-
1
-
-
78349284844
-
Aspects of TNF inhibitor therapy in rheumatoid arthritis
-
J. Nam, and P. Emery Aspects of TNF inhibitor therapy in rheumatoid arthritis Mod Rheumatol. 20 4 2010 325 330
-
(2010)
Mod Rheumatol.
, vol.20
, Issue.4
, pp. 325-330
-
-
Nam, J.1
Emery, P.2
-
2
-
-
34249720998
-
Cytokines in the pathogenesis of rheumatoid arthritis
-
I.B. McInnes, and G. Schett Cytokines in the pathogenesis of rheumatoid arthritis Nat. Rev. Immunol. 7 6 2007 429 442
-
(2007)
Nat. Rev. Immunol.
, vol.7
, Issue.6
, pp. 429-442
-
-
McInnes, I.B.1
Schett, G.2
-
3
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
T. Bongartz, A.J. Sutton, M.J. Sweeting, I. Buchan, E.L. Matteson, and V. Montori Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials JAMA 17 295 19 2006 2275 2285
-
(2006)
JAMA 17
, vol.295
, Issue.19
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
4
-
-
40549146541
-
Tumor necrosis factor inhibition: A part of the solution or a part of the problem of heart failure in rheumatoid arthritis?
-
S.E. Gabriel Tumor necrosis factor inhibition: a part of the solution or a part of the problem of heart failure in rheumatoid arthritis? Arthritis Rheum. 58 3 2008 637 640
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.3
, pp. 637-640
-
-
Gabriel, S.E.1
-
5
-
-
17244378648
-
Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis
-
R.M. Schiffelers, J. Xu, G. Storm, M.C. Woodle, and P.V. Scaria Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis Arthritis Rheum. 52 4 2005 1314 1318
-
(2005)
Arthritis Rheum.
, vol.52
, Issue.4
, pp. 1314-1318
-
-
Schiffelers, R.M.1
Xu, J.2
Storm, G.3
Woodle, M.C.4
Scaria, P.V.5
-
6
-
-
25144444898
-
Electro-transfer of small interfering RNA ameliorated arthritis in rats
-
A. Inoue, K.A. Takahashi, O. Mazda, R. Terauchi, Y. Arai, T. Kishida, M. Shin-Ya, H. Asada, T. Morihara, H. Tonomura, S. Ohashi, Y. Kajikawa, Y. Kawahito, J. Imanishi, M. Kawata, and T. Kubo Electro-transfer of small interfering RNA ameliorated arthritis in rats Biochem. Biophys. Res. Commun. 336 3 2005 903 908
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, Issue.3
, pp. 903-908
-
-
Inoue, A.1
Takahashi, K.A.2
Mazda, O.3
Terauchi, R.4
Arai, Y.5
Kishida, T.6
Shin-Ya, M.7
Asada, H.8
Morihara, T.9
Tonomura, H.10
Ohashi, S.11
Kajikawa, Y.12
Kawahito, Y.13
Imanishi, J.14
Kawata, M.15
Kubo, T.16
-
7
-
-
58149215702
-
Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
-
K.A. Howard, S.R. Paludan, M.A. Behlke, F. Besenbacher, B. Deleuran, and J. Kjems Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model Mol. Ther. 17 1 2009 162 168
-
(2009)
Mol. Ther.
, vol.17
, Issue.1
, pp. 162-168
-
-
Howard, K.A.1
Paludan, S.R.2
Behlke, M.A.3
Besenbacher, F.4
Deleuran, B.5
Kjems, J.6
-
8
-
-
33745014998
-
Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis
-
M. Khoury, P. Louis-Plence, V. Escriou, D. Noel, C. Largeau, C. Cantos, D. Scherman, C. Jorgensen, and F. Apparailly Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis Arthritis Rheum. 54 6 2006 1867 1877
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.6
, pp. 1867-1877
-
-
Khoury, M.1
Louis-Plence, P.2
Escriou, V.3
Noel, D.4
Largeau, C.5
Cantos, C.6
Scherman, D.7
Jorgensen, C.8
Apparailly, F.9
-
9
-
-
78649722174
-
Comprehensive analysis of sequence-specific stability of siRNA
-
J. Hong, Y. Huang, J. Li, F. Yi, J. Zheng, H. Huang, N. Wei, Y. Shan, M. An, H. Zhang, J. Ji, P. Zhang, Z. Xi, Q. Du, and Z. Liang Comprehensive analysis of sequence-specific stability of siRNA FASEB J. 24 12 2010 4844 4855
-
(2010)
FASEB J.
