-
1
-
-
0038035670
-
Paresis of a bone morphogenetic protein-antagonist response in a genetic disorder of heterotopic skeletogenesis
-
Ahn, J., Serrano de la Peña, L., Shore, E. M. and Kaplan, F. S. (2003). Paresis of a bone morphogenetic protein-antagonist response in a genetic disorder of heterotopic skeletogenesis. J. Bone Joint Surg. Am. 85, 667-674. (Pubitemid 36538716)
-
(2003)
Journal of Bone and Joint Surgery - Series A
, vol.85
, Issue.4
, pp. 667-674
-
-
Ahn, J.1
Serrano, D.L.P.L.2
Shore, E.M.3
Kaplan, F.S.4
-
2
-
-
33749378583
-
Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal dis
-
DOI 10.1242/dev.02513
-
Bangi, E. and Wharton, K. (2006). Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc. Development 133, 3295-3303. (Pubitemid 44501832)
-
(2006)
Development
, vol.133
, Issue.17
, pp. 3295-3303
-
-
Bangi, E.1
Wharton, K.2
-
3
-
-
37249016863
-
Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP)
-
DOI 10.1359/jbmr.071030
-
Billings, P. C., Fiori, J. L., Bentwood, J. L., O'Connell, M. P., Jiao, X., Nussbaum, B., Caron, R. J., Shore, E. M. and Kaplan, F. S. (2008). Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP). J. Bone Miner. Res. 23, 305-313. (Pubitemid 351304661)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.3
, pp. 305-313
-
-
Billings, P.C.1
Fiori, J.L.2
Bentwood, J.L.3
O'Connell, M.P.4
Jiao, X.5
Nussbaum, B.6
Caron, R.J.7
Shore, E.M.8
Kaplan, F.S.9
-
4
-
-
60749137428
-
Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: Confirmations and advancements
-
Bocciardi, R., Bordo, D., Di Duca, M., Di Rocco, M. and Ravazzolo, R. (2009). Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: confirmations and advancements. Eur. J. Hum. Genet. 17, 311-318.
-
(2009)
Eur. J. Hum. Genet.
, vol.17
, pp. 311-318
-
-
Bocciardi, R.1
Bordo, D.2
Di Duca, M.3
Di Rocco, M.4
Ravazzolo, R.5
-
5
-
-
73949145108
-
Mutational screening of ACVR1 gene in Brazilian fibrodysplasia ossificans progressiva patients
-
Carvalho, D. R., Navarro, M. M. M., Martins, B. J., Coelho, K. E., Mello, W. D., Takata, R. I. and Speck-Martins, C. E. (2010). Mutational screening of ACVR1 gene in Brazilian fibrodysplasia ossificans progressiva patients. Clin. Genet. 77, 171-176.
-
(2010)
Clin. Genet.
, vol.77
, pp. 171-176
-
-
Carvalho, D.R.1
Navarro, M.M.M.2
Martins, B.J.3
Coelho, K.E.4
Mello, W.D.5
Takata, R.I.6
Speck-Martins, C.E.7
-
6
-
-
84864115359
-
An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva
-
Chakkalakal, S. A., Zhang, D., Culbert, A. L., Convente, M. R., Caron, R. J., Wright, A. C., Maidment, A. D. A., Kaplan, F. S. and Shore, E. M. (2012). An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva. J. Bone Miner. Res. 27, 1746-1756.
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 1746-1756
-
-
Chakkalakal, S.A.1
Zhang, D.2
Culbert, A.L.3
Convente, M.R.4
Caron, R.J.5
Wright, A.C.6
Maidment, A.D.A.7
Kaplan, F.S.8
Shore, E.M.9
-
7
-
-
0027403045
-
The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients
-
Cohen, R. B., Hahn, G. V., Tabas, J. A., Peeper, J., Levitz, C. L., Sando, A., Sando, N., Zasloff, M. and Kaplan, F. S. (1993). The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients. J. Bone Joint Surg. Am. 75, 215-219. (Pubitemid 23093971)
-
(1993)
Journal of Bone and Joint Surgery - Series A
, vol.75
, Issue.2
, pp. 215-219
-
-
Cohen, R.B.1
Hahn, G.V.2
Tabas, J.A.3
Peeper, J.4
Levitz, C.L.5
Sando, A.6
Sando, N.7
Zasloff, M.8
Kaplan, F.S.9
-
8
-
-
0019945249
-
Fibrodysplasia ossificans progressiva. The clinical features and natural history of 34 patients
-
Connor, J. M. and Evans, D. A. (1982). Fibrodysplasia ossificans progressiva. The clinical features and natural history of 34 patients. J. Bone Joint Surg. Br. 64, 76-83. (Pubitemid 12005874)
-
(1982)
Journal of Bone and Joint Surgery - Series B
, vol.64
, Issue.1
, pp. 76-83
-
-
Connor, J.M.1
Evans, D.A.P.2
-
9
-
-
38949093587
-
Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva
-
DOI 10.2106/JBJS.G.00774
-
Deirmengian, G. K., Hebela, N. M., O'Connell, M., Glaser, D. L., Shore, E. M. and Kaplan, F. S. (2008). Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva. J. Bone Joint Surg. Am. 90, 366-374. (Pubitemid 351341049)
-
(2008)
Journal of Bone and Joint Surgery - Series A
, vol.90
, Issue.2
, pp. 366-374
-
-
Deirmengian, G.K.1
Hebela, N.M.2
O'Connell, M.3
Glaser, D.L.4
Shore, E.M.5
Kaplan, F.S.6
-
10
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
DOI 10.1038/nature02006
-
Derynck, R. and Zhang, Y. E. (2003). Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425, 577-584. (Pubitemid 37280136)
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
11
-
-
0027988792
-
Traumatic fractures of heterotopic bone in patients who have fibrodysplasia ossificans progressiva: A report of 2 cases
-
Einhorn, T. A. and Kaplan, F. S. (1994). Traumatic fractures of heterotopic bone in patients who have fibrodysplasia ossificans progressiva. A report of 2 cases. Clin. Orthop. Relat. Res. 308, 173-177. (Pubitemid 24349324)
-
(1994)
Clinical Orthopaedics and Related Research
, Issue.308
, pp. 173-177
-
-
Einhorn, T.A.1
Kaplan, F.S.2
-
12
-
-
33646865518
-
Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP)
-
DOI 10.1359/jbmr.060215
-
Fiori, J. L., Billings, P. C., de la Peña, L. S., Kaplan, F. S. and Shore, E. M. (2006). Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP). J. Bone Miner. Res. 21, 902-909. (Pubitemid 43787997)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.6
, pp. 902-909
-
-
Fiori, J.L.1
Billings, P.C.2
Serrano, D.L.P.L.3
Kaplan, F.S.4
Shore, E.M.5
-
13
-
-
70350044926
-
Heterotopic ossification in high-energy wartime extremity injuries: Prevalence and risk factors
-
Forsberg, J. A., Pepek, J. M., Wagner, S., Wilson, K., Flint, J., Andersen, R. C., Tadaki, D., Gage, F. A., Stojadinovic, A. and Elster, E. A. (2009). Heterotopic ossification in high-energy wartime extremity injuries: prevalence and risk factors. J. Bone Joint Surg. Am. 91, 1084-1091.
