Urinary basic fibroblast growth factor: A biochemical marker for preosseous fibroproliferative lesions in patients with fibrodysplasia ossificans progressiva

Clinical Orthopaedics and Related Research

Volumn 346, Issue , 1998, Pages 59-65

  Kaplan, Frederick ^a   Sawyer, Jeffrey ^a   Connors, Susan ^b   Keough, Karen ^b   Shore, Eileen ^a   Gannon, Francis ^a   Glaser, David ^a   Rocke, David ^c   Zasloff, Michael ^a   Folkman, Judah ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; BASIC FIBROBLAST GROWTH FACTOR; BIOCHEMICAL MARKER; BONE MORPHOGENETIC PROTEIN; INTERLEUKIN 8; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADOLESCENT; ADULT; ANGIOGENESIS; BONE DEVELOPMENT; CHILD; CONFERENCE PAPER; CONTROLLED STUDY; CREATININE CLEARANCE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; OSSIFYING MYOSITIS; PRIORITY JOURNAL; SOLID TUMOR; URINALYSIS;

EID: 0031984797     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (42)

1. Abraham JA, Whang JL, Tumolo A, et al: Human basic fibroblast growth factor: Nucleotide sequence and genomic organization. EMBO J 5:2523-2528, 1986.
2. Basilico C, Moscatelli D: The FGF family of growth factors and oncogenes. Adv Cancer Res 59:115-165, 1992.
3. Brennan TJ, Edmondson DG, Li L, Olson EN: Transforming growth factor-beta represses the action of myogenin through a mechanism independent of DNA binding. Proc Natl Acad SCi USA 88:3822-3826, 1991.
4. Brogi E, Wu T, Namiki A, Isner JM: Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEFG expression only. Circulation 90:649-652, 1994.
5. Brooks PC, Montgomery AMP, Rosenfeld M, et al: Integrin alpha-V Beta-3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157-1164, 1994.
6. Cunningham NS, Paralkar V, Reddi AH: Osteogenin and recombinant bone morphogenetic protein 2B are chemotactic for human monocytes and stimulate transforming growth factor-beta-1 mRNA expression. Proc Natl Acad Sci USA 89:11740-11744, 1992.
7. Dellian M, Witwer BP, Salehi HA, Yuan F, Jain RK: Quantitation and physiological characterization of angiogenic vessels in mice. Am J Pathol 149:59-71, 1996.
8. Duprez DM, Coltey M, Amthor H, Brickell PM, Tickle C: Bone morphogenetic protein-2 (BMP-2) inhibits muscle development and promotes cartilage formation in chick limb bud cultures. Dev Biol 174:448-452, 1996.
9. Feinberg RN, Noden DM: Experimental analysis of blood vessel development in the avian wing bud. Anat Rec 231:136-144, 1991.
10. Fidler IJ, Ellis LM: The implications of angiogenesis for the biology and therapy of cancer metastasis (minireview). Cell 79:185-188, 1994.
11. Florini JR, Roberts AB, Ewton DZ, et al: Transforming growth factor-beta: A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by buffalo rat liver cells. J Biol Chem 261:16509-16513, 1986.
12. Folkman J: Clinical applications of research on angiogenesis. New Engl J Med 333:1757-1763, 1995.
13. Friedlander M, Brooks PC, Shaffer RW, et al: Definition of two angiogenic pathways by distinct alpha-V integrins. Science 270:1500-1502, 1995.
14. Friesel RE, Maciag T: Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB J 9:919-925, 1995.
15. Gendron RL, Tsai F-Y, Paradis H, Arceci RJ: Induction of embryonic vasculogenesis by bFGF and LIF in vitro and in vivo. Dev Biol 177:332-346, 1996.
16. Hallmann R, Feinberg RN, Latker CH, Sasse J, Risau W: Regression of blood vessels precedes cartilage differentiation during chick limb development. Differentiation 34:98-105, 1987.
17. Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis (review). Cell 86:353-364, 1996.
