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Volumn 50, Issue 1, 2009, Pages 1-9

Recent insights into the biological action of heavy-ion radiation

Author keywords

[No Author keywords available]

Indexed keywords

BEER; CYTOLOGY; ENERGY TRANSFER; GAMMA RAYS; GENE EXPRESSION; NITRIC OXIDE; TUMORS;

EID: 55149103353     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.08070     Document Type: Article
Times cited : (73)

References (124)
  • 1
    • 44349188585 scopus 로고    scopus 로고
    • Formation of clustered DNA damage after high-LET irradiation: a review
    • Hada, M. and Georgakilas, A. G. (2008) Formation of clustered DNA damage after high-LET irradiation: a review. J. Radiat. Res. 49: 203-210.
    • (2008) J. Radiat. Res. , vol.49 , pp. 203-210
    • Hada, M.1    Georgakilas, A.G.2
  • 2
    • 0031797976 scopus 로고    scopus 로고
    • Heavy-ion radiobiology: New approaches to delineate mechanisms underlying enhanced biological effectiveness
    • Blakely, E. A. and Kronenberg, A. (1998) Heavy-ion radiobiology: new approaches to delineate mechanisms underlying enhanced biological effectiveness. Radiat. Res. 150: S126-S145.
    • (1998) Radiat. Res. , vol.150
    • Blakely, E.A.1    Kronenberg, A.2
  • 6
    • 18044384245 scopus 로고    scopus 로고
    • Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    • Ando, K., Koike, S., Uzawa, A., Takai, N., Fukawa, T., Furusawa, Y., Aoki, M. and Miyato, Y. (2005) Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice. J. Radiat. Res. 46: 51-57.
    • (2005) J. Radiat. Res. , vol.46 , pp. 51-57
    • Ando, K.1    Koike, S.2    Uzawa, A.3    Takai, N.4    Fukawa, T.5    Furusawa, Y.6    Aoki, M.7    Miyato, Y.8
  • 11
    • 33947535720 scopus 로고    scopus 로고
    • Particle radiation therapy using proton and heavier ion beams
    • Schulz-Ertner, D. and Tsujii, H. (2007) Particle radiation therapy using proton and heavier ion beams. J. Clin. Oncol. 25: 953-964.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 953-964
    • Schulz-Ertner, D.1    Tsujii, H.2
  • 13
    • 33645991783 scopus 로고    scopus 로고
    • Cancer risk from exposure to galactic cosmic rays: Implications for space exploration by human beings
    • Cucinotta, F. A. and Durante, M. (2006) Cancer risk from exposure to galactic cosmic rays: implications for space exploration by human beings. Lancet Oncol. 7: 431-435.
    • (2006) Lancet Oncol. , vol.7 , pp. 431-435
    • Cucinotta, F.A.1    Durante, M.2
  • 14
    • 0022271206 scopus 로고
    • Neon-20 ion- and X-ray-induced mammary carcinogenesis in female rats
    • Shellabarger, C. J., Baum, J. W., Holtzman, S. and Stone, J. P. (1985) Neon-20 ion- and X-ray-induced mammary carcinogenesis in female rats. Ann. N. Y. Acad. Sci. 459: 239-244.
    • (1985) Ann. N. Y. Acad. Sci. , vol.459 , pp. 239-244
    • Shellabarger, C.J.1    Baum, J.W.2    Holtzman, S.3    Stone, J.P.4
  • 18
    • 50649083893 scopus 로고    scopus 로고
    • Heavy-ion microbeams - development and applications in biological studies
    • Funayama, T., Hamada, N., Sakashita, T. and Kobayashi, Y. (2008) Heavy-ion microbeams - development and applications in biological studies. IEEE Trans. Plasma Sci. 36: 1432-1440.
    • (2008) IEEE Trans. Plasma Sci. , vol.36 , pp. 1432-1440
    • Funayama, T.1    Hamada, N.2    Sakashita, T.3    Kobayashi, Y.4
  • 19
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of α-particles
    • Nagasawa, H. and Little, J. B. (1992) Induction of sister chromatid exchanges by extremely low doses of α-particles. Cancer Res. 52: 6394-6396.
    • (1992) Cancer Res. , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 20
    • 4544234897 scopus 로고    scopus 로고
    • Targeted cytoplasmic irradiation induces bystander responses
    • Proc. Natl. Acad. Sci. USA
    • Shao, C., Folkard, M., Michael, B. D. and Prise, K. M. (2004) Targeted cytoplasmic irradiation induces bystander responses. Proc. Natl. Acad. Sci. USA 101: 13495-13500.
    • (2004) , vol.101 , pp. 13495-13500
    • Shao, C.1    Folkard, M.2    Michael, B.D.3    Prise, K.M.4
  • 21
    • 34250879092 scopus 로고    scopus 로고
    • Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells
    • Tartier, L., Gilchrist, S., Burdak-Rothkamm, S., Folkard, M. and Prise, K. M. (2007) Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res. 67: 5872-5879.
    • (2007) Cancer Res. , vol.67 , pp. 5872-5879
    • Tartier, L.1    Gilchrist, S.2    Burdak-Rothkamm, S.3    Folkard, M.4    Prise, K.M.5
  • 22
    • 33846834182 scopus 로고    scopus 로고
    • Non-targeted bystander effects induced by ionizing radiation
    • Morgan, W. F. and Sowa, M. B. (2007) Non-targeted bystander effects induced by ionizing radiation. Mutat. Res. 616: 159-164.
