Swelling, erosion and release behavior of alginate-based matrix tablets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 66, Issue 3, 2007, Pages 435-450

  Sriamornsak, Pornsak ^a   Thirawong, Nartaya ^a   Korkerd, Kingkarn ^a  

^a SILPAKORN UNIVERSITY   (Thailand)

Author keywords

Alginate; Drug release; Erosion; Hydration; Matrix tablet; Swelling

Indexed keywords

ALGINIC ACID; AMMONIA; BICARBONATE; CALCIUM ACETATE; CALCIUM SALT; DRUG ADDITIVE; METRONIDAZOLE; PHOSPHATE BUFFERED SALINE;

AQUEOUS SOLUTION; ARTICLE; DRUG DIFFUSION; DRUG MECHANISM; DRUG RELEASE; EROSION; HYDRATION; MATRIX TABLET; PARTICLE SIZE; PH; TABLET DISINTEGRATION;

ACETATES; ALGINATES; CALCIUM COMPOUNDS; GLUCURONIC ACID; HARDNESS; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; METRONIDAZOLE; PARTICLE SIZE; SODIUM BICARBONATE; SOLUBILITY; TABLETS;

EID: 34248597393     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.12.003     Document Type: Article

References (21)

1. Haug A., and Larsen B. Quantitative determination of the uronic acid composition of alginates. Acta Chem. Scand. 16 (1962) 1908-1918
2. Haug A., Larsen B., and Smidsrod O. Studies on the sequence of uronic acid residues in alginic acid. Acta Chem. Scand. 21 (1967) 691-704
3. Clare K. Algin. In: Whistler R.L., and BeMiller J.N. (Eds). Industrial Gums. third ed. (1993), Academic Press, New York
4. Kudela V. Hydrogels. Encyclopedia of Polymer Science and Engineering vol. 7 (1987), Wiley, New York 703-807
5. Heller J., Helwing R.F., Baker R.W., and Tuttle M.E. Controlled release of water-soluble macromolecules from bioerodible hydrogel. Biomaterials 4 (1983) 262-266
6. Bamba M., Puisieux F., Marty J.P., and Carstensen J.T. Release mechanisms in gel forming sustained release preparations. Int. J. Pharm. 2 (1979) 307-315
7. Hodsdon A.C., Mitchell J.R., Davies M.C., and Melia C.D. Structure and behaviour in hydrophilic matrix sustained release dosage forms. 3. The influence of pH on the sustained-release performance and internal gel structure of sodium alginate matrices. J. Control. Release 33 (1995) 143-152
8. Melia C.D. Hydrophilic matrix sustained release systems based on polysaccharide carriers. Crit. Rev. Ther. Drug Carr. Syst. 8 (1991) 395-421
9. Veski P., and Marvola M. Sodium alginate as diluents in hard gelatin capsules containing ibuprofen as a model drug. Pharmazie 48 (1993) 757-760
10. Giunchedi, P., Gavini, E., Domenico, M., Moretti, L., Pirisino, G., 2000. Evaluation of alginate compressed matrices as prolonged drug delivery systems, AAPS PharmSciTech 1 (3), article 19. ().
11. Efentakis M., and Buckton G. The effect of erosion and swelling on the dissolution of theophylline from low and high viscosity sodium alginate matrices. Pharm. Dev. Technol. 7 (2002) 69-77
12. Liew C.V., Chan L.W., Ching A.L., and Heng P.W.S. Evaluation of sodium alginate as drug release modifier in matrix tablets. Int. J. Pharm. 309 (2006) 25-37
13. P. Sriamornsak, S. Sungthongjeen, Modification of theophylline release with alginate gel formed in hard capsules. AAPS PharmSciTech, accepted for publication.
14. Korsmeyer R.W., Gurny R., Docler E., Buri P., and Peppas N.A. Mechanism of solute release from porous hydrophilic polymers. Int. J. Pharm. 15 (1983) 25-35
15. Gustafsson C., Bonferoni M.C., Caramella C., Lennholm H., and Nystrom C. Characterisation of particle properties and compaction behaviour of hydroxypropyl methylcellulose with different degrees of methoxy/hydroxypropyl substitution. Eur. J. Pharm. Sci. 9 (1999) 171-184
16. Sriamornsak P., and Kennedy R.A. Development of polysaccharide gel coated pellets for oral administration. 2. Calcium alginate. Eur. J. Pharm. Sci. 29 (2006) 139-147
17. Vazquez M.J., Perez-Marcos B., Gomez-Amoza J.L., Martinez-Pacheco R., Souto C., and Concheiro A. Influence of technological variables on release of drugs from hydrophilic matrices. Drug Dev. Ind. Pharm. 18 (1992) 1355-1375
18. Velasco M.V., Ford J.L., Rowe P., and Rajabi-Siahboomi A.R. Influence of drug:hydroxypropylmethylcellulose ratio, drug and polymer particle size and compression force on the release of diclofenac sodium from HPMC tablets. J. Control. Release 57 (1999) 75-85
19. S. Sungthongjeen, P. Sriamornsak, T. Pitaksuteepong, A. Somsiri, S. Puttipipatkhachorn, Effect of degree of esterification and calcium amount on drug release from pectin-based matrix tablets. AAPS PharmSciTech, 5, (2004) article 9. ().
20. Siepmann J., and Peppas N.A. Modeling of drug release from delivery systems based on hydroxypropyl metylcellulose (HPMC). Adv. Drug Del. Rev. 48 (2001) 139-157
21. Khairuzzaman A., Ahmed S.U., Savva M., and Patel N.K. Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. Int. J. Pharm. 318 (2006) 15-21