Planar Cell Polarity in Coordinated and Directed Movements

Current Topics in Developmental Biology

Volumn 101, Issue , 2012, Pages 77-110

  Tada, Masazumi ^a   Kai, Masatake ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Collective cell migration; Convergent extension; Gastrulation; Planar cell polarity; Wnt

Indexed keywords

EID: 84868632765     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394592-1.00004-1     Document Type: Chapter

References (155)

1. Albertson R., Doe C. Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry. Nature Cell Biology 2003, 5:166-170.
2. Bastock R., Strutt H., Strutt D. Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning. Development 2003, 130:3007-3014.
3. Bertet C., Sulak L., Lecuit T. Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation. Nature 2004, 429:667-671.
4. Bingham S., Higashijima S., Okamoto H., Chandrasekhar A. The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Developmental Biology 2002, 242:149-160.
5. Blankenship J.T., Backovic S.T., Sanny J.S., Weitz O., Zallen J.A. Multicellular rosette formation links planar cell polarity to tissue morphogenesis. Developmental Cell 2006, 11:459-470.
6. Buechling T., Bartscherer K., Ohkawara B., Chaudhary V., Spirohn K., Niehrs C., et al. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Current Biology 2010, 20:1263-1268.
7. Carmon K.S., Gong X., Lin Q., Thomas A., Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:11452-11457.
8. Carmona-Fontaine C., Matthews H.K., Kuriyama S., Moreno M., Dunn G.A., Parsons M., et al. Contact inhibition of locomotion in vivo controls neural crest directional migration. Nature 2008, 456:957-961.
9. Carmona-Fontaine C., Theveneau E., Tzekou A., Tada M., Woods M., Page K.M., et al. Complement fragment C3a controls mutual cell attraction during collective cell migration. Developmental Cell 2011, 21:1026-1037.
10. Carreira-Barbosa F., Concha M.L., Takeuchi M., Ueno N., Wilson S.W., Tada M. Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development 2003, 130:4037-4046.
11. Carreira-Barbosa F., Kajita M., Morel V., Wada H., Okamoto H., Martinez Arias A., et al. Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development 2009, 136:383-392.
12. Chacon-Heszele M.F., Ren D., Reynolds A.B., Chi F., Chen P. Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin. Development 2012, 139:968-978.
13. Chen X., Gumbiner B.M. Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. The Journal of Cell Biology 2006, 174:301-313.
14. Chen W., ten Berge D., Brown J., Ahn S., Hu L.A., Miller W.E., et al. Dishevelled 2 recruits β-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 2003, 301:1391-1394.
15. Chung H.A., Hyodo-Miura J., Nagamune T., Ueno N. FGF signal regulates gastrulation cell movements and morphology through its target NRH. Developmental Biology 2005, 282:95-110.
16. Ciruna B., Jenny A., Lee D., Mlodzik M., Schier A.F. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 2006, 439:220-224.
17. Cui C., Yang X., Chuai M., Glazier J.A., Weijer C.J. Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Developmental Biology 2005, 284:37-47.
18. Curtin J.A., Quint E., Tsipouri V., Arkell R.M., Cattanach B., Copp A.J., et al. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Current Biology 2003, 13:1129-1133.
19. Darken R.S., Scola A.M., Rakeman A.S., Das G., Mlodzik M., Wilson P.A. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. The EMBO Journal 2002, 21:976-985.
20. Daulat A.M., Luu O., Sing A., Zhang L., Wrana J.L., McNeill H., et al. Mink1 regulates beta-catenin-independent Wnt signaling via Prickle phosphorylation. Molecular and Cellular Biology 2012, 32:173-185.
21. Davidson L.A., Marsden M., Keller R., Desimone D.W. Integrin α5β1 and fibronectin regulate polarized cell protrusions required for Xenopus convergence and extension. Current Biology 2006, 16:833-844.
22. de Lau W., Barker N., Low T.Y., Koo B.K., Li V.S., Teunissen H., et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 2011, 476:293-297.
23. Diz-Munoz A., Krieg M., Bergert M., Ibarlucea-Benitez I., Muller D.J., Paluch E., et al. Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biology 2010, 8:e1000544.
