메뉴 건너뛰기




Volumn 639, Issue 1-3, 2010, Pages 26-32

Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade

Author keywords

Addiction; Extradimensional shift; Perseveration; Prefrontal cortex; Response inhibition; Schizophrenia; Set shift

Indexed keywords

3 CYANO N (1,3 DIPHENYL 1H PYRAZOL 5 YL)BENZAMIDE; DIZOCILPINE; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG; 3-CYANO-N-(1,3-DIPHENYL-1H-PYRAZOL-5-YL)BENZAMIDE; AMINO ACID RECEPTOR BLOCKING AGENT; BENZAMIDE DERIVATIVE; DIZOCILPINE MALEATE; METABOTROPIC RECEPTOR; PYRAZOLE DERIVATIVE;

EID: 77953618942     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.01.028     Document Type: Article
Times cited : (92)

References (52)
  • 2
    • 0035145915 scopus 로고    scopus 로고
    • Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task
    • Aultman J.M., Moghaddam B. Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task. Psychopharmacologia 2001, 153:353-364.
    • (2001) Psychopharmacologia , vol.153 , pp. 353-364
    • Aultman, J.M.1    Moghaddam, B.2
  • 3
    • 0034332480 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
    • Awad H., Hubert G.W., Smith Y., Levey A.I., Conn P.J. Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J. Neurosci. 2000, 20:7871-7879.
    • (2000) J. Neurosci. , vol.20 , pp. 7871-7879
    • Awad, H.1    Hubert, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 5
    • 0032511075 scopus 로고    scopus 로고
    • Inhibition of group I metabotropic glutamate receptors blocks spatial learning in rats
    • Balschun D., Wetzel W. Inhibition of group I metabotropic glutamate receptors blocks spatial learning in rats. Neurosci. Lett. 1998, 249:41-44.
    • (1998) Neurosci. Lett. , vol.249 , pp. 41-44
    • Balschun, D.1    Wetzel, W.2
  • 6
    • 33749245129 scopus 로고    scopus 로고
    • Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory
    • Balschun D., Zuschratter W., Wetzel W. Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory. Neuroscience 2006, 142:691-702.
    • (2006) Neuroscience , vol.142 , pp. 691-702
    • Balschun, D.1    Zuschratter, W.2    Wetzel, W.3
  • 7
    • 0027520283 scopus 로고
    • The metabotropic glutamate receptor (mGluR1a) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction
    • Baude A., Nusser Z., Roberts J.D.B., Mulvihill E., McIlhinney R.A.J., Somogyi P. The metabotropic glutamate receptor (mGluR1a) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 1993, 11:771-787.
    • (1993) Neuron , vol.11 , pp. 771-787
    • Baude, A.1    Nusser, Z.2    Roberts, J.D.B.3    Mulvihill, E.4    McIlhinney, R.A.J.5    Somogyi, P.6
  • 8
  • 9
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 2000, 20:4320-4324.
    • (2000) J. Neurosci. , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 10
    • 0027080086 scopus 로고
    • Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn
    • Bleakman D., Rusin K.I., Chard P.S., Glaum S.R., Miller R.J. Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn. Mol. Pharmacol. 1992, 42:192-196.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 192-196
    • Bleakman, D.1    Rusin, K.I.2    Chard, P.S.3    Glaum, S.R.4    Miller, R.J.5
  • 12
    • 55049123814 scopus 로고    scopus 로고
    • Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction
    • Carroll F.I. Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction. Ann. N. Y. Acad. Sci. 2008, 1141:221-232.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1141 , pp. 221-232
    • Carroll, F.I.1
  • 14
    • 0030894148 scopus 로고    scopus 로고
    • (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus
    • Doherty A.J., Palmer M.J., Henley J.M., Collingridge G.L., Jane D.E. (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 1997, 36:265-267.
    • (1997) Neuropharmacology , vol.36 , pp. 265-267
    • Doherty, A.J.1    Palmer, M.J.2    Henley, J.M.3    Collingridge, G.L.4    Jane, D.E.5
  • 15
