Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia

Journal of Physiology

Volumn 577, Issue 2, 2006, Pages 705-716

  Peng, Ying Jie ^a   Yuan, Guoxiang ^a   Ramakrishnan, Deviprasadh ^b   Sharma, Suresh D ^b   Bosch Marce, Marta ^c   Kumar, Ganesh K ^b   Semenza, Gregg L ^c   Prabhakar, Nanduri R ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; NORADRENALIN; REACTIVE OXYGEN METABOLITE; MANGANESE TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN PENTACHLORIDE; SCAVENGER; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; HIF1A PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE; BREATHING; CARDIOPULMONARY FUNCTION; CAROTID BODY CHEMORECEPTOR; CONTROLLED STUDY; HYPOXIA; MALE; MOUSE; NONHUMAN; NORADRENALIN BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ACUTE INTERMITTENT HYPOXIA; CARDIORESPIRATORY RESPONSE; CAROTID BODY; CHEMORECEPTOR; CHRONIC INTERMITTENT HYPOXIA; EVOKED RESPONSE; FACILITATION; HETEROZYGOTE; HYPERCAPNIA; HYPOXIC VENTILATORY RESPONSE; INTERMITTENT HYPOXIA; RESPIRATORY FUNCTION; SENSORY LONG TERM FACILITATION; UPREGULATION; ACTION POTENTIAL; ANIMAL; ANOXIA; BLOOD; BRAIN CORTEX; CARDIOVASCULAR FUNCTION; GENETICS; LUNG VENTILATION; METABOLISM; NERVE CELL PLASTICITY; NERVE CONDUCTION; PATHOPHYSIOLOGY; PHRENIC NERVE; REFLEX; TIME; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; ANOXIA; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGY; CAROTID BODY; CEREBRAL CORTEX; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MICE; MICE, TRANSGENIC; NEURAL CONDUCTION; NEURONAL PLASTICITY; NOREPINEPHRINE; PHRENIC NERVE; PULMONARY VENTILATION; REACTIVE OXYGEN SPECIES; REFLEX; RESPIRATORY PHYSIOLOGY; TIME FACTORS;

EID: 33751329032     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.114033     Document Type: Article

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