    • (2007) Mutat. Res. , vol.616 , pp. 159-164
    • Morgan, W.F.1    Sowa, M.B.2
  • 23
    • 39749144505 scopus 로고    scopus 로고
    • Epigenetic changes and nontargted radiation effects - Is there a link?
    • Kovalchuk, O. and Baulch, J. E. (2008) Epigenetic changes and nontargted radiation effects - Is there a link? Environ. Mol. Mutagen. 49: 16-25.
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 16-25
    • Kovalchuk, O.1    Baulch, J.E.2
  • 24
    • 33646037641 scopus 로고    scopus 로고
    • Bystander effect: Biological endpoints and microarray analysis
    • Chaudhry, M. A. (2006) Bystander effect: biological endpoints and microarray analysis. Mutat. Res. 597: 98-112.
    • (2006) Mutat. Res. , vol.597 , pp. 98-112
    • Chaudhry, M.A.1
  • 26
    • 34047241893 scopus 로고    scopus 로고
    • Intercellular and intracellular signaling pathways mediating ionizing radiation-induced bystander effects
    • Hamada, N., Matsumoto, H., Hara, T. and Kobayashi, Y. (2007) Intercellular and intracellular signaling pathways mediating ionizing radiation-induced bystander effects. J. Radiat. Res. 48: 87-95.
    • (2007) J. Radiat. Res. , vol.48 , pp. 87-95
    • Hamada, N.1    Matsumoto, H.2    Hara, T.3    Kobayashi, Y.4
  • 27
    • 34047202420 scopus 로고    scopus 로고
    • Vanguards of paradigm shift in radiation biology: Radiation-induced adaptive and bystander responses
    • Matsumoto, H., Hamada, N., Takahashi, A., Kobayashi, Y. and Ohnishi, T. (2007) Vanguards of paradigm shift in radiation biology: radiation-induced adaptive and bystander responses. J. Radiat. Res. 48: 97-106.
    • (2007) J. Radiat. Res. , vol.48 , pp. 97-106
    • Matsumoto, H.1    Hamada, N.2    Takahashi, A.3    Kobayashi, Y.4    Ohnishi, T.5
  • 31
    • 0036687419 scopus 로고    scopus 로고
    • Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology
    • Belka, C. and Budach, W. (2002) Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology. Int. J. Radiat. Biol. 78: 643-658.
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 643-658
    • Belka, C.1    Budach, W.2
  • 33
    • 33745863017 scopus 로고    scopus 로고
    • Drug insight: Cancer therapy strategies based on restoration of endogenous cell death mechanisms
    • Reed, J. C. (2006) Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms. Nat. Clin. Pract. Oncol. 3: 388-398.
    • (2006) Nat. Clin. Pract. Oncol. , vol.3 , pp. 388-398
    • Reed, J.C.1
  • 35
    • 38048999665 scopus 로고    scopus 로고
    • Two faces of p53: Aging and tumor suppression
    • Rodier, F., Campisi, J. and Bhaumik, D. (2007) Two faces of p53: aging and tumor suppression. Nucleic Acids Res. 35: 7475-7484.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7475-7484
    • Rodier, F.1    Campisi, J.2    Bhaumik, D.3
  • 39
    • 0035400225 scopus 로고    scopus 로고
    • High linear energy transfer carbon radiation effectively kills cultured glioma cells with either mutant or wild-type p53
    • Iwadate, Y., Mizoe, J., Osaka, Y., Yamaura, A. and Tsujii, H. (2001) High linear energy transfer carbon radiation effectively kills cultured glioma cells with either mutant or wild-type p53. Int. J. Radiat. Oncol. Biol. Phys. 50: 803-808.
    • (2001) Int. J. Radiat. Oncol. Biol. Phys. , vol.50 , pp. 803-808
    • Iwadate, Y.1    Mizoe, J.2    Osaka, Y.3    Yamaura, A.4    Tsujii, H.5
  • 40
    • 34547129096 scopus 로고    scopus 로고
    • Cell cycle checkpoint and apoptosis induction in glioblastoma cells and fibroblasts irradiated with carbon beam
    • Tsuboi, K., Moritake, T., Tsuchida, Y., Tokuuye, K., Matsumura, A. and Ando, K. (2007) Cell cycle checkpoint and apoptosis induction in glioblastoma cells and fibroblasts irradiated with carbon beam. J. Radiat. Res. 48: 317-325.
    • (2007) J. Radiat. Res. , vol.48 , pp. 317-325
    • Tsuboi, K.1    Moritake, T.2    Tsuchida, Y.3    Tokuuye, K.4    Matsumura, A.5    Ando, K.6
  • 41
  • 42
    • 0031920296 scopus 로고    scopus 로고
    • Apoptosis induced by heavy ion (carbon) irradiation of two human tumours with different radiosensitivities in vivo: Relative biological effectiveness (RBE) of carbon beam
    • Takahashi, T., Mitsuhashi, N., Furuta, M., Hasegawa, M., Ohno, T., Saito, Y., Sakurai, H., Nakano, T. and Niibe, H. (1998) Apoptosis induced by heavy ion (carbon) irradiation of two human tumours with different radiosensitivities in vivo: relative biological effectiveness (RBE) of carbon beam. Anticancer Res. 18: 253-256.
