Planar cell polarity acts through septins to control collective cell movement and ciliogenesis

Science

Volumn 329, Issue 5997, 2010, Pages 1337-1340

  Kim, Su Kyoung ^a   Shindo, Asako ^a   Park, Tae Joo ^a,f   Oh, Edwin C ^b   Ghosh, Srimoyee ^a,g   Gray, Ryan S ^a,h   Lewis, Richard A ^c   Johnson, Colin A ^d   Attie Bittach, Tania ^e   Katsanis, Nicholas ^b   Wallingford, John B ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^h JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; NOTCH RECEPTOR; PROTEIN; PROTEIN FRITZ; SEPTIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

DISEASE INCIDENCE; EMBRYONIC DEVELOPMENT; FROG; MUTATION; PROTEIN; PUBLIC HEALTH;

ANIMAL CELL; ARTICLE; BARDET BIEDL SYNDROME; CELL ELONGATION; CELL MEMBRANE; CELL MOTION; CELL POLARITY; CILIOGENESIS; CONTROLLED STUDY; CYTOSKELETON; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; EUKARYOTIC FLAGELLUM; GENE MUTATION; MECKEL SYNDROME; MOLECULAR DYNAMICS; MORPHOGENESIS; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; VERTEBRATE; XENOPUS;

ABNORMALITIES, MULTIPLE; ANIMALS; BARDET-BIEDL SYNDROME; CELL MEMBRANE; CELL MOVEMENT; CELL POLARITY; CELL SHAPE; CILIA; CYTOSKELETAL PROTEINS; CYTOSKELETON; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GASTRULA; GENETIC ASSOCIATION STUDIES; GLYCOPROTEINS; GTP-BINDING PROTEINS; HEDGEHOG PROTEINS; HUMANS; MORPHOGENESIS; MUTANT PROTEINS; MUTATION; SEPTINS; SYNDROME; XENOPUS LAEVIS; XENOPUS PROTEINS;

VERTEBRATA;

EID: 77956505731     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1191184     Document Type: Article

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35. We thank P. Abitua for technical assistance; E. Spiliotis for the antibodies; and A. Ewald, B. Mitchell, E. Brooks, and K. Smith for critical discussions and reading. This work was supported by grants from the Uehara Memorial Foundation (A.S.); National Institute of General Medcial Science (NIH), March of Dimes, Burroughs Wellcome Fund, the Sandler Program for Asthma Research, and the Texas Advanced Research Program (J.B.W.); National Institute of Child Health and Human Development and National Institute of Digestive Diseases and Kidney Disease (NIH) (N.K.). N.K. is the George W. Brumley Professor. J.B.W. is an Early Career Scientist of the Howard Hughes Medical Institute.