-
1
-
-
33845700514
-
Riboswitches as antibacterial drug targets
-
DOI 10.1038/nbt1268, PII NBT1268
-
Blount, K. F. & Breaker, R. R. Riboswitches as antibacterial drug targets. Nat Biotechnol. 24, 1558-1564 (2006). (Pubitemid 44967480)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.12
, pp. 1558-1564
-
-
Blount, K.F.1
Breaker, R.R.2
-
2
-
-
33749516448
-
MicroRNAs and chromosomal abnormalities in cancer cells
-
DOI 10.1038/sj.onc.1209910, PII 1209910
-
Calin, G. A. & Croce, C. M. MicroRNAs and chromosomal abnormalities in cancer cells. Oncogene 25, 6202-6210 (2006). (Pubitemid 44527851)
-
(2006)
Oncogene
, vol.25
, Issue.46
, pp. 6202-6210
-
-
Calin, G.A.1
Croce, C.M.2
-
3
-
-
28144441826
-
The bacterial ribosome as a target for antibiotics
-
DOI 10.1038/nrmicro1265, PII N1265
-
Poehlsgaard, J. & Douthwaite, S. The bacterial ribosome as a target for antibiotics. Nat Rev. Microbiol. 3, 870-881 (2005). (Pubitemid 41693182)
-
(2005)
Nature Reviews Microbiology
, vol.3
, Issue.11
, pp. 870-881
-
-
Poehlsgaard, J.1
Douthwaite, S.2
-
5
-
-
0032500736
-
Controlling gene expression in living cells through small molecule-RNA interactions
-
DOI 10.1126/science.282.5387.296
-
Werstuck, G. & Green, M. R. Controlling gene expression in living cells through small molecule-RNA interactions. Science 282, 296-298 (1998). (Pubitemid 28487202)
-
(1998)
Science
, vol.282
, Issue.5387
, pp. 296-298
-
-
Werstuck, G.1
Green, M.R.2
-
6
-
-
43149103943
-
Targeting RNA with small molecules
-
DOI 10.1021/cr0681546
-
Tomas, J. R. & Hergenrother, P. J. Targeting RNA with small molecules. Chem. Rev. 108, 1171-1224 (2008). (Pubitemid 351638813)
-
(2008)
Chemical Reviews
, vol.108
, Issue.4
, pp. 1171-1224
-
-
Thomas, J.R.1
Hergenrother, P.J.2
-
7
-
-
84856134636
-
Recent advances in developing small molecules targeting RNA
-
Guan, L. & Disney, M. D. Recent advances in developing small molecules targeting RNA. ACS Chem. Biol. 7, 73-86 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 73-86
-
-
Guan, L.1
Disney, M.D.2
-
8
-
-
0035070585
-
Immobilized RNA switches for the analysis of complex chemical and biological mixtures
-
DOI 10.1038/86723
-
Seetharaman, S., Zivarts, M., Sudarsan, N. & Breaker, R. R. Immobilized RNA switches for the analysis of complex chemical and biological mixtures. Nat Biotechnol. 19, 336-341 (2001). (Pubitemid 32275342)
-
(2001)
Nature Biotechnology
, vol.19
, Issue.4
, pp. 336-341
-
-
Seetharaman, S.1
Zivarts, M.2
Sudarsan, N.3
Breaker, R.R.4
-
9
-
-
0001183268
-
A structural basis for RNA-ligand interactions
-
Chow, C. S. & Bogdan, F. M. A structural basis for RNA-ligand interactions. Chem. Rev. 97, 1489-1514 (1997).
-
(1997)
Chem. Rev.