    • (1998) Anticancer Res. , vol.18 , pp. 253-256
    • Takahashi, T.1    Mitsuhashi, N.2    Furuta, M.3    Hasegawa, M.4    Ohno, T.5    Saito, Y.6    Sakurai, H.7    Nakano, T.8    Niibe, H.9
  • 43
    • 42149091693 scopus 로고    scopus 로고
    • Hypoxic tumor cell radiosensitization: role of the iNOS/NO pathway
    • De Ridder, M., Van Esch, G., Engels, B., Verovski, V. and Storme, G. (2008) Hypoxic tumor cell radiosensitization: role of the iNOS/NO pathway. Bull. Cancer 95: 282-291.
    • (2008) Bull. Cancer , vol.95 , pp. 282-291
    • De Ridder, M.1    Van Esch, G.2    Engels, B.3    Verovski, V.4    Storme, G.5
  • 45
    • 0042871531 scopus 로고    scopus 로고
    • Significance of the response of quiescent cell populations within solid tumors in cancer therapy
    • Masunaga, S. and Ono, K. (2002) Significance of the response of quiescent cell populations within solid tumors in cancer therapy. J. Radiat. Res. 43: 11-25.
    • (2002) J. Radiat. Res. , vol.43 , pp. 11-25
    • Masunaga, S.1    Ono, K.2
  • 46
    • 33646249643 scopus 로고    scopus 로고
    • Carbon beam therapy overcomes the radiation resistance of uterine cervical cancer originating from hypoxia
    • Nakano, T., Suzuki, Y., Ohno, T., Kato, S., Suzuki, M., Morita, S., Sato, S., Oka, K. and Tsujii, H. (2006) Carbon beam therapy overcomes the radiation resistance of uterine cervical cancer originating from hypoxia. Clin. Cancer Res. 12: 2185-2190.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2185-2190
    • Nakano, T.1    Suzuki, Y.2    Ohno, T.3    Kato, S.4    Suzuki, M.5    Morita, S.6    Sato, S.7    Oka, K.8    Tsujii, H.9
  • 47
    • 0034691130 scopus 로고    scopus 로고
    • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
    • Proc. Natl. Acad. Sci. USA
    • Wang, J. L., Liu, D., Zhang, Z. J., Shan, S., Han, X., Srinivasula, S. M., Croce, C. M., Alnemri, E. S. and Huang, Z. (2000) Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc. Natl. Acad. Sci. USA 97: 7124-7129.
    • (2000) , vol.97 , pp. 7124-7129
    • Wang, J.L.1    Liu, D.2    Zhang, Z.J.3    Shan, S.4    Han, X.5    Srinivasula, S.M.6    Croce, C.M.7    Alnemri, E.S.8    Huang, Z.9
  • 48
    • 33645059697 scopus 로고    scopus 로고
    • The small-organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death
    • Manero, F., Gautier, F., Gallenne, T., Cauquil, N., Gree, D., Cartron, P. F., Geneste, O., Gree, R., Vallette, F. M. and Juin, P. (2006) The small-organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death. Cancer Res. 66: 2757-2764.
    • (2006) Cancer Res. , vol.66 , pp. 2757-2764
    • Manero, F.1    Gautier, F.2    Gallenne, T.3    Cauquil, N.4    Gree, D.5    Cartron, P.F.6    Geneste, O.7    Gree, R.8    Vallette, F.M.9    Juin, P.10
  • 49
    • 33846807693 scopus 로고    scopus 로고
    • Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor
    • An, J., Chervin, A. S., Nie, A., Ducoff, H. S. and Huang, Z. (2007) Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. Oncogene 26: 652-661.
    • (2007) Oncogene , vol.26 , pp. 652-661
    • An, J.1    Chervin, A.S.2    Nie, A.3    Ducoff, H.S.4    Huang, Z.5
  • 51
    • 0023682831 scopus 로고
    • Radiosensitization produced by iododeoxyuridine with high linear energy transfer heavy ion beams
    • Linstadt, D., Blakely, E., Phillips, T. L. and Castro, J. R. (1988) Radiosensitization produced by iododeoxyuridine with high linear energy transfer heavy ion beams. Int. J. Radiat. Oncol. Biol. Phys. 15: 703-710.
    • (1988) Int. J. Radiat. Oncol. Biol. Phys. , vol.15 , pp. 703-710
    • Linstadt, D.1    Blakely, E.2    Phillips, T.L.3    Castro, J.R.4
  • 52
    • 38949108587 scopus 로고    scopus 로고
    • Recent developments in taxane drug delivery
    • Safavy, A. (2008) Recent developments in taxane drug delivery. Curr. Drug Deliv. 5: 42-54.
    • (2008) Curr. Drug Deliv. , vol.5 , pp. 42-54
    • Safavy, A.1
  • 53
    • 33746457945 scopus 로고    scopus 로고
    • Synergistic growth suppression induced in esophageal squamous cell carcinoma cells by combined treatment with docetaxel and heavy carbon-ion beam irradiation
    • Kitabayashi, H., Shimada, H., Yamada, S., Yasuda, S., Kamata, T., Ando, K., Tsujii, H. and Ochiai, T. (2006) Synergistic growth suppression induced in esophageal squamous cell carcinoma cells by combined treatment with docetaxel and heavy carbon-ion beam irradiation. Oncol. Rep. 15: 913-918.
    • (2006) Oncol. Rep. , vol.15 , pp. 913-918
    • Kitabayashi, H.1    Shimada, H.2    Yamada, S.3    Yasuda, S.4    Kamata, T.5    Ando, K.6    Tsujii, H.7    Ochiai, T.8
  • 54
    • 34249817885 scopus 로고    scopus 로고
    • Combining radiation and cancer gene therapy: a potential marriage of physical and biological targeting?
