-
1
-
-
77950413847
-
Extracellular-regulated kinase-mitogen-activated protein kinase cascade: unsolved issues
-
Bodart, J. F. 2010. Extracellular-regulated kinase-mitogen-activated protein kinase cascade: unsolved issues. J. Cell. Biochem. 109:850-857.
-
(2010)
J. Cell. Biochem.
, vol.109
, pp. 850-857
-
-
Bodart, J.F.1
-
2
-
-
0033081066
-
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
-
Brunet, A., et al. 1999. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J. 18:664-674.
-
(1999)
EMBO J
, vol.18
, pp. 664-674
-
-
Brunet, A.1
-
3
-
-
33846590071
-
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
-
Burgermeister, E., et al. 2007. Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol. Cell. Biol. 27:803-817.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 803-817
-
-
Burgermeister, E.1
-
4
-
-
77951724799
-
The Ras-ERK pathway: understanding site-specific signaling provides hope of new anti-tumor therapies
-
Calvo, F., L. Agudo-Ibanez, and P. Crespo. 2010. The Ras-ERK pathway: understanding site-specific signaling provides hope of new anti-tumor therapies. Bioessays 32:412-421.
-
(2010)
Bioessays
, vol.32
, pp. 412-421
-
-
Calvo, F.1
Agudo-Ibanez, L.2
Crespo, P.3
-
5
-
-
50549083633
-
Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes
-
Casar, B., A. Pinto, and P. Crespo. 2008. Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes. Mol. Cell 31:708-721.
-
(2008)
Mol. Cell
, vol.31
, pp. 708-721
-
-
Casar, B.1
Pinto, A.2
Crespo, P.3
-
6
-
-
52049108218
-
Identification and characterization of a general nuclear translocation signal in signaling proteins
-
Chuderland, D., A. Konson, and R. Seger. 2008. Identification and characterization of a general nuclear translocation signal in signaling proteins. Mol. Cell 31:850-861.
-
(2008)
Mol. Cell
, vol.31
, pp. 850-861
-
-
Chuderland, D.1
Konson, A.2
Seger, R.3
-
7
-
-
21644449056
-
Protein-protein interactions in the regulation of the extracellular signal-regulated kinase
-
Chuderland, D., and R. Seger. 2005. Protein-protein interactions in the regulation of the extracellular signal-regulated kinase. Mol. Biotechnol. 29: 57-74.
-
(2005)
Mol. Biotechnol.
, vol.29
, pp. 57-74
-
-
Chuderland, D.1
Seger, R.2
-
8
-
-
38349116517
-
Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
-
Duncan, J. S., and D. W. Litchfield. 2008. Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim. Biophys. Acta 1784:33-47.
-
(2008)
Biochim. Biophys. Acta
, vol.1784
, pp. 33-47
-
-
Duncan, J.S.1
Litchfield, D.W.2
-
10
-
-
18044405015
-
PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase
-
Formstecher, E., et al. 2001. PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. Dev. Cell 1:239-250.
-
(2001)
Dev. Cell
, vol.1
, pp. 239-250
-
-
Formstecher, E.1
-
11
-
-
0030972494
-
Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase
-
Fukuda, M., Y. Gotoh, and E. Nishida. 1997. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 16:1901-1908.
-
(1997)
EMBO J
, vol.16
, pp. 1901-1908
-
-
Fukuda, M.1
Gotoh, Y.2
Nishida, E.3
-
12
-
-
70449591270
-
A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells
-
Galli, S., et al. 2009. A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells. PLoS One 4:e7541.
-
(2009)
PLoS One
, vol.4
-
-
Galli, S.1
-
13
-
-
0040182590
-
Nuclear protein import
-
Gorlich, D. 1997. Nuclear protein import. Curr. Opin. Cell Biol. 9:412-419.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 412-419
-
-
Gorlich, D.1
-
14
-
-
77957803826
-
CK2 inhibition induces apoptosis via the ER stress response
-
Hessenauer, A., C. C. Schneider, C. Gotz, and M. Montenarh. 2011. CK2 inhibition induces apoptosis via the ER stress response. Cell. Signal. 23:145-151.
-
(2011)
Cell. Signal.
, vol.23
, pp. 145-151
-
-
Hessenauer, A.1
Schneider, C.C.2
Gotz, C.3
Montenarh, M.4
-
15
-
-
76749088358
-
Pathological roles of MAPK signaling pathways in human diseases
-
Kim, E. K., and E. J. Choi. 2010. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta 1802:396-405.
