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Volumn 32, Issue 21, 2012, Pages 4419-4431

Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor

Author keywords

[No Author keywords available]

Indexed keywords

ACID CERAMIDASE; CYCLIC AMP; SPHINGOLIPID;

EID: 84868711153     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00378-12     Document Type: Article
Times cited : (24)

References (82)
  • 1
    • 0031561126 scopus 로고    scopus 로고
    • Chromatin neutral sphingomyelinase and its role in hepatic regeneration
    • Albi E, Magni MP. 1997. Chromatin neutral sphingomyelinase and its role in hepatic regeneration. Biochem. Biophys. Res. Commun. 236: 29 -33.
    • (1997) Biochem. Biophys. Res. Commun. , vol.236 , pp. 29-33
    • Albi, E.1    Magni, M.P.2
  • 2
    • 0032701342 scopus 로고    scopus 로고
    • Sphingomyelin synthase in rat liver nuclear membrane and chromatin
    • Albi E, Magni MV. 1999. Sphingomyelin synthase in rat liver nuclear membrane and chromatin. FEBS Lett. 460:369 -372.
    • (1999) FEBS Lett , vol.460 , pp. 369-372
    • Albi, E.1    Magni, M.V.2
  • 3
    • 0029070822 scopus 로고
    • Purification, characterization, and biosynthesis of human acid ceramidase
    • Bernardo K, et al. 1995. Purification, characterization, and biosynthesis of human acid ceramidase. J. Biol. Chem. 270:11098 -11102.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11098-11102
    • Bernardo, K.1
  • 4
    • 84862884630 scopus 로고    scopus 로고
    • Direct modification and activation of a nuclear receptor-PIP2 complex by the inositol lipid kinase IPMK
    • doi:10.1126/scisignal.2003111
    • Blind RD, Suzawa M, Ingraham HA. 2012. Direct modification and activation of a nuclear receptor-PIP2 complex by the inositol lipid kinase IPMK. Sci. Signal. 5:ra44. doi:10.1126/scisignal.2003111.
    • (2012) Sci. Signal. , vol.5
    • Blind, R.D.1    Suzawa, M.2    Ingraham, H.A.3
  • 5
    • 0012441553 scopus 로고    scopus 로고
    • The nuclear receptor coactivators p300/CBP/ cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1
    • Børud B, et al. 2002. The nuclear receptor coactivators p300/CBP/ cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1. Mol. Endocrinol. 16:757-773.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 757-773
    • Børud, B.1
  • 6
    • 28044439874 scopus 로고    scopus 로고
    • SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increasedDNAbinding
    • Chen WY, Juan LJ, Chung BC. 2005. SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increasedDNAbinding. Mol. Cell. Biol. 25:10442-10453.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10442-10453
    • Chen, W.Y.1    Juan, L.J.2    Chung, B.C.3
  • 7
    • 4644354099 scopus 로고    scopus 로고
    • SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1)
    • Chen WY, Lee WC, Hsu NC, Huang F, Chung BC. 2004. SUMO modification of repression domains modulates function of nuclear receptor 5A1 (steroidogenic factor-1). J. Biol. Chem. 279:38730 -38735.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38730-38735
    • Chen, W.Y.1    Lee, W.C.2    Hsu, N.C.3    Huang, F.4    Chung, B.C.5
  • 8
    • 52049108218 scopus 로고    scopus 로고
    • Identification and characterization of a general nuclear translocation signal in signaling proteins
    • Chuderland D, Konson A, Seger R. 2008. Identification and characterization of a general nuclear translocation signal in signaling proteins. Mol. Cell 31:850-861.
