Mechanisms of drug release in citrate buffered HPMC matrices

International Journal of Pharmaceutics

Volumn 370, Issue 1-2, 2009, Pages 110-120

  Pygall, Samuel R ^a   Kujawinski, Sarah ^a   Timmins, Peter ^b   Melia, Colin D ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Buffering; Citrate; Drug release; Hydrophilic matrix; Hydroxypropyl methyl cellulose; Mechanism

Indexed keywords

BUFFER; CITRATE SODIUM; FELBINAC; GLUCOSE; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NONSTEROID ANTIINFLAMMATORY AGENT;

ACIDITY; ARTICLE; CONCENTRATION (PARAMETERS); DIFFUSION; DISSOLUTION; DRUG RELEASE; DRUG SOLUBILITY; FLOW KINETICS; GEL; HYDROPHILICITY; MATRIX TABLET; PARTICLE SIZE; PH; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BUFFERS; CHEMISTRY, PHARMACEUTICAL; CITRATES; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; EXCIPIENTS; GELS; HYDROGEN-ION CONCENTRATION; KINETICS; LACTOSE; METHYLCELLULOSE; MODELS, CHEMICAL; PHENYLACETATES; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 61449210959     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.11.022     Document Type: Article

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