Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242

Virology

Volumn 423, Issue 1, 2012, Pages 14-22

  Pasquato, Antonella ^a   Rochat, Cylia ^a   Burri, Dominique J ^a   Pasqual, Giulia ^a   La Torre, Juan Carlos de ^b   Kunz, Stefan ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Anti viral; Arenavirus; Glycoprotein; Inhibitor; Protease

Indexed keywords

(4 [(DIETHYLAMINO)METHYL] N [2 (2 METHOXYPHENYL)ETHYL] N [PYRROLIDIN 3 YL] [BENZAMIDE DIHYDROCHLORIDE]); ACTIVATING TRANSCRIPTION FACTOR 6; HEAT SHOCK PROTEIN; ISOENZYME; KEXIN; PF 429242; PROTEINASE INHIBITOR; RIBAVIRIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; SUBTILISIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARENAVIRUS; ARENAVIRUS INFECTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; UPREGULATION;

AMINO ACID SEQUENCE; ARENAVIRIDAE INFECTIONS; ARENAVIRUSES, OLD WORLD; BASE SEQUENCE; CELL LINE; ENZYME INHIBITORS; HUMANS; MOLECULAR SEQUENCE DATA; PROPROTEIN CONVERTASES; PYRROLIDINES; SERINE ENDOPEPTIDASES;

ARENAVIRUS; NEW WORLD ARENAVIRUSES; OLD WORLD ARENAVIRUSES;

EID: 84855341533     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.11.008     Document Type: Article

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