Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development

Journal of Biological Chemistry

Volumn 281, Issue 35, 2006, Pages 25703-25711

  Yoon, Donghoon ^a   Pastore, Yves D ^b   Divoky, Vladimir ^c   Liu, Enli ^d   Mlodnicka, Agnieszka E ^e   Rainey, Karin ^f   Ponka, Premysl ^g   Semenza, Gregg L ^f   Schumacher, Armin ^e   Prchal, Josef T ^a  

^a UNIVERSITY OF UTAH   (United States)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c PALACKÝ UNIVERSITY   (Czech Republic)

^d CENTER FOR CELL AND GENE THERAPY   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; LIVING SYSTEMS STUDIES; METABOLISM; MOLECULAR BIOLOGY; RNA;

ERYTHROPOIESIS; HOMOZYGOSITY; NEURAL MALFORMATIONS;

GENES;

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; HEMOGLOBIN; HEPCIDIN; HYPOXIA INDUCIBLE FACTOR 1; IRON; IRON BINDING PROTEIN; ISOPROTEIN; MESSENGER RNA; VASCULOTROPIN; WNT2 PROTEIN;

ANIMAL CELL; ANIMAL EMBRYO; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CULTURE; CONTROLLED STUDY; DYSERYTHROPOIESIS; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROID CELL; FEMALE; FUNCTIONAL PROTEOMICS; GENE EXPRESSION; HEMATOPOIESIS; IRON BALANCE; IRON METABOLISM DISORDER; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; YOLK SAC;

ANIMALS; ERYTHROPOIESIS; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HEMOGLOBINS; HYPOXIA-INDUCIBLE FACTOR 1; IRON; MICE; MICE, INBRED C57BL; RECEPTORS, ERYTHROPOIETIN; SIGNAL TRANSDUCTION; STEM CELLS; YOLK SAC;

MAMMALIA;

EID: 33748742457     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602329200     Document Type: Article

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