    • Hingorani, M., White, C. L., Agrawal, V. K., Vidal, L., Melcher, A. and Harrington, K. J. (2007) Combining radiation and cancer gene therapy: a potential marriage of physical and biological targeting? Curr. Cancer Drug Targets 7: 389-409.
    • (2007) Curr. Cancer Drug Targets , vol.7 , pp. 389-409
    • Hingorani, M.1    White, C.L.2    Agrawal, K.3    Vidal, L.4    Melcher, A.5    Harrington, K.J.6
  • 55
    • 16644373596 scopus 로고    scopus 로고
    • Growth suppression of esophageal squamous cell carcinoma induced by heavy carbon-ion beams combined with p53 gene transfer
    • Oohira, G., Yamada, S., Ochiai, T., Matsubara, H., Okazumi, S., Ando, K., Tsujii, H., Hiwasa, T. and Shimada, H. (2004) Growth suppression of esophageal squamous cell carcinoma induced by heavy carbon-ion beams combined with p53 gene transfer. Int. J. Oncol. 25: 563-569.
    • (2004) Int. J. Oncol. , vol.25 , pp. 563-569
    • Oohira, G.1    Yamada, S.2    Ochiai, T.3    Matsubara, H.4    Okazumi, S.5    Ando, K.6    Tsujii, H.7    Hiwasa, T.8    Shimada, H.9
  • 56
    • 33947106069 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer sensitizes hepatocellular carcinoma cells to heavy-ion radiation
    • Liu, B., Zhang, H., Zhou, G., Xie, Y., Hao, J., Qiu, R., Duan, X. and Zhou, Q. (2007) Adenovirus-mediated p53 gene transfer sensitizes hepatocellular carcinoma cells to heavy-ion radiation. J. Gastroenterol. 42: 140-145.
    • (2007) J. Gastroenterol. , vol.42 , pp. 140-145
    • Liu, B.1    Zhang, H.2    Zhou, G.3    Xie, Y.4    Hao, J.5    Qiu, R.6    Duan, X.7    Zhou, Q.8
  • 58
    • 40049092756 scopus 로고    scopus 로고
    • Apoptosis of murine melanoma cells induced by heavy-ion radiation combined with Tp53 gene transfer
    • Duan, X., Zhang, H., Liu, B., Li, X. D., Gao, Q. X. and Wu, Z. H. (2008) Apoptosis of murine melanoma cells induced by heavy-ion radiation combined with Tp53 gene transfer. Int. J. Radiat. Biol. 84: 211-217.
    • (2008) Int. J. Radiat. Biol. , vol.84 , pp. 211-217
    • Duan, X.1    Zhang, H.2    Liu, B.3    Li, X.D.4    Gao, Q.X.5    Wu, Z.H.6
  • 59
    • 0030743963 scopus 로고    scopus 로고
    • High-efficiency stable gene transfer of adenovirus into mammalian cells using ionizing radiation
    • Zeng, M., Cerniglia, G. J., Eck, S. L. and Stevens, C. W. (1997) High-efficiency stable gene transfer of adenovirus into mammalian cells using ionizing radiation. Hum. Gene Ther. 8: 1025-1032.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1025-1032
    • Zeng, M.1    Cerniglia, G.J.2    Eck, S.L.3    Stevens, C.W.4
  • 60
    • 42149128893 scopus 로고    scopus 로고
    • The role of hyperthermia in optimizing tumor response to regional therapy
    • Moyer, H. R. and Delman, K. A. (2008) The role of hyperthermia in optimizing tumor response to regional therapy. Int. J. Hyperthermia 24: 251-261.
    • (2008) Int. J. Hyperthermia , vol.24 , pp. 251-261
    • Moyer, H.R.1    Delman, K.A.2
  • 65
    • 34748860378 scopus 로고    scopus 로고
    • Pharmacologic approaches to radiation protection
    • Brizel, D. M. (2007) Pharmacologic approaches to radiation protection. J. Clin. Oncol. 25: 4084-4089.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4084-4089
    • Brizel, D.M.1
  • 66
    • 0036770087 scopus 로고    scopus 로고
    • Drinking beer reduces radiation-induced chromosome aberrations in human lymphocytes
    • Monobe, M. and Ando, K. (2002) Drinking beer reduces radiation-induced chromosome aberrations in human lymphocytes. J. Radiat. Res. 43: 237-245.
    • (2002) J. Radiat. Res. , vol.43 , pp. 237-245
    • Monobe, M.1    Ando, K.2
  • 67
    • 0037756730 scopus 로고    scopus 로고
    • β-pseudouridine, a beer component, reduces radiation-induced chromosome aberrations in human lymphocytes
    • Monobe, M., Arimoto-Kobayashi, S. and Ando, K. (2003) β-pseudouridine, a beer component, reduces radiation-induced chromosome aberrations in human lymphocytes. Mutat. Res. 538: 93-99.
    • (2003) Mutat. Res. , vol.538 , pp. 93-99
    • Monobe, M.1    Arimoto-Kobayashi, S.2    Ando, K.3
  • 68
    • 2942576589 scopus 로고    scopus 로고
    • Effects of beer administration in mice on acute toxicities induced by X rays and carbon ions
    • Monobe, M., Koike, S., Uzawa, A. and Ando, K. (2003) Effects of beer administration in mice on acute toxicities induced by X rays and carbon ions. J. Radiat. Res. 44: 75-80.