-
(2009)
J. Bone Joint Surg. Am.
, vol.91
, pp. 1084-1091
-
-
Forsberg, J.A.1
Pepek, J.M.2
Wagner, S.3
Wilson, K.4
Flint, J.5
Andersen, R.C.6
Tadaki, D.7
Gage, F.A.8
Stojadinovic, A.9
Elster, E.A.10
-
14
-
-
33646560934
-
Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2
-
DOI 10.1002/dvg.20201
-
Fukuda, T., Scott, G., Komatsu, Y., Araya, R., Kawano, M., Ray, M. K., Yamada, M. and Mishina, Y. (2006). Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2. Genesis 44, 159-167. (Pubitemid 43727738)
-
(2006)
Genesis
, vol.44
, Issue.4
, pp. 159-167
-
-
Fukuda, T.1
Scott, G.2
Komatsu, Y.3
Araya, R.4
Kawano, M.5
Ray, M.K.6
Yamada, M.7
Mishina, Y.8
-
15
-
-
56049098488
-
A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor
-
Fukuda, T., Kanomata, K., Nojima, J., Kokabu, S., Akita, M., Ikebuchi, K., Jimi, E., Komori, T., Maruki, Y., Matsuoka, M. et al. (2008). A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor. Biochem. Biophys. Res. Commun. 377, 905-909.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 905-909
-
-
Fukuda, T.1
Kanomata, K.2
Nojima, J.3
Kokabu, S.4
Akita, M.5
Ikebuchi, K.6
Jimi, E.7
Komori, T.8
Maruki, Y.9
Matsuoka, M.10
-
16
-
-
65449139561
-
Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva
-
Fukuda, T., Kohda, M., Kanomata, K., Nojima, J., Nakamura, A., Kamizono, J., Noguchi, Y., Iwakiri, K., Kondo, T., Kurose, J. et al. (2009). Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. J. Biol. Chem. 284, 7149-7156.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7149-7156
-
-
Fukuda, T.1
Kohda, M.2
Kanomata, K.3
Nojima, J.4
Nakamura, A.5
Kamizono, J.6
Noguchi, Y.7
Iwakiri, K.8
Kondo, T.9
Kurose, J.10
-
17
-
-
38849093307
-
A unique case of fihrodysplasia ossificans progressiva with an ACVR1 mutation, G356D, other than the common mutation (R206H)
-
DOI 10.1002/ajmg.a.32151
-
Furuya, H., Ikezoe, K., Wang, L. X., Ohyagi, Y., Motomura, K., Fujii, N., Kira, J. and Fukumaki, Y. (2008). A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, G356D, other than the common mutation (R206H). Am. J. Med. Genet. 146A, 459-463. (Pubitemid 351206817)
-
(2008)
American Journal of Medical Genetics, Part A
, vol.146
, Issue.4
, pp. 459-463
-
-
Furuya, H.1
Ikezoe, K.2
Wang, L.3
Ohyagi, Y.4
Motomura, K.5
Fujii, N.6
Kira, J.-I.7
Fukumaki, Y.8
-
18
-
-
0031059563
-
Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva
-
DOI 10.1016/S0046-8177(97)90133-7
-
Gannon, F. H., Kaplan, F. S., Olmsted, E., Finkel, G. C., Zasloff, M. A. and Shore, E. (1997). Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva. Hum. Pathol. 28, 339-343. (Pubitemid 27106087)
-
(1997)
Human Pathology
, vol.28
, Issue.3
, pp. 339-343
-
-
Gannon, F.H.1
Kaplan, F.S.2
Olmsted, E.3
Finkel, G.C.4
Zasloff, M.A.5
Shore, E.6
-
19
-
-
0031984796
-
Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva
-
Gannon, F. H., Valentine, B. A., Shore, E. M., Zasloff, M. A. and Kaplan, F. S. (1998). Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 346, 19-25. (Pubitemid 28046863)
-
(1998)
Clinical Orthopaedics and Related Research
, Issue.346
, pp. 19-25
-
-
Gannon, F.H.1
Valentine, B.A.2
Shore, E.M.3
Zasloff, M.A.4
Kaplan, F.S.5
-
20
-
-
0034878150
-
Mast cell involvement in fibrodysplasia ossificans progressiva
-
DOI 10.1053/hupa.2001.26464
-
Gannon, F. H., Glaser, D., Caron, R., Thompson, L. D., Shore, E. M. and Kaplan, F. S. (2001). Mast cell involvement in fibrodysplasia ossificans progressiva. Hum. Pathol. 32, 842-848. (Pubitemid 32803986)
-
(2001)
Human Pathology
, vol.32
, Issue.8
, pp. 842-848
-
-
Gannon, F.H.1
Glaser, D.2
Caron, R.3
Thompson, L.D.R.4
Shore, E.M.5
Kaplan, F.S.6
-
21
-
-
33846004405
-
Bone morphogenetic proteins and their antagonists
-
DOI 10.1007/s11154-006-9000-6, Special Issue on Osteoporosis
-
Gazzerro, E. and Canalis, E. (2006). Bone morphogenetic proteins and their antagonists. Rev. Endocr. Metab. Disord. 7, 51-65. (Pubitemid 46044349)
-
(2006)
Reviews in Endocrine and Metabolic Disorders
, vol.7
, Issue.1-2
, pp. 51-65
-
-
Gazzerro, E.1
Canalis, E.2
-
22
-
-
0031964498
-
Catastrophic falls in patients who have fibrodysplasia ossificans progressiva
-
Glaser, D. L., Rocke, D. M. and Kaplan, F. S. (1998). Catastrophic falls in patients who have fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 346, 110-116. (Pubitemid 28046874)
-
(1998)
Clinical Orthopaedics and Related Research
, Issue.346
, pp. 110-116
-
-
Glaser, D.L.1
Rocke, D.M.2
Kaplan, F.S.3
-
23
-
-
10744229194
-
4-Induced Heterotopic Ossification
-
Glaser, D. L., Economides, A. N., Wang, L., Liu, X., Kimble, R. D., Fandl, J. P., Wilson, J. M., Stahl, N., Kaplan, F. S. and Shore, E. M. (2003). In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. J. Bone Joint Surg. Am. 85, 2332-2342. (Pubitemid 37499642)
-
(2003)
Journal of Bone and Joint Surgery - Series A
, vol.85
, Issue.12
, pp. 2332-2342
-
-
Glaser, D.L.1
Economides, A.N.2
Wang, L.3
Liu, X.4
Kimble, R.D.5
Fandl, J.P.6
Wilson, J.M.7
Stahl, N.8
Kaplan, F.S.9
Shore, E.M.10
-
24
-
-
79751537956
-
A novel ACVR1 mutation in the glycine/serine-rich domain found in the most benign case of a fibrodysplasia ossificans progressiva variant reported to date
-
Gregson, C. L., Hollingworth, P., Williams, M., Petrie, K. A., Bullock, A. N., Brown, M. A., Tobias, J. H. and Triffitt, J. T. (2011). A novel ACVR1 mutation in the glycine/serine-rich domain found in the most benign case of a fibrodysplasia ossificans progressiva variant reported to date. Bone 48, 654-658.
-
(2011)
Bone
, vol.48
, pp. 654-658
-
-
Gregson, C.L.1
Hollingworth, P.2
Williams, M.3
Petrie, K.A.4
Bullock, A.N.5
Brown, M.A.6
Tobias, J.H.7
Triffitt, J.T.8
-
25
-
-
34548457296
-
Functional modeling of the ACVR1 (R206H) mutation in FOP
-
DOI 10.1097/BLO.0b013e318126c049, PII 0000308620070900000015
-
Groppe, J. C., Shore, E. M. and Kaplan, F. S. (2007). Functional modeling of the ACVR1 (R206H) mutation in FOP. Clin. Orthop. Relat. Res. 462, 87-92. (Pubitemid 47367848)
-
(2007)
Clinical Orthopaedics and Related Research
, Issue.462
, pp. 87-92
-
-
Groppe, J.C.1
Shore, E.M.2
Kaplan, F.S.3
-
26
-
-
80051799654
-
In vitro analyses of the dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP
-
Groppe, J. C., Wu, J., Shore, E. M. and Kaplan, F. S. (2011). In vitro analyses of the dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP. Cells Tissues Organs 194, 291-295.
