Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity

Journal of Cell Biology

Volumn 174, Issue 2, 2006, Pages 301-313

  Chen, Xuejun ^a   Gumbiner, Barry M ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; C CADHERIN; CADHERIN; FRIZZLED PROTEIN; MUTANT PROTEIN; PARAXIAL PROTOCADHERIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL SELECTION; CELL TYPE; CONTROLLED STUDY; EMBRYO; GASTRULATION; MESODERM; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; XENOPUS LAEVIS;

ACTIVINS; ANIMALS; CADHERINS; CELL ADHESION; CHO CELLS; CRICETINAE; CRICETULUS; DOWN-REGULATION; EMBRYO, NONMAMMALIAN; GASTRULA; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MODELS, BIOLOGICAL; MORPHOGENESIS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SIGNAL TRANSDUCTION; XENOPUS; XENOPUS PROTEINS;

XENOPUS LAEVIS;

EID: 33746056119     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200602062     Document Type: Article

References (36)

1. Angst, B.D., C. Marcozzi, and A.I. Magee. 2001. The cadherin superfamily: diversity in form and function. J. Cell Sci. 114:629-641.
2. Bradley, R.S., A. Espeseth, and C. Kintner. 1998. NF-protocadherin, a novel member of the cadherin superfamily, is required for Xenopus ectodermal differentiation. Curr. Biol. 8:325-334.
3. Brieher, W.M., and B.M. Gumbiner. 1994. Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps. J. Cell Biol. 126:519-527.
4. Brieher, W.M., A.S. Yap, and B.M. Gumbiner. 1996. Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135:487-496.
5. Chappuis-Flament, S., E. Wong, L.D. Hicks, C.M. Kay, and B.M. Gumbiner. 2001. Multiple cadherin extracellular repeats mediate homophilic binding and adhesion. J. Cell Biol. 154:231-243.
6. Choi, Y.S., R. Sehgal, P. McCrea, and B. Gumbiner. 1990. A cadherin-like protein in eggs and cleaving embryos of Xenopus laevis is expressed in oocytes in response to progesterone. J. Cell Biol. 110:1575-1582.
7. Foty, R.A., and M.S. Steinberg. 2004. Cadherin-mediated cell-cell adhesion and tissue segregation in relation to malignancy. Int. J. Dev. Biol. 48:397-409.
8. Ginsberg, D., D. DeSimone, and B. Geiger. 1991. Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos. Development. 111:315-325.
9. Gumbiner, B.M. 2005. Regulation of cadherin-mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 6:622-634.
10. Gurdon, J.B. 1977. Methods for nuclear transplantation in amphibia. Methods Cell Biol. 16:125-139.
11. Heasman, J., D. Ginsberg, B. Geiger, K. Goldstone, T. Pratt, C. Yoshida-Noro, and C. Wylie. 1994. A functional test for maternally inherited cadherin in Xenopus shows its importance in cell adhesion at the blastula stage. Development. 120:49-57.
12. Hirano, S., Q. Yan, and S.T. Suzuki. 1999. Expression of a novel protocadherin, OL-protocadherin, in a subset of functional systems of the developing mouse brain. J. Neurosci. 19:995-1005.
13. Kim, S.H., A. Yamamoto, T. Bouwmeester, E. Agius, and E.M. Robertis. 1998. The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation. Development. 125:4681-4690.
14. Kim, S.H., W.C. Jen, E.M. De Robertis, and C. Kintner. 2000. The protocadherin PAPC establishes segmental boundaries during somitogenesis in Xenopus embryos. Curr. Biol. 10:821-830.
15. Kohmura, N., K. Senzaki, S. Hamada, N. Kai, R. Yasuda, M. Watanabe, H. Ishii, M. Yasuda, M. Mishina, and T. Yagi. 1998. Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 20:1137-1151.
16. Kuroda, H., M. Inui, K. Sugimoto, T. Hayata, and M. Asashima. 2002. Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus. Dev. Biol. 244:267-277.
17. Lee, C.H., and B.M. Gumbiner. 1995. Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin. Dev. Biol. 171:363-373.
18. Levi, G., D. Ginsberg, J.M. Girault, I. Sabanay, J.P. Thiery, and B. Geiger. 1991. EP-cadherin in muscles and epithelia of Xenopus laevis embryos. Development. 113:1335-1344.
19. Medina, A., R.K. Swain, K.M. Kuerner, and H. Steinbeisser. 2004. Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation. EMBO J. 23:3249-3258.
20. Newport, J., and M. Kirschner. 1982. A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage. Cell. 30:675-686.
21. Niessen, C.M., and B.M. Gumbiner. 2002. Cadherin-mediated cell sorting not determined by binding or adhesion specificity. J. Cell Biol. 156:389-399.
22. Nieuwkoop, P.D., and J. Faber. 1967. Normal table of Xenopus Laevis. Elsevier North-Holland Biomedical Press, Amsterdam. 282 pp.
23. Nollet, F., P. Kools, and F. van Roy. 2000. Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. J. Mol. Biol. 299:551-572.
24. Nose, A., A. Nagafuchi, and M. Takeichi. 1988. Expressed recombinant cadherins mediate cell sorting in model systems. Cell. 54:993-1001.
25. Sago, H., M. Kitagawa, S. Obata, N. Mori, S. Taketani, J.M. Rochelle, M.F. Seldin, M. Davidson, T. St John, and S.T. Suzuki. 1995. Cloning, expression, and chromosomal localization of a novel cadherin-related protein, protocadherin-3. Genomics. 29:631-640.
26. Sano, K., H. Tanihara, R.L. Heimark, S. Obata, M. Davidson, T. St John, S. Taketani, and S. Suzuki. 1993. Protocadherins: a large family of cadherin-related molecules in central nervous system. EMBO J. 12:2249-2256.
27. Steinberg, M.S. 1970. Does differential adhesion govern self-assembly processes in histogenesis? Equilibrium configurations and the emergence of a hierarchy among populations of embryonic cells. J. Exp. Zool. 173:395-433.
28. Sumanas, S., and S.C. Ekker. 2001. Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation. Genesis. 30:119-122.
29. Sumanas, S., P. Strege, J. Heasman, and S.C. Ekker. 2000. The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development. 127:1981-1990.
30. Suzuki, S.T. 2000. Recent progress in protocadherin research. Exp. Cell Res. 261:13-18.
31. Symes, K., and J.C. Smith. 1987. Gastrulation movements provide an early marker of mesoderm induction in Xenopus laevis. Development. 101:339-349.
32. Unterseher, F., J.A. Hefele, K. Giehl, E.M. De Robertis, D. Wedlich, and A. Schambony. 2004. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 23:3259-3269.
33. Yagi, T., and M. Takeichi. 2000. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev. 14:1169-1180.
34. Yoshida, K. 2003. Fibroblast cell shape and adhesion in vitro is altered by overexpression of the 7a and 7b isoforms of protocadherin 7, but not the 7c isoform. Cell. Mol. Biol. Lett. 8:735-741.
35. Yoshida, K., K. Yoshitomo-Nakagawa, N. Seki, M. Sasaki, and S. Sugano. 1998. Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily. Genomics. 49:458-461.
36. Zhong, Y., W.M. Brieher, and B.M. Gumbiner. 1999. Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody. J. Cell Biol. 144:351-359.