, vol.97
, pp. 1489-1514
-
-
Chow, C.S.1
Bogdan, F.M.2
-
10
-
-
0034783659
-
Targeting RNA with Small-molecule drugs: Therapeutic promise and chemical challenges
-
DOI 10.1021/ar000118k
-
Gallego, J. & Varani, G. Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges. Acc. Chem. Res. 34, 836-843 (2001). (Pubitemid 32999608)
-
(2001)
Accounts of Chemical Research
, vol.34
, Issue.10
, pp. 836-843
-
-
Gallego, J.1
Varani, G.2
-
11
-
-
0028362969
-
In vitro evolution of nucleic acids
-
DOI 10.1016/S0959-440X(94)90100-7
-
Joyce, G. F. In vitro evolution of nucleic acids. Curr. Opin. Struct. Biol. 4, 331-336 (1994). (Pubitemid 24195847)
-
(1994)
Current Opinion in Structural Biology
, vol.4
, Issue.3
, pp. 331-336
-
-
Joyce, G.F.1
-
12
-
-
0028191743
-
All you wanted to know about SELEX
-
Klug, S. J. & Famulok, M. All you wanted to know about SELEX. Mol. Biol. Rep. 20, 97-107 (1994).
-
(1994)
Mol. Biol. Rep.
, vol.20
, pp. 97-107
-
-
Klug, S.J.1
Famulok, M.2
-
13
-
-
0041629318
-
Preferred RNA binding sites for a threading intercalator revealed by in vitro evolution
-
DOI 10.1016/S1074-5521(03)00147-9
-
Carlson, C. B., Vuyisich, M., Gooch, B. D. & Beal, P. A. Preferred RNA binding sites for a threading intercalator revealed by in vitro evolution. Chem. Biol. 10, 663-672 (2003). (Pubitemid 36940943)
-
(2003)
Chemistry and Biology
, vol.10
, Issue.7
, pp. 663-672
-
-
Carlson, C.B.1
Vuyisich, M.2
Gooch, B.D.3
Beal, P.A.4
-
14
-
-
0030252953
-
Screening chemical libraries for nucleic-acid-binding drugs by in vitro selection: A test case with lividomycin
-
Lato, S. M. & Ellington, A. D. Screening chemical libraries for nucleic acid-binding drugs by in vitro selection: a test case with lividomycin. Mol. Divers. 2, 103-110 (1996). (Pubitemid 126817072)
-
(1996)
Molecular Diversity
, vol.2
, Issue.1-2
, pp. 103-110
-
-
Lato, S.M.1
Ellington, A.D.2
-
15
-
-
0037448895
-
Discovery of aminoglycoside mimetics by NMR-based screening of Escherichia coli A-site RNA
-
DOI 10.1021/ja021354o
-
Yu, L. et al. Discovery of aminoglycoside mimetics by NMR-based screening of Escherichia coli A-site RNA. J. Am. Chem. Soc. 125, 4444-4450 (2003). (Pubitemid 36418691)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.15
, pp. 4444-4450
-
-
Yu, L.1
Oost, T.K.2
Schkeryantz, J.M.3
Yang, J.4
Janowick, D.5
Fesik, S.W.6
-
16
-
-
0033621114
-
Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry
-
DOI 10.1073/pnas.96.18.10129
-
Grifey, R. H., Hofstadler, S. A., Sannes-Lowery K. A., Ecker, D. J. & Crooke, S. T. Determinants of aminoglycoside-binding specifcity for rRNA by using mass spectrometry Proc. Natl Acad. Sci. USA 96, 10129-10133 (1999). (Pubitemid 29422524)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.18
, pp. 10129-10133
-
-
Griffey, R.H.1
Hofstadler, S.A.2
Sannes-Lowery, K.A.3
Ecker, D.J.4
Crooke, S.T.5
-
17
-
-
0037194620
-
SAR by MS: A ligand based technique for drug lead discovery against structured RNA targets
-
DOI 10.1021/jm0255466
-
Swayze, E. E. et al. SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets. J. Med. Chem. 45, 3816-3819 (2002). (Pubitemid 35024285)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.18
, pp. 3816-3819
-
-
Swayze, E.E.1
Jefferson, E.A.2
Sannes-Lowery, K.A.3
Blyn, L.B.4
Risen, L.M.5
Arakawa, S.6
Osgood, S.A.7
Hofstadler, S.A.8
Griffey, R.H.9
-
18
-
-
0030444867
-
Inhibition of self-splicing group i intron RNA: High-throughput screening assays
-
Mei, H. Y. et al. Inhibition of self-splicing group I intron RNA: high-throughput screening assays. Nucleic Acids Res. 24, 5051-5053 (1996).