24. Djiane A., Riou J., Umbhauer M., Boucaut J., Shi D. Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 2000, 127:3091-3100.
25. Dzamba B.J., Jakab K.R., Marsden M., Schwartz M.A., DeSimone D.W. Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Developmental Cell 2009, 16:421-432.
26. Elul T., Keller R. Monopolar protrusive activity: A new morphogenic cell behavior in the neural plate dependent on vertical interactions with the mesoderm in Xenopus. Developmental Biology 2000, 224:3-19.
27. Elul T., Koehl M.A., Keller R. Cellular mechanism underlying neural convergent extension in Xenopus laevis embryos. Developmental Biology 1997, 191:243-258.
28. Formstone C.J., Mason I. Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Developmental Biology 2005, 282:320-335.
29. Friedl P., Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nature Reviews. Molecular Cell Biology 2009, 10:445-457.
30. Gao B., Song H., Bishop K., Elliot G., Garrett L., English M.A., et al. Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Developmental Cell 2011, 20:163-176.
31. Gerdes J.M., Liu Y., Zaghloul N.A., Leitch C.C., Lawson S.S., Kato M., et al. Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nature Genetics 2007, 39:1350-1360.
32. Glinka A., Dolde C., Kirsch N., Huang Y.L., Kazanskaya O., Ingelfinger D., et al. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling. EMBO Reports 2011, 12:1055-1061.
33. Gong Y., Mo C., Fraser S.E. Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature 2004, 430:689-693.
34. Goto T., Davidson L., Asashima M., Keller R. Planar cell polarity genes regulate polarized extracellular matrix deposition during frog gastrulation. Current Biology 2005, 15:787-793.
35. Goto T., Keller R. The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. Developmental Biology 2002, 247:165-181.
36. Gray R.S., Roszko I., Solnica-Krezel L. Planar cell polarity: Coordinating morphogenetic cell behaviors with embryonic polarity. Developmental Cell 2011, 21:120-133.
37. Habas R., Dawid I.B., He X. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes & Development 2003, 17:295-309.
38. Habas R., Kato Y., He X. Wnt/Frizzled activation of rho regulates vertebrate gastrulation and requires a novel formin homology protein daam1. Cell 2001, 107:843-854.
39. Hamblet N.S., Lijam N., Ruiz-Lozano P., Wang J., Yang Y., Luo Z., et al. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development 2002, 129:5827-5838.
40. Heisenberg C.P., Tada M., Rauch G.J., Saude L., Concha M.L., Geisler R., et al. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 2000, 405:76-81.
41. Hikasa H., Shibata M., Hiratani I., Taira M. The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling. Development 2002, 129:5227-5239.
42. Hyodo-Miura J., Yamamoto T.S., Hyodo A.C., Iemura S., Kusakabe M., Nishida E., et al. XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation. Developmental Cell 2006, 11:69-79.
43. Iioka H., Iemura S., Natsume T., Kinoshita N. Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility. Nature Cell Biology 2007, 9:813-821.
44. Jenny A., Reynolds-Kenneally J., Das G., Burnett M., Mlodzik M. Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nature Cell Biology 2005, 7:691-697.
45. Jessen J.R., Topczewski J., Bingham S., Sepich D.S., Marlow F., Chandrasekhar A., et al. Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nature Cell Biology 2002, 4:610-615.
46. Kai M., Heisenberg C.P., Tada M. Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation. Development 2008, 135:3043-3051.
47. Kane D.A., McFarland K.N., Warga R.M. Mutations in half baked/E-cadherin block cell behaviors that are necessary for teleost epiboly. Development 2005, 132:1105-1116.
48. Keller R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science 2002, 298:1950-1954.
49. Keller R., Danilchik M. Regional expression, pattern and timing of convergence and extension during gastrulation of Xenopus laevis. Development 1988, 103:193-209.
50. Kibar Z., Vogan K.J., Groulx N., Justice M.J., Underhill D.A., Gros P. Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nature Genetics 2001, 28:251-255.
51. Kilian B., Mansukoski H., Barbosa F.C., Ulrich F., Tada M., Heisenberg C.P. The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mechanisms of Development 2003, 120:467-476.