    • (2003) J. Radiat. Res. , vol.44 , pp. 75-80
    • Monobe, M.1    Koike, S.2    Uzawa, A.3    Ando, K.4
  • 69
    • 18044380500 scopus 로고    scopus 로고
    • Glycine betaine, a beer component, protects radiation-induced injury
    • Monobe, M., Uzawa, A., Hino, M., Ando, K. and Kojima, S. (2005) Glycine betaine, a beer component, protects radiation-induced injury. J. Radiat. Res. 46: 117-121.
    • (2005) J. Radiat. Res. , vol.46 , pp. 117-121
    • Monobe, M.1    Uzawa, A.2    Hino, M.3    Ando, K.4    Kojima, S.5
  • 70
    • 34347378502 scopus 로고    scopus 로고
    • Effects of glycine betaine on bone marrow death and intestinal damage by γ-rays and carbon ions
    • Monobe, M., Hamano, N., Sumi, M., Mukai, K., Moritake, T., Anzai, K., Uzawa, A. and Ando, K. (2006) Effects of glycine betaine on bone marrow death and intestinal damage by γ-rays and carbon ions. Radiat. Prot. Dosim. 122: 494-497.
    • (2006) Radiat. Prot. Dosim. , vol.122 , pp. 494-497
    • Monobe, M.1    Hamano, N.2    Sumi, M.3    Mukai, K.4    Moritake, T.5    Anzai, K.6    Uzawa, A.7    Ando, K.8
  • 71
    • 34547107081 scopus 로고    scopus 로고
    • A radiobiological review on melatonin: a novel radioprotector
    • Shirazi, A., Ghobadi, G. and Ghazi-Khansari, M. (2007) A radiobiological review on melatonin: a novel radioprotector. J. Radiat. Res. 48: 263-272.
    • (2007) J. Radiat. Res. , vol.48 , pp. 263-272
    • Shirazi, A.1    Ghobadi, G.2    Ghazi-Khansari, M.3
  • 73
    • 34248178271 scopus 로고    scopus 로고
    • Protective effects of L-selenomethionine on space radiation induced changes in gene expression
    • Stewart, J., Ko, Y. H. and Kennedy, A. R. (2007) Protective effects of L-selenomethionine on space radiation induced changes in gene expression. Radiat. Environ. Biophys. 46: 161-165.
    • (2007) Radiat. Environ. Biophys. , vol.46 , pp. 161-165
    • Stewart, J.1    Ko, Y.H.2    Kennedy, A.R.3
  • 74
    • 39249084374 scopus 로고    scopus 로고
    • Temporally distinct response of irradiated normal human fibroblasts and their bystander cells to energetic heavy ions
    • Hamada, N., Ni, M., Funayama, T., Sakashita, T. and Kobayashi, Y. (2008) Temporally distinct response of irradiated normal human fibroblasts and their bystander cells to energetic heavy ions. Mutat. Res. 639: 35-44.
    • (2008) Mutat. Res. , vol.639 , pp. 35-44
    • Hamada, N.1    Ni, M.2    Funayama, T.3    Sakashita, T.4    Kobayashi, Y.5
  • 76
    • 49649115515 scopus 로고    scopus 로고
    • Expression profiles are different in carbon ion-irradiated normal human fibroblasts and their bystander cells
    • Iwakawa, M., Hamada, N., Imadome, K., Funayama, T., Sakashita, T., Kobayashi, Y. and Imai, T. (2008) Expression profiles are different in carbon ion-irradiated normal human fibroblasts and their bystander cells. Mutat. Res. 642: 57-67.
    • (2008) Mutat. Res. , vol.642 , pp. 57-67
    • Iwakawa, M.1    Hamada, N.2    Imadome, K.3    Funayama, T.4    Sakashita, T.5    Kobayashi, Y.6    Imai, T.7
  • 77
    • 27744559469 scopus 로고    scopus 로고
    • Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts
    • Sokolov, M. V., Smilenov, L. B., Hall, E. J., Panyutin, I. G., Bonner, W. M. and Sedelnikova, O. A. (2005) Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts. Oncogene 24: 7257-7265.
    • (2005) Oncogene , vol.24 , pp. 7257-7265
    • Sokolov, M.V.1    Smilenov, L.B.2    Hall, E.J.3    Panyutin, G.4    Bonner, W.M.5    Sedelnikova, O.A.6
  • 78
    • 35148834590 scopus 로고    scopus 로고
    • γ-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication
    • Sokolov, M. V., Dickey, J. S., Bonner, W. M. and Sedelnikova, O. A. (2007) γ-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication. Cell Cycle 6: 2210-2212.
    • (2005) Cell Cycle , vol.6 , pp. 2210-2212
    • Sokolov, M.V.1    Dickey, J.S.2    Bonner, W.M.3    Sedelnikova, O.A.4
  • 80
    • 7644234070 scopus 로고    scopus 로고
    • Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response
    • Kadhim, M. A., Moore, S. R. and Goodwin, E. H. (2004) Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response. Mutat. Res. 568: 21-32.
    • (2004) Mutat. Res. , vol.568 , pp. 21-32
    • Kadhim, M.A.1    Moore, S.R.2    Goodwin, E.H.3
  • 81
    • 33646488069 scopus 로고    scopus 로고
    • Untargeted effects of ionizing radiation: Implications for radiation pathology
    • Wright, E. G. and Coates, P. J. (2006) Untargeted effects of ionizing radiation: implications for radiation pathology. Mutat. Res. 597: 119-132.
    • (2006) Mutat. Res. , vol.597 , pp. 119-132
    • Wright, E.G.1    Coates, P.J.2
  • 82
    • 33750616552 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: A review
    • Kim, G. J., Chandrasekaran, K. and Morgan, W. F. (2006) Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review. Mutagenesis 21: 361-367.
