Chem. 51:159-166.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 159-166
-
-
Moriyama, K.1
-
70
-
-
84884754100
-
Intra-host dynamics and evolution of HIV infections
-
E. Domingo, C. R. Parrish, and J. J. Holland (ed.), 2nd ed. Academic Press, London, United Kingdom
-
Müller, V., and S. Bonhoeffer. 2008. Intra-host dynamics and evolution of HIV infections, p. 279-302. In E. Domingo, C. R. Parrish, and J. J. Holland (ed.), Origin and evolution of viruses, 2nd ed. Academic Press, London, United Kingdom.
-
(2008)
Origin and evolution of viruses
, pp. 279-302
-
-
Müller, V.1
Bonhoeffer, S.2
-
71
-
-
61549139113
-
Antiviral resistance and impact on viral replication capacity: evolution of viruses under antiviral pressure occurs in three phases
-
Nijhuis, M., N. M. van Maarseveen, and C. A. Boucher. 2009. Antiviral resistance and impact on viral replication capacity: evolution of viruses under antiviral pressure occurs in three phases. Handb. Exp. Pharmacol. 189:299-320.
-
(2009)
Handb. Exp. Pharmacol.
, vol.189
, pp. 299-320
-
-
Nijhuis, M.1
van Maarseveen, N.M.2
Boucher, C.A.3
-
74
-
-
40449115382
-
A new arenavirus in a cluster of fatal transplantassociated diseases
-
Palacios, G., et al. 2008. A new arenavirus in a cluster of fatal transplantassociated diseases. N. Engl. J. Med. 358:991-998.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 991-998
-
-
Palacios, G.1
-
75
-
-
0038278911
-
Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus
-
Pariente, N., A. Airaksinen, and E. Domingo. 2003. Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. J. Virol. 77:7131-7138.
-
(2003)
J. Virol.
, vol.77
, pp. 7131-7138
-
-
Pariente, N.1
Airaksinen, A.2
Domingo, E.3
-
76
-
-
11844282166
-
Metabolism and antiviral activity of ribavirin
-
Parker, W. B. 2005. Metabolism and antiviral activity of ribavirin. Virus Res. 107:165-171.
-
(2005)
Virus Res
, vol.107
, pp. 165-171
-
-
Parker, W.B.1
-
77
-
-
79952008955
-
Influence of mutagenesis and viral load in sustained, low-level replication of an RNA virus
-
Perales, C., R. Agudo, S. C. Manrubia, and E. Domingo. 2011. Influence of mutagenesis and viral load in sustained, low-level replication of an RNA virus. J. Mol. Biol. 407:60-78.
-
(2011)
J. Mol. Biol.
, vol.407
, pp. 60-78
-
-
Perales, C.1
Agudo, R.2
Manrubia, S.C.3
Domingo, E.4
-
78
-
-
73549116556
-
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections
-
Perales, C., R. Agudo, H. Tejero, S. C. Manrubia, and E. Domingo. 2009. Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. PLoS Pathog. 5:e1000658.
-
(2009)
PLoS Pathog
, vol.5
-
-
Perales, C.1
Agudo, R.2
Tejero, H.3
Manrubia, S.C.4
Domingo, E.5
-
79
-
-
34247607729
-
Ribavirin: is it a mutagen for hepatitis C virus?
-
Perelson, A. S., and T. J. Layden. 2007. Ribavirin: is it a mutagen for hepatitis C virus? Gastroenterology 132:2050-2052.
-
(2007)
Gastroenterology
, vol.132
, pp. 2050-2052
-
-
Perelson, A.S.1
Layden, T.J.2
-
80
-
-
13444310882
-
Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA
-
Pfeiffer, J. K., and K. Kirkegaard. 2005. Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA. J. Virol. 79:2346-2355.
-
(2005)
J. Virol.
, vol.79
, pp. 2346-2355
-
-
Pfeiffer, J.K.1
Kirkegaard, K.2
-
81
-
-
0017100246
-
Homologous interference of lymphocytic choriomeningitis virus: detection and measurement of interference focus-forming units
-
Popescu, M., H. Schaefer, and F. Lehmann-Grube. 1976. Homologous interference of lymphocytic choriomeningitis virus: detection and measurement of interference focus-forming units. J. Virol. 20:1-8.
-
(1976)
J. Virol.
, vol.20
, pp. 1-8
-
-
Popescu, M.1
Schaefer, H.2
Lehmann-Grube, F.3
-
82
-
-
0345578679
-
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)
-
Ruiz-Jarabo, C. M., C. Ly, E. Domingo, and J. C. de la Torre. 2003. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology 308:37-47.
-
(2003)
Virology
, vol.308
, pp. 37-47
-
-
Ruiz-Jarabo, C.M.1
Ly, C.2
Domingo, E.3
de la Torre, J.C.4
-
83
-
-
0242300045
-
Evidence for quasispecies distributions in the human hepatitis A virus genome
-
Sánchez, G., A. Bosch, G. Gómez-Mariano, E. Domingo, and R. Pinto. 2003. Evidence for quasispecies distributions in the human hepatitis A virus genome. Virology 315:34-42.
-
(2003)
Virology
, vol.315
, pp. 34-42
-
-
Sánchez, G.1
Bosch, A.2
Gómez-Mariano, G.3
Domingo, E.4
Pinto, R.5
-
84
-
-
18244389013
-
Monitoring of clinical and laboratory data in two cases of imported Lassa fever
-
Schmitz, H., et al. 2002. Monitoring of clinical and laboratory data in two cases of imported Lassa fever. Microbes Infect. 4:43-50.
