-
1
-
-
85047688069
-
Inflammatory bowel disease: Progress and current concepts of etiopathogenesis
-
Scaldaferri F, Fiocchi C. Inflammatory bowel disease: progress and current concepts of etiopathogenesis. J. Dig. Dis. 4, 171-178 (2007).
-
(2007)
J. Dig. Dis
, vol.4
, pp. 171-178
-
-
Scaldaferri, F.1
Fiocchi, C.2
-
2
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314, 1461-1463 (2006).
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
3
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427-434 (2007).
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
4
-
-
34047178588
-
Cytochine therapy for Crohn's disease: Advances in translational research
-
Pizarro TT, Cominelli F. Cytochine therapy for Crohn's disease: advances in translational research. Annu. Rev. Med. 58, 433-444 (2007).
-
(2007)
Annu. Rev. Med
, vol.58
, pp. 433-444
-
-
Pizarro, T.T.1
Cominelli, F.2
-
5
-
-
34547734621
-
Phenotipic and functional features of human Th 17 cells
-
Annunziato F, Cosmi L, Santarlasci V et al. Phenotipic and functional features of human Th 17 cells. J. Exp. Med. 204, 1849-1861 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
-
6
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
Fujino S, Andoh A, Bamba S et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52(1), 65-70 (2003).
-
(2003)
Gut
, vol.52
, Issue.1
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
-
7
-
-
43549099743
-
The interleukin-23/interleukin-17 axis in intestinal inflammation
-
Maloy KJ. The interleukin-23/interleukin-17 axis in intestinal inflammation. J. Intern. Med. 263, 584-590 (2008).
-
(2008)
J. Intern. Med
, vol.263
, pp. 584-590
-
-
Maloy, K.J.1
-
8
-
-
0034005581
-
Role of cytochines in the pathogenesis of inflammatory bowel disease
-
Papadakis KA, Targan SR. Role of cytochines in the pathogenesis of inflammatory bowel disease. Ann. Rev. Med. 51, 289-298 (2000).
-
(2000)
Ann. Rev. Med
, vol.51
, pp. 289-298
-
-
Papadakis, K.A.1
Targan, S.R.2
-
9
-
-
0030209985
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease: Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease: Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 157, 1261-1270 (1996).
-
(1996)
J. Immunol
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
-
10
-
-
0025912981
-
Serum concentrations of tumour necrosis factor α in childhood chronic inflammatory bowel disease
-
Murch SH, Lamkin VA, Savage MO et al. Serum concentrations of tumour necrosis factor α in childhood chronic inflammatory bowel disease. Gut 32, 913-917 (1991).
-
(1991)
Gut
, vol.32
, pp. 913-917
-
-
Murch, S.H.1
Lamkin, V.A.2
Savage, M.O.3
-
11
-
-
0027486125
-
Location of tumour necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease
-
Murch SH, Braegger CP, Walker-Smith JA et al. Location of tumour necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease. Gut 34, 1705-1709 (1993).
-
(1993)
Gut
, vol.34
, pp. 1705-1709
-
-
Murch, S.H.1
Braegger, C.P.2
Walker-Smith, J.A.3
-
12
-
-
0026531017
-
Tumour necrosis factor α in stool as a marker of intestinal inflammation
-
Braegger CP, Nicholls S, Murch SH et al. Tumour necrosis factor α in stool as a marker of intestinal inflammation. Lancet 339, 89-91 (1992).
-
(1992)
Lancet
, vol.339
, pp. 89-91
-
-
Braegger, C.P.1
Nicholls, S.2
Murch, S.H.3
-
13
-
-
53849097306
-
Nonimmune cells in inflammatory bowel disease: From victim to villain
-
Danese S. Nonimmune cells in inflammatory bowel disease: from victim to villain. Trends Immunol. 29, 555-564 (2008).
-
(2008)
Trends Immunol
, vol.29
, pp. 555-564
-
-
Danese, S.1
-
14
-
-
0034186168
-
Anti-TNF therapy for Crohn's disease: A perspective (infliximab is not the drug we have been waiting for)
-
Shanahan F. Anti-TNF therapy for Crohn's disease: a perspective (infliximab is not the drug we have been waiting for). Inflamm. Bowel Dis. 6, 137-139 (2000).
-
(2000)
Inflamm. Bowel Dis
, vol.6
, pp. 137-139
-
-
Shanahan, F.1
-
15
-
-
70149093836
-
A role for TNFα and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease
-
Plevy SE, Landres CJ, Prehn J et al. A role for TNFα and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease. J. Immunol. 59, 62-76 (1997).
-
(1997)
J. Immunol
, vol.59
, pp. 62-76
-
-
Plevy, S.E.1
Landres, C.J.2
Prehn, J.3
-
16
-
-
0033778364
-
Tumor necrosis factor: Biology and therapeutic inhibitors
-
Papadakis KA, Targan SR. Tumor necrosis factor: biology and therapeutic inhibitors. Gastroenterology 119, 1148-1157 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 1148-1157
-
-
Papadakis, K.A.1
Targan, S.R.2
-
17
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, Van Deventer SJ et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group. N. Engl. J. Med. 337, 1029-1035 (1997).
-
(1997)
N. Engl. J. Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
-
18
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: The ACCENT I randomized trial
-
Hanauer SB, Feagan BG, Lichtenstein GR et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomized trial. Lancet 359, 1541-1549 (2002).
-
(2002)
Lancet
, vol.359
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
-
19
-
-
0033529049
-
Infliximab for the treatment of fistulas in patients with Crohn's disease
-
Present DH, Rutgeerts P, Targan SR et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N. Engl. J. Med. 340, 1398-1405 (1999).
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1398-1405
-
-
Present, D.H.1
Rutgeerts, P.2
Targan, S.R.3
-
20
-
-
10744221312
-
Infliximab maintenance therapy for fistulizing Crohn's disease
-
Sands BE, Blank MA, Patel K et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N. Engl. J. Med. 350, 934-936 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 934-936
-
-
Sands, B.E.1
Blank, M.A.2
Patel, K.3
-
21
-
-
0036066936
-
Infliximab improves quality of life in patients with Crohn's disease
-
Lichtenstein GR, Bala M, Han C et al. Infliximab improves quality of life in patients with Crohn's disease. Inflamm. Bowel Dis. 8, 237-243 (2002).