    • (2006) Mutagenesis , vol.21 , pp. 361-367
    • Kim, G.J.1    Chandrasekaran, K.2    Morgan, W.F.3
  • 84
    • 37149045307 scopus 로고    scopus 로고
    • Energetic heavy ions accelerate differentiation in the descendants of irradiated normal human diploid fibroblasts
    • Hamada, N., Hara, T., Funayama, T., Sakashita, T. and Kobayashi, Y. (2008) Energetic heavy ions accelerate differentiation in the descendants of irradiated normal human diploid fibroblasts. Mutat. Res. 637: 190-196.
    • (2008) Mutat. Res. , vol.637 , pp. 190-196
    • Hamada, N.1    Hara, T.2    Funayama, T.3    Sakashita, T.4    Kobayashi, Y.5
  • 85
  • 87
    • 0041709202 scopus 로고    scopus 로고
    • Bystander effect induced by counted high-LET particles in confluent human fibroblasts: a mechanistic study
    • Shao, C., Furusawa, Y., Kobayashi, Y., Funayama, T. and Wada, S. (2003) Bystander effect induced by counted high-LET particles in confluent human fibroblasts: a mechanistic study. FASEB J. 17: 1422-1427.
    • (2003) FASEB J. , vol.17 , pp. 1422-1427
    • Shao, C.1    Furusawa, Y.2    Kobayashi, Y.3    Funayama, T.4    Wada, S.5
  • 88
    • 0041317777 scopus 로고    scopus 로고
    • Role of gap junctional intercellular communication in radiation-induced bystander effects in human fibroblasts
    • Shao, C., Furusawa, Y., Aoki, M. and Ando, K. (2003) Role of gap junctional intercellular communication in radiation-induced bystander effects in human fibroblasts. Radiat. Res. 160: 318-323.
    • (2003) Radiat. Res. , vol.160 , pp. 318-323
    • Shao, C.1    Furusawa, Y.2    Aoki, M.3    Ando, K.4
  • 89
    • 33748331392 scopus 로고    scopus 로고
    • Involvement of gap junctional intercellular communication in the bystander effect induced by broad-beam or microbeam heavy ions
    • Shao, C., Furusawa, Y., Kobayashi, Y. and Funayama, T. (2006) Involvement of gap junctional intercellular communication in the bystander effect induced by broad-beam or microbeam heavy ions. Nucl. Instr. Meth. Phys. Res. B 251: 177-181.
    • (2006) Nucl. Instr. Meth. Phys. Res. B , vol.251 , pp. 177-181
    • Shao, C.1    Furusawa, Y.2    Kobayashi, Y.3    Funayama, T.4
  • 90
    • 20044363661 scopus 로고    scopus 로고
    • Heavy charged particles produce a bystander effect via cell-cell junctions
    • Suzuki, M. and Tsuruoka, C. (2004) Heavy charged particles produce a bystander effect via cell-cell junctions. Biol. Sci. Space 18: 241-246.
    • (2004) Biol. Sci. Space , vol.18 , pp. 241-246
    • Suzuki, M.1    Tsuruoka, C.2
  • 92
    • 35348834232 scopus 로고    scopus 로고
    • The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts
    • Yang, H., Anzenberg, V. and Held, K. D. (2007) The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts. Radiat. Res. 168: 292-298.
    • (2007) Radiat. Res. , vol.168 , pp. 292-298
    • Yang, H.1    Anzenberg, V.2    Held, K.D.3
  • 93
    • 34748869581 scopus 로고    scopus 로고
    • Effects of heavy ions and energetic protons on normal human fibroblasts
    • Yang, H., Anzenberg, V. and Held, K. D. (2007) Effects of heavy ions and energetic protons on normal human fibroblasts. Radiats. Biol. Radioecol. 47: 302-306.
    • (2007) Radiats. Biol. Radioecol. , vol.47 , pp. 302-306
    • Yang, H.1    Anzenberg, V.2    Held, K.D.3
  • 95
    • 0242392025 scopus 로고    scopus 로고
    • Gap junctional intercellular communication and cellular response to heat stress
    • Hamada, N., Kodama, S., Suzuki, K. and Watanabe, M. (2003) Gap junctional intercellular communication and cellular response to heat stress. Carcinogenesis 24: 1723-1728.
    • (2003) Carcinogenesis , vol.24 , pp. 1723-1728
    • Hamada, N.1    Kodama, S.2    Suzuki, K.3    Watanabe, M.4
  • 96
    • 0035468359 scopus 로고    scopus 로고
    • Medium-mediated bystander effects on HSG cells co-cultivated with cells irradiated by X-rays or a 290 MeV/u carbon beam
    • Shao, C., Aoki, M. and Furusawa, Y. (2001) Medium-mediated bystander effects on HSG cells co-cultivated with cells irradiated by X-rays or a 290 MeV/u carbon beam. J. Radiat. Res. 42: 305-316.
    • (2001) J. Radiat. Res. , vol.42 , pp. 305-316
    • Shao, C.1    Aoki, M.2    Furusawa, Y.3
  • 97
    • 0036736438 scopus 로고    scopus 로고
    • Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells
    • Shao, C., Furusawa, Y., Aoki, M., Matsumoto, H. and Ando, K. (2002) Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells. Int. J. Radiat. Biol. 78: 837-844.
