-
1
-
-
0030738644
-
Blood pressure response to chronic episodic hypoxia: Role of the sympathetic nervous system
-
Bao G, Metreveli N, Li R, Taylor A, Fletcher EC (1997) Blood pressure response to chronic episodic hypoxia: Role of the sympathetic nervous system. J Appl Physiol 83:95-101
-
(1997)
J Appl Physiol
, vol.83
, pp. 95-101
-
-
Bao, G.1
Metreveli, N.2
Li, R.3
Taylor, A.4
Fletcher, E.C.5
-
2
-
-
37349115260
-
Effects of aging and HIF-1 activity on angiogenic cell mobilization and recovery of perfusion following limb ischemia
-
Bosch-Marcé M, Okuyama H, Wesley JB, Sarkar K, Kimura H, Liu YV, Zhang H, Strazza M, Rey S, Savino L, Zhou YF, McDonald KR, Na Y, Vandiver S, Rabi A, Shaked Y, Kerbel R, LaVallee T, Semenza GL (2007) Effects of aging and HIF-1 activity on angiogenic cell mobilization and recovery of perfusion following limb ischemia. Circ Res 101:1310-1318
-
(2007)
Circ Res
, vol.101
, pp. 1310-1318
-
-
Bosch-Marcé, M.1
Okuyama, H.2
Wesley, J.B.3
Sarkar, K.4
Kimura, H.5
Liu, Y.V.6
Zhang, H.7
Strazza, M.8
Rey, S.9
Savino, L.10
Zhou, Y.F.11
McDonald, K.R.12
Na, Y.13
Vandiver, S.14
Rabi, A.15
Shaked, Y.16
Kerbel, R.17
LaVallee, T.18
Semenza, G.L.19
-
3
-
-
0038163900
-
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
-
Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, Semenza GL (2003) Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108:79-85
-
(2003)
Circulation
, vol.108
, pp. 79-85
-
-
Cai, Z.1
Manalo, D.J.2
Wei, G.3
Rodriguez, E.R.4
Fox-Talbot, K.5
Lu, H.6
Zweier, J.L.7
Semenza, G.L.8
-
4
-
-
38849182762
-
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial de fi ciency of HIF-1〈.
-
Cai Z, Zhong H, Bosch-Marce M, Fox-Talbot K, Wang L, Wei C, Trush MA, Semenza GL (2008) Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial de fi ciency of HIF-1〈. Cardiovasc Res 77:463-470
-
(2008)
Cardiovasc Res
, vol.77
, pp. 463-470
-
-
Cai, Z.1
Zhong, H.2
Bosch-Marce, M.3
Fox-Talbot, K.4
Wang, L.5
Wei, C.6
Trush, M.A.7
Semenza, G.L.8
-
5
-
-
33846235510
-
Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat
-
Dick TE, Hsieh YH, Wang N, Prabhakar NR (2007) Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat. Exp Physiol 92:87-97
-
(2007)
Exp Physiol
, vol.92
, pp. 87-97
-
-
Dick, T.E.1
Hsieh, Y.H.2
Wang, N.3
Prabhakar, N.R.4
-
6
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 a regulates the VEGF expression and is potentially involved in lung and vascular development
-
Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y (1997) A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1 a regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A 94:4273-4278
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii-Kuriyama, Y.6
-
7
-
-
77957372870
-
HIF-1 mediates pathogenic in fl ammatory responses to intestinal ischemia reperfusion injury
-
Feinman R, Deitch EA, Watkins AC, Abungu B, Colorado I, Kannan KB, Sheth S, Caputo FJ, Lu Q, Ramanathan M, Attan S, Badami CJ, Doucet D, Barlos D, Bosch-Marcé M, Semenza GL, Xu DZ (2010) HIF-1 mediates pathogenic in fl ammatory responses to intestinal ischemia reperfusion injury. Am J Physiol Gastrointest Liver Physiol G833-G843
-
(2010)
Am J Physiol Gastrointest Liver Physiol
-
-
Feinman, R.1
Deitch, E.A.2
Watkins, A.C.3
Abungu, B.4
Colorado, I.5
Kannan, K.B.6
Sheth, S.7
Caputo, F.J.8
Lu, Q.9
Ramanathan, M.10
Attan, S.11
Badami, C.J.12
Doucet, D.13
Barlos, D.14
Bosch-Marcé, M.15
Semenza, G.L.16
Xu, D.Z.17
-
8
-
-
0343683375
-
HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 a and developmentally expressed in blood vessels
-
Flamme I, Fröhlich T, von Reutern M, Kappel A, Damert A, Risau W 1997) HRF, a putative basic helix-loop-helix- PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 a and developmentally expressed in blood vessels. Mech Dev 63:51-60