52. Kim G.H., Han J.K. Essential role for β-arrestin 2 in the regulation of Xenopus convergent extension movements. The EMBO Journal 2007, 26:2513-2526.
53. Kim S.K., Shindo A., Park T.J., Oh E.C., Ghosh S., Gray R.S., et al. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science 2010, 329:1337-1340.
54. Kinoshita N., Iioka H., Miyakoshi A., Ueno N. PKC δ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes & Development 2003, 17:1663-1676.
55. Kusakabe M., Nishida E. The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC. The EMBO Journal 2004, 23:4190-4201.
56. Lawrence P.A., Struhl G., Casal J. Do the protocadherins Fat and Dachsous link up to determine both planar cell polarity and the dimensions of organs?. Nature Cell Biology 2008, 10:1379-1382.
57. Lawrence P.A., Struhl G., Casal J. Planar cell polarity: A bridge too far?. Current Biology 2008, 18:R959-R961.
58. Lawson A., Schoenwolf G.C. Cell populations and morphogenetic movements underlying formation of the avian primitive streak and organizer. Genesis 2001, 29:188-195.
59. LeClair E.E., Mui S.R., Huang A., Topczewska J.M., Topczewski J. Craniofacial skeletal defects of adult zebrafish Glypican 4 (knypek) mutants. Developmental Dynamics 2009, 238:2550-2563.
60. Li S., Esterberg R., Lachance V., Ren D., Radde-Gallwitz K., Chi F., et al. Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:2264-2269.
61. Lin F., Sepich D.S., Chen S., Topczewski J., Yin C., Solnica-Krezel L., et al. Essential roles of Gα12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. The Journal of Cell Biology 2005, 169:777-787.
62. Lu X., Borchers A.G., Jolicoeur C., Rayburn H., Baker J.C., Tessier-Lavigne M. PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 2004, 430:93-98.
63. Mao Y., Mulvaney J., Zakaria S., Yu T., Morgan K.M., Allen S., et al. Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development 2011, 138:947-957.
64. Mapp O.M., Walsh G.S., Moens C.B., Tada M., Prince V.E. Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity. Development 2011, 138:2121-2132.
65. Mapp O.M., Wanner S.J., Rohrschneider M.R., Prince V.E. Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration. Developmental Dynamics 2010, 239:1596-1608.
66. Marlow F., Topczewski J., Sepich D., Solnica-Krezel L. Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements. Current Biology 2002, 12:876-884.
67. Matthews H.K., Marchant L., Carmona-Fontaine C., Kuriyama S., Larrain J., Holt M.R., et al. Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA. Development 2008, 135:1771-1780.
68. May-Simera H.L., Kai M., Hernandez V., Osborn D.P., Tada M., Beales P.L. Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Developmental Biology 2010, 345:215-225.
69. McKay R.M., Peters J.M., Graff J.M. The casein kinase I family: Roles in morphogenesis. Developmental Biology 2001, 235:378-387.
70. Medina A., Swain R.K., Kuerner K.M., Steinbeisser H. Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation. The EMBO Journal 2004, 23:3249-3258.
71. Migeotte I., Omelchenko T., Hall A., Anderson K.V. Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biology 2010, 8:e1000442.
72. Montcouquiol M., Rachel R.A., Lanford P.J., Copeland N.G., Jenkins N.A., Kelley M.W. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 2003, 423:173-177.
73. Montero J.A., Carvalho L., Wilsch-Brauninger M., Kilian B., Mustafa C., Heisenberg C.P. Shield formation at the onset of zebrafish gastrulation. Development 2005, 132:1187-1198.
74. Montero J.A., Kilian B., Chan J., Bayliss P.E., Heisenberg C.P. Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. Current Biology 2003, 13:1279-1289.
75. Munoz R., Moreno M., Oliva C., Orbenes C., Larrain J. Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos. Nature Cell Biology 2006, 8:492-500.
76. Murdoch J.N., Henderson D.J., Doudney K., Gaston-Massuet C., Phillips H.M., Paternotte C., et al. Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse. Human Molecular Genetics 2003, 12:87-98.
77. Murdoch J.N., Rachel R.A., Shah S., Beermann F., Stanier P., Mason C.A., et al. Circletail, a new mouse mutant with severe neural tube defects: Chromosomal localization and interaction with the loop-tail mutation. Genomics 2001, 78:55-63.