-
(2011)
Cells Tissues Organs
, vol.194
, pp. 291-295
-
-
Groppe, J.C.1
Wu, J.2
Shore, E.M.3
Kaplan, F.S.4
-
27
-
-
0042025193
-
Osteoinduction by ex vivo adenovirus-mediated BMP2 delivery is independent of cell type
-
DOI 10.1038/sj.gt.3302006
-
Gugala, Z., Olmsted-Davis, E. A., Gannon, F. H., Lindsey, R. W. and Davis, A. R. (2003). Osteoinduction by ex vivo adenovirus-mediated BMP2 delivery is independent of cell type. Gene Ther. 10, 1289-1296. (Pubitemid 36987119)
-
(2003)
Gene Therapy
, vol.10
, Issue.16
, pp. 1289-1296
-
-
Gugala, Z.1
Olmsted-Davis, E.A.2
Gannon, F.H.3
Lindsey, R.W.4
Davis, A.R.5
-
28
-
-
25844516368
-
Three pairs of monozygotic twins with fibrodysplasia ossificans progressiva: The role of environment in the progression of heterotopic ossification
-
DOI 10.1385/BMM:3:3-4:205
-
Hebela, N., Shore, E. M. and Kaplan, F. S. (2005). Three pairs of monozygotic twins with fibrodysplasia ossificans progressiva: the role of environment in the progression of heterotopic ossification. CRBMM 3, 205-208. (Pubitemid 41400336)
-
(2005)
Clinical Reviews in Bone and Mineral Metabolism
, vol.3
, Issue.3-4
, pp. 205-208
-
-
Hebela, N.1
Shore, E.M.2
Kaplan, F.S.3
-
29
-
-
0141626663
-
Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: Clues to a vascular origin of heterotopic ossification?
-
DOI 10.1002/path.1413
-
Hegyi, L., Gannon, F. H., Glaser, D. L., Shore, E. M., Kaplan, F. S. and Shanahan, C. M. (2003). Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification? J. Pathol. 201, 141-148. (Pubitemid 37121213)
-
(2003)
Journal of Pathology
, vol.201
, Issue.1
, pp. 141-148
-
-
Hegyi, L.1
Gannon, F.H.2
Glaser, D.L.3
Shore, E.M.4
Kaplan, F.S.5
Shanahan, C.M.6
-
30
-
-
70849128432
-
Applications of small molecule BMP inhibitors in physiology and disease
-
Hong, C. C. and Yu, P. B. (2009). Applications of small molecule BMP inhibitors in physiology and disease. Cytokine Growth Factor Rev. 20, 409-418.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 409-418
-
-
Hong, C.C.1
Yu, P.B.2
-
31
-
-
0033524943
-
Crystal structure of the cytoplasmic domain of the type I TGFβ receptor in complex with FKBP12
-
DOI 10.1016/S0092-8674(00)80555-3
-
Huse, M., Chen, Y. G., Massagué, J. and Kuriyan, J. (1999). Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell 96, 425-436. (Pubitemid 29077596)
-
(1999)
Cell
, vol.96
, Issue.3
, pp. 425-436
-
-
Huse, M.1
Chen, Y.-G.2
Massague, J.3
Kuriyan, J.4
-
32
-
-
0034796457
-
The TGFβ receptor activation process: An inhibitor- to substrate-binding switch
-
DOI 10.1016/S1097-2765(01)00332-X
-
Huse, M., Muir, T. W., Xu, L., Chen, Y. G., Kuriyan, J. and Massagué, J. (2001). The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Mol. Cell 8, 671-682. (Pubitemid 32946943)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 671-682
-
-
Huse, M.1
Muir, T.W.2
Xu, L.3
Chen, Y.-G.4
Kuriyan, J.5
Massague, J.6
-
33
-
-
0030022304
-
Fibrodysplasia ossificans progressiva in two half-sisters: Evidence for maternal mosaicism
-
Janoff, H. B., Muenke, M., Johnson, L. O., Rosenberg, A., Shore, E. M., Okereke, E., Zasloff, M. and Kaplan, F. S. (1996). Fibrodysplasia ossificans progressiva in two half-sisters: evidence for maternal mosaicism. Am. J. Med. Genet. 61, 320-324.
-
(1996)
Am. J. Med. Genet.
, vol.61
, pp. 320-324
-
-
Janoff, H.B.1
Muenke, M.2
Johnson, L.O.3
Rosenberg, A.4
Shore, E.M.5
Okereke, E.6
Zasloff, M.7
Kaplan, F.S.8
-
34
-
-
4644264945
-
Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype
-
Kan, L., Hu, M., Gomes, W. A. and Kessler, J. A. (2004). Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype. Am. J. Pathol. 165, 1107-1115. (Pubitemid 39297718)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.4
, pp. 1107-1115
-
-
Kan, L.1
Hu, M.2
Gomes, W.A.3
Kessler, J.A.4
-
35
-
-
59849119987
-
Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification
-
Kan, L., Liu, Y., McGuire, T. L., Berger, D. M., Awatramani, R. B., Dymecki, S. M. and Kessler, J. A. (2009). Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification. Stem Cells 27, 150-156.
-
(2009)
Stem Cells
, vol.27
, pp. 150-156
-
-
Kan, L.1
Liu, Y.2
McGuire, T.L.3
Berger, D.M.4
Awatramani, R.B.5
Dymecki, S.M.6
Kessler, J.A.7
-
36
-
-
80053028119
-
Substance P signaling mediates BMP-dependent heterotopic ossification
-
Kan, L., Lounev, V. Y., Pignolo, R. J., Duan, L., Liu, Y., Stock, S. R., McGuire, T. L., Lu, B., Gerard, N. P., Shore, E. M. et al. (2011). Substance P signaling mediates BMP-dependent heterotopic ossification. J. Cell. Biochem. 112, 2759-2772.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 2759-2772
-
-
Kan, L.1
Lounev, V.Y.2
Pignolo, R.J.3
Duan, L.4
Liu, Y.5
Stock, S.R.6
McGuire, T.L.7
Lu, B.8
Gerard, N.P.9
Shore, E.M.10
-
37
-
-
25844510176
-
Thoracic insufficiency syndrome in patients with fibrodysplasia ossificans progressiva
-
DOI 10.1385/BMM:3:3-4:213
-
Kaplan, F. S. and Glaser, D. L. (2005). Thoracic insufficiency syndrome in patients with fibrodysplasia ossificans progressiva. CRBMM 3, 213-216. (Pubitemid 41400338)
-
(2005)
Clinical Reviews in Bone and Mineral Metabolism
, vol.3
, Issue.3-4
, pp. 213-216
-
-
Kaplan, F.S.1
Glaser, D.L.2
-
38
-
-
79953730788
-
Derailing heterotopic ossification and RARing to go
-
Kaplan, F. S. and Shore, E. M. (2011). Derailing heterotopic ossification and RARing to go. Nat. Med. 17, 420-421.
-
(2011)
Nat. Med.
, vol.17
, pp. 420-421
-
-
Kaplan, F.S.1
Shore, E.M.2
-
39
-
-
0025307333
-
Fibrodysplasia ossificans progressiva: A clue from the fly?
