메뉴 건너뛰기




Volumn 99, Issue , 2013, Pages 25-31

Effects of a metabotropic glutamate receptor 5 positive allosteric modulator, CDPPB, on spatial learning task performance in rodents

Author keywords

Barnes maze; CDPPB; Metabotropic glutamate receptor 5; Spatial learning; T maze

Indexed keywords

3 CYANO N (1,3 DIPHENYL 1H HYDRAZOL 5 YL)BENZAMIDE; METABOTROPIC RECEPTOR 6; NOOTROPIC AGENT; UNCLASSIFIED DRUG;

EID: 84870387353     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2012.10.010     Document Type: Article
Times cited : (45)

References (38)
  • 2
    • 0035124349 scopus 로고    scopus 로고
    • Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
    • Attucci S., Carla V., Mannaioni G., Moroni F. Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. British Journal of Pharmacology 2001, 132:799-806.
    • (2001) British Journal of Pharmacology , vol.132 , pp. 799-806
    • Attucci, S.1    Carla, V.2    Mannaioni, G.3    Moroni, F.4
  • 3
    • 67651087294 scopus 로고    scopus 로고
    • MGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning
    • Ayala J.E., Chen Y., Banko J.L., Sheffler D.J., Williams R., Telk A.N., et al. MGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology 2009, 34:2057-2071.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2057-2071
    • Ayala, J.E.1    Chen, Y.2    Banko, J.L.3    Sheffler, D.J.4    Williams, R.5    Telk, A.N.6
  • 4
    • 0035996371 scopus 로고    scopus 로고
    • Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats
    • Balschun D., Wetzel W. Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats. Pharmacology, Biochemistry and Behavior 2002, 73(2):375-380.
    • (2002) Pharmacology, Biochemistry and Behavior , vol.73 , Issue.2 , pp. 375-380
    • Balschun, D.1    Wetzel, W.2
  • 5
    • 33749245129 scopus 로고    scopus 로고
    • Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory
    • Balschun D., Zuschratter W., Wetzel W. Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory. Neuroscience 2006, 142:691-702.
    • (2006) Neuroscience , vol.142 , pp. 691-702
    • Balschun, D.1    Zuschratter, W.2    Wetzel, W.3
  • 7
    • 43449131567 scopus 로고    scopus 로고
    • Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm
    • Darrah J.M., Stefani M.R., Moghaddam B. Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm. Behavioural Pharmacology 2008, 19:225-234.
    • (2008) Behavioural Pharmacology , vol.19 , pp. 225-234
    • Darrah, J.M.1    Stefani, M.R.2    Moghaddam, B.3
  • 9
    • 0036771838 scopus 로고    scopus 로고
    • Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine
    • Franowicz J.S., Kessler L.E., Borja C.M., Kobilka B.K., Limbird L.E., Arnsten A.F. Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. Journal of Neuroscience 2002, 22:8771-8777.
    • (2002) Journal of Neuroscience , vol.22 , pp. 8771-8777
    • Franowicz, J.S.1    Kessler, L.E.2    Borja, C.M.3    Kobilka, B.K.4    Limbird, L.E.5    Arnsten, A.F.6
  • 11
    • 77953615107 scopus 로고    scopus 로고
    • Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition
    • Homayoun H., Moghaddam B. Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition. European Journal of Pharmacology 2010, 639:33-39.
    • (2010) European Journal of Pharmacology , vol.639 , pp. 33-39
    • Homayoun, H.1    Moghaddam, B.2
  • 12
    • 2942650911 scopus 로고    scopus 로고
    • Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release
    • Homayoun H., Stefani M.R., Adams B.W., Tamagan G.D., Moghaddam B. Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release. Neuropsychopharmacology 2004, 29:1259-1269.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1259-1269
    • Homayoun, H.1    Stefani, M.R.2    Adams, B.W.3    Tamagan, G.D.4    Moghaddam, B.5
  • 14
    • 0032543202 scopus 로고    scopus 로고
    • Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats
    • Kishi A., Ohno M., Watanabe S. Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats. Brain Research 1998, 793:311-314.