    • (2008) Mol. Cell , vol.31 , pp. 850-861
    • Chuderland, D.1    Konson, A.2    Seger, R.3
  • 9
    • 0031895798 scopus 로고    scopus 로고
    • Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
    • Crawford PA, Dorn C, Sadovsky Y, Milbrandt J. 1998. Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Mol. Cell. Biol. 18:2949 -2956.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2949-2956
    • Crawford, P.A.1    Dorn, C.2    Sadovsky, Y.3    Milbrandt, J.4
  • 10
    • 0030866813 scopus 로고    scopus 로고
    • The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1
    • Crawford PA, Polish JA, Ganpule G, Sadovsky Y. 1997. The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1. Mol. Endocrinol. 11:1626 -1635.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1626-1635
    • Crawford, P.A.1    Polish, J.A.2    Ganpule, G.3    Sadovsky, Y.4
  • 11
    • 0037203316 scopus 로고    scopus 로고
    • Sphingosine in apoptosis signaling
    • Cuvillier O. 2002. Sphingosine in apoptosis signaling. Biochim. Biophys. Acta 1585:153-162.
    • (2002) Biochim. Biophys. Acta , vol.1585 , pp. 153-162
    • Cuvillier, O.1
  • 12
    • 33846707882 scopus 로고    scopus 로고
    • Coregulator exchange and sphingosine-sensitive cooperativity of steroidogenic factor-1, general control nonderepressed 5, p54, and p160 coactivators regulate cyclic adenosine 3', 5'-monophosphate-dependent cytochrome P450c17 transcription rate
    • Dammer EB, Leon A, Sewer MB. 2007. Coregulator exchange and sphingosine-sensitive cooperativity of steroidogenic factor-1, general control nonderepressed 5, p54, and p160 coactivators regulate cyclic adenosine 3',5'-monophosphate-dependent cytochrome P450c17 transcription rate. Mol. Endocrinol. 21:415- 438.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 415-438
    • Dammer, E.B.1    Leon, A.2    Sewer, M.B.3
  • 13
    • 0036787839 scopus 로고    scopus 로고
    • Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1
    • Desclozeaux M, Krylova IN, Horn F, Fletterick RJ, Ingraham HA. 2002. Phosphorylation and intramolecular stabilization of the ligand binding domain in the nuclear receptor steroidogenic factor 1. Mol. Cell. Biol. 22:7193-7203.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7193-7203
    • Desclozeaux, M.1    Krylova, I.N.2    Horn, F.3    Fletterick, R.J.4    Ingraham, H.A.5
  • 14
    • 33746639616 scopus 로고    scopus 로고
    • Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping
    • Dubbink HJ, et al. 2006. Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping. Mol. Endocrinol. 20:1742-1755.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1742-1755
    • Dubbink, H.J.1
  • 15
    • 0028940657 scopus 로고
    • Nuclear import of glycoconjugates is distinct from the classical NLS pathway
    • Duverger E, Pellerin-Mendes C, Mayer R, Roche AC, Monsigny M. 1995. Nuclear import of glycoconjugates is distinct from the classical NLS pathway. J. Cell Sci. 108(Part 4):1325-1332.
    • (1995) J. Cell Sci. , vol.108 , Issue.PART 4 , pp. 1325-1332
    • Duverger, E.1    Pellerin-Mendes, C.2    Mayer, R.3    Roche, A.C.4    Monsigny, M.5
  • 16
    • 34247554203 scopus 로고    scopus 로고
    • Acid ceramidase is a novel factor required for early embryo survival
    • Eliyahu E, Park JH, Shtraizent N, He X, Schuchman EH. 2007. Acid ceramidase is a novel factor required for early embryo survival. FASEB J. 21:1403-1409.
    • (2007) FASEB J , vol.21 , pp. 1403-1409
    • Eliyahu, E.1    Park, J.H.2    Shtraizent, N.3    He, X.4    Schuchman, E.H.5
  • 17
    • 0035929560 scopus 로고    scopus 로고
    • Human acid ceramidase: processing, glycosylation, and lysosomal targeting
    • Ferlinz K, et al. 2001. Human acid ceramidase: processing, glycosylation, and lysosomal targeting. J. Biol. Chem. 276:35352-35360.
    • (2001) J. Biol. Chem. , vol.276 , pp. 35352-35360
    • Ferlinz, K.1
  • 18
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121-141.
    • (2000) Genes Dev , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 19
  • 20
    • 69949113620 scopus 로고    scopus 로고
    • Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
    • Hait NC, et al. 2009. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 325:1254 -1257.