-
(2002)
Inflamm. Bowel Dis
, vol.8
, pp. 237-243
-
-
Lichtenstein, G.R.1
Bala, M.2
Han, C.3
-
22
-
-
33646147141
-
Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry
-
Lichtenstein GR, Feagan BG, Cohen RD et al. Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry. Clin. Gastroenterol. Hepatol. 4, 621-630 (2006).
-
(2006)
Clin. Gastroenterol. Hepatol
, vol.4
, pp. 621-630
-
-
Lichtenstein, G.R.1
Feagan, B.G.2
Cohen, R.D.3
-
23
-
-
0036188187
-
Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (infliximab) versus placebo in active spondylarthropathy
-
Van Den Bosch F, Kruithof E, Baeten D et al. Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (infliximab) versus placebo in active spondylarthropathy. Arthritis Rheum. 46, 755-765 (2002).
-
(2002)
Arthritis Rheum
, vol.46
, pp. 755-765
-
-
Van Den Bosch, F.1
Kruithof, E.2
Baeten, D.3
-
24
-
-
0037029430
-
Treatment of active ankylosing spondylitis with infliximab: A randomised controlled multicentre trial
-
Braun J, Brandt J, Listing J et al. Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial. Lancet 358, 1187-1193 (2002).
-
(2002)
Lancet
, vol.358
, pp. 1187-1193
-
-
Braun, J.1
Brandt, J.2
Listing, J.3
-
25
-
-
0037007683
-
Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α
-
Gorman JD, Sack KE, Davis JC Jr. Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α. N. Engl. J. Med. 346, 1349-1356 (2002).
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1349-1356
-
-
Gorman, J.D.1
Sack, K.E.2
Davis Jr., J.C.3
-
26
-
-
25144468057
-
Infliximab for the treatment of pyoderma gangrenosum: A randomised, double-blind placebo controlled trial
-
Abstract A-146
-
Brooklyn T, Shetty A, Bowden J et al. Infliximab for the treatment of pyoderma gangrenosum: a randomised, double-blind placebo controlled trial. Gastroenterology 128(4 Suppl. 2), A-26 (2005) (Abstract A-146).
-
(2005)
Gastroenterology
, vol.128
, Issue.4 SUPPL. 2
-
-
Brooklyn, T.1
Shetty, A.2
Bowden, J.3
-
27
-
-
0037478882
-
Infliximab in the treatment of refractory posterior uveitis
-
Joseph A, Raj D, Dua HS et al. Infliximab in the treatment of refractory posterior uveitis. Ophthalmology 110, 1449-1453 (2003).
-
(2003)
Ophthalmology
, vol.110
, pp. 1449-1453
-
-
Joseph, A.1
Raj, D.2
Dua, H.S.3
-
28
-
-
0036897465
-
Anti-tumor necrosis factor-α therapy with infliximab as an alternative to corticosteroids in the treatment of human leucocyte antigen B27-associated acute anterior uveitis
-
El-Shabrawi Y, Hermann J. Anti-tumor necrosis factor-α therapy with infliximab as an alternative to corticosteroids in the treatment of human leucocyte antigen B27-associated acute anterior uveitis. Ophthalmology 109, 2342-2346 (2002).
-
(2002)
Ophthalmology
, vol.109
, pp. 2342-2346
-
-
El-Shabrawi, Y.1
Hermann, J.2
-
29
-
-
33947397636
-
Induction and maintenance infliximab therapy for the treatment of moderate to severe Crohn's disease in children
-
Hyams J, Crandal W, Kugathasan S et al. Induction and maintenance infliximab therapy for the treatment of moderate to severe Crohn's disease in children. Gastroenterology 132, 863-873 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 863-873
-
-
Hyams, J.1
Crandal, W.2
Kugathasan, S.3
-
30
-
-
20444432816
-
A randomized placebo-controlled trial of infliximab therapy for active ulcerative colitis: Act I trial
-
Abstract 889
-
Rutgeerts P, Feagan BG, Olson A et al. A randomized placebo-controlled trial of infliximab therapy for active ulcerative colitis: act I trial. Gastroenterology 128(4 Suppl. 2), A-105 (2005) (Abstract 889).
-
(2005)
Gastroenterology
, vol.128
, Issue.4 SUPPL. 2
-
-
Rutgeerts, P.1
Feagan, B.G.2
Olson, A.3
-
31
-
-
20444487429
-
Infliximab induction and maintenance therapy for ulcerative colitis: The Act 2 trial
-
Abstract 688
-
Sandborn WJ, Rachmilewitz D, Hanauer SB et al. Infliximab induction and maintenance therapy for ulcerative colitis: the Act 2 trial. Gastroenterology 128(4 Suppl. 2), A-104 (2005) (Abstract 688).
-
(2005)
Gastroenterology
, vol.128
, Issue.4 SUPPL. 2
-
-
Sandborn, W.J.1
Rachmilewitz, D.2
Hanauer, S.B.3
-
32
-
-
36749070996
-
Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor α agents
-
Nesbitt A, Fossati G, Bergin M. et al. Mechanism of action of certolizumab pegol (CDP870): in vitro comparison with other anti-tumor necrosis factor α agents. Inflamm. Bowel Dis. 13, 1323-1332 (2007).
-
(2007)
Inflamm. Bowel Dis
, vol.13
, pp. 1323-1332
-
-
Nesbitt, A.1
Fossati, G.2
Bergin, M.3
-
33
-
-
32044451548
-
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
-
Hanauer SB, Sandborn WJ, Rutgeerts P et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 130, 323-333 (2006).
-
(2006)
Gastroenterology
, vol.130
, pp. 323-333
-
-
Hanauer, S.B.1
Sandborn, W.J.2
Rutgeerts, P.3
-
34
-
-
34249281002
-
Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
-
Sandborn WJ, Hanauer SB, Rutgeerts P et al. Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial. Gut 56, 1232-1239 (2007).