, vol.24
, Issue.12
, pp. 4844-4855
-
-
Hong, J.1
Huang, Y.2
Li, J.3
Yi, F.4
Zheng, J.5
Huang, H.6
Wei, N.7
Shan, Y.8
An, M.9
Zhang, H.10
Ji, J.11
Zhang, P.12
Xi, Z.13
Du, Q.14
Liang, Z.15
-
10
-
-
67649094527
-
RNA interference-based gene therapy for successful treatment of rheumatoid arthritis
-
G. Courties, J. Presumey, I. Duroux-Richard, C. Jorgensen, and F. Apparailly RNA interference-based gene therapy for successful treatment of rheumatoid arthritis Expert Opin. Biol. Ther. 9 5 2009 535 538
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, Issue.5
, pp. 535-538
-
-
Courties, G.1
Presumey, J.2
Duroux-Richard, I.3
Jorgensen, C.4
Apparailly, F.5
-
11
-
-
0343247711
-
Biodegradation and biocompatibility of PLA and PLGA microspheres
-
J.M. Anderson, and M.S. Shive Biodegradation and biocompatibility of PLA and PLGA microspheres Adv. Drug Deliv. Rev. 28 1 1997 5 24
-
(1997)
Adv. Drug Deliv. Rev.
, vol.28
, Issue.1
, pp. 5-24
-
-
Anderson, J.M.1
Shive, M.S.2
-
12
-
-
0036278466
-
Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes
-
G. De Rosa, F. Quaglia, M.I. La Rotonda, M. Appel, H. Alphandary, and E. Fattal Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes J. Pharm. Sci. 91 3 2002 790 799
-
(2002)
J. Pharm. Sci.
, vol.91
, Issue.3
, pp. 790-799
-
-
De Rosa, G.1
Quaglia, F.2
La Rotonda, M.I.3
Appel, M.4
Alphandary, H.5
Fattal, E.6
-
13
-
-
0037453175
-
A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes
-
G. De Rosa, A. Bochot, F. Quaglia, M. Besnard, and E. Fattal A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes Int. J. Pharm. 254 1 2003 89 93
-
(2003)
Int. J. Pharm.
, vol.254
, Issue.1
, pp. 89-93
-
-
De Rosa, G.1
Bochot, A.2
Quaglia, F.3
Besnard, M.4
Fattal, E.5
-
14
-
-
0037503753
-
Long-term release and improved intracellular penetration of oligonucleotide-polyethylenimine complexes entrapped in biodegradable microspheres
-
G. De Rosa, F. Quaglia, A. Bochot, F. Ungaro, and E. Fattal Long-term release and improved intracellular penetration of oligonucleotide- polyethylenimine complexes entrapped in biodegradable microspheres Biomacromolecules 4 3 2003 529 536
-
(2003)
Biomacromolecules
, vol.4
, Issue.3
, pp. 529-536
-
-
De Rosa, G.1
Quaglia, F.2
Bochot, A.3
Ungaro, F.4
Fattal, E.5
-
15
-
-
21044440000
-
Enhanced intracellular uptake and inhibition of NF-kappaB activation by decoy oligonucleotide released from PLGA microspheres
-
G. De Rosa, M.C. Maiuri, F. Ungaro, D. De Stefano, F. Quaglia, M.I. La Rotonda, and R. Carnuccio Enhanced intracellular uptake and inhibition of NF-kappaB activation by decoy oligonucleotide released from PLGA microspheres J. Gene. Med. 7 6 2005 771 781
-
(2005)
J. Gene. Med.
, vol.7
, Issue.6
, pp. 771-781
-
-
De Rosa, G.1
Maiuri, M.C.2
Ungaro, F.3
De Stefano, D.4
Quaglia, F.5
La Rotonda, M.I.6
Carnuccio, R.7
-
16
-
-
39649104546
-
Ant-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice
-
N. Murata, Y. Takashima, K. Toyoshima, M. Yamamoto, and H. Okada Ant-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice J. Controlled Release 126 2008 246 254
-
(2008)
J. Controlled Release
, vol.126
, pp. 246-254
-
-
Murata, N.1
Takashima, Y.2
Toyoshima, K.3
Yamamoto, M.4
Okada, H.5
-
17
-
-
0036182057
-
Size-dependency of dl-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium
-
E. Horisawa, K. Kubota, I. Tuboi, K. Sato, H. Yamamoto, H. Takeuchi, and Y. Kawashima Size-dependency of dl-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium Pharm. Res. 19 2 2002 132 139
-
(2002)
Pharm. Res.