78. Narimatsu M., Bose R., Pye M., Zhang L., Miller B., Ching P., et al. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell 2009, 137:295-307.
79. Ninomiya H., Elinson R.P., Winklbauer R. Antero-posterior tissue polarity links mesoderm convergent extension to axial patterning. Nature 2004, 430:364-367.
80. Ohkawara B., Glinka A., Niehrs C. Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Developmental Cell 2011, 20:303-314.
81. Ohkawara B., Yamamoto T.S., Tada M., Ueno N. Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 2003, 130:2129-2138.
82. Oishi I., Suzuki H., Onishi N., Takada R., Kani S., Ohkawara B., et al. The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes to Cells 2003, 8:645-654.
83. Ossipova O., Dhawan S., Sokol S., Green J.B. Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Developmental Cell 2005, 8:829-841.
84. Oteiza P., Koppen M., Krieg M., Pulgar E., Farias C., Melo C., et al. Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development 2010, 137:3459-3468.
85. Park T.J., Haigo S.L., Wallingford J.B. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nature Genetics 2006, 38:303-311.
86. Park M., Moon R.T. The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nature Cell Biology 2002, 4:20-25.
87. Paudyal A., Damrau C., Patterson V.L., Ermakov A., Formstone C., Lalanne Z., et al. The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Developmental Biology 2010, 10:87.
88. Qu Y., Glasco D.M., Zhou L., Sawant A., Ravni A., Fritzsch B., et al. Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. The Journal of Neuroscience 2010, 30:9392-9401.
89. Quesada-Hernandez E., Caneparo L., Schneider S., Winkler S., Liebling M., Fraser S.E., et al. Stereotypical cell division orientation controls neural rod midline formation in zebrafish. Current Biology 2010, 20:1966-1972.
90. Rauch G.J., Hammerschmidt M., Blader P., Schauerte H.E., Strahle U., Ingham P.W., et al. Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor Symposia on Quantitative Biology 1997, 62:227-234.
91. Rogulja D., Rauskolb C., Irvine K.D. Morphogen control of wing growth through the Fat signaling pathway. Developmental Cell 2008, 15:309-321.
92. Ross A.J., May-Simera H., Eichers E.R., Kai M., Hill J., Jagger D.J., et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nature Genetics 2005, 37:1135-1140.
93. Saburi S., Hester I., Fischer E., Pontoglio M., Eremina V., Gessler M., et al. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nature Genetics 2008, 40:1010-1015.
94. Saburi S., Hester I., Goodrich L., McNeill H. Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity. Development 2012, 139:1806-1820.
95. Sasai N., Nakazawa Y., Haraguchi T., Sasai Y. The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements. Nature Cell Biology 2004, 6:741-748.
96. Schambony A., Wedlich D. Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. Developmental Cell 2007, 12:779-792.
97. Schlessinger K., McManus E.J., Hall A. Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity. The Journal of Cell Biology 2007, 178:355-361.
98. Schwarz-Romond T., Asbrand C., Bakkers J., Kuhl M., Schaeffer H.J., Huelsken J., et al. The ankyrin repeat protein Diversin recruits Casein kinase Ie{open} to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes & Development 2002, 16:2073-2084.
99. Segalen M., Johnston C.A., Martin C.A., Dumortier J.G., Prehoda K.E., David N.B., et al. The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish. Developmental Cell 2010, 19:740-752.
100. Sepich D.S., Calmelet C., Kiskowski M., Solnica-Krezel L. Initiation of convergence and extension movements of lateral mesoderm during zebrafish gastrulation. Developmental Dynamics 2005, 234:279-292.
101. Sepich D.S., Myers D.C., Short R., Topczewski J., Marlow F., Solnica-Krezel L. Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis 2000, 27:159-173.
102. Sepich D.S., Usmani M., Pawlicki S., Solnica-Krezel L. Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development 2011, 138:543-552.
103. Shih J., Keller R. Cell motility driving mediolateral intercalation in explants of Xenopus laevis. Development 1992, 116:901-914.
104. Shima Y., Kengaku M., Hirano T., Takeichi M., Uemura T. Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Developmental Cell 2004, 7:205-216.