    • (1998) Brain Research , vol.793 , pp. 311-314
    • Kishi, A.1    Ohno, M.2    Watanabe, S.3
  • 15
    • 34548506012 scopus 로고    scopus 로고
    • Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex
    • Lecourtier L., Homayoun H., Tamagnan G., Moghaddam B. Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex. Biological Psychiatry 2007, 62:739-746.
    • (2007) Biological Psychiatry , vol.62 , pp. 739-746
    • Lecourtier, L.1    Homayoun, H.2    Tamagnan, G.3    Moghaddam, B.4
  • 16
    • 57349174038 scopus 로고    scopus 로고
    • ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piper idin-1-yl}-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities
    • Liu F., Grauer S., Kelley C., Navarra R., Graf R., Zhang G., et al. ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piper idin-1-yl}-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. Journal of Pharmacology and Experimental Therapeutics 2008, 327:827-839.
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.327 , pp. 827-839
    • Liu, F.1    Grauer, S.2    Kelley, C.3    Navarra, R.4    Graf, R.5    Zhang, G.6
  • 17
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • Lu Y.M., Jia Z., Janus C., Henderson J.T., Gerlai R., Wojtowicz J.M., et al. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. Journal of Neuroscience 1997, 17:5196-5205.
    • (1997) Journal of Neuroscience , vol.17 , pp. 5196-5205
    • Lu, Y.M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6
  • 18
    • 84872130493 scopus 로고    scopus 로고
    • Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning
    • in press.
    • Mukherjee, S., & Manahan-Vaughan, D. (2012). Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning. Neuropharmacology, in press.
    • (2012) Neuropharmacology
    • Mukherjee, S.1    Manahan-Vaughan, D.2
  • 19
    • 0942290621 scopus 로고    scopus 로고
    • Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: Relevance for learning and memory formation
    • Naie K., Manahan-Vaughan D. Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: Relevance for learning and memory formation. Cerebral Cortex 2004, 14:189-198.
    • (2004) Cerebral Cortex , vol.14 , pp. 189-198
    • Naie, K.1    Manahan-Vaughan, D.2
  • 21
  • 22
    • 0029655407 scopus 로고    scopus 로고
    • Concurrent blockade of hippocampal metabotropic glutamate and N-methyl-D-aspartate receptors disrupts working memory in the rat
    • Ohno M., Watanabe S. Concurrent blockade of hippocampal metabotropic glutamate and N-methyl-D-aspartate receptors disrupts working memory in the rat. Neuroscience 1996, 70:303-311.
    • (1996) Neuroscience , vol.70 , pp. 303-311
    • Ohno, M.1    Watanabe, S.2
  • 23
    • 81455161631 scopus 로고    scopus 로고
    • The effects of apparatus design and test procedure on learning and memory performance of C57BL/6J mice on the Barnes maze
    • O'Leary T.P., Brown R.E. The effects of apparatus design and test procedure on learning and memory performance of C57BL/6J mice on the Barnes maze. Journal of Neuroscience Methods 2012, 203:315-324.
    • (2012) Journal of Neuroscience Methods , vol.203 , pp. 315-324
    • O'Leary, T.P.1    Brown, R.E.2
  • 24
    • 78149496335 scopus 로고    scopus 로고
    • Learning, memory and search strategies of inbred mouse strains with different visual abilities in the Barnes maze
    • O'Leary T.P., Savoie V., Brown R.E. Learning, memory and search strategies of inbred mouse strains with different visual abilities in the Barnes maze. Behavioural Brain Research 2011, 216:531-542.
    • (2011) Behavioural Brain Research , vol.216 , pp. 531-542
    • O'Leary, T.P.1    Savoie, V.2    Brown, R.E.3
  • 25
    • 78649785280 scopus 로고    scopus 로고
    • Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5)
    • Olsen C.M., Childs D.S., Stanwood G.D., Winder D.G. Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5). PLoS ONE 2010, 5:e15085.
    • (2010) PLoS ONE , vol.5