-
(1997)
Mech Dev
, vol.63
, pp. 51-60
-
-
Flamme, I.1
Fröhlich, T.2
Von Reutern, M.3
Kappel, A.4
Damert, A.5
Risau, W.6
-
9
-
-
0026602427
-
Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats
-
Fletcher EC, Lesske J, Qian W, Miller CC 3rd, Unger T (1992) Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats. Hypertension 19:555-561
-
(1992)
Hypertension
, vol.19
, pp. 555-561
-
-
Fletcher, E.C.1
Lesske, J.2
Qian, W.3
Miller III, C.C.4
Unger, T.5
-
10
-
-
0030887045
-
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
-
Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu YZ, Pray-Grant M, Perdew GH, Brad fi eld CA (1997 Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J Biol Chem 272:8581-8593
-
(1997)
J Biol Chem
, vol.272
, pp. 8581-8593
-
-
Hogenesch, J.B.1
Chan, W.K.2
Jackiw, V.H.3
Brown, R.C.4
Gu, Y.Z.5
Pray-Grant, M.6
Perdew, G.H.7
Bradfield, C.A.8
-
11
-
-
15444342958
-
Cellular and developmental control of O 2 homeostasis by hypoxia-inducible factor 1a
-
Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL (1998) Cellular and developmental control of O 2 homeostasis by hypoxia-inducible factor 1 a . Genes Dev 12:149-162
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
12
-
-
0030787469
-
Transactivation and inhibitory domains of hypoxiainducible factor 1 a Modulation of transcriptional activity by oxygen tension
-
Jiang BH, Zheng JZ, Leung SW, Roe R, Semenza GL (1997) Transactivation and inhibitory domains of hypoxiainducible factor 1 a . Modulation of transcriptional activity by oxygen tension. J Biol Chem 272:19253-19260
-
(1997)
J Biol Chem
, vol.272
, pp. 19253-19260
-
-
Jiang, B.H.1
Zheng, J.Z.2
Leung, S.W.3
Roe, R.4
Semenza, G.L.5
-
13
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
Kaelin WG Jr, Ratcliffe PJ (2008) Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway. Mol Cell 30:393-402
-
(2008)
Mol Cell
, vol.30
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
14
-
-
79955562849
-
Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury
-
Kannan KB, Colorado I, Reino D, Palange D, Lu Q, Qin X, Watkins A, Caputo FJ, Semenza GL, Deitch EA, Feinman R (2011) Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury. Am J Physiol Gastrointest Liver Physiol 300:G853-G861
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
-
-
Kannan, K.B.1
Colorado, I.2
Reino, D.3
Palange, D.4
Lu, Q.5
Qin, X.6
Watkins, A.7
Caputo, F.J.8
Semenza, G.L.9
Deitch, E.A.10
Feinman, R.11
-
15
-
-
79953225541
-
Nitric oxide prevents axonal degeneration by inducing HIF-1-dependent expression of erythropoietin
-
Fischer
-
Keswani SC, Bosch-Marcé M, Reed N, Fischer A, Semenza GL, Hoke A (2011) Nitric oxide prevents axonal degeneration by inducing HIF-1-dependent expression of erythropoietin. Proc Natl Acad Sci U S A 108:4986-4990
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4986-4990
-
-
Keswani, S.C.1
Bosch-Marcé, M.2
Reed, N.3
Fischer, A.4
Semenza, G.L.5
Hoke, A.6
-
16
-
-
79251546780
-
NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats
-
Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR (2011) NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats. Antioxid Redox Signal 14:533-542
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 533-542
-
-
Khan, S.A.1
Nanduri, J.2
Yuan, G.3
Kinsman, B.4
Kumar, G.K.5
Joseph, J.6
Kalyanaraman, B.7
Prabhakar, N.R.8
-
17
-
-
0037154262
-
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially de fi cient for hypoxia-inducible factor 1a
-