105. Shimada Y., Yonemura S., Ohkura H., Strutt D., Uemura T. Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Developmental Cell 2006, 10:209-222.
106. Simons M., Gloy J., Ganner A., Bullerkotte A., Bashkurov M., Kronig C., et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nature Genetics 2005, 37:537-543.
107. Simons M., Mlodzik M. Planar cell polarity signaling: From fly development to human disease. Annual Review of Genetics 2008, 42:517-540.
108. Slusarski D.C., Corces V.G., Moon R.T. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 1997, 390:410-413.
109. Sokol S.Y. Analysis of Dishevelled signalling pathways during Xenopus development. Current Biology 1996, 6:1456-1467.
110. Srinivas S., Rodriguez T., Clements M., Smith J.C., Beddington R.S. Active cell migration drives the unilateral movements of the anterior visceral endoderm. Development 2004, 131:1157-1164.
111. Stockinger P., Maitre J.L., Heisenberg C.P. Defective neuroepithelial cell cohesion affects tangential branchiomotor neuron migration in the zebrafish neural tube. Development 2011, 138:4673-4683.
112. Tada M., Smith J.C. Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 2000, 127:2227-2238.
113. Tahinci E., Thorne C.A., Franklin J.L., Salic A., Christian K.M., Lee L.A., et al. Lrp6 is required for convergent extension during Xenopus gastrulation. Development 2007, 134:4095-4106.
114. Takeuchi M., Nakabayashi J., Sakaguchi T., Yamamoto T.S., Takahashi H., Takeda H., et al. The prickle-related gene in vertebrates is essential for gastrulation cell movements. Current Biology 2003, 13:674-679.
115. Tanegashima K., Zhao H., Dawid I.B. WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation. The EMBO Journal 2008, 27:606-617.
116. Tawk M., Araya C., Lyons D.A., Reugels A.M., Girdler G.C., Bayley P.R., et al. A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature 2007, 446:797-800.
117. Theveneau E., Marchant L., Kuriyama S., Gull M., Moepps B., Parsons M., et al. Collective chemotaxis requires contact-dependent cell polarity. Developmental Cell 2010, 19:39-53.
118. Topczewski J., Sepich D.S., Myers D.C., Walker C., Amores A., Lele Z., et al. The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Developmental Cell 2001, 1:251-264.
119. Tree D.R., Shulman J.M., Rousset R., Scott M.P., Gubb D., Axelrod J.D. Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 2002, 109:371-381.
120. Trichas G., Joyce B., Crompton L.A., Wilkins V., Clements M., Tada M., et al. Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm. PLoS Biology 2011, 9:e1001019.
121. Trichas G., Smith A.M., White N., Wilkins V., Watanabe T., Moore A., et al. Multi-cellular rosettes in the mouse visceral endoderm facilitate the ordered migration of anterior visceral endoderm cells. PLoS Biology 2012, 10:e1001256.
122. Ulrich F., Concha M.L., Heid P.J., Voss E., Witzel S., Roehl H., et al. Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development 2003, 130:5375-5384.
123. Ulrich F., Krieg M., Schotz E.M., Link V., Castanon I., Schnabel V., et al. Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Developmental Cell 2005, 9:555-564.
124. Unterseher F., Hefele J.A., Giehl K., De Robertis E.M., Wedlich D., Schambony A. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. The EMBO Journal 2004, 23:3259-3269.
125. Van Raay T.J., Coffey R.J., Solnica-Krezel L. Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling. Developmental Biology 2007, 309:151-168.
126. Veeman M.T., Slusarski D.C., Kaykas A., Louie S.H., Moon R.T. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Current Biology 2003, 13:680-685.
127. Vervenne H.B., Crombez K.R., Lambaerts K., Carvalho L., Koppen M., Heisenberg C.P., et al. Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Developmental Biology 2008, 320:267-277.
128. Voiculescu O., Bertocchini F., Wolpert L., Keller R.E., Stern C.D. The amniote primitive streak is defined by epithelial cell intercalation before gastrulation. Nature 2007, 449:1049-1052.
