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Volumn 39, Issue 11, 2007, Pages 1350-1360

Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; KINESIN; PROTEASOME; T CELL FACTOR PROTEIN; WNT PROTEIN;

EID: 35648985644     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2007.12     Document Type: Article
Times cited : (340)

References (50)
  • 1
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan, C.Y. & Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781-810 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 2
    • 0041695485 scopus 로고    scopus 로고
    • A second canon: Functions and mechanisms of beta-catenin-independent Wnt signaling
    • Veeman, M.T., Axelrod, J.D. & Moon, R.T. A second canon: functions and mechanisms of beta-catenin-independent Wnt signaling. Dev. Cell 5, 367-377 (2003).
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 3
    • 0030978351 scopus 로고    scopus 로고
    • beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., Bauer, A., Stappert, J., Kispert, A. & Kemler, R. beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804 (1997).
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 4
    • 18244389736 scopus 로고    scopus 로고
    • Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is elevated in human colon tumors
    • Yan, D. et al. Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is elevated in human colon tumors. Proc. Natl. Acad. Sci. USA 98, 14973-14978 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14973-14978
    • Yan, D.1
  • 5
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho, E.H. et al. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 22, 1172-1183 (2002).
    • (2002) Mol. Cell. Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1
  • 6
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod, J.D., Miller, J.R., Shulman, J.M., Moon, R.T. & Perrimon, N. Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12, 2610-2622 (1998).
    • (1998) Genes Dev , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 7
    • 0032504052 scopus 로고    scopus 로고
    • Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    • Boutros, M., Paricio, N., Strutt, D.I. & Mlodzik, M. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94, 109-118 (1998).
    • (1998) Cell , vol.94 , pp. 109-118
    • Boutros, M.1    Paricio, N.2    Strutt, D.I.3    Mlodzik, M.4
  • 8
    • 0037032828 scopus 로고    scopus 로고
    • Shaping the vertebrate body plan by polarized embryonic cell movements
    • Keller, R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science 298, 1950-1954 (2002).
    • (2002) Science , vol.298 , pp. 1950-1954
    • Keller, R.1
  • 9
    • 4744352094 scopus 로고    scopus 로고
    • Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates
    • Torban, E., Kor, C. & Gros, P. Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates. Trends Genet. 20, 570-577 (2004).
    • (2004) Trends Genet , vol.20 , pp. 570-577
    • Torban, E.1    Kor, C.2    Gros, P.3
  • 10
    • 10744227509 scopus 로고    scopus 로고
    • Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse
    • Curtin, J.A. et al. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr. Biol. 13, 1129-1133 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 1129-1133
    • Curtin, J.A.1
  • 11
    • 0031979611 scopus 로고    scopus 로고
    • Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: A model of severe neural tube defects
    • Greene, N.D.E., Gerrelli, D., Van Straaten, H.W.M. & Copp, A.J. Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects. Mech. Dev. 73, 59-72 (1998).
    • (1998) Mech. Dev , vol.73 , pp. 59-72
    • Greene, N.D.E.1    Gerrelli, D.2    Van Straaten, H.W.M.3    Copp, A.J.4
  • 12
    • 0034931874 scopus 로고    scopus 로고
    • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant loop-tail
    • Kibar, Z. et al. Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant loop-tail. Nat. Genet. 28, 251-255 (2001).
    • (2001) Nat. Genet , vol.28 , pp. 251-255
    • Kibar, Z.1
  • 13
    • 0035868509 scopus 로고    scopus 로고
    • Identification of a new chemically induced allele (Lp(m1Jus)) at the loop-tail locus: Morphology, histology, and genetic mapping
    • Kibar, Z. et al. Identification of a new chemically induced allele (Lp(m1Jus)) at the loop-tail locus: Morphology, histology, and genetic mapping. Genomics 72, 331-337 (2001).