Kline DD, Peng Y, Manalo DJ, Semenza GL, Prabhakar NR (2002) Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially de fi cient for hypoxia-inducible factor 1 a . Proc Natl Acad Sci U S A 99:821-826
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 821-826
-
-
Kline, D.D.1
Peng, Y.2
Manalo, D.J.3
Semenza, G.L.4
Prabhakar, N.R.5
-
18
-
-
33746847626
-
Chronic intermittent hypoxia induces hypoxia-evoked catecholamine ef fl ux in adult rat adrenal medulla via oxidative stress
-
Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR (2006) Chronic intermittent hypoxia induces hypoxia-evoked catecholamine ef fl ux in adult rat adrenal medulla via oxidative stress. J Physiol 229-239
-
(2006)
J Physiol
, pp. 229-239
-
-
Kumar, G.K.1
Rai, V.2
Sharma, S.D.3
Ramakrishnan, D.P.4
Peng, Y.J.5
Souvannakitti, D.6
Prabhakar, N.R.7
-
19
-
-
0031457720
-
Hypertension caused by hronic intermittent hypoxia-Influence of chemoreceptors and sympathetic nervous system
-
Lesske J, Fletcher EC, Bao G, Unger T (1997) Hypertension caused by hronic intermittent hypoxia-Influence of chemoreceptors and sympathetic nervous system. J Hypertens 12:1593-1603
-
(1997)
J Hypertens
, vol.12
, pp. 1593-1603
-
-
Lesske, J.1
Fletcher, E.C.2
Bao, G.3
Unger, T.4
-
20
-
-
33646775277
-
Altered metabolic responses to intermittent hypoxia in mice with partial de fi ciency of hypoxia-inducible factor 1 a .
-
Li J, Bosch-Marcé M, Nanayakkara A, Savransky V, Fried SK, Semenza GL, Polotsky VY (2006) Altered metabolic responses to intermittent hypoxia in mice with partial de fi ciency of hypoxia-inducible factor 1 a . Physiol Genomics 25:450-457
-
(2006)
Physiol Genomics
, vol.25
, pp. 450-457
-
-
Li, J.1
Bosch-Marcé, M.2
Nanayakkara, A.3
Savransky, V.4
Fried, S.K.5
Semenza, G.L.6
Polotsky, V.Y.7
-
21
-
-
78650887484
-
The hypoxiainducible transcription factor pathway regulates oxygen sensing in the simplest animal trichoplax adhaerens
-
Loenarz C, Coleman ML, Boleininger A, Schierwater B, Holland PW, Ratcliffe PJ, Scho fi eld CJ (2011) The hypoxiainducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens. EMBO Rep 12:63-70
-
(2011)
EMBO Rep
, vol.12
, pp. 63-70
-
-
Loenarz, C.1
Coleman, M.L.2
Boleininger, A.3
Schierwater, B.4
Holland, P.W.5
Ratcliffe, P.J.6
Schofield, C.J.7
-
22
-
-
59049086571
-
Intermittent hypoxia degrades HIF-2 a via calpains resulting in oxidative stress: Implications for recurrent apneainduced morbidities
-
Nanduri J, Wang N, Yuan G, Khan SA, Souvannakitti D, Peng YJ, Kumar GK, Garcia JA, Prabhakar NR (2009 Intermittent hypoxia degrades HIF-2 a via calpains resulting in oxidative stress: Implications for recurrent apneainduced morbidities. Proc Natl Acad Sci U S A 106:1199-1204
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1199-1204
-
-
Nanduri, J.1
Wang, N.2
Yuan, G.3
Khan, S.A.4
Souvannakitti, D.5
Peng, Y.J.6
Kumar, G.K.7
Garcia, J.A.8
Prabhakar, N.R.9
-
23
-
-
0343362699
-
Association of sleep-disordered breathing, sleep apnea, and hypertension in a large communitybased study, Sleep Heart Health Study
-
Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, D'Agostino RB, Newman AB, Lebowitz MD, Pickering TG, Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, D'Agostino RB, Newman AB, Lebowitz MD, Pickering TG (2000) Association of sleep-disordered breathing, sleep apnea, and hypertension in a large communitybased study, Sleep Heart Health Study. JAMA 283:1829-1836
-
(2000)
JAMA
, vol.283
, pp. 1829-1836
-
-
Nieto, F.J.1
Young, T.B.2
Lind, B.K.3
Shahar, E.4
Samet, J.M.5
Redline, S.6
D'Agostino, R.B.7
Newman, A.B.8
Lebowitz, M.D.9
Pickering, T.G.10
Nieto, F.J.11
Young, T.B.12
Lind, B.K.13
Shahar, E.14
Samet, J.M.15
Redline, S.16
D'Agostino, R.B.17
Newman, A.B.18
Lebowitz, M.D.19
Pickering, T.G.20
more..