    • 17744365167 scopus 로고    scopus 로고
    • Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia
    • Egerton A., Reid L., McKerchar C.E., Morris B.J., Pratt J.A. Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia. Psychopharmacology 2005, 179:77-84.
    • (2005) Psychopharmacology , vol.179 , pp. 77-84
    • Egerton, A.1    Reid, L.2    McKerchar, C.E.3    Morris, B.J.4    Pratt, J.A.5
  • 16
    • 0038699101 scopus 로고    scopus 로고
    • Homer as both a scaffold and transduction molecule
    • %R 10.1126/stke.2002.137.re8 2002
    • Fagni L., Worley P.F., Ango F. Homer as both a scaffold and transduction molecule. Sci. STKE 2002, re8- %R 10.1126/stke.2002.137.re8 2002.
    • (2002) Sci. STKE
    • Fagni, L.1    Worley, P.F.2    Ango, F.3
  • 17
    • 30944469609 scopus 로고    scopus 로고
    • Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting
    • Floresco S.B., Magyar O., Ghods-Sharifi S., Vexelman C., Tse M.T.L. Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting. Neuropsychopharmacology 2005, 31:297-309.
    • (2005) Neuropsychopharmacology , vol.31 , pp. 297-309
    • Floresco, S.B.1    Magyar, O.2    Ghods-Sharifi, S.3    Vexelman, C.4    Tse, M.T.L.5
  • 20
    • 2942650911 scopus 로고    scopus 로고
    • Functional interaction between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors and dopamine release
    • Homayoun H., Stefani M.R., Adams B.W., Tamagan G.D., Moghaddam B. Functional interaction between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors and dopamine release. Neuropsychopharmacology 2004, 29:1259-1269.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1259-1269
    • Homayoun, H.1    Stefani, M.R.2    Adams, B.W.3    Tamagan, G.D.4    Moghaddam, B.5
  • 21
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 1991, 148:1301-1308.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 22
    • 0035205333 scopus 로고    scopus 로고
    • Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats
    • Jentsch J.D., Taylor J.R. Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats. Neuropsychopharmacology 2001, 24:66-74.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 66-74
    • Jentsch, J.D.1    Taylor, J.R.2
  • 23
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew J.N., Kemp J.A. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology (Berl.) 2005, 179:4-29.
    • (2005) Psychopharmacology (Berl.) , vol.179 , pp. 4-29
    • Kew, J.N.1    Kemp, J.A.2
  • 26
    • 78650575007 scopus 로고    scopus 로고
    • Pretreatment with group I metabotropic glutamate receptor antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice
    • Kotlinska J., Bochenski M. Pretreatment with group I metabotropic glutamate receptor antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice. Neurotox. Res. 2009, 10.1007/s12640-009-9136-8.
    • (2009) Neurotox. Res.
    • Kotlinska, J.1    Bochenski, M.2
  • 28
    • 34548506012 scopus 로고    scopus 로고
    • Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-methyl-d-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex
    • Lecourtier L., Homayoun H., Tamagnan G., Moghaddam B. Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-methyl-d-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex. Biol. Psychiatry 2007, 62:739-746.
    • (2007) Biol. Psychiatry , vol.62 , pp. 739-746
    • Lecourtier, L.1    Homayoun, H.2    Tamagnan, G.3    Moghaddam, B.4
  • 31
    • 0030704241 scopus 로고    scopus 로고
    • Differential plasma distribution of metabotropic glutamate receptors mGluR1a, mGluR2 and mGluR5, relative to neurotransmitter release sites
    • Luján R., Roberts J.D.B., Shigemoto R., Ohishi H., Somogyi P. Differential plasma distribution of metabotropic glutamate receptors mGluR1a, mGluR2 and mGluR5, relative to neurotransmitter release sites. J. Comp. Neuroanat. 1997, 13:219-241.
    • (1997) J. Comp. Neuroanat. , vol.13 , pp. 219-241
