-
1
-
-
0035996459
-
NMDA-induced phosphorylation and regulation of mGluR5
-
Alagarsamy S., Rouse S.T., Junge C., Hubert G.W., Gutman D., Smith Y., et al. NMDA-induced phosphorylation and regulation of mGluR5. Pharmacology, Biochemistry and Behavior 2002, 73:299-306.
-
(2002)
Pharmacology, Biochemistry and Behavior
, vol.73
, pp. 299-306
-
-
Alagarsamy, S.1
Rouse, S.T.2
Junge, C.3
Hubert, G.W.4
Gutman, D.5
Smith, Y.6
-
2
-
-
0035124349
-
Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
-
Attucci S., Carla V., Mannaioni G., Moroni F. Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. British Journal of Pharmacology 2001, 132:799-806.
-
(2001)
British Journal of Pharmacology
, vol.132
, pp. 799-806
-
-
Attucci, S.1
Carla, V.2
Mannaioni, G.3
Moroni, F.4
-
3
-
-
67651087294
-
MGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning
-
Ayala J.E., Chen Y., Banko J.L., Sheffler D.J., Williams R., Telk A.N., et al. MGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology 2009, 34:2057-2071.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2057-2071
-
-
Ayala, J.E.1
Chen, Y.2
Banko, J.L.3
Sheffler, D.J.4
Williams, R.5
Telk, A.N.6
-
4
-
-
0035996371
-
Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats
-
Balschun D., Wetzel W. Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats. Pharmacology, Biochemistry and Behavior 2002, 73(2):375-380.
-
(2002)
Pharmacology, Biochemistry and Behavior
, vol.73
, Issue.2
, pp. 375-380
-
-
Balschun, D.1
Wetzel, W.2
-
5
-
-
33749245129
-
Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory
-
Balschun D., Zuschratter W., Wetzel W. Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory. Neuroscience 2006, 142:691-702.
-
(2006)
Neuroscience
, vol.142
, pp. 691-702
-
-
Balschun, D.1
Zuschratter, W.2
Wetzel, W.3
-
6
-
-
43849090366
-
MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats
-
Christoffersen G.R., Simonyi A., Schachtman T.R., Clausen B., Clement D., Bjerre V.K., et al. MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats. Behavioural Brain Research 2008, 191:235-245.
-
(2008)
Behavioural Brain Research
, vol.191
, pp. 235-245
-
-
Christoffersen, G.R.1
Simonyi, A.2
Schachtman, T.R.3
Clausen, B.4
Clement, D.5
Bjerre, V.K.6
-
7
-
-
43449131567
-
Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm
-
Darrah J.M., Stefani M.R., Moghaddam B. Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm. Behavioural Pharmacology 2008, 19:225-234.
-
(2008)
Behavioural Pharmacology
, vol.19
, pp. 225-234
-
-
Darrah, J.M.1
Stefani, M.R.2
Moghaddam, B.3
-
8
-
-
78651237783
-
Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats
-
Fowler S.W., Ramsey A.K., Walker J.M., Serfozo P., Olive M.F., Schachtman T.R., et al. Functional interaction of mGlu5 and NMDA receptors in aversive learning in rats. Neurobiology of Learning and Memory 2010, 95:73-79.
-
(2010)
Neurobiology of Learning and Memory
, vol.95
, pp. 73-79
-
-
Fowler, S.W.1
Ramsey, A.K.2
Walker, J.M.3
Serfozo, P.4
Olive, M.F.5
Schachtman, T.R.6
-
9
-
-
0036771838
-
Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine
-
Franowicz J.S., Kessler L.E., Borja C.M., Kobilka B.K., Limbird L.E., Arnsten A.F. Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. Journal of Neuroscience 2002, 22:8771-8777.