-
24
-
-
33751329032
-
Heterozygous HIF-1 a de fi ciency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
-
Peng Y, Yuan G, Ramakrishnan D, Sharma SD, Bosch-Marcé M, Kumar GK, Semenza GL, Prabhakar NR (2006 Heterozygous HIF-1 a de fi ciency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. J Physiol 577:705-716
-
(2006)
J Physiol
, vol.577
, pp. 705-716
-
-
Peng, Y.1
Yuan, G.2
Ramakrishnan, D.3
Sharma, S.D.4
Bosch-Marcé, M.5
Kumar, G.K.6
Semenza, G.L.7
Prabhakar, N.R.8
-
25
-
-
65549160457
-
NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia
-
Peng YJ, Nanduri J, Yuan G, Wang N, Deneris E, Pendyala S, Natarajan V, Kumar GK, Prabhakar NR (2009) NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia. J Neurosci 4903-4910
-
(2009)
J Neurosci
, pp. 4903-4910
-
-
Peng, Y.J.1
Nanduri, J.2
Yuan, G.3
Wang, N.4
Deneris, E.5
Pendyala, S.6
Natarajan, V.7
Kumar, G.K.8
Prabhakar, N.R.9
-
26
-
-
79952609061
-
Hypoxia-inducible factor 2 a (HIF-2 a) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
-
Peng Y, Nanduri J, Khan SA, Yuan G, Wang N, Kinsman B, Vaddi DR, umar GK, Garcia JA, Semenza GL, Prabhakar NR (2011) Hypoxia-inducible factor 2 a (HIF-2 a) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proc Natl Acad Sci U S A 108:3065-3070
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3065-3070
-
-
Peng, Y.1
Nanduri, J.2
Khan, S.A.3
Yuan, G.4
Wang, N.5
Kinsman, B.6
Vaddi, D.R.7
Umar, G.K.8
Garcia, J.A.9
Semenza, G.L.10
Prabhakar, N.R.11
-
27
-
-
0034636477
-
Prospective study of the association between sleep disordered breathing and hypertension
-
Peppard PE, Young T, Palta M, Skatrud J (2000) Prospective study of the association between sleep disordered breathing and hypertension. N Engl J Med 342:1378-1384
-
(2000)
N Engl J Med
, vol.342
, pp. 1378-1384
-
-
Peppard, P.E.1
Young, T.2
Palta, M.3
Skatrud, J.4
-
28
-
-
20344369336
-
Cardiovascular alterations by chronic intermittent hypoxia: Importance of carotid body chemore fl exes
-
Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE (2005) Cardiovascular alterations by chronic intermittent hypoxia: Importance of carotid body chemore fl exes. Clin Exp Pharmacol Physiol 32:447-449
-
(2005)
Clin Exp Pharmacol Physiol
, vol.32
, pp. 447-449
-
-
Prabhakar, N.R.1
Peng, Y.J.2
Jacono, F.J.3
Kumar, G.K.4
Dick, T.E.5
-
29
-
-
33846253979
-
Systemic, cellular and molecular analysis of chemore fl exmediated sympathoexcitation by chronic intermittent hypoxia
-
Prabhakar NR, Dick TE, Nanduri J, Kumar GK (2007a) Systemic, cellular and molecular analysis of chemore fl exmediated sympathoexcitation by chronic intermittent hypoxia. Exp Physiol 92:39-44
-
(2007)
Exp Physiol
, vol.92
, pp. 39-44
-
-
Prabhakar, N.R.1
Dick, T.E.2
Nanduri, J.3
Kumar, G.K.4
-
31
-
-
0032100732
-
HIF-1 a is required for solid tumor formation and embryonic vascularization
-
Ryan HE, Lo J, Johnson RS (1998) HIF-1 a is required for solid tumor formation and embryonic vascularization. EMBO J 17:3005-3015
-
(1998)
EMBO J
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
32
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
Semenza GL (2009) Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology (Bethesda 97-106
-
(2009)
Physiology (Bethesda
, pp. 97-106
-
-
Semenza, G.L.1
-
34
-
-
0035148723
-
Sleep-disordered breathing and cardiovascular disease
-
Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Nieto J, O'Connor GT, Boland LL, Schwartz JE, Samet JM (2001) Sleep-disordered breathing and cardiovascular disease. Am J Respir Crit Care Med 163:19-25