    • Olsen, C.M.1    Childs, D.S.2    Stanwood, G.D.3    Winder, D.G.4
  • 26
    • 80052166631 scopus 로고    scopus 로고
    • Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome
    • Pacey L.K., Tharmalingam S., Hampson D.R. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. Journal of Pharmacology and Experimental Therapeutics 2011, 338:897-905.
    • (2011) Journal of Pharmacology and Experimental Therapeutics , vol.338 , pp. 897-905
    • Pacey, L.K.1    Tharmalingam, S.2    Hampson, D.R.3
  • 27
    • 84856091327 scopus 로고    scopus 로고
    • Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration
    • Parmentier-Batteur S., Obrien J.A., Doran S., Nguyen S.J., Rosemarie B.F., Uslaner J.M., et al. Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration. Neuropharmacology 2010, 62:1453-1460.
    • (2010) Neuropharmacology , vol.62 , pp. 1453-1460
    • Parmentier-Batteur, S.1    Obrien, J.A.2    Doran, S.3    Nguyen, S.J.4    Rosemarie, B.F.5    Uslaner, J.M.6
  • 28
    • 13244264871 scopus 로고    scopus 로고
    • Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
    • Rodrigues R.J., Alfaro T.M., Rebola N., Oliveira C.R., Cunha R.A. Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. Journal of Neurochemistry 2005, 92:433-441.
    • (2005) Journal of Neurochemistry , vol.92 , pp. 433-441
    • Rodrigues, R.J.1    Alfaro, T.M.2    Rebola, N.3    Oliveira, C.R.4    Cunha, R.A.5
  • 29
    • 30444460573 scopus 로고    scopus 로고
    • The role of metabotropic glutamate receptor 5 in learning and memory processes
    • Simonyi A., Schachtman T.R., Christoffersen G.R. The role of metabotropic glutamate receptor 5 in learning and memory processes. Drug News and Perspectives 2005, 18:353-361.
    • (2005) Drug News and Perspectives , vol.18 , pp. 353-361
    • Simonyi, A.1    Schachtman, T.R.2    Christoffersen, G.R.3
  • 31
    • 80051728277 scopus 로고    scopus 로고
    • Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGlu(5))
    • Stauffer S.R. Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGlu(5)). ACS Chemical Neuroscience 2011, 2:450-470.
    • (2011) ACS Chemical Neuroscience , vol.2 , pp. 450-470
    • Stauffer, S.R.1
  • 33
    • 77953618942 scopus 로고    scopus 로고
    • Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade
    • Stefani M.R., Moghaddam B. Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade. European Journal of Pharmacology 2010, 639:26-32.
    • (2010) European Journal of Pharmacology , vol.639 , pp. 26-32
    • Stefani, M.R.1    Moghaddam, B.2
  • 34
    • 69649104858 scopus 로고    scopus 로고
    • Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
    • Uslaner J.M., Parmentier-Batteur S., Flick R.B., Surles N.O., Lam J.S., McNaughton C.H., et al. Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus. Neuropharmacology 2009, 57:531-538.
    • (2009) Neuropharmacology , vol.57 , pp. 531-538
    • Uslaner, J.M.1    Parmentier-Batteur, S.2    Flick, R.B.3    Surles, N.O.4    Lam, J.S.5    McNaughton, C.H.6
  • 36
    • 76949085425 scopus 로고    scopus 로고
    • MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?
    • Vardigan J.D., Huszar S.L., McNaughton C.H., Hutson P.H., Uslaner J.M. MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?. Pharmacology, Biochemistry and Behavior 2010, 95:223-229.
    • (2010) Pharmacology, Biochemistry and Behavior , vol.95 , pp. 223-229
    • Vardigan, J.D.1    Huszar, S.L.2    McNaughton, C.H.3    Hutson, P.H.4    Uslaner, J.M.5
  • 37
    • 79955085667 scopus 로고    scopus 로고
    • Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease
    • Walker J.M., Fowler S.W., Miller D.K., Sun A.Y., Weisman G.A., Wood W.G., et al. Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease. Behavioural Brain Research 2011, 222:169-175.
    • (2011) Behavioural Brain Research , vol.222 , pp. 169-175
    • Walker, J.M.1    Fowler, S.W.2    Miller, D.K.3    Sun, A.Y.4    Weisman, G.A.5    Wood, W.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.