, vol.19
, Issue.2
, pp. 132-139
-
-
Horisawa, E.1
Kubota, K.2
Tuboi, I.3
Sato, K.4
Yamamoto, H.5
Takeuchi, H.6
Kawashima, Y.7
-
18
-
-
0347264779
-
Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: Application to interleukin 10 therapy in experimental arthritis
-
N. Perez, P. Plence, V. Millet, D. Greuet, C. Minot, D. Noel, O. Danos, C. Jorgensen, and F. Apparailly Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis Hum. Gene. Ther. 13 18 2002 2161 2172
-
(2002)
Hum. Gene. Ther.
, vol.13
, Issue.18
, pp. 2161-2172
-
-
Perez, N.1
Plence, P.2
Millet, V.3
Greuet, D.4
Minot, C.5
Noel, D.6
Danos, O.7
Jorgensen, C.8
Apparailly, F.9
-
19
-
-
33748504567
-
Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b+ regulatory T cells
-
L.M. Charbonnier, L.M. van Duivenvoorde, F. Apparailly, C. Cantos, W.G. Han, D. Noël, C. Duperray, T.W. Huizinga, R.E. Toes, C. Jorgensen, and P. Louis-Plence Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b+ regulatory T cells J. Immunol. 177 6 2006 3806 3813
-
(2006)
J. Immunol.
, vol.177
, Issue.6
, pp. 3806-3813
-
-
Charbonnier, L.M.1
Van Duivenvoorde, L.M.2
Apparailly, F.3
Cantos, C.4
Han, W.G.5
Noël, D.6
Duperray, C.7
Huizinga, T.W.8
Toes, R.E.9
Jorgensen, C.10
Louis-Plence, P.11
-
20
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
W. Strober, I. Fuss, and P. Mannon The fundamental basis of inflammatory bowel disease J. Clin. Invest. 117 3 2007 514 521
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.3
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
21
-
-
34249929951
-
Biological therapies in inflammatory bowel disease: Top-down or bottom-up?
-
B. Oldenburg, and D. Hommes Biological therapies in inflammatory bowel disease: top-down or bottom-up? Curr. Opin. Gastroenterol. 23 4 2007 395 399
-
(2007)
Curr. Opin. Gastroenterol.
, vol.23
, Issue.4
, pp. 395-399
-
-
Oldenburg, B.1
Hommes, D.2
-
22
-
-
0033125226
-
Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
-
W.J. Sandborn, and S.B. Hanauer Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety Inflamm. Bowel. Dis. 5 2 1999 119 133
-
(1999)
Inflamm. Bowel. Dis.
, vol.5
, Issue.2
, pp. 119-133
-
-
Sandborn, W.J.1
Hanauer, S.B.2
-
23
-
-
0037630207
-
New biological therapies in inflammatory bowel disease
-
S.J. van Deventer New biological therapies in inflammatory bowel disease Best Pract Res. Clin. Gastroenterol. 17 1 2003 119 130
-
(2003)
Best Pract Res. Clin. Gastroenterol.
, vol.17
, Issue.1
, pp. 119-130
-
-
Van Deventer, S.J.1
-
24
-
-
70149099162
-
Biological therapies for inflammatory bowel disease: Controversies and future options
-
A. Papa, G. Mocci, M. Bonizzi, C. Felice, G. Andrisani, G. Papa, and A. Gasbarrini Biological therapies for inflammatory bowel disease: controversies and future options Expert Rev. Clin. Pharmacol. 2 4 2009 391 403
-
(2009)
Expert Rev. Clin. Pharmacol.
, vol.2
, Issue.4
, pp. 391-403
-
-
Papa, A.1
Mocci, G.2
Bonizzi, M.3
Felice, C.4
Andrisani, G.5
Papa, G.6
Gasbarrini, A.7
-
25
-
-
67651154470
-
Safety of anti-tumor necrosis factor therapy in inflammatory bowel disease
-
F. Hoentjen, and A.A. van Bodegraven Safety of anti-tumor necrosis factor therapy in inflammatory bowel disease World J. Gastroenterol. 15 17 2009 2067 2073
-
(2009)
World J. Gastroenterol.
, vol.15
, Issue.17
, pp. 2067-2073
-
-
Hoentjen, F.1
Van Bodegraven, A.A.2
-
26
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
D.R. Sorensen, M. Leirdal, and M. Sioud Gene silencing by systemic delivery of synthetic siRNAs in adult mice J. Mol. Biol. 327 4 2003 761 766
-
(2003)
J. Mol. Biol.
, vol.327
, Issue.4
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
27
-
-
73349104443
-
Tumor necrosis factor alpha-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis
-
A. Inoue, I. Matsumoto, Y. Tanaka, K. Iwanami, A. Kanamori, N. Ochiai, D. Goto, S. Ito, and T. Sumida Tumor necrosis factor alpha-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis Arthritis Res. Ther. 11 4 2009 R118
-
(2009)
Arthritis Res. Ther.