-
(2007)
Gut
, vol.56
, pp. 1232-1239
-
-
Sandborn, W.J.1
Hanauer, S.B.2
Rutgeerts, P.3
-
35
-
-
33846242958
-
Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
-
Colombel JF, Sandborn WJ, Rutgeerts P et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 132, 52-65 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 52-65
-
-
Colombel, J.F.1
Sandborn, W.J.2
Rutgeerts, P.3
-
36
-
-
44349175883
-
Sustainability of adalimumab in fistula healing and response: 2-year data from CHARM and 12 month open-label extension follow-up study
-
S
-
Colombel JF, Schwartz MK et al. Sustainability of adalimumab in fistula healing and response: 2-year data from CHARM and 12 month open-label extension follow-up study. Am. J. Gastroenterol. 102, S497 (2007).
-
(2007)
Am. J. Gastroenterol
, vol.102
, pp. 497
-
-
Colombel, J.F.1
Schwartz, M.K.2
-
37
-
-
34347402306
-
Adalimumab induction therapy for Crohn's disease previously treated with infliximab
-
Sandborn WJ, Rutgeerts P, Enns R et al. Adalimumab induction therapy for Crohn's disease previously treated with infliximab. Ann. Intern. Med. 146, 829-838 (2007).
-
(2007)
Ann. Intern. Med
, vol.146
, pp. 829-838
-
-
Sandborn, W.J.1
Rutgeerts, P.2
Enns, R.3
-
38
-
-
34447523749
-
Certolizumab pegol for the treatment of Crohn's disease
-
Sandborn WJ, Feagan BG, Stoinov S et al. Certolizumab pegol for the treatment of Crohn's disease. N. Engl. J. Med. 357, 228-238 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 228-238
-
-
Sandborn, W.J.1
Feagan, B.G.2
Stoinov, S.3
-
39
-
-
24144483087
-
A randomised, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
-
Schreiber S, Rutgeerts P, Fedorak RNN et al. A randomised, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology 129, 807-818 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 807-818
-
-
Schreiber, S.1
Rutgeerts, P.2
Fedorak, R.N.N.3
-
40
-
-
34447515607
-
Maintenance therapy with certolizumab pegol for Crohns disease
-
Schreiber S, Khaliq-Kareemi M, Lawrance IC et al. Maintenance therapy with certolizumab pegol for Crohns disease. N. Engl. J. Med. 357, 239-250 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 239-250
-
-
Schreiber, S.1
Khaliq-Kareemi, M.2
Lawrance, I.C.3
-
41
-
-
70149114774
-
Assessment of certolizumab pegol in the treatment of Crohn's disease patients for whom infliximab treatment was not successful: Open-label induction preliminary results from the WELCOME study
-
Abstract 9
-
Vermeire S, Abreu MT, D'Haens G et al. Assessment of certolizumab pegol in the treatment of Crohn's disease patients for whom infliximab treatment was not successful: open-label induction preliminary results from the WELCOME study. J. Crohn's Colitis 2, 4 (2008) (Abstract 9).
-
(2008)
J. Crohn's Colitis
, vol.2
, pp. 4
-
-
Vermeire, S.1
Abreu, M.T.2
D'Haens, G.3
-
42
-
-
33644877046
-
Early or late guided missile in the treatment of Crohn's disease?
-
Caprilli R, Angelucci E, Cocco A et al. Early or late guided missile in the treatment of Crohn's disease? Dig. Liv. Dis. 37, 973-979 (2005).
-
(2005)
Dig. Liv. Dis
, vol.37
, pp. 973-979
-
-
Caprilli, R.1
Angelucci, E.2
Cocco, A.3
-
43
-
-
33847684264
-
Clinical perspectives in Crohn's disease. Turning traditional treatment strategies on their heads: Current evidence for "step-up" versus "top-down
-
Hanauer SB. Clinical perspectives in Crohn's disease. Turning traditional treatment strategies on their heads: current evidence for "step-up" versus "top-down". Rev. Gastroenterol. Disord. 7(Suppl. 2), S17-S22 (2007).
-
(2007)
Rev. Gastroenterol. Disord
, vol.7
, Issue.SUPPL. 2
-
-
Hanauer, S.B.1
-
44
-
-
35448971037
-
Medical therapy for Crohn's disease: Top-down or step-up?
-
Baert P, Caprilli R, Angelucci E et al. Medical therapy for Crohn's disease: top-down or step-up? Dig. Dis. 25, 260-266 (2007).
-
(2007)
Dig. Dis
, vol.25
, pp. 260-266
-
-
Baert, P.1
Caprilli, R.2
Angelucci, E.3
-
45
-
-
34249929951
-
Biological therapies in inflammatory bowel disease: Top-down or bottom-up?
-
Oldenburg B, Hommes D. Biological therapies in inflammatory bowel disease: top-down or bottom-up? Curr. Opin. Gastroenterol. 23, 395-399 (2007).
-
(2007)
Curr. Opin. Gastroenterol
, vol.23
, pp. 395-399
-
-
Oldenburg, B.1
Hommes, D.2
-
46
-
-
29444445452
-
A randomized controlled trial evaluating the ideal medical management for Crohn's disease (CD): Top-down versus step-up strategies
-
Hommes D, Baert F, Van Assche G et al. A randomized controlled trial evaluating the ideal medical management for Crohn's disease (CD): top-down versus step-up strategies. Gastroenterology 128(Suppl. 2), A577 (2005).
-
(2005)
Gastroenterology
, vol.128
, Issue.SUPPL. 2
-
-
Hommes, D.1
Baert, F.2
Van Assche, G.3
-
47
-
-
39449085441
-
Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: An open randomised trial
-
D'Haens G, Baert F, Van Assche G et al. Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 371, 660-667 (2008).
-
(2008)
Lancet
, vol.371
, pp. 660-667
-
-
D'Haens, G.1
Baert, F.2
Van Assche, G.3
-
48
-
-
35948960797
-
Resource use in patients with Crohn's disease treated with infliximab
-
Saro C, Da La Coba C, Casado MA et al. Resource use in patients with Crohn's disease treated with infliximab. Aliment. Pharmacol. Ther. 26, 1313-1323 (2007).
-
(2007)
Aliment. Pharmacol. Ther
, vol.26
, pp. 1313-1323
-
-
Saro, C.1
Da La2
Coba, C.3
Casado, M.A.4
-
49
-
-
36549063053
-
Infliximab dose escalation vs. initiation of adalimumab for loss of response in Crohn's disease: A cost - effectiveness analysis
-
Kaplan GG, Hur C, Korzenik J et al. Infliximab dose escalation vs. initiation of adalimumab for loss of response in Crohn's disease: a cost - effectiveness analysis. Aliment. Pharmacol. Ther. 26, 1509-1520 (2007).