    • (2009) Science , vol.325 , pp. 1254-1257
    • Hait, N.C.1
  • 21
    • 0033120086 scopus 로고    scopus 로고
    • Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress
    • Hammer GD, et al. 1999. Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress. Mol. Cell 3:521-526.
    • (1999) Mol. Cell , vol.3 , pp. 521-526
    • Hammer, G.D.1
  • 22
    • 0030986236 scopus 로고    scopus 로고
    • A signature motif in transcriptional co-activators mediates binding to nuclear receptors
    • Heery DM, Kalkhoven E, Hoare S, Parker MG. 1997. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733-736.
    • (1997) Nature , vol.387 , pp. 733-736
    • Heery, D.M.1    Kalkhoven, E.2    Hoare, S.3    Parker, M.G.4
  • 23
    • 34249847751 scopus 로고    scopus 로고
    • Structural insights into corepressor recognition by antagonist-bound estrogen receptors
    • Heldring N, et al. 2007. Structural insights into corepressor recognition by antagonist-bound estrogen receptors. J. Biol. Chem. 282:10449 -10455.
    • (2007) J. Biol. Chem. , vol.282 , pp. 10449-10455
    • Heldring, N.1
  • 25
    • 0033523917 scopus 로고    scopus 로고
    • The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
    • Hu X, Lazar MA. 1999. The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature 402:93-96.
    • (1999) Nature , vol.402 , pp. 93-96
    • Hu, X.1    Lazar, M.A.2
  • 27
    • 14644398609 scopus 로고    scopus 로고
    • A boundary for histone acetylation allows distinct expression patterns of the Ad4BP/SF-1 and GCNF loci in adrenal cortex cells
    • Ishihara SL, Morohashi K. 2005. A boundary for histone acetylation allows distinct expression patterns of the Ad4BP/SF-1 and GCNF loci in adrenal cortex cells. Biochem. Biophys. Res. Commun. 329:554 -562.
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 554-562
    • Ishihara, S.L.1    Morohashi, K.2
  • 28
    • 0031020234 scopus 로고    scopus 로고
    • DAX- 1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita
    • Ito M, Yu R, Jameson JL. 1997. DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita. Mol. Cell. Biol. 17:1476 -1483.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1476-1483
    • Ito, M.1    Yu, R.2    Jameson, J.L.3
  • 29
    • 0032230230 scopus 로고    scopus 로고
    • Steroidogenic factor-1 contains a carboxy-terminal transcriptional activation domain that interacts with steroid receptor coactivator-1
    • Ito M, Yu RN, Jameson JL. 1998. Steroidogenic factor-1 contains a carboxy-terminal transcriptional activation domain that interacts with steroid receptor coactivator-1. Mol. Endocrinol. 12:290 -301.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 290-301
    • Ito, M.1    Yu, R.N.2    Jameson, J.L.3
  • 30
    • 0035813148 scopus 로고    scopus 로고
    • Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5
    • Jacob AL, Lund J, Martinez P, Hedin L. 2001. Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. J. Biol. Chem. 276:37659 -37664.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37659-37664
    • Jacob, A.L.1    Lund, J.2    Martinez, P.3    Hedin, L.4
  • 31
    • 5044236130 scopus 로고    scopus 로고
    • Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/ steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9
    • Komatsu T, et al. 2004. Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/ steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9. Mol. Endocrinol. 18:2451-2462.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2451-2462
    • Komatsu, T.1
  • 32
    • 13544263313 scopus 로고    scopus 로고
    • Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
    • Krylova IN, et al. 2005. Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell 120:343- 355.
    • (2005) Cell , vol.120 , pp. 343-355
    • Krylova, I.N.1
  • 34
    • 0026665062 scopus 로고
    • Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I
    • Lala DS, Rice DA, Parker KL. 1992. Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I. Mol. Endocrinol. 6:1249 -1258.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1249-1258
    • Lala, D.S.1    Rice, D.A.2    Parker, K.L.3
  • 35
    • 47649131293 scopus 로고    scopus 로고
    • Nuclear sphingolipids: metabolism and signaling
    • Ledeen RW, Wu G. 2008. Nuclear sphingolipids: metabolism and signaling. J. Lipid Res. 49:1176 -1186.