-
(2002)
Journal of Neuroscience
, vol.22
, pp. 8771-8777
-
-
Franowicz, J.S.1
Kessler, L.E.2
Borja, C.M.3
Kobilka, B.K.4
Limbird, L.E.5
Arnsten, A.F.6
-
10
-
-
33845334169
-
Spatial and nonspatial escape strategies in the Barnes maze
-
Harrison F.E., Reiserer R.S., Tomarken A.J., McDonald M.P. Spatial and nonspatial escape strategies in the Barnes maze. Learning and Memory 2006, 13:809-819.
-
(2006)
Learning and Memory
, vol.13
, pp. 809-819
-
-
Harrison, F.E.1
Reiserer, R.S.2
Tomarken, A.J.3
McDonald, M.P.4
-
11
-
-
77953615107
-
Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition
-
Homayoun H., Moghaddam B. Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition. European Journal of Pharmacology 2010, 639:33-39.
-
(2010)
European Journal of Pharmacology
, vol.639
, pp. 33-39
-
-
Homayoun, H.1
Moghaddam, B.2
-
12
-
-
2942650911
-
Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release
-
Homayoun H., Stefani M.R., Adams B.W., Tamagan G.D., Moghaddam B. Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release. Neuropsychopharmacology 2004, 29:1259-1269.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1259-1269
-
-
Homayoun, H.1
Stefani, M.R.2
Adams, B.W.3
Tamagan, G.D.4
Moghaddam, B.5
-
13
-
-
79961013983
-
Disruption of adult expression of sexually selected traits by developmental exposure to bisphenol A
-
Jasarevic E., Sieli P.T., Twellman E.E., Welsh T.H., Schachtman T.R., Roberts R.M., et al. Disruption of adult expression of sexually selected traits by developmental exposure to bisphenol A. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:11715-11720.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 11715-11720
-
-
Jasarevic, E.1
Sieli, P.T.2
Twellman, E.E.3
Welsh, T.H.4
Schachtman, T.R.5
Roberts, R.M.6
-
14
-
-
0032543202
-
Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats
-
Kishi A., Ohno M., Watanabe S. Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats. Brain Research 1998, 793:311-314.
-
(1998)
Brain Research
, vol.793
, pp. 311-314
-
-
Kishi, A.1
Ohno, M.2
Watanabe, S.3
-
15
-
-
34548506012
-
Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex
-
Lecourtier L., Homayoun H., Tamagnan G., Moghaddam B. Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex. Biological Psychiatry 2007, 62:739-746.
-
(2007)
Biological Psychiatry
, vol.62
, pp. 739-746
-
-
Lecourtier, L.1
Homayoun, H.2
Tamagnan, G.3
Moghaddam, B.4
-
16
-
-
57349174038
-
ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piper idin-1-yl}-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities
-
Liu F., Grauer S., Kelley C., Navarra R., Graf R., Zhang G., et al. ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piper idin-1-yl}-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. Journal of Pharmacology and Experimental Therapeutics 2008, 327:827-839.
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.327
, pp. 827-839
-
-
Liu, F.1
Grauer, S.2
Kelley, C.3
Navarra, R.4
Graf, R.5
Zhang, G.6
-
17
-
-
0030954048
-
Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
-
Lu Y.M., Jia Z., Janus C., Henderson J.T., Gerlai R., Wojtowicz J.M., et al. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. Journal of Neuroscience 1997, 17:5196-5205.
-
(1997)
Journal of Neuroscience
, vol.17
, pp. 5196-5205
-
-
Lu, Y.M.1
Jia, Z.2
Janus, C.3
Henderson, J.T.4
Gerlai, R.5
Wojtowicz, J.M.6
-
18
-
-
84872130493
-
Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning
-
in press.
-
Mukherjee, S., & Manahan-Vaughan, D. (2012). Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning. Neuropharmacology, in press.
-
(2012)
Neuropharmacology
-
-
Mukherjee, S.1
Manahan-Vaughan, D.2
-
19
-
-
0942290621
-
Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: Relevance for learning and memory formation
-
Naie K., Manahan-Vaughan D. Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: Relevance for learning and memory formation. Cerebral Cortex 2004, 14:189-198.