-
(2007)
Aliment. Pharmacol. Ther
, vol.26
, pp. 1509-1520
-
-
Kaplan, G.G.1
Hur, C.2
Korzenik, J.3
-
50
-
-
41149119335
-
Opportunistic infections in patients with inflammatory bowel disease: Prevention and diagnosis
-
Viget N, Vernier-Massouille G, Salmon-Ceron D et al. Opportunistic infections in patients with inflammatory bowel disease: prevention and diagnosis. Gut 57, 549-558 (2008).
-
(2008)
Gut
, vol.57
, pp. 549-558
-
-
Viget, N.1
Vernier-Massouille, G.2
Salmon-Ceron, D.3
-
51
-
-
0035846326
-
Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent
-
Keane J, Gershon S, Wise RP et al. Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent. N. Engl. J. Med. 345, 1098-1104 (2001).
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 1098-1104
-
-
Keane, J.1
Gershon, S.2
Wise, R.P.3
-
52
-
-
33747013894
-
Guidelines for treatment with infliximab for Crohn's disease
-
Hommes DW, Oldenburg B, Van Bodegraven AA et al. Guidelines for treatment with infliximab for Crohn's disease. Neth. J. Med. 64, 219-229 (2006).
-
(2006)
Neth. J. Med
, vol.64
, pp. 219-229
-
-
Hommes, D.W.1
Oldenburg, B.2
Van Bodegraven, A.A.3
-
53
-
-
1042290327
-
Tuberculosis infection in patients with rheumatoid arthritis and the effect of infliximab therapy
-
Wolfe F, Michaud K, Anderson J et al. Tuberculosis infection in patients with rheumatoid arthritis and the effect of infliximab therapy. Arth. Rheum. 50, 372-379 (2004).
-
(2004)
Arth. Rheum
, vol.50
, pp. 372-379
-
-
Wolfe, F.1
Michaud, K.2
Anderson, J.3
-
54
-
-
2342468669
-
Granulomatous infectious diseases associated with tumor necrosis factor antagonists
-
Wallis RS, Broder MS, Wong JY et al. Granulomatous infectious diseases associated with tumor necrosis factor antagonists, Clin. Infect. Dis. 38, 1261-1265 (2004).
-
(2004)
Clin. Infect. Dis
, vol.38
, pp. 1261-1265
-
-
Wallis, R.S.1
Broder, M.S.2
Wong, J.Y.3
-
55
-
-
0041653315
-
Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active-surveillance report
-
Gomez-Reino JJ, Carmona L, Valverde VR et al. Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report. Arth. Rheum. 48, 2122-2127 (2003).
-
(2003)
Arth. Rheum
, vol.48
, pp. 2122-2127
-
-
Gomez-Reino, J.J.1
Carmona, L.2
Valverde, V.R.3
-
56
-
-
0347991877
-
The safety profile of infliximab in patients with Crohn's disease: The Mayo Clinic experience in 500 patients
-
Colombel JF, Loftus EV, Tremaine WJ et al. The safety profile of infliximab in patients with Crohn's disease: the Mayo Clinic experience in 500 patients. Gastroenterology 126, 19-31 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 19-31
-
-
Colombel, J.F.1
Loftus, E.V.2
Tremaine, W.J.3
-
57
-
-
36749029427
-
Review article: Minimizing tuberculosis during anti-tumor necrosis factor-α treatment in inflammatory bowel disease
-
Theis VS, Rhodes JM. Review article: minimizing tuberculosis during anti-tumor necrosis factor-α treatment in inflammatory bowel disease. Aliment. Pharmacol. Ther. 27, 19-30 (2008).
-
(2008)
Aliment. Pharmacol. Ther
, vol.27
, pp. 19-30
-
-
Theis, V.S.1
Rhodes, J.M.2
-
58
-
-
25444517037
-
BTS recommendations for assessing risk and for managing Mycobacterium tuberculosis infection and disease in patients due to start anti-TNF α treatment
-
British Thoracic Society Standards of Care Committee
-
British Thoracic Society Standards of Care Committee. BTS recommendations for assessing risk and for managing Mycobacterium tuberculosis infection and disease in patients due to start anti-TNF α treatment. Thorax 60, 800-805 (2005).
-
(2005)
Thorax
, vol.60
, pp. 800-805
-
-
-
59
-
-
25444462780
-
Preventing TB in patients with Crohn's disease needing infliximab or other anti-TNF therapy
-
Rampton DS. Preventing TB in patients with Crohn's disease needing infliximab or other anti-TNF therapy. Gut 54, 1360-1362 (2005).
-
(2005)
Gut
, vol.54
, pp. 1360-1362
-
-
Rampton, D.S.1
-
60
-
-
33745940007
-
Diagnosis of latent tuberculosis infection: The potential role of new technologies
-
Kunst H. Diagnosis of latent tuberculosis infection: the potential role of new technologies. Respir. Med. 100, 2098-2106 (2006).
-
(2006)
Respir. Med
, vol.100
, pp. 2098-2106
-
-
Kunst, H.1
-
61
-
-
1842479974
-
High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy
-
Mow WS, Abreu-Martin MT, Papadakis KA et al. High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy. Clin. Gastroenterol. Hepatol. 2, 309-313 (2004).
-
(2004)
Clin. Gastroenterol. Hepatol
, vol.2
, pp. 309-313
-
-
Mow, W.S.1
Abreu-Martin, M.T.2
Papadakis, K.A.3
-
62
-
-
33846851795
-
-
Efthimiou P, Sood S. QuantiFERON TB Gold test: the new standard for screening of latent tuberculosis in patients with rheumatoid arthritis. Ann. Rheum. Dis. 66, 276 (2007).
-
Efthimiou P, Sood S. QuantiFERON TB Gold test: the new standard for screening of latent tuberculosis in patients with rheumatoid arthritis. Ann. Rheum. Dis. 66, 276 (2007).