-
DOI 10.1007/BF02555995
-
Kaplan, F. S., Tabas, J. A. and Zasloff, M. A. (1990). Fibrodysplasia ossificans progressiva: a clue from the fly? Calcif. Tissue Int. 47, 117-125. (Pubitemid 20238176)
-
(1990)
Calcified Tissue International
, vol.47
, Issue.2
, pp. 117-125
-
-
Kaplan, F.S.1
Tabas, J.A.2
Zasloff, M.A.3
-
40
-
-
0027477670
-
The histopathology of fibrodysplasia ossificans progressiva. An endochondral process
-
Kaplan, F. S., Tabas, J. A., Gannon, F. H., Finkel, G., Hahn, G. V. and Zasloff, M. A. (1993a). The histopathology of fibrodysplasia ossificans progressiva. An endochondral process. J. Bone Joint Surg. Am. 75, 220-230. (Pubitemid 23093972)
-
(1993)
Journal of Bone and Joint Surgery - Series A
, vol.75
, Issue.2
, pp. 220-230
-
-
Kaplan, F.S.1
Tabas, J.A.2
Gannon, F.H.3
Finkel, G.4
Hahn, G.V.5
Zasloff, M.A.6
-
41
-
-
0027260694
-
Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family
-
Kaplan, F. S., McCluskey, W., Hahn, G., Tabas, J. A., Muenke, M. and Zasloff, M. A. (1993b). Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family. J. Bone Joint Surg. Am. 75, 1214-1220. (Pubitemid 23267913)
-
(1993)
Journal of Bone and Joint Surgery - Series A
, vol.75
, Issue.8
, pp. 1214-1220
-
-
Kaplan, F.S.1
McCluskey, W.2
Hahn, G.3
Tabas, J.A.4
Muenke, M.5
Zasloff, M.A.6
-
42
-
-
0027929950
-
Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva
-
Kaplan, F. S., Strear, C. M. and Zasloff, M. A. (1994). Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 304, 238-247. (Pubitemid 24230691)
-
(1994)
Clinical Orthopaedics and Related Research
, Issue.304
, pp. 238-247
-
-
Kaplan, F.S.1
Strear, C.M.2
Zasloff, M.A.3
-
43
-
-
0031984797
-
Urinary basic fibroblast growth factor: A biochemical marker for preosseous fibroproliferative lesions in patients with fibrodysplasia ossificans progressiva
-
Kaplan, F., Sawyer, J., Connors, S., Keough, K., Shore, E., Gannon, F., Glaser, D., Rocke, D., Zasloff, M. and Folkman, J. (1998). Urinary basic fibroblast growth factor. A biochemical marker for preosseous fibroproliferative lesions in patients with fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 346, 59-65. (Pubitemid 28046868)
-
(1998)
Clinical Orthopaedics and Related Research
, Issue.346
, pp. 59-65
-
-
Kaplan, F.1
Sawyer, J.2
Connors, S.3
Keough, K.4
Shore, E.5
Gannon, F.6
Glaser, D.7
Rocke, D.8
Zasloff, M.9
Folkman, J.10
-
44
-
-
3042701421
-
Heterotopic ossification
-
Kaplan, F. S., Glaser, D. L., Hebela, N. and Shore, E. M. (2004). Heterotopic ossification. J. Am. Acad. Orthop. Surg. 12, 116-125.
-
(2004)
J. Am. Acad. Orthop. Surg.
, vol.12
, pp. 116-125
-
-
Kaplan, F.S.1
Glaser, D.L.2
Hebela, N.3
Shore, E.M.4
-
45
-
-
25844469044
-
Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway
-
Kaplan, F. S., Shore, E. M., Gupta, R., Billings, P. C., Glaser, D. L., Pignolo, R. J., Graf, D. and Kamoun, M. (2005a). Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway. CRBMM 3, 189-194.
-
(2005)
CRBMM
, vol.3
, pp. 189-194
-
-
Kaplan, F.S.1
Shore, E.M.2
Gupta, R.3
Billings, P.C.4
Glaser, D.L.5
Pignolo, R.J.6
Graf, D.7
Kamoun, M.8
-
46
-
-
25844487690
-
The phenotype of fibrodysplasia ossificans progressiva
-
DOI 10.1385/BMM:3:3-4:183
-
Kaplan, F. S., Glaser, D. L., Shore, E. M., Deirmengian, G. K., Gupta, R., Delai, P., Morhart, R., Smith, R., Le Merrer, M., Rogers, J. G. et al. (2005b). The phenotype of fibrodysplasia ossificans progressiva. CRBMM 3, 183-188. (Pubitemid 41400332)
-
(2005)
Clinical Reviews in Bone and Mineral Metabolism
, vol.3
, Issue.3-4
, pp. 183-188
-
-
Kaplan, F.S.1
Glaser, D.L.2
Shore, E.M.3
Deirmengian, G.K.4
Gupta, R.5
Delai, P.6
Morhart, R.7
Smith, R.8
Le, M.M.9
Rogers, J.G.10
Connor, J.M.11
Kitterman, J.A.12
-
47
-
-
33846839273
-
Hematopoietic stem-cell contribution to ectopic skeletogenesis
-
DOI 10.2106/JBJS.F.00472
-
Kaplan, F. S., Glaser, D. L., Shore, E. M., Pignolo, R. J., Xu, M., Zhang, Y., Senitzer, D., Forman, S. J. and Emerson, S. G. (2007a). Hematopoietic stem-cell contribution to ectopic skeletogenesis. J. Bone Joint Surg. Am. 89, 347-357. (Pubitemid 46214354)
-
(2007)
Journal of Bone and Joint Surgery - Series A
, vol.89
, Issue.2
, pp. 347-357
-
-
Kaplan, F.S.1
Glaser, D.L.2
Shore, E.M.3
Pignolo, R.J.4
Xu, M.5
Zhang, Y.6
Senitzer, D.7
Forman, S.J.8
Emerson, S.G.9
-
48
-
-
34248223174
-
A new era for fibrodysplasia ossificans progressiva: A druggable target for the second skeleton
-
DOI 10.1517/14712598.7.5.705
-
Kaplan, F. S., Glaser, D. L., Pignolo, R. J. and Shore, E. M. (2007b). A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton. Expert Opin. Biol. Ther. 7, 705-712. (Pubitemid 46710933)
-
(2007)
Expert Opinion on Biological Therapy
, vol.7
, Issue.5
, pp. 705-712
-
-
Kaplan, F.S.1
Glaser, D.L.2
Pignolo, R.J.3
Shore, E.M.4
-
49
-
-
40149099148
-
Fibrodysplasia ossificans progressiva
-
DOI 10.1016/j.berh.2007.11.007, PII S1521694207001313
-
Kaplan, F. S., Le Merrer, M., Glaser, D. L., Pignolo, R. J., Goldsby, R. E., Kitterman, J. A., Groppe, J. and Shore, E. M. (2008a). Fibrodysplasia ossificans progressiva. Best Pract. Res. Clin. Rheumatol. 22, 191-205. (Pubitemid 351325734)
-
(2008)
Best Practice and Research: Clinical Rheumatology
, vol.22
, Issue.1
, pp. 191-205
-
-
Kaplan, F.S.1
Le, M.M.2
Glaser, D.L.3
Pignolo, R.J.4
Goldsby, R.E.5
Kitterman, J.A.6
Groppe, J.7
Shore, E.M.8
-
50
-
-
44449166223
-
Early diagnosis of fibrodysplasia ossificans progressiva
-
Kaplan, F. S., Xu, M., Glaser, D. L., Collins, F., Connor, M., Kitterman, J., Sillence, D., Zackai, E., Ravitsky, V., Zasloff, M. et al. (2008b). Early diagnosis of fibrodysplasia ossificans progressiva. Pediatrics 121, e1295-e1300.