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 396-405
-
-
Kim, E.K.1
Choi, E.J.2
-
16
-
-
27644575157
-
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
-
Kolch, W. 2005. Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat. Rev. Mol. Cell Biol. 6:827-837.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 827-837
-
-
Kolch, W.1
-
17
-
-
77955942384
-
Functional proteomics to dissect tyrosine kinase signalling pathways in cancer
-
Kolch, W., and A. Pitt. 2010. Functional proteomics to dissect tyrosine kinase signalling pathways in cancer. Nat. Rev. Cancer 10:618-629.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 618-629
-
-
Kolch, W.1
Pitt, A.2
-
18
-
-
0023645087
-
Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides
-
Kuenzel, E. A., J. A. Mulligan, J. Sommercorn, and E. G. Krebs. 1987. Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides. J. Biol. Chem. 262:9136-9140.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9136-9140
-
-
Kuenzel, E.A.1
Mulligan, J.A.2
Sommercorn, J.3
Krebs, E.G.4
-
20
-
-
0037269847
-
Protein kinase CK2: structure, regulation and role in cellular decisions of life and death
-
Litchfield, D. W. 2003. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem. J. 369:1-15.
-
(2003)
Biochem. J.
, vol.369
, pp. 1-15
-
-
Litchfield, D.W.1
-
21
-
-
0035036212
-
Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin
-
Lorenzen, J. A., et al. 2001. Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin. Development 128:1403-1414.
-
(2001)
Development
, vol.128
, pp. 1403-1414
-
-
Lorenzen, J.A.1
-
22
-
-
0037334895
-
One-thousand-and-one substrates of protein kinase CK2?
-
Meggio, F., and L. A. Pinna. 2003. One-thousand-and-one substrates of protein kinase CK2? FASEB J. 17:349-368.
-
(2003)
FASEB J
, vol.17
, pp. 349-368
-
-
Meggio, F.1
Pinna, L.A.2
-
24
-
-
34250166523
-
Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases
-
Niefind, K., C. W. Yde, I. Ermakova, and O. G. Issinger. 2007. Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases. J. Mol. Biol. 370:427-438.
-
(2007)
J. Mol. Biol.
, vol.370
, pp. 427-438
-
-
Niefind, K.1
Yde, C.W.2
Ermakova, I.3
Issinger, O.G.4
-
25
-
-
0030964105
-
Nucleocytoplasmic transport: signals, mechanisms and regulation
-
Nigg, E. A. 1997. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386:779-787.
-
(1997)
Nature
, vol.386
, pp. 779-787
-
-
Nigg, E.A.1
-
26
-
-
0032516522
-
Protein kinase CK2alpha′ is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation
-
Orlandini, M., et al. 1998. Protein kinase CK2alpha′ is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation. J. Biol. Chem. 273:21291-21297.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21291-21297
-
-
Orlandini, M.1
-
27
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z., and W. Minor. 1997. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:307-326.
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
28
-
-
84872864632
-
Protein kinase CK2 in health and disease: CK2: an ugly duckling in the kinome pond
-
Pinna, L. A., and J. E. Allende. 2009. Protein kinase CK2 in health and disease: CK2: an ugly duckling in the kinome pond. Cell. Mol. Life Sci. 66:1795-1799.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1795-1799
-
-
Pinna, L.A.1
Allende, J.E.2
-
29
-
-
79955518288
-
The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation
-
in press
-
Plotnikov, A., E. Zehorai, S. Procaccia, and R. Seger. The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochim. Biophys. Acta, in press.
-
Biochim. Biophys. Acta
-
-
Plotnikov, A.1
Zehorai, E.2
Procaccia, S.3
Seger, R.4
-
30
-
-
0037779018
-
A graphical user interface to the CCP4 program suite
-
Potterton, E., P. Briggs, M. Turkenburg, and E. Dodson. 2003. A graphical user interface to the CCP4 program suite. Acta Crystallogr. D 59:1131-1137.