-
-
-
-
63
-
-
4143087063
-
Reactivation of tuberculosis during immunosuppressive treatment in a patient with a positive QuantiFERON-RD1 test
-
Ravn P, Munk ME, Andersen AB et al. Reactivation of tuberculosis during immunosuppressive treatment in a patient with a positive QuantiFERON-RD1 test. Scand. J. Infect. Dis. 36, 499-501 (2004).
-
(2004)
Scand. J. Infect. Dis
, vol.36
, pp. 499-501
-
-
Ravn, P.1
Munk, M.E.2
Andersen, A.B.3
-
64
-
-
37749054451
-
Detection of latent tuberculosis in immunosuppressed patients with autoimmune diseases. Performance of Mycobacterium tuberculosis antigen-specific interferon γ assays
-
Matulis G, Jüni P, Villiger PM et al. Detection of latent tuberculosis in immunosuppressed patients with autoimmune diseases. Performance of Mycobacterium tuberculosis antigen-specific interferon γ assays. Ann. Rheum. Dis. 67, 84-90 (2008).
-
(2008)
Ann. Rheum. Dis
, vol.67
, pp. 84-90
-
-
Matulis, G.1
Jüni, P.2
Villiger, P.M.3
-
65
-
-
0034091974
-
Targeted tuberculin testing and treatment of latent TB infection
-
American Thoracic Society
-
American Thoracic Society. Targeted tuberculin testing and treatment of latent TB infection. Am. J. Resp. Crit. Care 161, 221-247 (2000).
-
(2000)
Am. J. Resp. Crit. Care
, vol.161
, pp. 221-247
-
-
-
66
-
-
24944529247
-
TNF-blocking agents and TB. New drugs illuminate and old topic
-
Keane J. TNF-blocking agents and TB. New drugs illuminate and old topic. Rheumatology 44, 714-720 (2005).
-
(2005)
Rheumatology
, vol.44
, pp. 714-720
-
-
Keane, J.1
-
67
-
-
0346057892
-
Infliximab therapy for rheumatic disease in patients with chronic hepatitis B or C
-
Oniankitan O, Duvoux C, Challine D et al. Infliximab therapy for rheumatic disease in patients with chronic hepatitis B or C. J. Rheumatol. 31, 107-109 (2004).
-
(2004)
J. Rheumatol
, vol.31
, pp. 107-109
-
-
Oniankitan, O.1
Duvoux, C.2
Challine, D.3
-
68
-
-
23644453655
-
Improvement of renal function and disappearance of hepatitis B virus DNA in a patient with rheumatoid arthritis and renal amyloidosis following treatment with infliximab
-
Anelli MG, Torres DD, Manno C et al. Improvement of renal function and disappearance of hepatitis B virus DNA in a patient with rheumatoid arthritis and renal amyloidosis following treatment with infliximab. Arth. Rheum. 52, 2519-2520 (2005).
-
(2005)
Arth. Rheum
, vol.52
, pp. 2519-2520
-
-
Anelli, M.G.1
Torres, D.D.2
Manno, C.3
-
69
-
-
0037532694
-
Hepatitis B reactivation in a chronic hepatitis B surface antigen carrier with rheumatoid arthritis treated with infliximab and low dose of methotrexate
-
Ostuni P, Botsios C, Punzi L et al. Hepatitis B reactivation in a chronic hepatitis B surface antigen carrier with rheumatoid arthritis treated with infliximab and low dose of methotrexate. Ann. Rheum. Dis. 62, 686-687 (2003).
-
(2003)
Ann. Rheum. Dis
, vol.62
, pp. 686-687
-
-
Ostuni, P.1
Botsios, C.2
Punzi, L.3
-
70
-
-
20244379866
-
Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy
-
Wendling D, Auge B, Bettinger D et al. Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy. Ann. Rheum. Dis. 64, 788-789 (2005).
-
(2005)
Ann. Rheum. Dis
, vol.64
, pp. 788-789
-
-
Wendling, D.1
Auge, B.2
Bettinger, D.3
-
71
-
-
0038504830
-
Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for adult onset Still's disease
-
Michel M, Duvoux C, Hezode C et al. Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for adult onset Still's disease. J. Rheumatol. 30, 1624-1625 (2003).
-
(2003)
J. Rheumatol
, vol.30
, pp. 1624-1625
-
-
Michel, M.1
Duvoux, C.2
Hezode, C.3
-
72
-
-
20044386121
-
Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B
-
Ueno Y, Tanaka S, Shimamoto M et al. Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B. Dig. Dis. Sci. 50, 163-166 (2005).
-
(2005)
Dig. Dis. Sci
, vol.50
, pp. 163-166
-
-
Ueno, Y.1
Tanaka, S.2
Shimamoto, M.3
-
73
-
-
4344614501
-
Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: Need for primary prophylaxis
-
Esteve M, Saro C, Gonzalez-Huix F et al. Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: need for primary prophylaxis. Gut 53, 1363-1365 (2004).
-
(2004)
Gut
, vol.53
, pp. 1363-1365
-
-
Esteve, M.1
Saro, C.2
Gonzalez-Huix, F.3
-
74
-
-
7044270670
-
Safety of antitumor necrosis factor (anti-TNF) therapy in patients with chronic viral infections: Hepatitis C, hepatitis B, and HIV infection
-
Calabrese LH, Zein N, Vassilopoulos D. Safety of antitumor necrosis factor (anti-TNF) therapy in patients with chronic viral infections: hepatitis C, hepatitis B, and HIV infection. Ann. Rheum. Dis. 63, 18-24 (2004).
-
(2004)
Ann. Rheum. Dis
, vol.63
, pp. 18-24
-
-
Calabrese, L.H.1
Zein, N.2
Vassilopoulos, D.3
-
76
-
-
33749587637
-
Safety of anti-TNF-α therapy in rheumatoid arthritis and spondyloarthropathies with concurrent B or C chronic hepatitis
-
Roux CH, Brocq O, Breuil V et al. Safety of anti-TNF-α therapy in rheumatoid arthritis and spondyloarthropathies with concurrent B or C chronic hepatitis. Rheumatology 45, 1294-1297 (2006).