    • (2008) J. Lipid Res. , vol.49 , pp. 1176-1186
    • Ledeen, R.W.1    Wu, G.2
  • 36
    • 34748826098 scopus 로고    scopus 로고
    • Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase Θ facilitates induction of CYP17
    • Li D, et al. 2007. Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase Θ facilitates induction of CYP17. Mol. Cell. Biol. 27:6669-6685.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 6669-6685
    • Li, D.1
  • 37
    • 0033305584 scopus 로고    scopus 로고
    • Function of steroidogenic factor 1 domains in nuclear localization, transactivation, and interaction with transcription factor TFIIB and c-Jun
    • Li LA, et al. 1999. Function of steroidogenic factor 1 domains in nuclear localization, transactivation, and interaction with transcription factor TFIIB and c-Jun. Mol. Endocrinol. 13:1588 -1598.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 1588-1598
    • Li, L.A.1
  • 38
    • 13944276441 scopus 로고    scopus 로고
    • Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1
    • Li Y, et al. 2005. Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1. Mol. Cell 17:491-502.
    • (2005) Mol. Cell , vol.17 , pp. 491-502
    • Li, Y.1
  • 39
    • 0035937146 scopus 로고    scopus 로고
    • Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins
    • Linke T, et al. 2001. Interfacial regulation of acid ceramidase activity. Stimulation of ceramide degradation by lysosomal lipids and sphingolipid activator proteins. J. Biol. Chem. 276:5760 -5768.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5760-5768
    • Linke, T.1
  • 40
    • 67650234014 scopus 로고    scopus 로고
    • The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells
    • Lucki N, Sewer MB. 2009. The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells. Biochim. Biophys. Acta 1791:706- 713.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 706-713
    • Lucki, N.1    Sewer, M.B.2
  • 41
    • 84856294650 scopus 로고    scopus 로고
    • Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression
    • Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. 2012. Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Mol. Endocrinol. 26:228 -243.
    • (2012) Mol. Endocrinol. , vol.26 , pp. 228-243
    • Lucki, N.C.1    Bandyopadhyay, S.2    Wang, E.3    Merrill, A.H.4    Sewer, M.B.5
  • 42
    • 58149279854 scopus 로고    scopus 로고
    • Multiple roles for sphingolipids in steroid hormone biosynthesis
    • Lucki NC, Sewer MB. 2008. Multiple roles for sphingolipids in steroid hormone biosynthesis. Subcell. Biochem. 49:387- 412.
    • (2008) Subcell. Biochem. , vol.49 , pp. 387-412
    • Lucki, N.C.1    Sewer, M.B.2
  • 43
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: the second decade
    • Mangelsdorf DJ, et al. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835- 839.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1
  • 44
    • 0032213938 scopus 로고    scopus 로고
    • Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation
    • McInerney EM, et al. 1998. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12: 3357-3368.
    • (1998) Genes Dev , vol.12 , pp. 3357-3368
    • McInerney, E.M.1
  • 45
    • 0032548852 scopus 로고    scopus 로고
    • Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300
    • Monté D, DeWitte F, Hum DW. 1998. Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300. J. Biol. Chem. 273:4585- 4591.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4585-4591
    • Monté, D.1    DeWitte, F.2    Hum, D.W.3
  • 46
    • 0028783935 scopus 로고
    • Phospholipid composition, phospholipase A2 and sphingomyelinase activities in rat liver nuclear membrane and matrix
    • Neitcheva T, Peeva D. 1995. Phospholipid composition, phospholipase A2 and sphingomyelinase activities in rat liver nuclear membrane and matrix. Int. J. Biochem. Cell Biol. 27:995-1001.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 995-1001
    • Neitcheva, T.1    Peeva, D.2
  • 47
    • 11244309781 scopus 로고    scopus 로고
    • ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism
    • Ozbay T, Merrill AH, Jr, Sewer MB. 2004. ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism. Endocr. Res. 30:787-794.