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 5051-5053
-
-
Mei, H.Y.1
-
19
-
-
0031005114
-
Discovery of selective, small-molecule inhibitors of RNA complexes-I. The Tat protein/TAR RNA complexes required for HIV-1 transcription
-
Mei, H. Y. et al. Discovery of selective, small-molecule inhibitors of RNA complexes-I. The Tat protein/TAR RNA complexes required for HIV-1 transcription. Bioorg. Med. Chem. 5, 1173-1184 (1997).
-
(1997)
Bioorg. Med. Chem.
, vol.5
, pp. 1173-1184
-
-
Mei, H.Y.1
-
20
-
-
37349030751
-
A small molecule microarray platform to select RNA internal loop - Ligand interactions
-
DOI 10.1021/cb700174r
-
Childs-Disney J. L., Wu, M., Pushechnikov, A., Aminova, O. & Disney M. D. A small molecule microarray platform to select RNA internal loop-ligand interactions. ACS Chem. Biol. 2, 745-754 (2007). (Pubitemid 350285910)
-
(2007)
ACS Chemical Biology
, vol.2
, Issue.11
, pp. 745-754
-
-
Childs-Disney, J.L.1
Wu, M.2
Pushechnikov, A.3
Aminova, O.4
Disney, M.D.5
-
21
-
-
50249089546
-
Two-dimensional combinatorial screening identifes specifc aminoglycoside-RNA internal loop partners
-
Disney M. D. et al. Two-dimensional combinatorial screening identifes specifc aminoglycoside-RNA internal loop partners. J. Am. Chem. Soc. 130, 11185-11194 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 11185-11194
-
-
Disney, M.D.1
-
22
-
-
84863268614
-
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database & chemical similarity searching
-
Parkesh, R. et al. Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database & chemical similarity searching. J. Am. Chem. Soc. 134, 4731-4742 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 4731-4742
-
-
Parkesh, R.1
-
23
-
-
84863385282
-
Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts
-
Kumar, A. et al. Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts. ACS Chem. Biol. 7, 496-505 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 496-505
-
-
Kumar, A.1
-
24
-
-
67650506996
-
Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: Application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3
-
Pushechnikov, A. et al. Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3. J. Am. Chem. Soc. 131, 9767-9779 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 9767-9779
-
-
Pushechnikov, A.1
-
25
-
-
65749087933
-
Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2
-
Lee, M. M., Pushechnikov, A. & Disney M. D. Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2. ACS Chem. Biol. 4, 345-355 (2009).
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 345-355
-
-
Lee, M.M.1
Pushechnikov, A.2
Disney, M.D.3
-
26
-
-
1642576322
-
A fuorescent intercalator displacement assay for establishing DNA binding selectivity and afnity
-
Tse, W. C. & Boger, D. L. A fuorescent intercalator displacement assay for establishing DNA binding selectivity and afnity. Acc. Chem. Res. 37, 61-69 (2004).
-
(2004)
Acc. Chem. Res.