-
(2006)
Rheumatology
, vol.45
, pp. 1294-1297
-
-
Roux, C.H.1
Brocq, O.2
Breuil, V.3
-
77
-
-
47249104803
-
Use of tumor necrosis factor-α inhibitors in patients with chronic hepatitis B infection
-
Carroll MB, Bond IB. Use of tumor necrosis factor-α inhibitors in patients with chronic hepatitis B infection. Semin. Arthritis Rheum. 38(3), 208-217 (2008).
-
(2008)
Semin. Arthritis Rheum
, vol.38
, Issue.3
, pp. 208-217
-
-
Carroll, M.B.1
Bond, I.B.2
-
78
-
-
46749137801
-
Risk of lymphoma associated with anti-TNF agents for the treatment of Crohn's disease: A mew analysis
-
Abstract A 970
-
Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with anti-TNF agents for the treatment of Crohn's disease: a mew analysis. Gastroenterology 134(Suppl. 1), A-144 (2008) (Abstract A 970).
-
(2008)
Gastroenterology
, vol.134
, Issue.SUPPL. 1
-
-
Siegel, C.A.1
Marden, S.M.2
Persing, S.M.3
-
79
-
-
56549085510
-
Hepatosplenic T cell lymphoma in inflammatory bowel disease
-
Shale M, Kanfer E, Panaccione R et al. Hepatosplenic T cell lymphoma in inflammatory bowel disease. Gut 57, 1639-1641 (2008).
-
(2008)
Gut
, vol.57
, pp. 1639-1641
-
-
Shale, M.1
Kanfer, E.2
Panaccione, R.3
-
80
-
-
0347917124
-
Demyelination during anti-tumor necrosis factor α therapy with infliximab for Crohn's disease
-
Thomas CW Jr, Weinshenker BG, Sandboure WJ et al. Demyelination during anti-tumor necrosis factor α therapy with infliximab for Crohn's disease. Inflamm. Bowel Dis. 10, 28-31 (2004).
-
(2004)
Inflamm. Bowel Dis
, vol.10
, pp. 28-31
-
-
Thomas Jr, C.W.1
Weinshenker, B.G.2
Sandboure, W.J.3
-
81
-
-
0038755661
-
Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart failure: Results of the anti-TNF Therapy Against Congestive heart failure (ATTACH) trial
-
Chung ES, Packer M, Lo KH et al. Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive heart failure (ATTACH) trial. Circulation 107, 3133-3140 (2003).
-
(2003)
Circulation
, vol.107
, pp. 3133-3140
-
-
Chung, E.S.1
Packer, M.2
Lo, K.H.3
-
82
-
-
0037195727
-
Inflammatory mediators and the failing heart: Past, present, and the foreseeable future
-
Mann DL. Inflammatory mediators and the failing heart: past, present, and the foreseeable future, Circ. Res. 91, 988-998 (2002).
-
(2002)
Circ. Res
, vol.91
, pp. 988-998
-
-
Mann, D.L.1
-
83
-
-
0037434552
-
Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
-
Baert F, Norman M, Vermeire S et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N. Engl. J. Med. 348, 601-608 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 601-608
-
-
Baert, F.1
Norman, M.2
Vermeire, S.3
-
84
-
-
10744224387
-
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease
-
Rutgeerts P, Feagan BG, Lichtenstein GR et al. Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology 126, 402-413 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 402-413
-
-
Rutgeerts, P.1
Feagan, B.G.2
Lichtenstein, G.R.3
-
85
-
-
10744221312
-
Infliximab maintenance therapy for fistulizing Crohn's disease
-
Sands BE, Anderson FH, Bernstein CN et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N. Engl. J. Med. 350, 876-885 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 876-885
-
-
Sands, B.E.1
Anderson, F.H.2
Bernstein, C.N.3
-
86
-
-
33749432435
-
Association of through serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease
-
Maser EA, Villela R, Silverberg MS et al. Association of through serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin. Gastroenterol. Hepatol. 4, 1248-1254 (2006).
-
(2006)
Clin. Gastroenterol. Hepatol
, vol.4
, pp. 1248-1254
-
-
Maser, E.A.1
Villela, R.2
Silverberg, M.S.3
-
87
-
-
0037379792
-
Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: A randomized clinical trial
-
Farrell RJ, Alsahli M, Jeen YT S et al. Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized clinical trial. Gastroenterology 124, 917-924 (2003).
-
(2003)
Gastroenterology
, vol.124
, pp. 917-924
-
-
Farrell, R.J.1
Alsahli, M.2
Jeen, Y.S.3
-
88
-
-
63849251824
-
Long-term safety of infliximab for the treatment of inflammatory bowel disease: A single-centre cohort study
-
Fidder H, Schnitzler F, Ferrante M et al. Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study. Gut 58, 501-508 (2009).
-
(2009)
Gut
, vol.58
, pp. 501-508
-
-
Fidder, H.1
Schnitzler, F.2
Ferrante, M.3
-
89
-
-
33644774565
-
Evolving knowledge and therapy of inflammatory bowel disease
-
Korzenik JR, Podolsky DK. Evolving knowledge and therapy of inflammatory bowel disease. Nat. Rev. Drug Discov. 5, 197-209 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 197-209
-
-
Korzenik, J.R.1
Podolsky, D.K.2
-
90
-
-
46149125761
-
Crohn's disease: Beyond antagonists of tumour necrosis factor
-
Peyrin-Biroulet L, Desremaux P, Sandborn WJ, Colombel JF. Crohn's disease: beyond antagonists of tumour necrosis factor. Lancet 372, 67-81 (2008)
-
(2008)
Lancet
, vol.372
, pp. 67-81
-
-
Peyrin-Biroulet, L.1
Desremaux, P.2
Sandborn, W.J.3
Colombel, J.F.4
-
91
-
-
0031943618
-
The interleukin-12/ interleukin-12 receptor system: Role in normal and pathologic immune responses
-
Gately MK, Renzeti LM, Magram J et al. The interleukin-12/ interleukin-12 receptor system: role in normal and pathologic immune responses. Annu. Rev. Immunol. 16, 495-521 (1998).
-
(1998)
Annu. Rev. Immunol
, vol.16
, pp. 495-521
-
-
Gately, M.K.1
Renzeti, L.M.2
Magram, J.3
-
92
-
-
0031937388
-
Proinflammatory and immunoregulatory functions of interleukin-12
-
Trinchieri G. Proinflammatory and immunoregulatory functions of interleukin-12. Int. Rev. Immunol. 16, 365-396 (1998).
