Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: Integration of hormone signaling in reproduction and stress

Molecular Cell

Volumn 3, Issue 4, 1999, Pages 521-526

  Hammer, Gary D ^a,b   Krylova, Irina ^a   Zhang, Yixian ^a   Darimont, Beatrice D ^a   Simpson, Kimberly ^c   Weigel, Nancy L ^a   Ingraham, Holly A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; SERINE DERIVATIVE; STEROIDOGENIC FACTOR 1;

ARTICLE; GENE EXPRESSION; HORMONE SYNTHESIS; NONHUMAN; PHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN MODIFICATION; REPRODUCTION; SIGNAL TRANSDUCTION; STRESS;

VERTEBRATA;

EID: 0033120086     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80480-3     Document Type: Article

References (31)

1. Carlone, D.L., and Richards, J.S. (1997). Functional interactions, phosphorylation, and levels of 3′,5′-cyclic adenosine monophosphate-regulatory element binding protein and steroidogenic factor-1 mediate hormone-regulated and constitutive expression of aromatase in gonadal cells. Mol. Endocrinol. 11, 292-304.
2. Christenson, L.K., McAllister, J.M., Martin, K.O., Javitt, N.B., Osborne, T.F., and Strauss, J.F., III (1998). Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions. J. Biol. Chem. 273, 30729-30735.
3. Crawford, P.A., Sadovsky, Y., Woodson, K., Lee, S.L., and Milbrandt, J. (1995). Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice. Mol. Cell. Biol. 15, 4331- 4336.
4. Crawford, P.A., Polish, J.A., Ganpule, G., and Sadovsky, Y. (1997). The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1. Mol. Endocrinol. 11, 1626-1635.
5. Darimont, B.D., Wagner, R.L., Apriletti, J.W., Stallcup, M.R., Kushner, P.J., Baxter, J.D., Fletterick, R.J., and Yamamoto, K.R. (1998). Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev. 12, 3343-3356.
6. Enyeart, J.J., Boyd, R.T., and Enyeart, J.A. (1996). ACTH and AII differentially stimulate steroid hormone orphan receptor mRNAs in adrenal cortical cells. Mol. Cell. Endocrinol. 724, 97-110.
7. Hong, S.-H., Wong, C.-W., and Privalsky, M.L. (1998). Signaling by tyrosine kinases negatively regulates the interaction between transcription factors and SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) corepressor. Mol. Endocrinol. 12, 1161-1171.
8. Hu, E., Kim, J.B., Sarraf, P., and Spiegelman, B.M. (1996). Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 274, 2100-2103.
9. Ikeda, Y., Shen, W.H., Ingraham, H.A., and Parker, K.L. (1994). Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol. Endocrinol. 8, 654-662.
10. Ingraham, H.A., Lala, D.S., Ikeda, Y., Luo, X., Shen, W.H., Nachtigal, M.W., Abbud, R., Nilson, J.H., and Parker, K.L. (1994). The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes Dev. 8, 2302-2312.
11. Ito, M., Yu, R.N., and Jameson, J.L. (1998). Steroidogenic factor-1 contains a carboxy-terminal transcriptional activation domain that interacts with steroid receptor coactivator-1. Mol. Endocrinol. 12, 290-301.
12. Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., et al. (1995). Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270, 1491-1494.
13. Lala, D.S., Syka, P.M., Lazarchik, S.B., Mangelsdorf, D.J., Parker, K.L., and Heyman, R.A. (1997). Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols. Proc. Natl. Acad. Sci. USA 94, 4895-4900.
14. Lavinsky, R.M., Jepsen, K., Heinzel, T., Torchia, J., Mullen, T.M., Schiff, R., Del-Rio, A.L., Ricote, M., Ngo, S., Gemsch, J., et al. (1998). Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc. Natl. Acad. Sci. USA 95, 2920-2925.
15. Luo, X., Ikeda, Y., and Parker, K.L. (1994). A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77, 481-490.
16. Mangelsdorf, D.J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., and Evan, R.M. (1995). The nuclear receptor superfamily: The second decade. Cell 83, 835-839.
17. Mellon, S.H., and Bair, S.R. (1998). 25-Hydroxycholesterol is not a ligand for the orphan nuclear receptor steroidogenic factor-1 (SF-1). Endocrinology 139, 3026-3029.
18. Nachtigal, M.W., Hirokawa, Y., Enyeart-Vanhouten, D.L., Flanagan, J.N., Hammer, G.D., and Ingraham, H.A. (1998). Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell 93, 445-454.
19. Nomura, M., Kawabe, K., Matsushita, S., Oka, S., Hatano, O., Harada, N., Nawata, H., and Morohashi, K.-I. (1998). Adrenocortical and gonadal expression of the mammalian ftz-f1 gene encoding AD4BP/SF-1 is independent of pituitary control. J. Biochem. 124, 111-118.
20. Parker, K.L., and Schimmer, B.P. (1997). Steroidogenic factor 1: a key determinant of endocrine development and function. EndocriNol. Rev. 13, 361-377.
21. Roberson, M.S., Misra-Press, A., Laurance, M.E., Stork, P.J., and Maurer, R.A. (1995). A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone. Mol. Cell. Biol. 15, 3531- 3539.
22. Sadovsky, Y., Crawford, P.A., Woodson, K.G., Polish, J.A., Clements, M.A., Tourtellotte, L.M., Simburger, K., and Milbrandt, J. (1995). Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc. Natl. Acad. Sci. USA 92, 10939-10943.
23. Shao, D., Rangwala, S.M., Bailey, ST., Krskow, S.L., Reginato, M.J., and Lazar, M.A. (1998). Interdomain communication regulating ligand binding by PPARγ. Nature 396, 377-380.
24. Shen, W.H., Moore, C.C., Ikeda, Y., Parker, K.L., and Ingraham, H.A. (1994). Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: A link to the sex determination cascade. Cell 77, 651-661.
25. Sugawara, T., Holt, J.A., Kiriakidou, M., and Strauss, J.F., III (1996). Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene. Biochemistry 35, 9052-9059.
26. Sundaresan, S., Colin, I.M., Pestell, R.G., and Jameson, J.L. (1996). Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: Evidence for the involvement of protein kinase C. Endocrinology 137, 304-311.
27. Tremblay, A., Tremblay, G.B., Labrie, F., and Giguère, V. (1999). Ligand-independent recruitment of SRC-1 to estrogen receptor β through phosphorylation of activation function AF-1. Mol. Cell 3, this issue, 513-519.
28. Vossler, M.R., Yao, H., York, R.D., Pan, M.G., Rim, C.S., and Stork, P.J. (1997). Camp activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89, 73-82.
29. Weigel, N.L. (1996). Steroid hormone receptors and their regulation by phosphorylation. Biochem. J. 319, 657-667.
30. Wilson, T.E., Fahrner, T.J., and Milbrandt, J. (1993). The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction. Mol. Cell. Biol. 13, 5794-5804.
31. Zhang, P., and Mellon, S.H. (1996). The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3′,5′-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase). Mol. Endocrinol. 10, 147-158.