    • (2001) Genomics , vol.72 , pp. 331-337
    • Kibar, Z.1
  • 14
    • 0037991533 scopus 로고    scopus 로고
    • Identification of Vangl2 and Scrb1 as planar polarity genes in mammals
    • Montcouquiol, M. et al. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423, 173-177 (2003).
    • (2003) Nature , vol.423 , pp. 173-177
    • Montcouquiol, M.1
  • 15
    • 0242581681 scopus 로고    scopus 로고
    • Hedgehog signalling in the mouse requires intraflagellar transport proteins
    • Huangfu, D. et al. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426, 83-87 (2003).
    • (2003) Nature , vol.426 , pp. 83-87
    • Huangfu, D.1
  • 16
    • 26644460824 scopus 로고    scopus 로고
    • Vertebrate Smoothened functions at the primary cilium
    • Corbit, K.C. et al. Vertebrate Smoothened functions at the primary cilium. Nature 437, 1018-1021 (2005).
    • (2005) Nature , vol.437 , pp. 1018-1021
    • Corbit, K.C.1
  • 17
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu, A.M., Wang, B.L. & Niswander, L.A. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132, 3103-3111 (2005).
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.M.1    Wang, B.L.2    Niswander, L.A.3
  • 18
    • 27144460671 scopus 로고    scopus 로고
    • Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    • Ross, A.J. et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 37, 1135-1140 (2005).
    • (2005) Nat. Genet , vol.37 , pp. 1135-1140
    • Ross, A.J.1
  • 19
    • 31144478298 scopus 로고    scopus 로고
    • Dissection of epistasis in oligogenic Bardet-Biedl syndrome
    • Badano, J.L. et al. Dissection of epistasis in oligogenic Bardet-Biedl syndrome. Nature 439, 326-330 (2006).
    • (2006) Nature , vol.439 , pp. 326-330
    • Badano, J.L.1
  • 20
    • 0442272488 scopus 로고    scopus 로고
    • No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebra-fish
    • Marlow, F., Gonzalez, E.M., Yin, C.Y., Rojo, C. & Solnica-Krezel, L. No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebra-fish. Development 131, 203-216 (2004).
    • (2004) Development , vol.131 , pp. 203-216
    • Marlow, F.1    Gonzalez, E.M.2    Yin, C.Y.3    Rojo, C.4    Solnica-Krezel, L.5
  • 21
    • 0034604096 scopus 로고    scopus 로고
    • Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
    • Heisenberg, C.P. et al. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405, 76-81 (2000).
    • (2000) Nature , vol.405 , pp. 76-81
    • Heisenberg, C.P.1
  • 22
    • 0033600239 scopus 로고    scopus 로고
    • The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
    • Ishitani, T. et al. The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF. Nature 399, 798-802 (1999).
    • (1999) Nature , vol.399 , pp. 798-802
    • Ishitani, T.1
  • 23
    • 15744365467 scopus 로고    scopus 로고
    • The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning
    • Weidinger, G., Thorpe, C., Wuennenberg-Stapleton, K., Ngai, J. & Moon, R. The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning. Curr. Biol. 15, 489-500 (2005).
    • (2005) Curr. Biol , vol.15 , pp. 489-500
    • Weidinger, G.1    Thorpe, C.2    Wuennenberg-Stapleton, K.3    Ngai, J.4    Moon, R.5
  • 24
    • 0035370273 scopus 로고    scopus 로고
    • Neural induction in the absence of mesoderm: Beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus
    • Wessely, O., Agius, E., Oelgeschlager, M., Pera, E. & Robertis, E.D. Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus. Dev. Biol. 234, 161-173 (2001).
    • (2001) Dev. Biol , vol.234 , pp. 161-173
    • Wessely, O.1    Agius, E.2    Oelgeschlager, M.3    Pera, E.4    Robertis, E.D.5
  • 25
    • 11144358277 scopus 로고    scopus 로고
    • Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish
    • Nojima, H. et al. Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish. Mech. Dev. 121, 371-386 (2004).