, vol.37
, pp. 61-69
-
-
Tse, W.C.1
Boger, D.L.2
-
27
-
-
0034833710
-
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity
-
DOI 10.1021/ja010041a
-
Boger, D. L., Fink, B. E., Brunette, S. R., Tse, W. C. & Hedrick, M. P. A simple, high-resolution method for establishing DNA binding afnity and sequence selectivity J. Am. Chem. Soc. 123, 5878-5891 (2001). (Pubitemid 32888456)
-
(2001)
Journal of the American Chemical Society
, vol.123
, Issue.25
, pp. 5878-5891
-
-
Boger, D.L.1
Fink, B.E.2
Brunette, S.R.3
Tse, W.C.4
Hedrick, M.P.5
-
28
-
-
78149411111
-
A modifed fuorescent intercalator displacement assay for RNA ligand discovery Anal
-
Asare-Okai, P. N. & Chow, C. S. A modifed fuorescent intercalator displacement assay for RNA ligand discovery Anal. Biochem. 408, 269-276 (2011).
-
(2011)
Biochem.
, vol.408
, pp. 269-276
-
-
Asare-Okai, P.N.1
Chow, C.S.2
-
29
-
-
52949100972
-
Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay
-
Krishnamurthy, M., Schirle, N. T. & Beal, P. A. Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay. Bioorg. Med. Chem. 16, 8914-8921 (2008).
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 8914-8921
-
-
Krishnamurthy, M.1
Schirle, N.T.2
Beal, P.A.3
-
30
-
-
77949806090
-
Fluorescent indicator displacement assay for ligand-RNA interactions
-
Zhang, J., Umemoto, S. & Nakatani, K. Fluorescent indicator displacement assay for ligand-RNA interactions. J. Am. Chem. Soc. 132, 3660-3661 (2010).
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 3660-3661
-
-
Zhang, J.1
Umemoto, S.2
Nakatani, K.3
-
31
-
-
2442626706
-
Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure
-
DOI 10.1073/pnas.0401799101
-
Mathews, D. H. et al. Incorporating chemical modifcation constraints into a dynamic programming algorithm for prediction of RNA secondary structure. Proc. Natl Acad. Sci. USA 101, 7287-7292 (2004). (Pubitemid 38638025)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.19
, pp. 7287-7292
-
-
Mathews, D.H.1
Disney, M.D.2
Childs, J.L.3
Schroeder, S.J.4
Zuker, M.5
Turner, D.H.6
-
32
-
-
58549109608
-
Accurate SHAPE-directed RNA structure determination
-
Deigan, K. E., Li, T. W., Mathews, D. H. & Weeks, K. M. Accurate SHAPE-directed RNA structure determination. Proc. Natl Acad. Sci. USA 106, 97-102 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 97-102
-
-
Deigan, K.E.1
Li, T.W.2
Mathews, D.H.3
Weeks, K.M.4
-
33
-
-
68449092202
-
Architecture and secondary structure of an entire HIV-1 RNA genome
-
Watts, J. M. et al. Architecture and secondary structure of an entire HIV-1 RNA genome. Nature 460, 711-716 (2009).
-
(2009)
Nature
, vol.460
, pp. 711-716
-
-
Watts, J.M.1
-
34
-
-
10844284608
-
Hoechst 33258 selectively inhibits group I intron self-splicing by affecting RNA folding
-
DOI 10.1002/cbic.200400159
-
Disney, M. D., Childs, J. L. & Turner, D. H. Hoechst 33258 selectively inhibits group I intron self-splicing by afecting RNA folding. Chembiochem 5, 1647-1652 (2004). (Pubitemid 39664674)
-
(2004)
ChemBioChem
, vol.5
, Issue.12
, pp. 1647-1652
-
-
Disney, M.D.1
Childs, J.L.2
Turner, D.H.3
-
35
-
-
0036639785
-
Pentamidine inhibits catalytic activity of group I intron Ca.LSU by altering RNA folding
-
Zhang, Y., Li, Z., Pilch, D. S. & Leibowitz, M. J. Pentamidine inhibits catalytic activity of group I intron Ca.LSU by altering RNA folding. Nucleic Acids Res. 30, 2961-2971 (2002). (Pubitemid 34778156)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.13
, pp. 2961-2971
-
-
Zhang, Y.1
Li, Z.2
Pilch, D.S.3
Leibowitz, M.J.4
-
36
-
-
28544443385
-