-
(2003)
Acta Crystallogr. D
, vol.59
, pp. 1131-1137
-
-
Potterton, E.1
Briggs, P.2
Turkenburg, M.3
Dodson, E.4
-
31
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman, M., W. Chen, and M. H. Cobb. 2007. Differential regulation and properties of MAPKs. Oncogene 26:3100-3112.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
32
-
-
0030855766
-
Mitogenactivated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions
-
Reszka, A. A., J. C. Bulinski, E. G. Krebs, and E. H. Fischer. 1997. Mitogenactivated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions. Mol. Biol. Cell 8:1219-1232.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 1219-1232
-
-
Reszka, A.A.1
Bulinski, J.C.2
Krebs, E.G.3
Fischer, E.H.4
-
33
-
-
0037112514
-
Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells
-
Romieu-Mourez, R., E. Landesman-Bollag, D. C. Seldin, and G. E. Sonenshein. 2002. Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells. Cancer Res. 62:6770-6778.
-
(2002)
Cancer Res
, vol.62
, pp. 6770-6778
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Sonenshein, G.E.4
-
34
-
-
0032749494
-
Identification of a cytoplasmic-retention sequence in ERK2
-
Rubinfeld, H., T. Hanoch, and R. Seger. 1999. Identification of a cytoplasmic-retention sequence in ERK2. J. Biol. Chem. 274:30349-30352.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30349-30352
-
-
Rubinfeld, H.1
Hanoch, T.2
Seger, R.3
-
35
-
-
75349084777
-
Addiction to protein kinase CK2: a common denominator of diverse cancer cells?
-
Ruzzene, M., and L. A. Pinna. 2010. Addiction to protein kinase CK2: a common denominator of diverse cancer cells? Biochim. Biophys. Acta 1804: 499-504.
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 499-504
-
-
Ruzzene, M.1
Pinna, L.A.2
-
36
-
-
27944499451
-
An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets
-
Schwartz, D., and S. P. Gygi. 2005. An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets. Nat. Biotechnol. 23:1391-1398.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1391-1398
-
-
Schwartz, D.1
Gygi, S.P.2
-
37
-
-
68149132138
-
Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade
-
Shaul, Y. D., G. Gibor, A. Plotnikov, and R. Seger. 2009. Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. Genes Dev. 23:1779-1790.
-
(2009)
Genes Dev
, vol.23
, pp. 1779-1790
-
-
Shaul, Y.D.1
Gibor, G.2
Plotnikov, A.3
Seger, R.4
-
38
-
-
33644878839
-
ERK1c regulates Golgi fragmentation during mitosis
-
Shaul, Y. D., and R. Seger. 2006. ERK1c regulates Golgi fragmentation during mitosis. J. Cell Biol. 172:885-897.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 885-897
-
-
Shaul, Y.D.1
Seger, R.2
-
39
-
-
34547204160
-
The MEK/ERK cascade: from signaling specificity to diverse functions
-
Shaul, Y. D., and R. Seger. 2007. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta 1773:1213-1226.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1213-1226
-
-
Shaul, Y.D.1
Seger, R.2
-
40
-
-
77957291965
-
Nuclear entry of activated MAPK is restricted in primary ovarian and mammary epithelial cells
-
Smith, E. R., et al. 2010. Nuclear entry of activated MAPK is restricted in primary ovarian and mammary epithelial cells. PLoS One 5:e9295.
-
(2010)
PLoS One
, vol.5
-
-
Smith, E.R.1
-
41
-
-
70349186117
-
Protein kinase CK2 in health and disease: from birth to death: the role of protein kinase CK2 in the regulation of cell proliferation and survival
-
St-Denis, N. A., and D. W. Litchfield. 2009. Protein kinase CK2 in health and disease: from birth to death: the role of protein kinase CK2 in the regulation of cell proliferation and survival. Cell. Mol. Life Sci. 66:1817-1829.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1817-1829
-
-
St-Denis, N.A.1
Litchfield, D.W.2
-
42
-
-
0026117693
-
The streak seeding technique in protein crystallization
-
Stura, E. A., and I. A. Wilson. 1991. The streak seeding technique in protein crystallization. J. Cryst. Growth 110:270-282.
