Different Mechanisms of Cell Death in Radiosensitive and Radioresistant P53 Mutated Head and Neck Squamous Cell Carcinoma Cell Lines Exposed to Carbon Ions and X-Rays

International Journal of Radiation Oncology Biology Physics

Volumn 74, Issue 1, 2009, Pages 200-209

  Maalouf, Mira ^a   Alphonse, Gersende ^a,b   Colliaux, Anthony ^a,c   Beuve, Michaël ^a,c   Trajkovic Bodennec, Selena ^a   Battiston Montagne, Priscillia ^a   Testard, Isabelle ^d   Chapet, Olivier ^b   Bajard, Marcel ^a,c   Taucher Scholz, Gisela ^e   Fournier, Claudia ^e   Rodriguez Lafrasse, Claire ^a,b  

^a UNIVERSITÉ LYON 1   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c CENTRE DE CALCUL DE L INSTITUT NATIONAL DE PHYSIQUE NUCLEAIRE ET DE PHYSIQUE DES PARTICULES   (France)

^d GANIL   (France)

^e GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

Author keywords

Apoptosis; Carbon ion irradiation; High and low LET irradiation; HNSCC; Mitotic catastrophe

Indexed keywords

CARBON; CELL CULTURE; CELL DEATH; CHEMICAL ACTIVATION; DISASTERS; ENERGY TRANSFER; ION BOMBARDMENT; IONS; PATIENT MONITORING; PATIENT TREATMENT; RADIATION;

DIFFERENT MECHANISMS; HEAD-AND-NECK SQUAMOUS CELL CARCINOMA; HIGH LINEAR ENERGY TRANSFERS; HNSCC; LOCOREGIONAL RECURRENCE; METHODS AND MATERIALS; MITOTIC CATASTROPHE; MULTINUCLEATED CELLS;

X RAYS;

ALPHA TUBULIN; BETA GALACTOSIDASE; CASPASE 2; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN P21; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CANCER RECURRENCE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL SUBPOPULATION; CLONOGENESIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; ION THERAPY; LINEAR ENERGY TRANSFER; LOCAL THERAPY; MITOSIS; MULTINUCLEAR CELL; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIVITY; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME; X RAY;

EID: 64049087395     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.01.012     Document Type: Article

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