SAR by MS: Discovery of a new class of RNA-binding small molecules for the hepatitis C virus: Internal ribosome entry site IIA subdomain
-
DOI 10.1021/jm050815o
-
Seth, P. P. et al. SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain. J. Med. Chem. 48, 7099-7102 (2005). (Pubitemid 41743623)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.23
, pp. 7099-7102
-
-
Seth, P.P.1
Miyaji, A.2
Jefferson, E.A.3
Sannes-Lowery, K.A.4
Osgood, S.A.5
Propp, S.S.6
Ranken, R.7
Massire, C.8
Sampath, R.9
Ecker, D.J.10
Swayze, E.E.11
Griffey, R.H.12
-
37
-
-
1642534336
-
Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry
-
DOI 10.1016/j.bmcl.2003.11.031
-
He, Y. et al. Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry. Bioorg. Med. Chem. Lett. 14, 695-699 (2004). (Pubitemid 38114855)
-
(2004)
Bioorganic and Medicinal Chemistry Letters
, vol.14
, Issue.3
, pp. 695-699
-
-
He, Y.1
Yang, J.2
Wu, B.3
Robinson, D.4
Sprankle, K.5
Kung, P.-P.6
Lowery, K.7
Mohan, V.8
Hofstadler, S.9
Swayze, E.E.10
Griffey, R.11
-
38
-
-
33644876210
-
DrugBank: A comprehensive resource for in silico drug discovery and exploration
-
Wishart, D. S. et al. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res. 34, D668-672 (2006).
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Wishart, D.S.1
-
39
-
-
0034658197
-
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA
-
Cho, J. & Rando, R. R. Specifc binding of Hoechst 33258 to site 1 thymidylate synthase mRNA. Nucleic Acids Res. 28, 2158-2163 (2000). (Pubitemid 30255539)
-
(2000)
Nucleic Acids Research
, vol.28
, Issue.10
, pp. 2158-2163
-
-
Cho, J.1
Rando, R.R.2
-
40
-
-
0028010390
-
Inhibition of in vitro splicing of a group I intron of Pneumocystis carinii
-
Liu, Y., Tidwell, R. R. & Leibowitz, M. J. Inhibition of in vitro splicing of a group I intron of Pneumocystis carinii. J. Eukaryot. Microbiol. 41, 31-38 (1994). (Pubitemid 2058489)
-
(1994)
Journal of Eukaryotic Microbiology
, vol.41
, Issue.1
, pp. 31-38
-
-
Liu Yong1
Tidwell, R.R.2
Leibowitz, M.J.3
-
41
-
-
0034021518
-
Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition
-
DOI 10.1128/AAC.44.4.958-966.2000
-
Miletti, K. E. & Leibowitz, M. J. Pentamidine inhibition of group I intron splicing in Candida albicans correlates with growth inhibition. Antimicrob. Agents Chemother. 44, 958-966 (2000). (Pubitemid 30165276)
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, Issue.4
, pp. 958-966
-
-
Miletti, K.E.1
Leibowitz, M.J.2
-
42
-
-
73249132978
-
Pentamidine reverses the splicing defects associated with myotonic dystrophy
-
Warf, M. B., Nakamori, M., Matthys, C. M., Tornton, C. A. & Berglund, J. A. Pentamidine reverses the splicing defects associated with myotonic dystrophy Proc. Natl Acad. Sci. USA 106, 18551-18556 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 18551-18556
-
-
Warf, M.B.1
Nakamori, M.2
Matthys, C.M.3
Tornton, C.A.4
Berglund, J.A.5
-
43
-
-
0033913732
-
Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae
-
DOI 10.1017/S1355838200991726
-
Zhang, Y., Bell, A., Perlman, P. S. & Leibowitz, M. J. Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. RNA 6, 937-951 (2000). (Pubitemid 30471132)
-
(2000)
RNA
, vol.6
, Issue.7
, pp. 937-951
-
-
Zhang, Y.1
Bell, A.2
Perlman, P.S.3
Leibowitz, M.J.4
-
44
-
-
3943057542
-
Characterization of an inexpensive, nontoxic, and highly sensitive microarray substrate
-
294-296
-
Dufva, M., Petronis, S., Jensen, L. B., Krag, C. & Christensen, C. B. Characterization of an inexpensive, nontoxic, and highly sensitive microarray substrate. Biotechniques 37, 286-292 294, 296 (2004).