-
(2008)
Pediatrics
, vol.121
-
-
Kaplan, F.S.1
Xu, M.2
Glaser, D.L.3
Collins, F.4
Connor, M.5
Kitterman, J.6
Sillence, D.7
Zackai, E.8
Ravitsky, V.9
Zasloff, M.10
-
51
-
-
61649084689
-
Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1
-
Kaplan, F. S., Xu, M., Seemann, P., Connor, J. M., Glaser, D. L., Carroll, L., Delai, P., Fastnacht-Urban, E., Forman, S. J., Gillessen-Kaesbach, G. et al. (2009a). Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. Hum. Mutat. 30, 379-390.
-
(2009)
Hum. Mutat.
, vol.30
, pp. 379-390
-
-
Kaplan, F.S.1
Xu, M.2
Seemann, P.3
Connor, J.M.4
Glaser, D.L.5
Carroll, L.6
Delai, P.7
Fastnacht-Urban, E.8
Forman, S.J.9
Gillessen-Kaesbach, G.10
-
52
-
-
70649090107
-
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling
-
Kaplan, F. S., Pignolo, R. J. and Shore, E. M. (2009b). The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling. Cytokine Growth Factor Rev. 20, 399-407.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 399-407
-
-
Kaplan, F.S.1
Pignolo, R.J.2
Shore, E.M.3
-
53
-
-
77950874805
-
Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva
-
Kaplan, F. S., Zasloff, M. A., Kitterman, J. A., Shore, E. M., Hong, C. C. and Rocke, D. M. (2010a). Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva. J. Bone Joint Surg. Am. 92, 686-691.
-
(2010)
J. Bone Joint Surg. Am.
, vol.92
, pp. 686-691
-
-
Kaplan, F.S.1
Zasloff, M.A.2
Kitterman, J.A.3
Shore, E.M.4
Hong, C.C.5
Rocke, D.M.6
-
54
-
-
79957448134
-
Fibrodysplasia ossificans progressiva: Developmental implications of a novel metamorphogene
-
(ed. F. Bronner, M. C. Farach-Carson and H. I. Roach). London, UK: Springer-Verlag
-
Kaplan, F. S., Groppe, J. C., Seemann, P., Pignolo, R. J. and Shore, E. M. (2010b). Fibrodysplasia ossificans progressiva: developmental implications of a novel metamorphogene. In Bone and Development (ed. F. Bronner, M. C. Farach-Carson and H. I. Roach). London, UK: Springer-Verlag.
-
(2010)
Bone and Development
-
-
Kaplan, F.S.1
Groppe, J.C.2
Seemann, P.3
Pignolo, R.J.4
Shore, E.M.5
-
55
-
-
81255197446
-
Fibrodysplasia ossificans progressiva: A blueprint for metamorphosis
-
Kaplan, F. S., Lounev, V. Y., Wang, H., Pignolo, R. J. and Shore, E. M. (2011). Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis. Ann. N. Y. Acad. Sci. 1237, 5-10.
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1237
, pp. 5-10
-
-
Kaplan, F.S.1
Lounev, V.Y.2
Wang, H.3
Pignolo, R.J.4
Shore, E.M.5
-
56
-
-
84863723222
-
Restoration of normal BMP signaling levels and osteogenic differentiation in FOP mesenchymal progenitor cells by mutant allele-specific targeting
-
Kaplan, J., Kaplan, F. S. and Shore, E. M. (2012). Restoration of normal BMP signaling levels and osteogenic differentiation in FOP mesenchymal progenitor cells by mutant allele-specific targeting. Gene Ther. 19, 786-790.
-
(2012)
Gene Ther.
, vol.19
, pp. 786-790
-
-
Kaplan, J.1
Kaplan, F.S.2
Shore, E.M.3
-
57
-
-
25844523629
-
Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva
-
DOI 10.1542/peds.2005-0469
-
Kitterman, J. A., Kantanie, S., Rocke, D. M. and Kaplan, F. S. (2005). Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva. Pediatrics 116, e654-e661. (Pubitemid 46056396)
-
(2005)
Pediatrics
, vol.116
, Issue.5
-
-
Kitterman, J.A.1
Kantanie, S.2
Rocke, D.M.3
Kaplan, F.S.4
-
58
-
-
0031974285
-
Pulmonary and cardiac function in advanced fibrodysplasia ossificans progressiva
-
Kussmaul, W. G., Esmail, A. N., Sagar, Y., Ross, J., Gregory, S. and Kaplan, F. S. (1998). Pulmonary and cardiac function in advanced fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 346, 104-109. (Pubitemid 28046873)
-
(1998)
Clinical Orthopaedics and Related Research
, Issue.346
, pp. 104-109
-
-
Kussmaul, W.G.1
Esmail, A.N.2
Sagar, Y.3
Ross, J.4
Gregory, S.5
Kaplan, F.S.6
-
59
-
-
0029012733
-
Permanent heterotopic ossification at the injection site after diphtheria-tetanuspertussis immunizations in children who have fibrodysplasia ossificans progressiva
-
Lanchoney, T. F., Cohen, R. B., Rocke, D. M., Zasloff, M. A. and Kaplan, F. S. (1995). Permanent heterotopic ossification at the injection site after diphtheria-tetanuspertussis immunizations in children who have fibrodysplasia ossificans progressiva. J. Pediatr. 126, 762-764.
-
(1995)
J. Pediatr.
, vol.126
, pp. 762-764
-
-
Lanchoney, T.F.1
Cohen, R.B.2
Rocke, D.M.3
Zasloff, M.A.4
Kaplan, F.S.5
-
60
-
-
83655203094
-
Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva
-
Le, V. Q. and Wharton, K. A. (2012). Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva. Dev. Dyn. 241, 200-214.
-
(2012)
Dev. Dyn.
, vol.241
, pp. 200-214
-
-
Le, V.Q.1
Wharton, K.A.2
-
61
-
-
0033142884
-
Conductive hearing loss in individuals with fibrodysplasia ossificans progressiva
-
Levy, C. E., Lash, A. T., Janoff, H. B. and Kaplan, F. S. (1999). Conductive hearing loss in individuals with fibrodysplasia ossificans progressiva. Am. J. Audiol. 8, 29-33.
-
(1999)
Am. J. Audiol.
, vol.8
, pp. 29-33
-
-
Levy, C.E.1
Lash, A.T.2
Janoff, H.B.3
Kaplan, F.S.4
-
62
-
-
67349187409
-
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
-
Little, S. C. and Mullins, M. C. (2009). Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat. Cell Biol. 11, 637-643.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 637-643
-
-
Little, S.C.1
Mullins, M.C.2
-
63
-
-
62549145351
-
Identification of progenitor cells that contribute to heterotopic skeletogenesis
-
Lounev, V. Y., Ramachandran, R., Wosczyna, M. N., Yamamoto, M., Maidment, A. D., Shore, E. M., Glaser, D. L., Goldhamer, D. J. and Kaplan, F. S. (2009). Identification of progenitor cells that contribute to heterotopic skeletogenesis. J. Bone Joint Surg. Am. 91, 652-663.