    • (2004) Endocr. Res. , vol.30 , pp. 787-794
    • Ozbay, T.1    Merrill Jr., A.H.2    Sewer, M.B.3
  • 48
    • 32644440485 scopus 로고    scopus 로고
    • Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1
    • Ozbay T, Rowan A, Leon A, Patel P, Sewer MB. 2006. Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1. Endocrinology 147:1427-1437.
    • (2006) Endocrinology , vol.147 , pp. 1427-1437
    • Ozbay, T.1    Rowan, A.2    Leon, A.3    Patel, P.4    Sewer, M.B.5
  • 49
    • 33845296931 scopus 로고    scopus 로고
    • Acid ceramidase and human disease
    • Park J, Schuchuman E. 2006. Acid ceramidase and human disease. Biochim. Biophys. Acta 1758:2133-2138.
    • (2006) Biochim. Biophys. Acta , vol.1758 , pp. 2133-2138
    • Park, J.1    Schuchuman, E.2
  • 50
    • 18544386359 scopus 로고    scopus 로고
    • Steroidogenic factor 1: an essential mediator of endocrine development
    • Parker KL, et al. 2002. Steroidogenic factor 1: an essential mediator of endocrine development. Recent Prog. Horm. Res. 57:19 -36.
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 19-36
    • Parker, K.L.1
  • 51
    • 10644266103 scopus 로고    scopus 로고
    • Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
    • Payne AH, Hales DB. 2004. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr. Rev. 25: 947-970.
    • (2004) Endocr. Rev. , vol.25 , pp. 947-970
    • Payne, A.H.1    Hales, D.B.2
  • 52
    • 0033572656 scopus 로고    scopus 로고
    • Molecular determinants of nuclear receptorcorepressor interaction
    • Perissi V, et al. 1999. Molecular determinants of nuclear receptorcorepressor interaction. Genes Dev. 13:3198 -3208.
    • (1999) Genes Dev , vol.13 , pp. 3198-3208
    • Perissi, V.1
  • 53
    • 0037203342 scopus 로고    scopus 로고
    • Ceramide in apoptosis: an overview and current perspectives
    • Pettus BJ, Chalfant CE, Hannun YA. 2002. Ceramide in apoptosis: an overview and current perspectives. Biochim. Biophys. Acta 1585:114 -125.
    • (2002) Biochim. Biophys. Acta , vol.1585 , pp. 114-125
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 54
    • 80052332583 scopus 로고    scopus 로고
    • Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation
    • Plotnikov A, Chuderland D, Karamansha Y, Livnah O, Seger R. 2011. Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. Mol. Cell. Biol. 31:3515-3530.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 3515-3530
    • Plotnikov, A.1    Chuderland, D.2    Karamansha, Y.3    Livnah, O.4    Seger, R.5
  • 55
    • 0028287061 scopus 로고
    • The NCI-H295 cell line: a pluripotent model for human adrenocortical studies
    • Rainey WE, Bird IM, Mason JI. 1994. The NCI-H295 cell line: a pluripotent model for human adrenocortical studies. Mol. Cell. Endocrinol. 100:45-50.
    • (1994) Mol. Cell. Endocrinol. , vol.100 , pp. 45-50
    • Rainey, W.E.1    Bird, I.M.2    Mason, J.I.3
  • 56
    • 0034618754 scopus 로고    scopus 로고
    • Neutral/alkaline and acid ceramidase activities are actively released by murine endothelial cells
    • Romiti E, et al. 2000. Neutral/alkaline and acid ceramidase activities are actively released by murine endothelial cells. Biochem. Biophys. Res. Commun. 275:746 -751.
    • (2000) Biochem. Biophys. Res. Commun. , vol.275 , pp. 746-751
    • Romiti, E.1
  • 57
    • 33744792310 scopus 로고    scopus 로고
    • Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
    • Rosenfeld MG, Lunyak VV, Glass CK. 2006. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 20:1405-1428.
    • (2006) Genes Dev , vol.20 , pp. 1405-1428
    • Rosenfeld, M.G.1    Lunyak, V.V.2    Glass, C.K.3
  • 58
    • 58149242786 scopus 로고    scopus 로고
    • Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands
    • Sablin EP, et al. 2009. Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands. Mol. Endocrinol. 23:25-34.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 25-34
    • Sablin, E.P.1
  • 59
    • 0024412757 scopus 로고
    • Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol
    • Sakane F, Yamada K, Kanoh H. 1989. Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol. FEBS Lett. 255:409-413.