-
(1998)
Int. Rev. Immunol
, vol.16
, pp. 365-396
-
-
Trinchieri, G.1
-
93
-
-
34848850085
-
The genetics of inflammatory bowel disease
-
Cho JH, Weaver CT. The genetics of inflammatory bowel disease. Gastroenterology 133, 1327-1339 (2007).
-
(2007)
Gastroenterology
, vol.133
, pp. 1327-1339
-
-
Cho, J.H.1
Weaver, C.T.2
-
94
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
Mannon PJ, Fuss IJ, Mayer L et al. Anti-interleukin-12 antibody for active Crohn's disease. N. Engl. J. Med. 351, 2069-2079 (2004).
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
-
95
-
-
70149090799
-
-
Sandborn WJ, Feagan BJ, Fedorak R et al. A multicenter, randomized, Phase IIa study of human monoclonal antibody to IL-12/23p40 (CNTO 1275) in patients with moderately to severely active Crohn's disease. Gastroenterology 132(Suppl. 2), A-51 (Abstract/272) (2007).
-
Sandborn WJ, Feagan BJ, Fedorak R et al. A multicenter, randomized, Phase IIa study of human monoclonal antibody to IL-12/23p40 (CNTO 1275) in patients with moderately to severely active Crohn's disease. Gastroenterology 132(Suppl. 2), A-51 (Abstract/272) (2007).
-
-
-
-
96
-
-
33751226331
-
A Phase I study: Visilizumab therapy in Crohn's disease (CD) patients refractory to infliximab treatment
-
Abstract n769
-
Hommes D, Targan S, Baumgart DC et al. A Phase I study: visilizumab therapy in Crohn's disease (CD) patients refractory to infliximab treatment. Gastroenterology 130(Suppl. 2), A-111 (Abstract n769) (2006).
-
(2006)
Gastroenterology
, vol.130
, Issue.SUPPL. 2
-
-
Hommes, D.1
Targan, S.2
Baumgart, D.C.3
-
97
-
-
70149098165
-
-
Lowder JN, Baumgart DC, Hommes DW et al. A Phase I study; visilizumab therapy in Crohn's disease (CD) patients with perianal fistula. Gut 55(Suppl.) (2006) (Abstract A127).
-
Lowder JN, Baumgart DC, Hommes DW et al. A Phase I study; visilizumab therapy in Crohn's disease (CD) patients with perianal fistula. Gut 55(Suppl.) (2006) (Abstract A127).
-
-
-
-
98
-
-
35648941736
-
A Phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody in severe steroid-refractory ulcerative colitis
-
Plevy S, Salzberg B, Van Assche G et al. A Phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody in severe steroid-refractory ulcerative colitis. Gastroenterology 133, 1414-1422 (2007).
-
(2007)
Gastroenterology
, vol.133
, pp. 1414-1422
-
-
Plevy, S.1
Salzberg, B.2
Van Assche, G.3
-
99
-
-
0029798204
-
Treatment of severe Crohn's disease with anti-CD4 monoclonal antibody
-
Canva-Delcambre V, Jacquot S et al. Treatment of severe Crohn's disease with anti-CD4 monoclonal antibody. Aliment. Pharmacol. Ther. 10, 721-727 (1996).
-
(1996)
Aliment. Pharmacol. Ther
, vol.10
, pp. 721-727
-
-
Canva-Delcambre, V.1
Jacquot, S.2
-
100
-
-
0030989417
-
CD4 antibody treatment in patients with active Crohn's disease: A Phase I dose finding study
-
Stronkhorst A, Radema S, Yong SL et al. CD4 antibody treatment in patients with active Crohn's disease: a Phase I dose finding study. Gut 40, 320-327 (1997).
-
(1997)
Gut
, vol.40
, pp. 320-327
-
-
Stronkhorst, A.1
Radema, S.2
Yong, S.L.3
-
101
-
-
33750343050
-
Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: A randomised, double blind, placebo controlled, dose ranging trial
-
Van Assche G, Sandborn WJ, Feagan BG et al. Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial. Gut 55, 1568-1574 (2006).
-
(2006)
Gut
, vol.55
, pp. 1568-1574
-
-
Van Assche, G.1
Sandborn, W.J.2
Feagan, B.G.3
-
102
-
-
10744232542
-
Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis
-
Creed TJ, Norman MR, Probert CS et al. Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis. Aliment. Pharmacol. Ther. 18, 65-75 (2003).
-
(2003)
Aliment. Pharmacol. Ther
, vol.18
, pp. 65-75
-
-
Creed, T.J.1
Norman, M.R.2
Probert, C.S.3
-
103
-
-
33646232018
-
Basiliximab for the treatment of steroid-resistant ulcerative colitis: Further experience in moderate and severe disease
-
Creed TJ, Probert CS, Norman MR et al. Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe disease. Aliment. Pharmacol. Ther. 23, 1435-1442 (2006).
-
(2006)
Aliment. Pharmacol. Ther
, vol.23
, pp. 1435-1442
-
-
Creed, T.J.1
Probert, C.S.2
Norman, M.R.3
-
104
-
-
11144358366
-
A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease
-
discussion 947
-
Ito H, Takazoe M, Fukuda Y et al. A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 126, 989-996; discussion 947 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 989-996
-
-
Ito, H.1
Takazoe, M.2
Fukuda, Y.3
-
105
-
-
33746176176
-
Fontolizumab, a humanized anti-interferon γ antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
-
Hommes DW, Mikhajlowa TL, Stoinov S et al. Fontolizumab, a humanized anti-interferon γ antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease. Gut 55, 1131-1137 (2006).
-
(2006)
Gut
, vol.55
, pp. 1131-1137
-
-
Hommes, D.W.1
Mikhajlowa, T.L.2
Stoinov, S.3
-
106
-
-
33746132472
-
A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanized anti-interferon γ antibody, in patients with moderate to severe Crohn's disease
-
Reinisch W, Hommes DW, Van Assche G et al. A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanized anti-interferon γ antibody, in patients with moderate to severe Crohn's disease. Gut 55, 1138-1144 (2006).