18. Harada S, Rodan SB, Rodan GA: Expression and regulation of vascular endothelial growth factor in osteoblasts. Clin Orthop 313:76-80, 1995.
19. Hurley MM, Abreu C, Marcello K, et al: Regulation of NFIL-6 and IL-6 expression by basic fibroblast growth factor in osteoblasts. J Bone Miner Res 11:760-767, 1996.
20. Iwamoto M, Shimazu A, Pacifici M: Regulation of chondrocyte maturation by fibroblast growth factor-2 and parathyroid hormone. J Orthop Res 13:838-845, 1995.
21. Kandel J, Bossy-Wetzel E, Radvanyi F, et al: Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell 66:1095-1104, 1991.
22. Kaplan FS, Tabas JA, Gannon FH, et al: The histopathology of fibrodysplasia ossificans progressiva: an endochondral process. J Bone Joint Surg 75A:220-230, 1993.
23. Kaplan FS, Tabas JA, Zasloff MA: Fibrodysplasia ossificans progressiva: A clue from the fly. Calcif Tissue Int 47:117-125, 1990.
24. Katagiri T, Yamaguchi A, Komaki M, et al: Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127:1755-1766, 1994.
25. Kato Y, Iwamoto M: Fibroblast growth factor is an inhibitor of chondrocyte terminal differentiation. J Biol Chem 10:5903-5909, 1990.
26. Li L, Zhou J, James G, et al: FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein Kinase C site in their DNA-binding domains. Cell 71:1181-1194, 1992.
27. Mason IJ: The ins and outs of fibroblast growth factors (meeting review). Cell 78:547-552, 1994.
28. Nguyen M, Watanabe H, Budson AE, et al: Elevated levels of an angiogenic peptide,basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J Natl Cancer Inst 86:356-361, 1994.
29. O'Reilly MS, Holmgren L, Shing Y, et al: Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79:315-328, 1995.
30. Pepper MS, Belin D, Montesano R, Orci L, Vassalli J-D: Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol 111:743-755, 1990.
31. Reddi AH, Cunningham NS: Initiation and promotion of bone differentiation by bone morphogenetic proteins. J Bone Miner Res 8(Suppl 2):S499-S502, 1993.
32. Senger DR: Molecular framework for angiogenesis. Am J Pathol 149:1-7, 1996.
33. Shafritz AB, Shore EM, Gannon FH, et al: Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N Engl J Med 335:555-561, 1996.
34. Shida J-I, Jingushi S, Izumi T, Iwaki A, Sugioka Y: Basic fibroblast growth factor stimulates articular cartilage enlargement in young rates in-vivo. J Bone Miner Res 14:265-272, 1996.
35. Shweiki D, Itin A, Soffer D, Keshet E: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia - initiated angiogenesis. Nature 359:843-845, 1992.
36. Snedecor GW, Cochran WG: Statistical Methods. Ed 7. Ames, Iowa State University 291, 1980.
37. Twal WO, Vasilatos-Younken R, Gay CV, Leach RM: Isolation and localization of basic fibroblast growth factor-immunoreactive substance in the epiphyseal growth plate. J Bone Miner Res 9:1737-1744, 1994.
38. Wang J-S, Aspenberg P: Basic fibroblast growth factor enhances bone-graft incorporation: Dose and time dependence in rats. J Orthop Res 14:316-323, 1996.
39. Weintraub H: The Myo D family and myogenesis: Redundancy, networks and thresholds. Cell 75:1241-1244, 1993.
40. Wroblewski J, Edwall-Arvidsson C: Inhibitory effects of basic fibroblast growth factor on chondrocyte differentiation. J Bone Miner Res 10:735-742, 1995.
41. Xu R-H, Dong Z, Maeno M, et al: Involvement of Ras/Raf/AP-1 in BMP-4 signalling during Xenopus embryonic development. Proc Natl Acad Sci USA 93:834-838, 1996.
42. Yamaguchi A, Katagiri T, Ikeda T, et al: Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J Cell Biol 113:681-687, 1991.