-
(2004)
Biotechniques
, vol.37
, pp. 286-292
-
-
Dufva, M.1
Petronis, S.2
Jensen, L.B.3
Krag, C.4
Christensen, C.B.5
-
45
-
-
0034658890
-
Preparation of DNA and protein microarrays on glass slides coated with an agarose flm
-
Afanassiev, V., Hanemann, V. & Wolf, S. Preparation of DNA and protein microarrays on glass slides coated with an agarose flm. Nucleic Acids Res. 28, E66 (2000).
-
(2000)
Nucleic Acids Res.
, vol.28
-
-
Afanassiev, V.1
Hanemann, V.2
Wolf, S.3
-
46
-
-
20444388307
-
Small molecule shape-fngerprints
-
Haigh, J. A., Pickup, B. T., Grant, J. A. & Nicholls, A. Small molecule shape-fngerprints. J. Chem. Inf. Model. 45, 673-684 (2005).
-
(2005)
J. Chem. Inf. Model.
, vol.45
, pp. 673-684
-
-
Haigh, J.A.1
Pickup, B.T.2
Grant, J.A.3
Nicholls, A.4
-
47
-
-
60549099994
-
Detection and assignment of common scafolds in project databases of lead molecules
-
Clark, A. M. & Labute, P. Detection and assignment of common scafolds in project databases of lead molecules. J. Med. Chem. 52, 469-483 (2009).
-
(2009)
J. Med. Chem.
, vol.52
, pp. 469-483
-
-
Clark, A.M.1
Labute, P.2
-
48
-
-
77749255506
-
Two-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: Defning privileged asymmetric internal loops that bind aminoglycosides
-
Tran, T. & Disney, M. D. Two-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: defning privileged asymmetric internal loops that bind aminoglycosides. Biochemistry 49, 1833-1842 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 1833-1842
-
-
Tran, T.1
Disney, M.D.2
-
49
-
-
77952658021
-
Structure-activity relationships through sequencing (StARTS) defnes optimal and suboptimal RNA motif targets for small molecules
-
Velagapudi, S. P, Seedhouse, S. J. & Disney, M. D. Structure-activity relationships through sequencing (StARTS) defnes optimal and suboptimal RNA motif targets for small molecules. Angew. Chem. Int. Ed. 49, 3816-3818 (2010).
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 3816-3818
-
-
Velagapudi, S.P.1
Seedhouse, S.J.2
Disney, M.D.3
-
50
-
-
73049117567
-
Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efciently identify aminoglycoside-RNA hairpin loop interactions
-
Paul, D. J., Seedhouse, S. J. & Disney, M. D. Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efciently identify aminoglycoside-RNA hairpin loop interactions. Nucleic Acids Res. 37, 5894-5907 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5894-5907
-
-
Paul, D.J.1
Seedhouse, S.J.2
Disney, M.D.3
-
51
-
-
79959902464
-
Defning the RNA internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis
-
Velagapudi, S. P., Seedhouse, S. J., French, J. & Disney, M. D. Defning the RNA internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis. J. Am. Chem. Soc. 133, 10111-10118 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 10111-10118
-
-
Velagapudi, S.P.1
Seedhouse, S.J.2
French, J.3
Disney, M.D.4
-
52
-
-
75449088319
-
The Privileged Chemical Space Predictor (pcsp): A computer program that identifes privileged chemical space from screens of modularly assembled chemical libraries
-
Seedhouse, S. J., Labuda, L. P. & Disney, M. D. The Privileged Chemical Space Predictor (pcsp): A computer program that identifes privileged chemical space from screens of modularly assembled chemical libraries. Bioorg. Med. Chem. Lett. 20, 1338-1343 (2010).
