Glutathione Depletion and Carbon Ion Radiation Potentiate Clustered DNA Lesions, Cell Death and Prevent Chromosomal Changes in Cancer Cells Progeny

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Hanot, Maïté ^a,b   Boivin, Anthony ^a   Malésys, Céline ^a   Beuve, Michaël ^a   Colliaux, Anthony ^a   Foray, Nicolas ^a   Douki, Thierry ^c   Ardail, Dominique ^a   Rodriguez Lafrasse, Claire ^a,d  

^a UNIVERSITÉ LYON 1   (France)

^b Fondation Synergie Lyon Cancer   (France)

^c DIF   (France)

^d CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTHIONINE SULFOXIMINE; CARBON; DNA; FUMARIC ACID DIMETHYL ESTER; GLUTATHIONE; HISTONE H2AX;

ARTICLE; CANCER CELL CULTURE; CELL DEATH; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME LOSS; CHROMOSOME REARRANGEMENT; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DOUBLE STRANDED DNA BREAK; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROGENY; PROTEIN CONTENT; PROTEIN DEPLETION; PROTEIN EXPRESSION; RADIOSENSITIVITY; X IRRADIATION;

BUTHIONINE SULFOXIMINE; CARBON; CELL CYCLE CHECKPOINTS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMOSOMES, HUMAN; CLONE CELLS; CLUSTER ANALYSIS; DNA BREAKS, DOUBLE-STRANDED; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; FUMARATES; GENE REARRANGEMENT; GLUTATHIONE; HISTONES; HUMANS; IONS; KINETICS; MICRONUCLEUS TESTS; NEOPLASMS; RADIATION; X-RAYS;

EID: 84869803901     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044367     Document Type: Article

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