-
(2009)
J. Bone Joint Surg. Am.
, vol.91
, pp. 652-663
-
-
Lounev, V.Y.1
Ramachandran, R.2
Wosczyna, M.N.3
Yamamoto, M.4
Maidment, A.D.5
Shore, E.M.6
Glaser, D.L.7
Goldhamer, D.J.8
Kaplan, F.S.9
-
64
-
-
0029678648
-
Severe restriction in jaw movement after routine injection of local anesthetic in patients who have Fibrodysplasia Ossificans Progressiva
-
Luchetti, W., Cohen, R. B., Hahn, G. V., Rocke, D. M., Helpin, M., Zasloff, M. and Kaplan, F. S. (1996). Severe restriction in jaw movement after routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 81, 21-25. (Pubitemid 126812873)
-
(1996)
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
, vol.81
, Issue.1
, pp. 21-25
-
-
Luchetti, W.1
Cohen, R.B.2
Hahn, G.V.3
Rocke, D.M.4
Helpin, M.5
Zasloff, M.6
Kaplan, F.S.7
-
65
-
-
0001495174
-
Myositis ossificans progressiva: Mineral, metabolic, and radioactive calcium studies of the effects of hormones
-
Lutwak, L. (1964). Myositis ossificans progressiva: mineral, metabolic, and radioactive calcium studies of the effects of hormones. Am. J. Med. 37, 269-293.
-
(1964)
Am. J. Med.
, vol.37
, pp. 269-293
-
-
Lutwak, L.1
-
66
-
-
25844522195
-
A few hundred people turned to bone
-
Maeder, T. (1998). A few hundred people turned to bone. The Atlantic Monthly 281, 81-89.
-
(1998)
The Atlantic Monthly
, vol.281
, pp. 81-89
-
-
Maeder, T.1
-
67
-
-
0035020150
-
Fibrodysplasia ossificans progressiva
-
DOI 10.1007/s002470100447
-
Mahboubi, S., Glaser, D. L., Shore, E. M. and Kaplan, F. S. (2001). Fibrodysplasia ossificans progressiva. Pediatr. Radiol. 31, 307-314. (Pubitemid 32422034)
-
(2001)
Pediatric Radiology
, vol.31
, Issue.5
, pp. 307-314
-
-
Mahboubi, S.1
Glaser, D.L.2
Shore, E.M.3
Kaplan, F.S.4
-
68
-
-
78650018824
-
Conversion of vascular endothelial cells into multipotent stem-like cells
-
Medici, D., Shore, E. M., Lounev, V. Y., Kaplan, F. S., Kalluri, R. and Olsen, B. R. (2010). Conversion of vascular endothelial cells into multipotent stem-like cells. Nat. Med. 16, 1400-1406.
-
(2010)
Nat. Med.
, vol.16
, pp. 1400-1406
-
-
Medici, D.1
Shore, E.M.2
Lounev, V.Y.3
Kaplan, F.S.4
Kalluri, R.5
Olsen, B.R.6
-
69
-
-
0035916929
-
Bone formation and inflammation in cardiac valves
-
Mohler, E. R., 3rd, Gannon, F., Reynolds, C., Zimmerman, R., Keane, M. G. and Kaplan, F. S. (2001). Bone formation and inflammation in cardiac valves. Circulation 103, 1522-1528. (Pubitemid 32226259)
-
(2001)
Circulation
, vol.103
, Issue.11
, pp. 1522-1528
-
-
Mohler III, E.R.1
Gannon, F.2
Reynolds, C.3
Zimmerman, R.4
Keane, M.G.5
Kaplan, F.S.6
-
70
-
-
67649889413
-
Chin-on-chest deformity in patients with fibrodysplasia ossificans progressiva. A case series
-
Moore, R. E., Dormans, J. P., Drummond, D. S., Shore, E. M., Kaplan, F. S. and Auerbach, J. D. (2009). Chin-on-chest deformity in patients with fibrodysplasia ossificans progressiva. A case series. J. Bone Joint Surg. Am. 91, 1497-1502.
-
(2009)
J. Bone Joint Surg. Am.
, vol.91
, pp. 1497-1502
-
-
Moore, R.E.1
Dormans, J.P.2
Drummond, D.S.3
Shore, E.M.4
Kaplan, F.S.5
Auerbach, J.D.6
-
71
-
-
0036435027
-
Incidence of heterotopic bone formation after major hip surgery
-
DOI 10.1046/j.1445-2197.2002.02549.x
-
Neal, B., Gray, H., MacMahon, S. and Dunn, L. (2002). Incidence of heterotopic bone formation after major hip surgery. ANZ J. Surg. 72, 808-821. (Pubitemid 35370622)
-
(2002)
ANZ Journal of Surgery
, vol.72
, Issue.11
, pp. 808-821
-
-
Neal, B.1
Gray, H.2
MacMahon, S.3
Dunn, L.4
-
72
-
-
63749106137
-
Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients
-
Petrie, K. A., Lee, W. H., Bullock, A. N., Pointon, J. J., Smith, R., Russell, R. G., Brown, M. A., Wordsworth, B. P. and Triffitt, J. T. (2009). Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients. PLoS ONE 4, e5005.
-
(2009)
PLoS ONE
, vol.4
-
-
Petrie, K.A.1
Lee, W.H.2
Bullock, A.N.3
Pointon, J.J.4
Smith, R.5
Russell, R.G.6
Brown, M.A.7
Wordsworth, B.P.8
Triffitt, J.T.9
-
73
-
-
25844492010
-
Nonhereditary heterotopic ossification
-
Pignolo, R. J. and Foley, K. L. (2005). Nonhereditary heterotopic ossification. CRBMM 3, 261-266.
-
(2005)
CRBMM
, vol.3
, pp. 261-266
-
-
Pignolo, R.J.1
Foley, K.L.2
-
74
-
-
25844456883
-
The fibrodysplasia ossificans progressiva lesion
-
DOI 10.1385/BMM:3:3-4:195
-
Pignolo, R. J., Suda, R. K. and Kaplan, F. S. (2005). The fibrodysplasia ossificans progressiva lesion. CRBMM 3, 195-200. (Pubitemid 41400334)
-
(2005)
Clinical Reviews in Bone and Mineral Metabolism
, vol.3
, Issue.3-4
, pp. 195-200
-
-
Pignolo, R.J.1
Suda, R.K.2
Kaplan, F.S.3
-
75
-
-
33847644415
-
Heterotopic ossification in the residual limbs of traumatic and combat-related amputees
-
Potter, B. K., Burns, T. C., Lacap, A. P., Granville, R. R. and Gajewski, D. (2006). Heterotopic ossification in the residual limbs of traumatic and combat-related amputees. J. Am. Acad. Orthop. Surg. 14, S191-S197.
-
(2006)
J. Am. Acad. Orthop. Surg.
, vol.14
-
-
Potter, B.K.1
Burns, T.C.2
Lacap, A.P.3
Granville, R.R.4
Gajewski, D.5
-
76
-
-
72949121253
-
Rarely occurring mutation of ACVR1 gene in Moroccan patient with fibrodysplasia ossificans progressiva
-
Ratbi, I., Borcciadi, R., Regragui, A., Ravazzolo, R. and Sefiani, A. (2010). Rarely occurring mutation of ACVR1 gene in Moroccan patient with fibrodysplasia ossificans progressiva. Clin. Rheumatol. 29, 119-121.
-
(2010)
Clin. Rheumatol.