, vol.11
, Issue.4
, pp. 118
-
-
Inoue, A.1
Matsumoto, I.2
Tanaka, Y.3
Iwanami, K.4
Kanamori, A.5
Ochiai, N.6
Goto, D.7
Ito, S.8
Sumida, T.9
-
28
-
-
69549097534
-
Nano and microtechnologies for the delivery of oligonucleotides with gene silencing properties
-
G. De Rosa, and M.I. La Rotonda Nano and microtechnologies for the delivery of oligonucleotides with gene silencing properties Molecules 14 8 2009 2801 2823
-
(2009)
Molecules
, vol.14
, Issue.8
, pp. 2801-2823
-
-
De Rosa, G.1
La Rotonda, M.I.2
-
29
-
-
49549101615
-
Efficient suppression of murine arthritis by combined anticytokine small interfering RNA lipoplexes
-
M. Khoury, V. Escriou, G. Courties, A. Galy, R. Yao, C. Largeau, D. Scherman, C. Jorgensen, and F. Apparailly Efficient suppression of murine arthritis by combined anticytokine small interfering RNA lipoplexes Arthritis Rheum. 58 8 2008 2356 2367
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.8
, pp. 2356-2367
-
-
Khoury, M.1
Escriou, V.2
Courties, G.3
Galy, A.4
Yao, R.5
Largeau, C.6
Scherman, D.7
Jorgensen, C.8
Apparailly, F.9
-
30
-
-
0036108432
-
Prolonged anti-inflammatory action of dl-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit
-
E. Horisawa, T. Hirota, S. Kawazoe, J. Yamada, H. Yamamoto, H. Takeuchi, and Y. Kawashima Prolonged anti-inflammatory action of dl-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit Pharm. Res. 19 2002 403 410
-
(2002)
Pharm. Res.
, vol.19
, pp. 403-410
-
-
Horisawa, E.1
Hirota, T.2
Kawazoe, S.3
Yamada, J.4
Yamamoto, H.5
Takeuchi, H.6
Kawashima, Y.7
-
32
-
-
84870489351
-
Polymeric nano and microparticles for the delivery of antisense oligonucleotides and SiRNA
-
Nancy Smyth Templeton 3rd ed. Taylor & Francis Group, CRC Press
-
E. Fattal, and G. De Rosa Polymeric nano and microparticles for the delivery of antisense oligonucleotides and SiRNA Nancy Smyth Templeton Gene and Cell Therapy: Therapeutic Mechanisms and Strategies 3rd ed. 2008 Taylor & Francis Group, CRC Press 599 615
-
(2008)
Gene and Cell Therapy: Therapeutic Mechanisms and Strategies
, pp. 599-615
-
-
Fattal, E.1
De Rosa, G.2
-
33
-
-
55649089421
-
State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers
-
E. Fattal, and A. Bochot State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers Int. J. Pharm. 364 2 2008 237 248
-
(2008)
Int. J. Pharm.
, vol.364
, Issue.2
, pp. 237-248
-
-
Fattal, E.1
Bochot, A.2
-
34
-
-
78650697312
-
High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: Quality by design optimization and characterization
-
D. Cun, D.K. Jensen, M.J. Maltesen, M. Bunker, P. Whiteside, D. Scurr, C. Foged, and H.M. Nielsen High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization Eur. J. Pharm. Biopharm. 77 1 2011 26 35
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.77
, Issue.1
, pp. 26-35
-
-
Cun, D.1
Jensen, D.K.2
Maltesen, M.J.3
Bunker, M.4
Whiteside, P.5
Scurr, D.6
Foged, C.7
Nielsen, H.M.8
-
35
-
-
79959915001
-
Controlled release of anti-inflammatory siRNA from biodegradable polymeric microparticles intended for intra-articular delivery to the temporomandibular joint
-
P.M. Mountziaris, D.C. Sing, S.A. Chew, S.N. Tzouanas, E.D. Lehman, F.K. Kasper, and A.G. Mikos Controlled release of anti-inflammatory siRNA from biodegradable polymeric microparticles intended for intra-articular delivery to the temporomandibular joint Pharm. Res. 28 6 2011 1370 1384
-
(2011)
Pharm. Res.
, vol.28
, Issue.6
, pp. 1370-1384
-
-
Mountziaris, P.M.1
Sing, D.C.2
Chew, S.A.3
Tzouanas, S.N.4
Lehman, E.D.5
Kasper, F.K.6
Mikos, A.G.7
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