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 19-25
-
-
Shahar, E.1
Whitney, C.W.2
Redline, S.3
Lee, E.T.4
Newman, A.B.5
Nieto, J.6
O'Connor, G.T.7
Boland, L.L.8
Schwartz, J.E.9
Samet, J.M.10
-
35
-
-
0034815688
-
Partial HIF-1 a de fi ciency impairs pulmonary arterial myocyte electrophysiological responses to chronic hypoxia
-
Shimoda LA, Manalo DJ, Sham JSK, Semenza GL, Sylvester JT (2001) Partial HIF-1 a de fi ciency impairs pulmonary arterial myocyte electrophysiological responses to chronic hypoxia. Am J Physiol 281:L202-L208
-
(2001)
Am J Physiol
, vol.281
-
-
Shimoda, L.A.1
Manalo, D.J.2
Sham, J.S.K.3
Semenza, G.L.4
Sylvester, J.T.5
-
36
-
-
33751117499
-
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
-
Shimoda LA, Fallon M, Pisarcik S, Wang J, Semenza GL (2006) HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes. Am J Physiol 291:941-949
-
(2006)
Am J Physiol
, vol.291
, pp. 941-949
-
-
Shimoda, L.A.1
Fallon, M.2
Pisarcik, S.3
Wang, J.4
Semenza, G.L.5
-
38
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
Tian H, McKnight SL, Russell DW (1997) Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11:72-82
-
(1997)
Genes Dev
, vol.11
, pp. 72-82
-
-
Tian, H.1
McKnight, S.L.2
Russell, D.W.3
-
39
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1230-1237
-
(1995)
J Biol Chem
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
40
-
-
0029051439
-
Hypoxia-inducible actor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O 2 tension
-
Wang GL, Jiang B-H, Rue EA, Semenza GL (1995) Hypoxia-inducible actor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O 2 tension. Proc Natl Acad Sci U S A 92:5510-5514
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.-H.2
Rue, E.A.3
Semenza, G.L.4
-
41
-
-
39149127581
-
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K + channel expression in pulmonary arterial myocytes
-
Whitman EM, Pisarcik S, Luke T, Fallon M, Wang J, Sylvester JT, Semenza GL, Shimoda LA (2008) Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K + channel expression in pulmonary arterial myocytes. Am J Physiol 294:309-310
-
(2008)
Am J Physiol
, vol.294
, pp. 309-310
-
-
Whitman, E.M.1
Pisarcik, S.2
Luke, T.3
Fallon, M.4
Wang, J.5
Sylvester, J.T.6
Semenza, G.L.7
Shimoda, L.A.8
-
42
-
-
0032189844
-
Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor 1 a
-
Wiesener MS, Turley H, Allen WE, Willam C, Eckardt KU, Talks KL, Wood SM, Gatter KC, Harris AL, Pugh CW, Ratcliffe PJ, Maxwell PH (1998) Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor 1 a . Blood 92:2260-2268
-
(1998)
Blood
, vol.92
, pp. 2260-2268
-
-
Wiesener, M.S.1
Turley, H.2
Allen, W.E.3
Willam, C.4
Eckardt, K.U.5
Talks, K.L.6
Wood, S.M.7
Gatter, K.C.8
Harris, A.L.9
Pugh, C.W.10
Ratcliffe, P.J.11
Maxwell, P.H.12
-
43
-
-
33748742457
-
HIF-1 a de fi ciency results in dysregulated EPO signaling and iron homeostasis in mouse development
-
Yoon D, Pastore YD, Divoky V, Liu E, Mlodnicka AE, Rainey K, Ponka P, Semenza GL, Schumacher A, Prchal JT (2006) HIF-1 a de fi ciency results in dysregulated EPO signaling and iron homeostasis in mouse development. J Biol Chem 281:25703-25711
-
(2006)
J Biol Chem
, vol.281
, pp. 25703-25711
-
-
Yoon, D.1
Pastore, Y.D.2
Divoky, V.3
Liu, E.4
Mlodnicka, A.E.5
Rainey, K.6
Ponka, P.7
Semenza, G.L.8
Schumacher, A.9
Prchal, J.T.10
-
44
-
-
0033104847
-
Impaired physiological responses to chronic hypoxia in mice partially de fi cient for hypoxiainducible factor 1 a .