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 837-844
    • Shao, C.1    Furusawa, Y.2    Aoki, M.3    Matsumoto, H.4    Ando, K.5
  • 98
    • 0344303533 scopus 로고    scopus 로고
    • Bystander effect on cell growth stimulation in neoplastic HSGc cells induced by heavy-ion irradiation
    • Shao, C., Aoki, M. and Furusawa, Y. (2003) Bystander effect on cell growth stimulation in neoplastic HSGc cells induced by heavy-ion irradiation. Radiat. Environ. Biophys. 42: 183-187.
    • (2003) Radiat. Environ. Biophys. , vol.42 , pp. 183-187
    • Shao, C.1    Aoki, M.2    Furusawa, Y.3
  • 99
    • 2542523939 scopus 로고    scopus 로고
    • Bystander effect in lymphoma cells vicinal to irradiated neoplastic epithelial cells: nitric oxide is involved
    • Shao, C., Aoki, M. and Furusawa, Y. (2004) Bystander effect in lymphoma cells vicinal to irradiated neoplastic epithelial cells: nitric oxide is involved. J. Radiat. Res. 45: 97-103.
    • (2004) J. Radiat. Res. , vol.45 , pp. 97-103
    • Shao, C.1    Aoki, M.2    Furusawa, Y.3
  • 100
    • 26844488765 scopus 로고    scopus 로고
    • Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathways
    • Proc. Natl. Acad. Sci. USA
    • Zhou, H., Ivanov, V. N., Gillespie, J., Geard, C. R., Amundson, S. A., Brenner, D. J., Yu, Z., Lieberman, H. B. and Hei, T. K. (2005) Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathways. Proc. Natl. Acad. Sci. USA 102: 14641-14646.
    • (2005) , vol.102 , pp. 14641-14646
    • Zhou, H.1    Ivanov, V.N.2    Gillespie, J.3    Geard, C.R.4    Amundson, S.A.5    Brenner, D.J.6    Yu, Z.7    Lieberman, H.B.8    Hei, T.K.9
  • 101
    • 33645153519 scopus 로고    scopus 로고
    • Radiation response of primary human skin fibroblasts and their bystander cells after exposure to counted particles at low and high LET
    • Frankenberg, D., Greif, K. D. and Giesen, U. (2006) Radiation response of primary human skin fibroblasts and their bystander cells after exposure to counted particles at low and high LET. Int. J. Radiat. Biol. 82: 59-67.
    • (2006) Int. J. Radiat. Biol. , vol.82 , pp. 59-67
    • Frankenberg, D.1    Greif, K.D.2    Giesen, U.3
  • 104
    • 33745829004 scopus 로고    scopus 로고
    • Radiation-induced bystander and other non-targeted effects: Novel intervention points in cancer therapy?
    • Mothersill, C. and Seymour, C. (2006) Radiation-induced bystander and other non-targeted effects: novel intervention points in cancer therapy? Curr. Cancer Drug Targets 6: 447-454.
    • (2006) Curr. Cancer Drug Targets , vol.6 , pp. 447-454
    • Mothersill, C.1    Seymour, C.2
  • 106
    • 41549115014 scopus 로고    scopus 로고
    • Quantitative analysis of isolated and clustered DNA damage induced by γ-rays, carbon ion beams, and iron ion beams
    • Terato, H., Tanaka, R., Nakaarai, Y., Nohara, T., Doi, Y., Iwai, S., Hirayama, R., Furusawa, Y. and Ide, H. (2008) Quantitative analysis of isolated and clustered DNA damage induced by γ-rays, carbon ion beams, and iron ion beams. J. Radiat. Res. 49: 133-146.
    • (2008) J. Radiat. Res. , vol.49 , pp. 133-146
    • Terato, H.1    Tanaka, R.2    Nakaarai, Y.3    Nohara, T.4    Doi, Y.5    Iwai, S.6    Hirayama, R.7    Furusawa, Y.8    Ide, H.9
  • 107
    • 33744825455 scopus 로고    scopus 로고
    • Contribution of indirect action to radiation-induced mammalian cell inactivation: dependence on photon energy and heavy-ion LET
    • Ito, A., Nakano, H., Kusano, Y., Hirayama, R., Furusawa, Y., Murayama, C., Mori, T., Katsumura, Y. and Shinohara, K. (2006) Contribution of indirect action to radiation-induced mammalian cell inactivation: dependence on photon energy and heavy-ion LET. Radiat. Res. 165: 703-712.
    • (2006) Radiat. Res. , vol.165 , pp. 703-712
    • Ito, A.1    Nakano, H.2    Kusano, Y.3    Hirayama, R.4    Furusawa, Y.5    Murayama, C.6    Mori, T.7    Katsumura, Y.8    Shinohara, K.9
  • 108
    • 62549140880 scopus 로고    scopus 로고
    • A LET-dependent decrease in the apoptotic response of normal human fibroblast cultures to isosurvival doses of γ-rays and energetic heavy ions
    • Hamada, N., Ni, M., Funayama, T., Sakashita, T., Sora, S., Nakano, T. and Kobayashi, Y. (2008) A LET-dependent decrease in the apoptotic response of normal human fibroblast cultures to isosurvival doses of γ-rays and energetic heavy ions. Biol. Sci. Space 22: 41-45.
    • (2008) Biol. Sci. Space , vol.22 , pp. 41-45
    • Hamada, N.1    Ni, M.2    Funayama, T.3    Sakashita, T.4    Sora, S.5    Nakano, T.6    Kobayashi, Y.7
  • 109
    • 25444448208 scopus 로고    scopus 로고
    • Reduction in life span of normal human fibroblasts exposed to very low-dose-rate charged particles
    • Suzuki, M., Tsuruoka, C., Uchihori, Y., Ebisawa, S., Yasuda, H. and Fujitaka, K. (2005) Reduction in life span of normal human fibroblasts exposed to very low-dose-rate charged particles. Radiat. Res. 164: 505-508.