    • (1989) FEBS Lett , vol.255 , pp. 409-413
    • Sakane, F.1    Yamada, K.2    Kanoh, H.3
  • 60
    • 0035114217 scopus 로고    scopus 로고
    • Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer
    • Selzner M, et al. 2001. Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. Cancer Res. 61:1233-1240.
    • (2001) Cancer Res , vol.61 , pp. 1233-1240
    • Selzner, M.1
  • 61
    • 0036212259 scopus 로고    scopus 로고
    • Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription
    • Sewer MB, et al. 2002. Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription. Endocrinology 143: 1280-1290.
    • (2002) Endocrinology , vol.143 , pp. 1280-1290
    • Sewer, M.B.1
  • 62
    • 0038823652 scopus 로고    scopus 로고
    • ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex
    • Sewer MB, Waterman MR. 2003. ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex. Microsc. Res. Tech. 61:300 -307.
    • (2003) Microsc. Res. Tech. , vol.61 , pp. 300-307
    • Sewer, M.B.1    Waterman, M.R.2
  • 63
    • 0036228795 scopus 로고    scopus 로고
    • Adrenocorticotropin/cyclic adenosine 3', 5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity
    • Sewer MB, Waterman MR. 2002. Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity. Endocrinology 143:1769 -1777.
    • (2002) Endocrinology , vol.143 , pp. 1769-1777
    • Sewer, M.B.1    Waterman, M.R.2
  • 64
    • 0036668577 scopus 로고    scopus 로고
    • cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A
    • Sewer MB, Waterman MR. 2002. cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase A. J. Mol. Endocrinol. 29:163- 174.
    • (2002) J. Mol. Endocrinol. , vol.29 , pp. 163-174
    • Sewer, M.B.1    Waterman, M.R.2
  • 65
    • 0032569902 scopus 로고    scopus 로고
    • Interdomain communication regulating ligand binding by PPAR-gamma
    • Shao D, et al. 1998. Interdomain communication regulating ligand binding by PPAR-gamma. Nature 396:377-380.
    • (1998) Nature , vol.396 , pp. 377-380
    • Shao, D.1
  • 66
    • 45549093120 scopus 로고    scopus 로고
    • Autoproteolytic cleavage and activation of human acid ceramidase
    • Shtraizent N, et al. 2008. Autoproteolytic cleavage and activation of human acid ceramidase. J. Biol. Chem. 283:11253-11259.
    • (2008) J. Biol. Chem. , vol.283 , pp. 11253-11259
    • Shtraizent, N.1
  • 67
    • 0037135572 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate, a key cell signaling molecule
    • Spiegel S, Milstien S. 2002. Sphingosine 1-phosphate, a key cell signaling molecule. J. Biol. Chem. 277:25851-25854.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25851-25854
    • Spiegel, S.1    Milstien, S.2
  • 68
    • 0027450247 scopus 로고
    • Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal
    • Staels B, Hum DW, Miller WL. 1993. Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal. Mol. Endocrinol. 7:423- 433.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 423-433
    • Staels, B.1    Hum, D.W.2    Miller, W.L.3
  • 69
    • 0033784938 scopus 로고    scopus 로고
    • Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry
    • Sullards MC. 2000. Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry. Methods Enzymol. 312:32- 45.
    • (2000) Methods Enzymol , vol.312 , pp. 32-45
    • Sullards, M.C.1
  • 70
    • 0035970197 scopus 로고    scopus 로고
    • Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
    • Sullards MC, Merrill AH, Jr. 2001. Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Sci. STKE 2001:pl1.