-
(2006)
Gut
, vol.55
, pp. 1138-1144
-
-
Reinisch, W.1
Hommes, D.W.2
Van Assche, G.3
-
107
-
-
18144371659
-
Fontolizumab protein design labs
-
Dumont FJ. Fontolizumab protein design labs. Curr. Opin. Investig. Drugs 6, 537-544 (2005).
-
(2005)
Curr. Opin. Investig. Drugs
, vol.6
, pp. 537-544
-
-
Dumont, F.J.1
-
108
-
-
0026770377
-
Integrins: Versatility, modulation, and signalling in cell adhesion
-
Hynes RO. Integrins: versatility, modulation, and signalling in cell adhesion. Cell 69, 11-25 (1992).
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
109
-
-
0027407109
-
Endothelial-leukocyte adhesion molecules
-
Bevilacqua MP. Endothelial-leukocyte adhesion molecules. Ann. Rev. Immunol. 11, 767-804 (1993).
-
(1993)
Ann. Rev. Immunol
, vol.11
, pp. 767-804
-
-
Bevilacqua, M.P.1
-
110
-
-
0142157983
-
Efficacy and safety of a humanized α4β7 antibody in active Crohn's disease (CD)
-
Feagan BG, Greenberg G, Wild G et al. Efficacy and safety of a humanized α4β7 antibody in active Crohn's disease (CD). Gastroenterology 124, A25-A26 (2003).
-
(2003)
Gastroenterology
, vol.124
-
-
Feagan, B.G.1
Greenberg, G.2
Wild, G.3
-
111
-
-
33846804162
-
A randomized, double-masked, placebo-controlled study of molecule 1, for the treatment of subjects with active Crohn's disease
-
Yacyshyn BR, Chey WY, Wedel MK et al. A randomized, double-masked, placebo-controlled study of molecule 1, for the treatment of subjects with active Crohn's disease. Clin. Gastroenterol. Hepatol. 5, 215-220 (2007).
-
(2007)
Clin. Gastroenterol. Hepatol
, vol.5
, pp. 215-220
-
-
Yacyshyn, B.R.1
Chey, W.Y.2
Wedel, M.K.3
-
112
-
-
46149117709
-
PROTECT-1, prospective randomized oral therapy evaluation of CCX282-B (TRAFICET-EN) in Crohn's disease
-
Bekker P, Schreiber S, Keshav S et al. PROTECT-1, prospective randomized oral therapy evaluation of CCX282-B (TRAFICET-EN) in Crohn's disease. Gut 56(Suppl.), A23 (2007).
-
(2007)
Gut
, vol.56
, Issue.SUPPL.
-
-
Bekker, P.1
Schreiber, S.2
Keshav, S.3
-
113
-
-
0041334132
-
Therapeutic value of α-4-integrin blockade in inflammatory bowel disease: The role of natalizumab
-
Ghosh S. Therapeutic value of α-4-integrin blockade in inflammatory bowel disease: the role of natalizumab. Expert Opin. Biol. Ther. 3, 995-1000 (2003).
-
(2003)
Expert Opin. Biol. Ther
, vol.3
, pp. 995-1000
-
-
Ghosh, S.1
-
114
-
-
22844445230
-
Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
-
Langer-Gould A, Atlas SW, Green AJ et al. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N. Engl. J. Med. 353, 375-381 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 375-381
-
-
Langer-Gould, A.1
Atlas, S.W.2
Green, A.J.3
-
115
-
-
27644441529
-
Natalizumab induction and maintenance therapy for Crohn's disease
-
Sandborn WJ, Colombel JF, Enns R et al. Natalizumab induction and maintenance therapy for Crohn's disease. N. Engl. J. Med. 353, 1912-1925 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 1912-1925
-
-
Sandborn, W.J.1
Colombel, J.F.2
Enns, R.3
-
116
-
-
34247884424
-
Natalizumab for the treatment of active Crohn's disease: Results of the ENCORE trial
-
Targan SR, Feagan BG, Fedorak RN et al. Natalizumab for the treatment of active Crohn's disease: results of the ENCORE trial. Gastroenterology 132, 1672-1683 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 1672-1683
-
-
Targan, S.R.1
Feagan, B.G.2
Fedorak, R.N.3
-
117
-
-
33845999959
-
Natalizumab for induction of remission in Crohn's disease
-
Rev. CD006097
-
MacDonald JK, McDonald JW. Natalizumab for induction of remission in Crohn's disease. Cochrane Database Syst. Rev. CD006097 (2007).
-
(2007)
Cochrane Database Syst
-
-
MacDonald, J.K.1
McDonald, J.W.2
-
118
-
-
22844445587
-
Progressive multifocal leukoencephalopathy after natalizumab therapy for Chron's disease
-
Van Assche G, Van Ranst M, Sciot R et al. Progressive multifocal leukoencephalopathy after natalizumab therapy for Chron's disease. N. Engl. J. Med. 353, 362-368 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 362-368
-
-
Van Assche, G.1
Van Ranst, M.2
Sciot, R.3
-
119
-
-
22844439662
-
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon β-1a for multiple sclerosis
-
Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon β-1a for multiple sclerosis. N. Engl. J. Med. 353, 369-374 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 369-374
-
-
Kleinschmidt-DeMasters, B.K.1
Tyler, K.L.2
-
120
-
-
33745923468
-
A safety evaluation for progressive multifocal leukoencephalopathy (PML) in greater than 3500 patients with Crohn's disease (CD), multiple sclerosis (MS), and rheumatoid arthritis (RA) previously treated with natalizumab in clinical trials
-
Sandborn WJ, Targan S. A safety evaluation for progressive multifocal leukoencephalopathy (PML) in greater than 3500 patients with Crohn's disease (CD), multiple sclerosis (MS), and rheumatoid arthritis (RA) previously treated with natalizumab in clinical trials. Gastroenterology A492 (2006).
-
(2006)
Gastroenterology
, vol.A492
-
-
Sandborn, W.J.1
Targan, S.2
-
121
-
-
33644605483
-
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
-
Yousry TA, Major EO, Ryschkewitsch C et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N. Engl. J. Med. 354, 924-933 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 924-933
-
-
Yousry, T.A.1
Major, E.O.2
Ryschkewitsch, C.3
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