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 1338-1343
-
-
Seedhouse, S.J.1
Labuda, L.P.2
Disney, M.D.3
-
53
-
-
34250367088
-
Using selection to identify and chemical microarray to study the RNA internal loops recognized by 6′-N-acylated kanamycin A
-
DOI 10.1002/cbic.200600569
-
Disney, M. D. & Childs-Disney, J. L. Using selection to identify and chemical microarray to study the RNA internal loops recognized by 6'-N-acylated kanamycin A. Chembiochem 8, 649-656 (2007). (Pubitemid 47194857)
-
(2007)
ChemBioChem
, vol.8
, Issue.6
, pp. 649-656
-
-
Disney, M.D.1
Childs-Disney, J.L.2
-
54
-
-
57049107410
-
Two-dimensional combinatorial screening identifes specifc 6'-acylated kanamycin A-and 6'-acylated neamine-RNA hairpin interactions
-
Aminova, O., Paul, D. J., Childs-Disney, J. L. & Disney, M. D. Two-dimensional combinatorial screening identifes specifc 6'-acylated kanamycin A-and 6'-acylated neamine-RNA hairpin interactions. Biochemistry 47, 12670-12679 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 12670-12679
-
-
Aminova, O.1
Paul, D.J.2
Childs-Disney, J.L.3
Disney, M.D.4
-
55
-
-
38649130485
-
A simple ligation-based method to increase the information density in sequencing reactions used to deconvolute nucleic acid selections
-
DOI 10.1261/rna.576908
-
Childs-Disney, J. L. & Disney, M. D. A simple ligation-based method to increase the information density in sequencing reactions used to deconvolute nucleic acid selections. RNA 14, 390-394 (2008). (Pubitemid 351171598)
-
(2008)
RNA
, vol.14
, Issue.2
, pp. 390-394
-
-
Childs-Disney, J.L.1
Disney, M.D.2
-
56
-
-
65649087836
-
Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group i intron
-
Labuda, L. P, Pushechnikov, A. & Disney, M. D. Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intron. ACS Chem. Biol. 4, 299-307 (2009).
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 299-307
-
-
Labuda, L.P.1
Pushechnikov, A.2
Disney, M.D.3
-
57
-
-
0032506045
-
Thermodynamic analysis of an RNA combinatorial library contained in a short hairpin
-
DOI 10.1021/bi981732v
-
Bevilacqua, J. M. & Bevilacqua, P. C. Termodynamic analysis of an RNA combinatorial library contained in a short hairpin. Biochemistry 37, 15877-15884 (1998). (Pubitemid 28524759)
-
(1998)
Biochemistry
, vol.37
, Issue.45
, pp. 15877-15884
-
-
Bevilacqua, J.M.1
Bevilacqua, P.C.2
-
58
-
-
79851497250
-
Molecular recognition of 6'-N-5-hexynoate kanamycin A and RNA 1x1 internal loops containing CA mismatches
-
Tran, T. & Disney, M. D. Molecular recognition of 6'-N-5-hexynoate kanamycin A and RNA 1x1 internal loops containing CA mismatches. Biochemistry 50, 962-969 (2011).
-
(2011)
Biochemistry
, vol.50
, pp. 962-969
-
-
Tran, T.1
Disney, M.D.2
-
59
-
-
0029294539
-
Specifc binding of aminoglycoside antibiotics to RNA
-
Wang, Y & Rando, R. R. Specifc binding of aminoglycoside antibiotics to RNA. Chem. Biol. 2, 281-290 (1995).
-
(1995)
Chem. Biol.
, vol.2
, pp. 281-290
-
-
Wang, Y.1
Rando, R.R.2
|