    • (2001) Sci. STKE , vol.2001
    • Sullards, M.C.1    Merrill Jr., A.H.2
  • 71
    • 0037214280 scopus 로고    scopus 로고
    • LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1
    • Suzuki T, Kasahara M, Yoshioka H, Morohashi K, Umesono K. 2003. LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1. Mol. Cell. Biol. 23:238 -249.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 238-249
    • Suzuki, T.1    Kasahara, M.2    Yoshioka, H.3    Morohashi, K.4    Umesono, K.5
  • 72
    • 0024745630 scopus 로고
    • Existence of Mg2 -dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells
    • Tamiya-Koizumi K, Umekawa H, Yoshida S, Kojima K. 1989. Existence of Mg2 -dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells. J. Biochem. 106:593-598.
    • (1989) J. Biochem. , vol.106 , pp. 593-598
    • Tamiya-Koizumi, K.1    Umekawa, H.2    Yoshida, S.3    Kojima, K.4
  • 73
    • 0033120030 scopus 로고    scopus 로고
    • Ligandindependent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1
    • Tremblay A, Tremblay GB, Labrie F, Giguere V. 1999. Ligandindependent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1. Mol. Cell 3:513-519.
    • (1999) Mol. Cell , vol.3 , pp. 513-519
    • Tremblay, A.1    Tremblay, G.B.2    Labrie, F.3    Giguere, V.4
  • 74
    • 33847011721 scopus 로고    scopus 로고
    • Steroidogenic factor-1 is a sphingolipid binding protein
    • Urs AN, et al. 2007. Steroidogenic factor-1 is a sphingolipid binding protein. Mol. Cell. Endocrinol. 265-266:174 -178.
    • (2007) Mol. Cell. Endocrinol. , vol.265-266 , pp. 174-178
    • Urs, A.N.1
  • 75
    • 33751250805 scopus 로고    scopus 로고
    • Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1
    • Urs AN, Dammer E, Sewer M. 2006. Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1. Endocrinology 147: 5249-5258.
    • (2006) Endocrinology , vol.147 , pp. 5249-5258
    • Urs, A.N.1    Dammer, E.2    Sewer, M.3
  • 76
    • 0026317132 scopus 로고
    • Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme
    • Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH, Jr. 1991. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J. Biol. Chem. 266: 14486-14490.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14486-14490
    • Wang, E.1    Norred, W.P.2    Bacon, C.W.3    Riley, R.T.4    Merrill Jr., A.H.5
  • 77
    • 21144448184 scopus 로고    scopus 로고
    • The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
    • Wang W, et al. 2005. The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1. Proc. Natl. Acad. Sci. U. S. A. 102:7505-7510.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 7505-7510
    • Wang, W.1
  • 78
    • 33744807983 scopus 로고    scopus 로고
    • The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function
    • Wattenberg BW, Pitson SM, Raben DM. 2006. The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function. J. Lipid Res. 47:1128 -1139.
    • (2006) J. Lipid Res. , vol.47 , pp. 1128-1139
    • Wattenberg, B.W.1    Pitson, S.M.2    Raben, D.M.3
  • 79
    • 29444454897 scopus 로고    scopus 로고
    • Adrenocorticotropic hormonemediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation
    • Winnay JN, Hammer GD. 2006. Adrenocorticotropic hormonemediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation. Mol. Endocrinol. 20:147- 166.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 147-166
    • Winnay, J.N.1    Hammer, G.D.2
  • 80
    • 77249093981 scopus 로고    scopus 로고
    • PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1
    • Yazawa T, et al. 2010. PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1. Mol. Endocrinol. 24:485- 496.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 485-496
    • Yazawa, T.1
  • 81
    • 0034704063 scopus 로고    scopus 로고
    • DAX- 1 functions as an LXXLL-containing corepressor for activated estrogen receptors
    • Zhang H, Thomsen JS, Johansson L, Gustafsson JA, Treuter E. 2000. DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors. J. Biol. Chem. 275:39855-39859.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39855-39859
    • Zhang, H.1    Thomsen, J.S.2    Johansson, L.3    Gustafsson, J.A.4    Treuter, E.5
  • 82
    • 0034464659 scopus 로고    scopus 로고
    • PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors, including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1)
    • Zhou D, et al. 2000. PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors, including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1). Mol. Endocrinol. 14:986- 998.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 986-998
    • Zhou, D.1


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