Loss of STAT6 promotes autoimmune disease and atopy on a susceptible genetic background

Journal of Autoimmunity

Volumn 39, Issue 4, 2012, Pages 388-397

  Lau, Maverick ^a,b   Tsantikos, Evelyn ^a   Maxwell, Mhairi J ^a   Tarlinton, David M ^c   Anderson, Gary P ^b   Hibbs, Margaret L ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Autoimmune disease; Immune response regulation; Signal transduction; Th2 traits

Indexed keywords

AUTOANTIBODY; CYTOKINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAT6 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; ATOPY; AUTOIMMUNE DISEASE; B LYMPHOCYTE; BASOPHIL; BONE MARROW CELL; CONTROLLED STUDY; DISEASE EXACERBATION; EOSINOPHILIA; GENE MUTATION; GENE REARRANGEMENT; GENETIC SUSCEPTIBILITY; IMMUNOGLOBULIN BLOOD LEVEL; KIDNEY DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH2 CELL;

AGE FACTORS; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ASTHMA; DISEASE MODELS, ANIMAL; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT6 TRANSCRIPTION FACTOR; TH2 CELLS;

EID: 84869890124     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.06.003     Document Type: Article

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