    • (2005) Radiat. Res. , vol.164 , pp. 505-508
    • Suzuki, M.1    Tsuruoka, C.2    Uchihori, Y.3    Ebisawa, S.4    Yasuda, H.5    Fujitaka, K.6
  • 110
    • 34249803588 scopus 로고    scopus 로고
    • Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells
    • Okada, M., Okabe, A., Uchihori, Y., Kitamura, H., Sekine, E., Ebisawa, S., Suzuki, M. and Okayasu, R. (2007) Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells. Br. J. Cancer 96: 1707-1710.
    • (2007) Br. J. Cancer , vol.96 , pp. 1707-1710
    • Okada, M.1    Okabe, A.2    Uchihori, Y.3    Kitamura, H.4    Sekine, E.5    Ebisawa, S.6    Suzuki, M.7    Okayasu, R.8
  • 112
    • 44849136602 scopus 로고    scopus 로고
    • Proliferation and cell death of human glioblastoma cells after carbon-ion beam exposure: morphologic and morphometric analyses
    • Oishi, T., Sasaki, A., Hamada, N., Ishiuchi, S., Funayama, T., Sakashita, T., Kobayashi, Y., Nakano, T. and Nakazato, Y. (2008) Proliferation and cell death of human glioblastoma cells after carbon-ion beam exposure: morphologic and morphometric analyses. Neuropathology 28: 408-416.
    • (2008) Neuropathology , vol.28 , pp. 408-416
    • Oishi, T.1    Sasaki, A.2    Hamada, N.3    Ishiuchi, S.4    Funayama, T.5    Sakashita, T.6    Kobayashi, Y.7    Nakano, T.8    Nakazato, Y.9
  • 114
    • 19444387066 scopus 로고    scopus 로고
    • LET and ion species dependence for cell killing in normal human skin fibroblasts
    • Tsuruoka, C., Suzuki, M., Kanai, T. and Fujitaka, K. (2005) LET and ion species dependence for cell killing in normal human skin fibroblasts. Radiat. Res. 163: 494-500.
    • (2005) Radiat. Res. , vol.163 , pp. 494-500
    • Tsuruoka, C.1    Suzuki, M.2    Kanai, T.3    Fujitaka, K.4
  • 115
    • 31644439700 scopus 로고    scopus 로고
    • Cellular and molecular effects for mutation induction in normal human cells irradiated with accelerated neon ions
    • Suzuki, M., Tsuruoka, C., Kanai, T., Kato, T., Yatagai, F. and Watanabe, M. (2006) Cellular and molecular effects for mutation induction in normal human cells irradiated with accelerated neon ions. Mutat. Res. 594: 86-92.
    • (2006) Mutat. Res. , vol.594 , pp. 86-92
    • Suzuki, M.1    Tsuruoka, C.2    Kanai, T.3    Kato, T.4    Yatagai, F.5    Watanabe, M.6
  • 116
    • 49249100373 scopus 로고    scopus 로고
    • The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts
    • Tsuruoka, C., Suzuki, M., Hande, M. P., Furusawa, Y., Anzai, K. and Okayasu, R. (2008) The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts. Radiat. Res. 170: 163-171.
    • (2008) Radiat. Res. , vol.170 , pp. 163-171
    • Tsuruoka, C.1    Suzuki, M.2    Hande, M.P.3    Furusawa, Y.4    Anzai, K.5    Okayasu, R.6
  • 118
    • 40449084465 scopus 로고    scopus 로고
    • Modulatory effect of ionizing radiation on food-NaCl associative learning: the role of γ subunit of G protein in Caenorhabditis elegans
    • Sakashita, T., Hamada, N., Ikeda, D. D., Yanase, S., Suzuki, M., Ishii, N. and Kobayashi, Y. (2008) Modulatory effect of ionizing radiation on food-NaCl associative learning: the role of γ subunit of G protein in Caenorhabditis elegans. FASEB J. 22: 713-720.
    • (2008) FASEB J. , vol.22 , pp. 713-720
    • Sakashita, T.1    Hamada, N.2    Ikeda, D.D.3    Yanase, S.4    Suzuki, M.5    Ishii, N.6    Kobayashi, Y.7
  • 119
    • 44349106476 scopus 로고    scopus 로고
    • Locomotion - learning behavior relationship in Caenorhabditis elegans following γ-ray irradiation
    • Sakashita, T., Hamada, N., Ikeda, D. D., Suzuki, M., Yanase, S., Ishii, N. and Kobayashi, Y. (2008) Locomotion - learning behavior relationship in Caenorhabditis elegans following γ-ray irradiation. J. Radiat. Res. 49: 285-291.
    • (2008) J. Radiat. Res. , vol.49 , pp. 285-291
    • Sakashita, T.1    Hamada, N.2    Ikeda, D.D.3    Suzuki, M.4    Yanase, S.5    Ishii, N.6    Kobayashi, Y.7
  • 120
    • 35548957871 scopus 로고    scopus 로고
    • Tardigrades as a potential model organism in space research
    • Jonsson, K. I. (2007) Tardigrades as a potential model organism in space research. Astrobiology 7: 757-766.
    • (2007) Astrobiology , vol.7 , pp. 757-766
    • Jonsson, K.I.1


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