Evaluation of drug-induced injury and human response in precision-cut tissue slices

Xenobiotica

Volumn 43, Issue 1, 2013, Pages 29-40

  Vickers, Alison E M ^a   Fisher, Robyn L ^b  

^a ALLERGAN INC   (United States)

^b Vitron Inc   (United States)

Author keywords

Human tissue slices

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CISPLATIN; CYCLOSPORIN A; CYTOCHROME P450 3A4; DANTROLENE; DICLOFENAC; GLUTATHIONE; PARACETAMOL; REACTIVE OXYGEN METABOLITE; THIAMAZOLE; THYROID PEROXIDASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD TOXICITY; CELL INTERACTION; CHOLESTASIS; DRUG INDUCED DISEASE; DRUG METABOLISM; DRUG SAFETY; EVALUATION; EXTRACELLULAR MATRIX; FATTY LIVER; FIRST PASS EFFECT; GENE EXPRESSION PROFILING; HEMOLYSIS; HUMAN; HUMAN TISSUE; KIDNEY INJURY; LIVER DYSFUNCTION; LIVER FUNCTION; LIVER INJURY; LIVER TOXICITY; MEASUREMENT; MITOCHONDRIAL TOXICITY; MORPHOLOGY; NEPHROSIS; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRECISION CUT TISSUE SLICE; PROTEIN EXPRESSION; REVIEW; RISK ASSESSMENT; SIDE EFFECT; TISSUE SLICE;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; CELL COMMUNICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOXICITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; ORGAN CULTURE TECHNIQUES;

ANIMALIA;

EID: 84870525273     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2012.732714     Document Type: Review

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