    • Luján, R.1    Roberts, J.D.B.2    Shigemoto, R.3    Ohishi, H.4    Somogyi, P.5
  • 32
    • 26844466906 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity
    • Manahan-Vaughn D., Braunewell K.-H. The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity. Cereb. Cortex 2005, 15:1703-1713.
    • (2005) Cereb. Cortex , vol.15 , pp. 1703-1713
    • Manahan-Vaughn, D.1    Braunewell, K.-H.2
  • 33
    • 0038798022 scopus 로고    scopus 로고
    • Direct and indirect modulation of the N-methyl d-aspartate receptor
    • Marino M.J., Conn P.J. Direct and indirect modulation of the N-methyl d-aspartate receptor. Curr. Drug Targets CNS Neurol. Disord. 2002, 1:1-16.
    • (2002) Curr. Drug Targets CNS Neurol. Disord. , vol.1 , pp. 1-16
    • Marino, M.J.1    Conn, P.J.2
  • 34
    • 8444235461 scopus 로고    scopus 로고
    • Impoverished rearing environment alters metabotropic glutamate receptor expression and function in the prefrontal cortex
    • Melendez R.I., Gregory M.L., Bardo M.T., Kalivas P.W. Impoverished rearing environment alters metabotropic glutamate receptor expression and function in the prefrontal cortex. Neuropsychopharmacology 2004, 29:1980-1987.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1980-1987
    • Melendez, R.I.1    Gregory, M.L.2    Bardo, M.T.3    Kalivas, P.W.4
  • 35
    • 84887059933 scopus 로고
    • Effects of different brain lesions on card-sorting, the role of the frontal lobes
    • Milner B. Effects of different brain lesions on card-sorting, the role of the frontal lobes. Arch. Neurol. 1963, 9:90-100.
    • (1963) Arch. Neurol. , vol.9 , pp. 90-100
    • Milner, B.1
  • 36
    • 0346367105 scopus 로고    scopus 로고
    • Bringing order to the glutamate chaos in schizophrenia
    • Moghaddam B. Bringing order to the glutamate chaos in schizophrenia. Neuron 2003, 40:881-884.
    • (2003) Neuron , vol.40 , pp. 881-884
    • Moghaddam, B.1
  • 37
    • 3142739322 scopus 로고    scopus 로고
    • Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia
    • Moghaddam B. Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia. Psychopharmacology (Berl) 2004, 174:39-44.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 39-44
    • Moghaddam, B.1
  • 38
    • 0035072032 scopus 로고    scopus 로고
    • Task-dependent role for dorsal striatum metabotropic glutamate receptors in memory
    • Packard M.G., Vecchioli S.F., Schroeder J.P., Gasbarri A. Task-dependent role for dorsal striatum metabotropic glutamate receptors in memory. Learn. Mem. 2001, 8:96-103.
    • (2001) Learn. Mem. , vol.8 , pp. 96-103
    • Packard, M.G.1    Vecchioli, S.F.2    Schroeder, J.P.3    Gasbarri, A.4
  • 39
    • 17744369469 scopus 로고    scopus 로고
    • Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents
    • Page M.E., Szeliga P., Gasparini F., Cryan J.F. Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. Psychopharmacology 2005, 179:240-246.
    • (2005) Psychopharmacology , vol.179 , pp. 240-246
    • Page, M.E.1    Szeliga, P.2    Gasparini, F.3    Cryan, J.F.4
  • 40
    • 0001050066 scopus 로고    scopus 로고
    • The metabotropic glutamate receptors: structure, activation mechanism and pharmacology
    • Pin J.P., Acher F. The metabotropic glutamate receptors: structure, activation mechanism and pharmacology. Curr. Drug Targets CNS Neurol. Disord. 2002, 1:297-317.
    • (2002) Curr. Drug Targets CNS Neurol. Disord. , vol.1 , pp. 297-317
    • Pin, J.P.1    Acher, F.2
  • 41
    • 0033152379 scopus 로고    scopus 로고
    • Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning
    • Ragozzino M.E., Detrick S., Kesner R.P. Involvement of the prelimbic-infralimbic areas of the rodent prefrontal cortex in behavioral flexibility for place and response learning. J. Neurosci. 1999, 19:4585-4594.
    • (1999) J. Neurosci. , vol.19 , pp. 4585-4594
    • Ragozzino, M.E.1    Detrick, S.2    Kesner, R.P.3
  • 42
    • 0036146047 scopus 로고    scopus 로고