    • (2004) Mech. Dev , vol.121 , pp. 371-386
    • Nojima, H.1
  • 26
    • 0014104888 scopus 로고
    • Flagellar regeneration in protozoan flagellates
    • Rosenbaum, J.L. & Child, F.M. Flagellar regeneration in protozoan flagellates. J. Cell Biol. 34, 345-364 (1967).
    • (1967) J. Cell Biol , vol.34 , pp. 345-364
    • Rosenbaum, J.L.1    Child, F.M.2
  • 27
    • 0344373791 scopus 로고    scopus 로고
    • Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements
    • Veeman, M.T., Slusarski, D.C., Kaykas, A., Louie, S.H. & Moon, R.T. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr. Biol. 13, 680-685 (2003).
    • (2003) Curr. Biol , vol.13 , pp. 680-685
    • Veeman, M.T.1    Slusarski, D.C.2    Kaykas, A.3    Louie, S.H.4    Moon, R.T.5
  • 28
    • 20244381625 scopus 로고    scopus 로고
    • The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
    • Kim, J.C. et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat. Genet. 36, 462-470 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 462-470
    • Kim, J.C.1
  • 29
    • 0030975671 scopus 로고    scopus 로고
    • -/- colon carcinoma
    • -/- colon carcinoma. Science 275, 1784-1787 (1997).
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1
  • 30
    • 0033609103 scopus 로고    scopus 로고
    • Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II
    • Marszalek, J.R., Ruiz-Lozano, P., Roberts, E., Chien, K.R. & Goldstein, L.S.B. Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc. Natl. Acad. Sci. USA 96, 5043-5048 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5043-5048
    • Marszalek, J.R.1    Ruiz-Lozano, P.2    Roberts, E.3    Chien, K.R.4    Goldstein, L.S.B.5
  • 31
    • 0030868934 scopus 로고    scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase: Nuclear translocation participates in neuronal and nonneuronal cell death
    • Sawa, A., Khan, A.A., Hester, L.D. & Snyder, S.H. Glyceraldehyde-3-phosphate dehydrogenase: Nuclear translocation participates in neuronal and nonneuronal cell death. Proc. Natl. Acad. Sci. USA 94, 11669-11674 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11669-11674
    • Sawa, A.1    Khan, A.A.2    Hester, L.D.3    Snyder, S.H.4
  • 32
    • 33846990139 scopus 로고    scopus 로고
    • Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling
    • Itoh, K., Brott, B.K., Bae, G.-U., Ratcliffe, M.J. & Sokol, S.Y. Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. J. Biol. 4, 1 (2005).
    • (2005) J. Biol , vol.4 , pp. 1
    • Itoh, K.1    Brott, B.K.2    Bae, G.-U.3    Ratcliffe, M.J.4    Sokol, S.Y.5
  • 33
    • 0027941483 scopus 로고
    • Regulated expression of Wnt family members during proliferation of C57mg mammary cells
    • Olson, D.J. & Papkoff, J. Regulated expression of Wnt family members during proliferation of C57mg mammary cells. Cell Growth Differ. 5, 197-206 (1994).
    • (1994) Cell Growth Differ , vol.5 , pp. 197-206
    • Olson, D.J.1    Papkoff, J.2
  • 34
    • 0031456662 scopus 로고    scopus 로고
    • Transformation by Wnt family proteins correlates with regulation of beta-catenin
    • Shimizu, H. et al. Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ. 8, 1349-1358 (1997).
    • (1997) Cell Growth Differ , vol.8 , pp. 1349-1358
    • Shimizu, H.1
  • 35
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
    • Slusarski, D.C., Corces, V. & Moon, R. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 390, 410-413 (1997).