-
(2004)
Cerebral Cortex
, vol.14
, pp. 189-198
-
-
Naie, K.1
Manahan-Vaughan, D.2
-
20
-
-
79954614494
-
Metabotropic glutamate receptors: From the workbench to the bedside
-
Nicoletti F., Bockaert J., Collingridge G.L., Conn P.J., Ferraguti F., Schoepp D.D., et al. Metabotropic glutamate receptors: From the workbench to the bedside. Neuropharmacology 2011, 60:1017-1041.
-
(2011)
Neuropharmacology
, vol.60
, pp. 1017-1041
-
-
Nicoletti, F.1
Bockaert, J.2
Collingridge, G.L.3
Conn, P.J.4
Ferraguti, F.5
Schoepp, D.D.6
-
21
-
-
77949516412
-
Metabotropic glutamate receptors: Physiology, pharmacology, and disease
-
Niswender C.M., Conn P.J. Metabotropic glutamate receptors: Physiology, pharmacology, and disease. Annual Review of Pharmacology and Toxicology 2010, 50:295-322.
-
(2010)
Annual Review of Pharmacology and Toxicology
, vol.50
, pp. 295-322
-
-
Niswender, C.M.1
Conn, P.J.2
-
22
-
-
0029655407
-
Concurrent blockade of hippocampal metabotropic glutamate and N-methyl-D-aspartate receptors disrupts working memory in the rat
-
Ohno M., Watanabe S. Concurrent blockade of hippocampal metabotropic glutamate and N-methyl-D-aspartate receptors disrupts working memory in the rat. Neuroscience 1996, 70:303-311.
-
(1996)
Neuroscience
, vol.70
, pp. 303-311
-
-
Ohno, M.1
Watanabe, S.2
-
23
-
-
81455161631
-
The effects of apparatus design and test procedure on learning and memory performance of C57BL/6J mice on the Barnes maze
-
O'Leary T.P., Brown R.E. The effects of apparatus design and test procedure on learning and memory performance of C57BL/6J mice on the Barnes maze. Journal of Neuroscience Methods 2012, 203:315-324.
-
(2012)
Journal of Neuroscience Methods
, vol.203
, pp. 315-324
-
-
O'Leary, T.P.1
Brown, R.E.2
-
24
-
-
78149496335
-
Learning, memory and search strategies of inbred mouse strains with different visual abilities in the Barnes maze
-
O'Leary T.P., Savoie V., Brown R.E. Learning, memory and search strategies of inbred mouse strains with different visual abilities in the Barnes maze. Behavioural Brain Research 2011, 216:531-542.
-
(2011)
Behavioural Brain Research
, vol.216
, pp. 531-542
-
-
O'Leary, T.P.1
Savoie, V.2
Brown, R.E.3
-
25
-
-
78649785280
-
Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5)
-
Olsen C.M., Childs D.S., Stanwood G.D., Winder D.G. Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5). PLoS ONE 2010, 5:e15085.
-
(2010)
PLoS ONE
, vol.5
-
-
Olsen, C.M.1
Childs, D.S.2
Stanwood, G.D.3
Winder, D.G.4
-
26
-
-
80052166631
-
Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome
-
Pacey L.K., Tharmalingam S., Hampson D.R. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. Journal of Pharmacology and Experimental Therapeutics 2011, 338:897-905.
-
(2011)
Journal of Pharmacology and Experimental Therapeutics
, vol.338
, pp. 897-905
-
-
Pacey, L.K.1
Tharmalingam, S.2
Hampson, D.R.3
-
27
-
-
84856091327
-
Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration
-
Parmentier-Batteur S., Obrien J.A., Doran S., Nguyen S.J., Rosemarie B.F., Uslaner J.M., et al. Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration. Neuropharmacology 2010, 62:1453-1460.
-
(2010)
Neuropharmacology
, vol.62
, pp. 1453-1460
-
-
Parmentier-Batteur, S.1
Obrien, J.A.2
Doran, S.3
Nguyen, S.J.4
Rosemarie, B.F.5
Uslaner, J.M.6
-
28
-
-
13244264871
-
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
-
Rodrigues R.J., Alfaro T.M., Rebola N., Oliveira C.R., Cunha R.A. Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. Journal of Neurochemistry 2005, 92:433-441.