    • Role of the dorsomedial striatum in behavioral flexibility for response and visual cue discrimination learning
    • Ragozzino M.E., Ragozzino K.E., Mizumori J.J.Y., Kesner R.P. Role of the dorsomedial striatum in behavioral flexibility for response and visual cue discrimination learning. Behav. Neurosci. 2002, 116:105-115.
    • (2002) Behav. Neurosci. , vol.116 , pp. 105-115
    • Ragozzino, M.E.1    Ragozzino, K.E.2    Mizumori, J.J.Y.3    Kesner, R.P.4
  • 44
    • 33846862930 scopus 로고    scopus 로고
    • The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task
    • Semenova S., Markou A. The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task. Neuropharmacology 2007, 52:863-872.
    • (2007) Neuropharmacology , vol.52 , pp. 863-872
    • Semenova, S.1    Markou, A.2
  • 45
    • 58149442703 scopus 로고
    • Intradimensional and extradimensional shifts in the rat
    • Shepp B.E., Eimas P.D. Intradimensional and extradimensional shifts in the rat. J. Comp. Physiol. Psychol. 1964, 57:357-361.
    • (1964) J. Comp. Physiol. Psychol. , vol.57 , pp. 357-361
    • Shepp, B.E.1    Eimas, P.D.2
  • 46
    • 17444375268 scopus 로고    scopus 로고
    • Systemic and prefrontal cortical NMDA receptor blockade differentially affect discrimination learning and set-shift ability in rats
    • Stefani M.R., Moghaddam B. Systemic and prefrontal cortical NMDA receptor blockade differentially affect discrimination learning and set-shift ability in rats. Behav. Neurosci. 2005, 119:420-428.
    • (2005) Behav. Neurosci. , vol.119 , pp. 420-428
    • Stefani, M.R.1    Moghaddam, B.2
  • 47
    • 33748251667 scopus 로고    scopus 로고
    • Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum
    • Stefani M.R., Moghaddam B. Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum. J. Neurosci. 2006, 26:8810-8818.
    • (2006) J. Neurosci. , vol.26 , pp. 8810-8818
    • Stefani, M.R.1    Moghaddam, B.2
  • 48
    • 0042165944 scopus 로고    scopus 로고
    • Glutamate receptors in the rat medial prefrontal cortex regulate set-shifting ability
    • Stefani M.R., Groth K., Moghaddam B. Glutamate receptors in the rat medial prefrontal cortex regulate set-shifting ability. Behav. Neurosci. 2003, 117:728-737.
    • (2003) Behav. Neurosci. , vol.117 , pp. 728-737
    • Stefani, M.R.1    Groth, K.2    Moghaddam, B.3
  • 49
    • 0031979134 scopus 로고    scopus 로고
    • Schizophrenia and glutamatergic transmission
    • Tamminga C.A. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurobiol. 1998, 12:21-36.
    • (1998) Crit. Rev. Neurobiol. , vol.12 , pp. 21-36
    • Tamminga, C.A.1
  • 50
    • 69649104858 scopus 로고    scopus 로고
    • Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
    • Uslaner J.M., Parmentier-Batteur S., Flick R.B., Surles N.O., Lam J.S.H., McNaughton C.H., Jacobson M.A., Hutson P.H. Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus. Neuropharmacology 2009, 57:531-538.
    • (2009) Neuropharmacology , vol.57 , pp. 531-538
    • Uslaner, J.M.1    Parmentier-Batteur, S.2    Flick, R.B.3    Surles, N.O.4    Lam, J.S.H.5    McNaughton, C.H.6    Jacobson, M.A.7    Hutson, P.H.8
  • 51
    • 0033846992 scopus 로고    scopus 로고
    • Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies
    • Vanderschuren L.J.M.J., Kalivas P.W. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology (Berl.) 2000, 151:99-120.
    • (2000) Psychopharmacology (Berl.) , vol.151 , pp. 99-120
    • Vanderschuren, L.J.M.J.1    Kalivas, P.W.2
  • 52
    • 64849110971 scopus 로고    scopus 로고
    • MGluR5 has a critical role in inhibitory learning
    • Xu J., Zhu Y., Contractor A., Heinemann S.F. mGluR5 has a critical role in inhibitory learning. J. Neurosci. 2009, 29:3676-3684.
    • (2009) J. Neurosci. , vol.29 , pp. 3676-3684
    • Xu, J.1    Zhu, Y.2    Contractor, A.3    Heinemann, S.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.