, vol.29
, pp. 119-121
-
-
Ratbi, I.1
Borcciadi, R.2
Regragui, A.3
Ravazzolo, R.4
Sefiani, A.5
-
77
-
-
0028287031
-
Age- and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva
-
Rocke, D. M., Zasloff, M., Peeper, J., Cohen, R. B. and Kaplan, F. S. (1994). Age- and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 301, 243-248. (Pubitemid 24119281)
-
(1994)
Clinical Orthopaedics and Related Research
, Issue.301
, pp. 243-248
-
-
Rocke, D.M.1
Zasloff, M.2
Peeper, J.3
Cohen, R.B.4
Kaplan, F.S.5
-
78
-
-
0018418612
-
Paternal age effect in fibrodysplasia ossificans progressiva
-
Rogers, J. G. and Chase, G. A. (1979). Paternal age effect in fibrodysplasia ossificans progressiva. J. Med. Genet. 16, 147-148. (Pubitemid 9164910)
-
(1979)
Journal of Medical Genetics
, vol.16
, Issue.2
, pp. 147-148
-
-
Rogers, J.G.1
Chase, G.A.2
-
79
-
-
80053034418
-
Sensory nerve induced inflammation contributes to heterotopic ossification
-
Salisbury, E., Rodenberg, E., Sonnet, C., Hipp, J., Gannon, F. H., Vadakkan, T. J., Dickinson, M. E., Olmsted-Davis, E. A. and Davis, A. R. (2011). Sensory nerve induced inflammation contributes to heterotopic ossification. J. Cell. Biochem. 112, 2748-2758.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 2748-2758
-
-
Salisbury, E.1
Rodenberg, E.2
Sonnet, C.3
Hipp, J.4
Gannon, F.H.5
Vadakkan, T.J.6
Dickinson, M.E.7
Olmsted-Davis, E.A.8
Davis, A.R.9
-
80
-
-
2942750256
-
Influenza-like viral illnesses and flare-ups of fibrodysplasia ossificans progressiva
-
Scarlett, R. F., Rocke, D. M., Kantanie, S., Patel, J. B., Shore, E. M. and Kaplan, F. S. (2004). Influenza-like viral illnesses and flare-ups of fibrodysplasia ossificans progressiva. Clin. Orthop. Relat. Res. 423, 275-279. (Pubitemid 38787751)
-
(2004)
Clinical Orthopaedics and Related Research
, Issue.423
, pp. 275-279
-
-
Scarlett, R.F.1
Rocke, D.M.2
Kantanie, S.3
Patel, J.B.4
Shore, E.M.5
Kaplan, F.S.6
-
81
-
-
25844529319
-
Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: Clues from the BMP signaling pathway
-
DOI 10.1097/01.brs.0000166619.22832.2c
-
Schaffer, A. A., Kaplan, F. S., Tracy, M. R., O'Brien, M. L., Dormans, J. P., Shore, E. M., Harland, R. M. and Kusumi, K. (2005). Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: clues from the BMP signaling pathway. Spine 30, 1379-1385. (Pubitemid 41754860)
-
(2005)
Spine
, vol.30
, Issue.12
, pp. 1379-1385
-
-
Schaffer, A.A.1
Kaplan, F.S.2
Tracy, M.R.3
O'Brien, M.L.4
Dormans, J.P.5
Shore, E.M.6
Harland, R.M.7
Kusumi, K.8
-
82
-
-
36448936383
-
TGFβ-SMAD signal transduction: Molecular specificity and functional flexibility
-
DOI 10.1038/nrm2297, PII NRM2297
-
Schmierer, B. and Hill, C. S. (2007). TGF-beta-SMAD signal transduction: molecular specificity and functional flexibility. Nat. Rev. Mol. Cell Biol. 8, 970-982. (Pubitemid 350174642)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.12
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
83
-
-
20844450082
-
Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA
-
DOI 10.1359/JBMR.050305
-
Serrano de la Peña, L., Billings, P. C., Fiori, J. L., Ahn, J., Kaplan, F. S. and Shore, E. M. (2005). Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA. J. Bone Miner. Res. 20, 1168-1176. (Pubitemid 40863804)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.7
, pp. 1168-1176
-
-
Serrano, D.L.P.L.1
Billings, P.C.2
Fiori, J.L.3
Ahn, J.4
Kaplan, F.S.5
Shore, E.M.6
-
84
-
-
0029746491
-
Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva
-
DOI 10.1056/NEJM199608223350804
-
Shafritz, A. B., Shore, E. M., Gannon, F. H., Zasloff, M. A., Taub, R., Muenke, M. and Kaplan, F. S. (1996). Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N. Engl. J. Med. 335, 555-561. (Pubitemid 26272310)
-
(1996)
New England Journal of Medicine
, vol.335
, Issue.8
, pp. 555-561
-
-
Shafritz, A.B.1
Shore, E.M.2
Gannon, F.H.3
Zasloff, M.A.4
Taub, R.5
Muenke, M.6
Kaplan, F.S.7
-
85
-
-
0028115971
-
Spinal deformity in patients who have fibrodysplasia ossificans progressiva
-
Shah, P. B., Zasloff, M. A., Drummond, D. and Kaplan, F. S. (1994). Spinal deformity in patients who have fibrodysplasia ossificans progressiva. J. Bone Joint Surg. Am. 76, 1442-1450. (Pubitemid 24355959)
-
(1994)
Journal of Bone and Joint Surgery - Series A
, vol.76
, Issue.10
, pp. 1442-1450
-
-
Shah, P.B.1
Zasloff, M.A.2
Drummond, D.3
Kaplan, F.S.4
-
86
-
-
70449366408
-
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
-
Shen, Q., Little, S. C., Xu, M., Haupt, J., Ast, C., Katagiri, T., Mundlos, S., Seemann, P., Kaplan, F. S., Mullins, M. C. et al. (2009). The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J. Clin. Invest. 119, 3462-3472.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3462-3472
-
-
Shen, Q.1
Little, S.C.2
Xu, M.3
Haupt, J.4
Ast, C.5
Katagiri, T.6
Mundlos, S.7
Seemann, P.8
Kaplan, F.S.9
Mullins, M.C.10
-
87
-
-
0038682002
-
Mechanisms of TGF-β signaling from cell membrane to the nucleus
-
DOI 10.1016/S0092-8674(03)00432-X
-
Shi, Y. and Massagué, J. (2003). Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113, 685-700. (Pubitemid 36724933)
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
88
-
-
79953736346
-
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-g agonists
-
Shimono, K., Tung, W. E., Macolino, C., Chi, A. H.-T., Didizian, J. H., Mundy, C., Chandraratna, R. A., Mishina, Y., Enomoto-Iwamoto, M., Pacifici, M. et al. (2011). Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-g agonists. Nat. Med. 17, 454-460.
-
(2011)
Nat. Med.
, vol.17
, pp. 454-460
-
-
Shimono, K.1
Tung, W.E.2
Macolino, C.3
Chi, A.H.-T.4
Didizian, J.H.5
Mundy, C.6
Chandraratna, R.A.7
Mishina, Y.8
Enomoto-Iwamoto, M.9
Pacifici, M.10
-
89
-
-
0029303670
-
MR imaging of myositis ossificans: Variable patterns at different stages
-
Shirkhoda, A., Armin, A.-R., Bis, K. G., Makris, J., Irwin, R. B. and Shetty, A. N. (1995). MR imaging of myositis ossificans: variable patterns at different stages. J. Magn. Reson. Imaging 5, 287-292.
-
(1995)
J. Magn. Reson. Imaging
, vol.5
, pp. 287-292
-
-
Shirkhoda, A.1
Armin, A.-R.2
Bis, K.G.3
Makris, J.4
Irwin, R.B.5
Shetty, A.N.6
-
90
-
-
77956275161
-
Inherited human diseases of heterotopic bone formation
-
Shore, E. M. and Kaplan, F. S. (2010). Inherited human diseases of heterotopic bone formation. Nat. Rev. Rheumatol. 6, 518-527.