129. von der Hardt S., Bakkers J., Inbal A., Carvalho L., Solnica-Krezel L., Heisenberg C.P., et al. The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Current Biology 2007, 17:475-487.
130. Wada H., Iwasaki M., Sato T., Masai I., Nishiwaki Y., Tanaka H., et al. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development 2005, 132:2273-2285.
131. Wada H., Tanaka H., Nakayama S., Iwasaki M., Okamoto H. Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development 2006, 133:4749-4759.
132. Wallingford J., Mitchell B. Strange as it may seem: The many links between Wnt signaling, planar cell polarity, and cilia. Genes & Development 2011, 25:201-213.
133. Wallingford J.B., Rowning B.A., Vogeli K.M., Rothbacher U., Fraser S.E., Harland R.M. Dishevelled controls cell polarity during Xenopus gastrulation. Nature 2000, 405:81-85.
134. Walsh G.S., Grant P.K., Morgan J.A., Moens C.B. Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration. Development 2011, 138:3033-3042.
135. Wang Y., Guo N., Nathans J. The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. The Journal of Neuroscience 2006, 26:2147-2156.
136. Wang J., Hamblet N.S., Mark S., Dickinson M.E., Brinkman B.C., Segil N., et al. Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development 2006, 133:1767-1778.
137. Wang Y., Janicki P., Koster I., Berger C.D., Wenzl C., Grosshans J., et al. Xenopus Paraxial Protocadherin regulates morphogenesis by antagonizing Sprouty. Genes & Development 2008, 22:878-883.
138. Wang J., Mark S., Zhang X., Qian D., Yoo S.J., Radde-Gallwitz K., et al. Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nature Genetics 2005, 37:980-985.
139. Weber G.F., Bjerke M.A., DeSimone D.W. A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration. Developmental Cell 2012, 22:104-115.
140. Weiser D.C., Row R.H., Kimelman D. Rho-regulated myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation. Development 2009, 136:2375-2384.
141. Williams B.B., Cantrell V.A., Mundell N.A., Bennett A.C., Quick R.E., Jessen J.R. VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration. Journal of Cell Science 2012, 125:2141-2147.
142. Winklbauer R. Mesodermal cell migration during Xenopus gastrulation. Developmental Biology 1990, 142:155-168.
143. Witte F., Bernatik O., Kirchner K., Masek J., Mahl A., Krejci P., et al. Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2. The FASEB Journal 2010, 24:2417-2426.
144. Witzel S., Zimyanin V., Carreira-Barbosa F., Tada M., Heisenberg C.P. Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. The Journal of Cell Biology 2006, 175:791-802.
145. Yamaguchi T.P., Bradley A., McMahon A.P., Jones S. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 1999, 126:1211-1223.
146. Yamamoto S., Nishimura O., Misaki K., Nishita M., Minami Y., Yonemura S., et al. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Developmental Cell 2008, 15:23-36.
147. Yamamoto N., Okano T., Ma X., Adelstein R.S., Kelley M.W. Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development 2009, 136:1977-1986.
148. Yamanaka H., Moriguchi T., Masuyama N., Kusakabe M., Hanafusa H., Takada R., et al. JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Reports 2002, 3:69-75.
149. Yamanaka Y., Tamplin O.J., Beckers A., Gossler A., Rossant J. Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Developmental Cell 2007, 13:884-896.
150. Ybot-Gonzalez P., Savery D., Gerrelli D., Signore M., Mitchell C.E., Faux C.H., et al. Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure. Development 2007, 134:789-799.
151. Yen W.W., Williams M., Periasamy A., Conaway M., Burdsal C., Keller R., et al. PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation. Development 2009, 136:2039-2048.
152. Yin C., Kiskowski M., Pouille P.A., Farge E., Solnica-Krezel L. Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation. The Journal of Cell Biology 2008, 180:221-232.
153. Yu A., Rual J.F., Tamai K., Harada Y., Vidal M., He X., et al. Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Developmental Cell 2007, 12:129-141.
154. Zallen J.A., Wieschaus E. Patterned gene expression directs bipolar planar polarity in Drosophila. Developmental Cell 2004, 6:343-355.
155. Zigman M., Trinh le A., Fraser S.E., Moens C.B. Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions. Current Biology 2011, 21:79-86.