-
(2005)
Journal of Neurochemistry
, vol.92
, pp. 433-441
-
-
Rodrigues, R.J.1
Alfaro, T.M.2
Rebola, N.3
Oliveira, C.R.4
Cunha, R.A.5
-
31
-
-
80051728277
-
Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGlu(5))
-
Stauffer S.R. Progress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGlu(5)). ACS Chemical Neuroscience 2011, 2:450-470.
-
(2011)
ACS Chemical Neuroscience
, vol.2
, pp. 450-470
-
-
Stauffer, S.R.1
-
32
-
-
24344483151
-
Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial water maze task
-
Steckler T., Oliveira A.F., Van Dyck C., Van Craenendonck H., Mateus A.M., Langlois X., et al. Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial water maze task. Behavioural Brain Research 2005, 164:52-60.
-
(2005)
Behavioural Brain Research
, vol.164
, pp. 52-60
-
-
Steckler, T.1
Oliveira, A.F.2
Van Dyck, C.3
Van Craenendonck, H.4
Mateus, A.M.5
Langlois, X.6
-
33
-
-
77953618942
-
Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade
-
Stefani M.R., Moghaddam B. Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade. European Journal of Pharmacology 2010, 639:26-32.
-
(2010)
European Journal of Pharmacology
, vol.639
, pp. 26-32
-
-
Stefani, M.R.1
Moghaddam, B.2
-
34
-
-
69649104858
-
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
-
Uslaner J.M., Parmentier-Batteur S., Flick R.B., Surles N.O., Lam J.S., McNaughton C.H., et al. Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus. Neuropharmacology 2009, 57:531-538.
-
(2009)
Neuropharmacology
, vol.57
, pp. 531-538
-
-
Uslaner, J.M.1
Parmentier-Batteur, S.2
Flick, R.B.3
Surles, N.O.4
Lam, J.S.5
McNaughton, C.H.6
-
35
-
-
77953617941
-
The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801
-
Vales K., Svoboda J., Benkovicova K., Bubenikova-Valesova V., Stuchlik A. The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801. European Journal of Pharmacology 2010, 639:91-98.
-
(2010)
European Journal of Pharmacology
, vol.639
, pp. 91-98
-
-
Vales, K.1
Svoboda, J.2
Benkovicova, K.3
Bubenikova-Valesova, V.4
Stuchlik, A.5
-
36
-
-
76949085425
-
MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?
-
Vardigan J.D., Huszar S.L., McNaughton C.H., Hutson P.H., Uslaner J.M. MK-801 produces a deficit in sucrose preference that is reversed by clozapine, D-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?. Pharmacology, Biochemistry and Behavior 2010, 95:223-229.
-
(2010)
Pharmacology, Biochemistry and Behavior
, vol.95
, pp. 223-229
-
-
Vardigan, J.D.1
Huszar, S.L.2
McNaughton, C.H.3
Hutson, P.H.4
Uslaner, J.M.5
-
37
-
-
79955085667
-
Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease
-
Walker J.M., Fowler S.W., Miller D.K., Sun A.Y., Weisman G.A., Wood W.G., et al. Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease. Behavioural Brain Research 2011, 222:169-175.
-
(2011)
Behavioural Brain Research
, vol.222
, pp. 169-175
-
-
Walker, J.M.1
Fowler, S.W.2
Miller, D.K.3
Sun, A.Y.4
Weisman, G.A.5
Wood, W.G.6
-
38
-
-
64849110971
-
MGluR5 has a critical role in inhibitory learning
-
Xu J., Zhu Y., Contractor A., Heinemann S.F. MGluR5 has a critical role in inhibitory learning. Journal of Neuroscience 2009, 29:3676-3684.
-
(2009)
Journal of Neuroscience
, vol.29
, pp. 3676-3684
-
-
Xu, J.1
Zhu, Y.2
Contractor, A.3
Heinemann, S.F.4
|