-
(2002)
Microbes Infect
, vol.4
, pp. 43-50
-
-
Schmitz, H.1
-
85
-
-
0037213579
-
Ribavirin causes error catastrophe during Hantaan virus replication
-
Severson, W. E., C. S. Schmaljohn, A. Javadian, and C. B. Jonsson. 2003. Ribavirin causes error catastrophe during Hantaan virus replication. J. Virol. 77:481-488.
-
(2003)
J. Virol.
, vol.77
, pp. 481-488
-
-
Severson, W.E.1
Schmaljohn, C.S.2
Javadian, A.3
Jonsson, C.B.4
-
86
-
-
30644470969
-
Arenavirus diversity and evolution: quasispecies in vivo
-
Sevilla, N., and J. C. de la Torre. 2006. Arenavirus diversity and evolution: quasispecies in vivo. Curr. Top. Microbiol. Immunol. 299:315-335.
-
(2006)
Curr. Top. Microbiol. Immunol.
, vol.299
, pp. 315-335
-
-
Sevilla, N.1
de la Torre, J.C.2
-
87
-
-
0009502225
-
Antiviral activity of virazole: review and structure-activity relationships
-
Sidwell, O. W., L. N. Simon, J. T. Witkowski, and R. K. Robins. 1974. Antiviral activity of virazole: review and structure-activity relationships. Prog. Chemother. 2:889-903.
-
(1974)
Prog. Chemother.
, vol.2
, pp. 889-903
-
-
Sidwell, O.W.1
Simon, L.N.2
Witkowski, J.T.3
Robins, R.K.4
-
88
-
-
33846813925
-
Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe
-
Sierra, M., et al. 2007. Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe. J. Virol. 81:2012-2024.
-
(2007)
J. Virol.
, vol.81
, pp. 2012-2024
-
-
Sierra, M.1
-
89
-
-
0027475323
-
Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen
-
Smee, D. F., et al. 1993. Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral Res. 20:57-70.
-
(1993)
Antiviral Res
, vol.20
, pp. 57-70
-
-
Smee, D.F.1
-
90
-
-
0003921711
-
-
Academic Press, Inc., New York, NY
-
Smith, R. A., and W. Kirkpatrick. 1980. Ribavirin: a broad spectrum antiviral agent. Academic Press, Inc., New York, NY.
-
(1980)
Ribavirin: a broad spectrum antiviral agent
-
-
Smith, R.A.1
Kirkpatrick, W.2
-
91
-
-
0034864547
-
Ribavirin-current status of a broad spectrum antiviral agent
-
Snell, N. J. 2001. Ribavirin-current status of a broad spectrum antiviral agent. Expert Opin. Pharmacother. 2:1317-1324.
-
(2001)
Expert Opin. Pharmacother.
, vol.2
, pp. 1317-1324
-
-
Snell, N.J.1
-
92
-
-
0015609404
-
Mechanism of action of 1-β-D-ribofuranosyl1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent
-
Streeter, D. G., et al. 1973. Mechanism of action of 1-β-D-ribofuranosyl1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent. Proc. Natl. Acad. Sci. U. S. A. 70:1174-1178.
-
(1973)
Proc. Natl. Acad. Sci. U. S. A.
, vol.70
, pp. 1174-1178
-
-
Streeter, D.G.1
-
93
-
-
20644470543
-
Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection
-
Tapia, N., et al. 2005. Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. Virology 338:1-8.
-
(2005)
Virology
, vol.338
, pp. 1-8
-
-
Tapia, N.1
-
94
-
-
0036253039
-
Initiation of HAART in drug-naive HIV type 1 patients prevents viral breakthrough for a median period of 35.5 months in 60% of the patients
-
Van Vaerenbergh, K., et al. 2002. Initiation of HAART in drug-naive HIV type 1 patients prevents viral breakthrough for a median period of 35.5 months in 60% of the patients. AIDS Res. Hum. Retroviruses 18:419-426.
-
(2002)
AIDS Res. Hum. Retroviruses
, vol.18
, pp. 419-426
-
-
Van Vaerenbergh, K.1
-
96
-
-
0016619531
-
A comparison of biochemical and biological properties of standard and defective lymphocytic choriomeningitis virus
-
Welsh, R. M., et al. 1975. A comparison of biochemical and biological properties of standard and defective lymphocytic choriomeningitis virus. Bull. World Health Organ. 52:403-408.
-
(1975)
Bull. World Health Organ.
, vol.52
, pp. 403-408
-
-
Welsh, R.M.1
-
97
-
-
0015463991
-
Properties of defective lymphocytic choriomeningitis virus
-
Welsh, R. M., C. M. O'Connell, and C. J. Pfau. 1972. Properties of defective lymphocytic choriomeningitis virus. J. Gen. Virol. 17:355-359.
-
(1972)
J. Gen. Virol.
, vol.17
, pp. 355-359
-
-
Welsh, R.M.1
O'Connell, C.M.2
Pfau, C.J.3
-
98
-
-
85047692907
-
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA
-
Zhou, S., R. Liu, B. M. Baroudy, B. A. Malcolm, and G. R. Reyes. 2003. The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA. Virology 310:333-342.
-
(2003)
Virology
, vol.310
, pp. 333-342
-
-
Zhou, S.1
Liu, R.2
Baroudy, B.M.3
Malcolm, B.A.4
Reyes, G.R.5
-
99
-
-
0017879637
-
Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5'-triphosphates in human blood and L5178Y cells
-
Zimmerman, T. P., and R. D. Deeprose. 1978. Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5'-triphosphates in human blood and L5178Y cells. Biochem. Pharmacol. 27:709-716.
-
(1978)
Biochem. Pharmacol.
, vol.27
, pp. 709-716
-
-
Zimmerman, T.P.1
Deeprose, R.D.2
|