-
(1991)
J. Cryst. Growth
, vol.110
, pp. 270-282
-
-
Stura, E.A.1
Wilson, I.A.2
-
43
-
-
78049390388
-
Phosphorylation of the RNase III enzyme Drosha at serine300 or serine302 is required for its nuclear localization
-
Tang, X., Y. Zhang, L. Tucker, and B. Ramratnam. 2010. Phosphorylation of the RNase III enzyme Drosha at serine300 or serine302 is required for its nuclear localization. Nucleic Acids Res. 38:6610-6619.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6610-6619
-
-
Tang, X.1
Zhang, Y.2
Tucker, L.3
Ramratnam, B.4
-
44
-
-
33947513279
-
Modulation of replicative senescence of diploid human cells by nuclear ERK signaling
-
Tresini, M., A. Lorenzini, C. Torres, and V. J. Cristofalo. 2007. Modulation of replicative senescence of diploid human cells by nuclear ERK signaling. J. Biol. Chem. 282:4136-4151.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4136-4151
-
-
Tresini, M.1
Lorenzini, A.2
Torres, C.3
Cristofalo, V.J.4
-
45
-
-
0035788131
-
Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps
-
Vagin, A. A., and M. N. Isupov. 2001. Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps. Acta Crystallogr. D Biol. Crystallogr. 57:1451- 1456.
-
(2001)
Acta Crystallogr. D Biol. Crystallogr.
, vol.57
-
-
Vagin, A.A.1
Isupov, M.N.2
-
46
-
-
34948906397
-
Nuclear import of c-Jun is mediated by multiple transport receptors
-
Waldmann, I., S. Walde, and R. H. Kehlenbach. 2007. Nuclear import of c-Jun is mediated by multiple transport receptors. J. Biol. Chem. 282:27685- 27692.
-
(2007)
J. Biol. Chem.
, vol.282
-
-
Waldmann, I.1
Walde, S.2
Kehlenbach, R.H.3
-
47
-
-
0035816678
-
Involvement of the activation loop of ERK in the detachment from cytosolic anchoring
-
Wolf, I., et al. 2001. Involvement of the activation loop of ERK in the detachment from cytosolic anchoring. J. Biol. Chem. 276:24490-24497.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24490-24497
-
-
Wolf, I.1
-
48
-
-
0033039809
-
Murine protein kinase CK2: gene and oncogene
-
Xu, X., E. Landesman-Bollag, P. L. Channavajhala, and D. C. Seldin. 1999. Murine protein kinase CK2: gene and oncogene. Mol. Cell. Biochem. 191:65-74.
-
(1999)
Mol. Cell. Biochem.
, vol.191
, pp. 65-74
-
-
Xu, X.1
Landesman-Bollag, E.2
Channavajhala, P.L.3
Seldin, D.C.4
-
49
-
-
53049104873
-
Preferential utilization of Imp7/8 in nuclear import of Smads
-
Yao, X., X. Chen, C. Cottonham, and L. Xu. 2008. Preferential utilization of Imp7/8 in nuclear import of Smads. J. Biol. Chem. 283:22867-22874.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22867-22874
-
-
Yao, X.1
Chen, X.2
Cottonham, C.3
Xu, L.4
-
50
-
-
73249143291
-
The ERK signaling cascade-views from different subcellular compartments
-
Yao, Z., and R. Seger. 2009. The ERK signaling cascade-views from different subcellular compartments. Biofactors 35:407-416.
-
(2009)
Biofactors
, vol.35
, pp. 407-416
-
-
Yao, Z.1
Seger, R.2
-
51
-
-
35348957232
-
Mutations in ERK2 binding sites affect nuclear entry
-
Yazicioglu, M. N., et al. 2007. Mutations in ERK2 binding sites affect nuclear entry. J. Biol. Chem. 282:28759-28767.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 28759-28767
-
-
Yazicioglu, M.N.1
-
52
-
-
30944447568
-
The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions
-
Yoon, S., and R. Seger. 2006. The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24: 21-44.
-
(2006)
Growth Factors
, vol.24
, pp. 21-44
-
-
Yoon, S.1
Seger, R.2
-
53
-
-
71849119627
-
The subcellular localization of MEK and ERK-a novel nuclear translocation signal (NTS) paves a way to the nucleus
-
Zehorai, E., Z. Yao, A. Plotnikov, and R. Seger. 2010. The subcellular localization of MEK and ERK-a novel nuclear translocation signal (NTS) paves a way to the nucleus. Mol. Cell. Endocrinol. 314:213-220.
-
(2010)
Mol. Cell. Endocrinol.
, vol.314
, pp. 213-220
-
-
Zehorai, E.1
Yao, Z.2
Plotnikov, A.3
Seger, R.4
|