-
Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, McWilliams R, Beaty T, Sham JSK, Wiener CM, Sylvester JT, Semenza GL (1999) Impaired physiological responses to chronic hypoxia in mice partially de fi cient for hypoxiainducible factor 1 a . J Clin Invest 103:691-696
-
(1999)
J Clin Invest
, vol.103
, pp. 691-696
-
-
Yu, A.Y.1
Shimoda, L.A.2
Iyer, N.V.3
Huso, D.L.4
Sun, X.5
McWilliams, R.6
Beaty, T.7
Sham, J.S.K.8
Wiener, C.M.9
Sylvester, J.T.10
Semenza, G.L.11
-
45
-
-
14244256421
-
Ca 2+ /calmodulin kinase-dependent activation of hypoxia-inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia
-
Yuan G, Nanduri J, Bhasker RC, Semenza GL, Prabhakar NR (2005) Ca 2+ /calmodulin kinase-dependent activation of hypoxia-inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 4321-4328
-
(2005)
J Biol Chem
-
-
Yuan, G.1
Nanduri, J.2
Bhasker, R.C.3
Semenza, G.L.4
Prabhakar, N.R.5
-
46
-
-
54049088213
-
Induction of HIF-1 a expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca 2+ signaling, prolyl hydroxylases, and mTOR
-
4321-4328 Yuan G, Nanduri J, Khan S, Semenza GL, Prabhakar NR (2008) nduction of HIF-1 a expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca 2+ signaling, prolyl hydroxylases, and mTOR. J Cell Physiol 217:674-685
-
(2008)
J Cell Physiol
, vol.217
, pp. 674-685
-
-
Yuan, G.1
Nanduri, J.2
Khan, S.3
Semenza, G.L.4
Prabhakar, N.R.5
-
47
-
-
79960697192
-
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia
-
10.1002/jcp.22640, 2011 Feb 1 [ Epub ahead of print]
-
Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, Prabhakar NR (2011) Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol. doi: 10.1002/jcp.22640, 2011 Feb 1 [Epub ahead of print]
-
(2011)
J Cell Physiol
-
-
Yuan, G.1
Khan, S.A.2
Luo, W.3
Nanduri, J.4
Semenza, G.L.5
Prabhakar, N.R.6
-
48
-
-
25444437443
-
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea
-
Zhan G, Serrano F, Fenik P, Hsu R, Kong L, Pratico D, Klann E, Veasey SC (2005) NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea. Am J Respir Crit Care Med 172:921-929
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 921-929
-
-
Zhan, G.1
Serrano, F.2
Fenik, P.3
Hsu, R.4
Kong, L.5
Pratico, D.6
Klann, E.7
Veasey, S.C.8
-
49
-
-
77949902408
-
Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1 a heterozygous-null mice after burn wounding
-
Zhang X, Liu L, Wei X, Tan YS, Tong L, Chang R, Ghanamah MS, Reinblatt M, Marti GP, Harmon JW, Semenza GL (2010) Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1 a heterozygous-null mice after burn wounding. Wound Repair Regen 18:193-201
-
(2010)
Wound Repair Regen
, vol.18
, pp. 193-201
-
-
Zhang, X.1
Liu, L.2
Wei, X.3
Tan, Y.S.4
Tong, L.5
Chang, R.6
Ghanamah, M.S.7
Reinblatt, M.8
Marti, G.P.9
Harmon, J.W.10
Semenza, G.L.11
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