    • (1997) Nature , vol.390 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.2    Moon, R.3
  • 36
    • 33646562887 scopus 로고    scopus 로고
    • Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)
    • Chiang, A.P. et al. Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc. Natl. Acad. Sci. USA 103, 6287-6292 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6287-6292
    • Chiang, A.P.1
  • 37
    • 0345593387 scopus 로고    scopus 로고
    • Dynamic association of proteasomal machinery with the centrosome
    • Wigley, W.C. et al. Dynamic association of proteasomal machinery with the centrosome. J. Cell Biol. 145, 481-490 (1999).
    • (1999) J. Cell Biol , vol.145 , pp. 481-490
    • Wigley, W.C.1
  • 38
    • 27644563785 scopus 로고    scopus 로고
    • Purification of PA700, the 19S regulatory subunit of the 26S proteasome
    • DeMartino, G.N. Purification of PA700, the 19S regulatory subunit of the 26S proteasome. Methods Enzymol. 398, 295-306 (2005).
    • (2005) Methods Enzymol , vol.398 , pp. 295-306
    • DeMartino, G.N.1
  • 40
    • 0028848212 scopus 로고
    • Molecular cloning and expression of a 26S proteasome subunit enriched in dileucine repeats
    • Deveraux, Q., Jensen, C. & Rechsteiner, M. Molecular cloning and expression of a 26S proteasome subunit enriched in dileucine repeats. J. Biol. Chem. 270, 23726-23729 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 23726-23729
    • Deveraux, Q.1    Jensen, C.2    Rechsteiner, M.3
  • 41
    • 33748335482 scopus 로고    scopus 로고
    • The ciliary proteome database: An integrated community resource for the genetic and functional dissection of cilia
    • Gherman, A., Davis, E. & Katsanis, N. The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia. Nat. Genet. 38, 961-962 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 961-962
    • Gherman, A.1    Davis, E.2    Katsanis, N.3
  • 42
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse, R. Wnt signaling in disease and in development. Cell Res. 15, 28-32 (2005).
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 43
    • 0037214344 scopus 로고    scopus 로고
    • 2+ pathway to antagonize Wnt/beta-catenin signaling
    • 2+ pathway to antagonize Wnt/beta-catenin signaling. Mol. Cell. Biol. 23, 131-139 (2003).
    • (2003) Mol. Cell. Biol , vol.23 , pp. 131-139
    • Ishitani, T.1
  • 44
    • 0345356929 scopus 로고    scopus 로고
    • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
    • Liang, H. et al. Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. Cancer Cell 4, 349-360 (2003).
    • (2003) Cancer Cell , vol.4 , pp. 349-360
    • Liang, H.1
  • 45
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • Mikels, A.J. & Nusse, R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 4, e115 (2006).
    • (2006) PLoS Biol , vol.4
    • Mikels, A.J.1    Nusse, R.2
  • 46
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation
    • Topol, L. et al. Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. J. Cell Biol. 162, 899-908 (2003).
    • (2003) J. Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1
  • 47
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signalling pathways
    • Simons, M. et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signalling pathways. Nat. Genet. 37, 537-543 (2005).
    • (2005) Nat. Genet , vol.37 , pp. 537-543
    • Simons, M.1
  • 48
    • 33745496759 scopus 로고    scopus 로고
    • The emerging complexity of the vertebrate cilium: New functional roles for an ancient organelle
    • Davis, E.E., Brueckner, M. & Katsanis, N. The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle. Dev. Cell 11, 9-19 (2006).
    • (2006) Dev. Cell , vol.11 , pp. 9-19
    • Davis, E.E.1    Brueckner, M.2    Katsanis, N.3
  • 49
    • 0027453569 scopus 로고
    • Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos
    • Thisse, C., Thisse, B., Schilling, T.F. & Postlethwait, J.H. Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos. Development 119, 1203-1215 (1993).
    • (1993) Development , vol.119 , pp. 1203-1215
    • Thisse, C.1    Thisse, B.2    Schilling, T.F.3    Postlethwait, J.H.4
  • 50
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • Willert, K. et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423, 448-452 (2003).
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1


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