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 518-527
-
-
Shore, E.M.1
Kaplan, F.S.2
-
91
-
-
25844453495
-
The genetics of fibrodysplasia ossificans progressiva
-
DOI 10.1385/BMM:3:3-4:201
-
Shore, E. M., Feldman, G. J., Xu, M. and Kaplan, F. S. (2005). The genetics of fibrodysplasia ossificans progressiva. CRBMM 3, 201-204. (Pubitemid 41400335)
-
(2005)
Clinical Reviews in Bone and Mineral Metabolism
, vol.3
, Issue.3-4
, pp. 201-204
-
-
Shore, E.M.1
Feldman, G.J.2
Xu, M.3
Kaplan, F.S.4
-
92
-
-
33646348736
-
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore, E. M., Xu, M., Feldman, G. J., Fenstermacher, D. A., Cho, T.-J., Choi, I. H., Connor, J. M., Delai, P., Glaser, D. L., LeMerrer, M. et al. (2006). A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat. Genet. 38, 525-527.
-
(2006)
Nat. Genet.
, vol.38
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
Fenstermacher, D.A.4
Cho, T.-J.5
Choi, I.H.6
Connor, J.M.7
Delai, P.8
Glaser, D.L.9
LeMerrer, M.10
-
93
-
-
77954588190
-
Molecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva
-
Song, G. A., Kim, H. J., Woo, K. M., Baek, J. H., Kim, G. S., Choi, J. Y. and Ryoo, H. M. (2010). Molecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva. J. Biol. Chem. 285, 22542-22553.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22542-22553
-
-
Song, G.A.1
Kim, H.J.2
Woo, K.M.3
Baek, J.H.4
Kim, G.S.5
Choi, J.Y.6
Ryoo, H.M.7
-
94
-
-
70649097373
-
Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2
-
Twombly, V., Bangi, E., Le, V., Malnic, B., Singer, M. A. and Wharton, K. A. (2009). Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2. Genetics 183, 563-579.
-
(2009)
Genetics
, vol.183
, pp. 563-579
-
-
Twombly, V.1
Bangi, E.2
Le, V.3
Malnic, B.4
Singer, M.A.5
Wharton, K.A.6
-
95
-
-
34250019537
-
Bone: Formation by autoinduction
-
Urist, M. R. (1965). Bone: formation by autoinduction. Science 150, 893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
96
-
-
77953497987
-
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation
-
van Dinther, M., Visser, N., de Gorter, D. J., Doorn, J., Goumans, M. J., de Boer, J. and ten Dijke, P. (2010). ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation. J. Bone Miner. Res. 25, 1208-1215.
-
(2010)
J. Bone Miner. Res.
, vol.25
, pp. 1208-1215
-
-
Van Dinther, M.1
Visser, N.2
De Gorter, D.J.3
Doorn, J.4
Goumans, M.J.5
De Boer, J.6
Ten Dijke, P.7
-
97
-
-
0036019926
-
Neurogenic heterotopic ossification in spinal cord injury
-
DOI 10.1038/sj.sc.3101309
-
van Kuijk, A. A., Geurts, A. C. H. and van Kuppevelt, H. J. M. (2002). Neurogenic heterotopic ossification in spinal cord injury. Spinal Cord 40, 313-326. (Pubitemid 34756209)
-
(2002)
Spinal Cord
, vol.40
, Issue.7
, pp. 313-326
-
-
Van Kuijk, A.A.1
Geurts, A.C.H.2
Van Kuppevelt, H.J.M.3
-
98
-
-
84857283030
-
Fibrodysplasia ossificans progressiva: Middle-age onset of heterotopic ossification from a unique missense mutation (c.974G>C, p.G325A) in ACVR1
-
Whyte, M. P., Wenkert, D., Demertzis, J. L., DiCarlo, E. F., Westenberg, E. and Mumm, S. (2012). Fibrodysplasia ossificans progressiva: middle-age onset of heterotopic ossification from a unique missense mutation (c.974G>C, p.G325A) in ACVR1. J. Bone Miner. Res. 27, 729-737.
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 729-737
-
-
Whyte, M.P.1
Wenkert, D.2
Demertzis, J.L.3
DiCarlo, E.F.4
Westenberg, E.5
Mumm, S.6
-
99
-
-
84859912590
-
Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification
-
Wosczyna, M. N., Biswas, A. A., Cogswell, C. A. and Goldhamer, D. J. (2012). Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification. J. Bone Miner. Res. 27, 1004-1017.
-
(2012)
J. Bone Miner. Res.
, vol.27
, pp. 1004-1017
-
-
Wosczyna, M.N.1
Biswas, A.A.2
Cogswell, C.A.3
Goldhamer, D.J.4
-
100
-
-
0024256133
-
Novel regulators of bone formation: Molecular clones and activities
-
Wozney, J. M., Rosen, V., Celeste, A. J., Mitsock, L. M., Whitters, M. J., Kriz, R. W., Hewick, R. M. and Wang, E. A. (1988). Novel regulators of bone formation: molecular clones and activities. Science 242, 1528-1534. (Pubitemid 19023695)
-
(1988)
Science
, vol.242
, Issue.4885
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
101
-
-
61749097816
-
Tgf-beta superfamily signaling in embryonic development and homeostasis
-
Wu, M. Y. and Hill, C. S. (2009). Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev. Cell 16, 329-343.
-
(2009)
Dev. Cell
, vol.16
, pp. 329-343
-
-
Wu, M.Y.1
Hill, C.S.2
-
102
-
-
57349171954
-
BMP type I receptor inhibition reduces heterotopic [corrected] ossification
-
Yu, P. B., Deng, D. Y., Lai, C. S., Hong, C. C., Cuny, G. D., Bouxsein, M. L., Hong, D. W., McManus, P. M., Katagiri, T., Sachidanandan, C. et al. (2008). BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat. Med. 14, 1363-1369.
-
(2008)
Nat. Med.
, vol.14
, pp. 1363-1369
-
-
Yu, P.B.1
Deng, D.Y.2
Lai, C.S.3
Hong, C.C.4
Cuny, G.D.5
Bouxsein, M.L.6
Hong, D.W.7
McManus, P.M.8
Katagiri, T.9
Sachidanandan, C.10
-
103
-
-
0031963441
-
Treatment of patients who have fibrodysplasia ossificans progressiva with isotretinoin
-
Zasloff, M. A., Rocke, D. M., Crofford, L. J., Hahn, G. V. and Kaplan, F. S. (1998). Treatment of patients who have fibrodysplasia ossificans progressiva with isotretinoin. Clin. Orthop. Relat. Res. 346, 121-129. (Pubitemid 28046876)
-
(1998)
Clinical Orthopaedics and Related Research
, Issue.346
, pp. 121-129
-
-
Zasloff, M.A.1
Rocke, D.M.2
Crofford, L.J.3
Hahn, G.V.4
Kaplan, F.S.5
-
104
-
-
0042978771
-
ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development
-
DOI 10.1359/jbmr.2003.18.9.1593
-
Zhang, D., Schwarz, E. M., Rosier, R. N., Zuscik, M. J., Puzas, J. E. and O'Keefe, R. J. (2003). ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J. Bone Miner. Res. 18, 1593-1604. (Pubitemid 37022917)
-
(2003)
Journal of Bone and Mineral Research
, vol.18
, Issue.9
, pp. 1593-1604
-
-
Zhang, D.1
Schwarz, E.M.2
Rosier, R.N.3
Zuscik, M.J.4
Puzas, J.E.5
O'Keefe, R.J.6
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