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Volumn 7, Issue 2, 2011, Pages

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection

(21)  Ferrari, Guido a   Korber, Bette b   Goonetilleke, Nilu c   Liu, Michael K P c   Turnbull, Emma L d   Salazar Gonzalez, Jesus F e   Hawkins, Natalie f   Self, Steve f   Watson, Sydeaka b,g   Betts, Michael R h   Gay, Cynthia i   McGhee, Kara a   Pellegrino, Pierre j   Williams, Ian j   Tomaras, Georgia D a   Haynes, Barton F a   Gray, Clive M k   Borrow, Persephone d   Roederer, Mario l   McMichael, Andrew J c   more..


Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; INTERLEUKIN 2; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; EPITOPE;

EID: 79952213493     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001273     Document Type: Article
Times cited : (83)

References (57)
  • 1
    • 32944477067 scopus 로고    scopus 로고
    • The rational design of an AIDS vaccine
    • Douek DC, Kwong PD, Nabel GJ, (2006) The rational design of an AIDS vaccine. Cell 124: 677-681.
    • (2006) Cell , vol.124 , pp. 677-681
    • Douek, D.C.1    Kwong, P.D.2    Nabel, G.J.3
  • 2
    • 44949154503 scopus 로고    scopus 로고
    • CD8+ T cell efficacy in vaccination and disease
    • Appay V, Douek D, Price D, (2008) CD8+ T cell efficacy in vaccination and disease. Nat Med.
    • (2008) Nat Med
    • Appay, V.1    Douek, D.2    Price, D.3
  • 3
    • 0028041344 scopus 로고
    • Virus-specific CD8+ cytotoxic T lymphocyte activity associated with control viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MBA, (1994) Virus-specific CD8+ cytotoxic T lymphocyte activity associated with control viremia in primary human immunodeficiency virus type 1 infection. J Virol 68: 6103-6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.A.5
  • 4
    • 0028337166 scopus 로고
    • Temporal association of cellular immune response with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JF, Cao Y, Andrews CA, McLeod G, et al. (1994) Temporal association of cellular immune response with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68: 4650-4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.F.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5
  • 5
    • 0027979442 scopus 로고
    • Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope
    • Safrit JT, Andrews CA, Zhu T, Ho DD, Koup RA, (1994) Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope. J Exp Med 179: 463-472.
    • (1994) J Exp Med , vol.179 , pp. 463-472
    • Safrit, J.T.1    Andrews, C.A.2    Zhu, T.3    Ho, D.D.4    Koup, R.A.5
  • 6
    • 67449147145 scopus 로고    scopus 로고
    • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
    • Goonetilleke N, Liu MKP, Salazar-Gonzalez JF, Ferrari G, Giorgi E, et al. (2009) The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J Exp Med 206: 1253-1272.
    • (2009) J Exp Med , vol.206 , pp. 1253-1272
    • Goonetilleke, N.1    Liu, M.K.P.2    Salazar-Gonzalez, J.F.3    Ferrari, G.4    Giorgi, E.5
  • 7
    • 0025827529 scopus 로고
    • Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
    • Phillips RE, Rowland-Jones S, Nixon DF, Gotch FM, Edwards JP, et al. (1991) Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354: 453-459.
    • (1991) Nature , vol.354 , pp. 453-459
    • Phillips, R.E.1    Rowland-Jones, S.2    Nixon, D.F.3    Gotch, F.M.4    Edwards, J.P.5
  • 8
    • 16944365445 scopus 로고    scopus 로고
    • Antiviral pressure exerted by HIV-1-specific cytotoxic T limphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
    • Borrow P, Lewicki H, Wei X, Horwitz MS, Peffer N, et al. (1997) Antiviral pressure exerted by HIV-1-specific cytotoxic T limphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat Med 3: 205-217.
    • (1997) Nat Med , vol.3 , pp. 205-217
    • Borrow, P.1    Lewicki, H.2    Wei, X.3    Horwitz, M.S.4    Peffer, N.5
  • 10
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: implications for vaccine design
    • Goulder PJ, Watkins DI, (2004) HIV and SIV CTL escape: implications for vaccine design. Nat Rev Immunol 4: 630-640.
    • (2004) Nat Rev Immunol , vol.4 , pp. 630-640
    • Goulder, P.J.1    Watkins, D.I.2
  • 11
    • 16944366524 scopus 로고    scopus 로고
    • Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS
    • Goulder PJ, Phillips RE, Colbert RA, McAdam S, Ogg G, et al. (1997) Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nat Med 3: 212-217.
    • (1997) Nat Med , vol.3 , pp. 212-217
    • Goulder, P.J.1    Phillips, R.E.2    Colbert, R.A.3    McAdam, S.4    Ogg, G.5
  • 12
    • 3543113110 scopus 로고    scopus 로고
    • Immune Escape Precedes Breakthrough Human Immunodeficiency Virus Type 1 Viremia and Broadening of the Cytotoxic T-Lymphocyte Response in an HLA-B27-Positive Long-Term-Nonprogressing Child
    • Feeney ME, Tang Y, Roosevelt KA, Leslie AJ, McIntosh K, et al. (2004) Immune Escape Precedes Breakthrough Human Immunodeficiency Virus Type 1 Viremia and Broadening of the Cytotoxic T-Lymphocyte Response in an HLA-B27-Positive Long-Term-Nonprogressing Child. J Virol 78: 8927-8930.
    • (2004) J Virol , vol.78 , pp. 8927-8930
    • Feeney, M.E.1    Tang, Y.2    Roosevelt, K.A.3    Leslie, A.J.4    McIntosh, K.5
  • 13
    • 0034699512 scopus 로고    scopus 로고
    • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia [see comments]
    • Allen TM, O'Connor DH, Jing P, Dzuris JL, Mothe BR, et al. (2000) Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia [see comments]. Nature 407: 386-390.
    • (2000) Nature , vol.407 , pp. 386-390
    • Allen, T.M.1    O'Connor, D.H.2    Jing, P.3    Dzuris, J.L.4    Mothe, B.R.5
  • 14
    • 0036113306 scopus 로고    scopus 로고
    • Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection
    • O'Connor DH, Allen TM, Vogel TU, Jing P, DeSouza IP, et al. (2002) Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nat Med 8: 493-499.
    • (2002) Nat Med , vol.8 , pp. 493-499
    • O'Connor, D.H.1    Allen, T.M.2    Vogel, T.U.3    Jing, P.4    DeSouza, I.P.5
  • 15
    • 0037122796 scopus 로고    scopus 로고
    • Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
    • Barouch DH, Kunstman J, Kuroda MJ, Schmitz JE, Santra S, et al. (2002) Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415: 335-339.
    • (2002) Nature , vol.415 , pp. 335-339
    • Barouch, D.H.1    Kunstman, J.2    Kuroda, M.J.3    Schmitz, J.E.4    Santra, S.5
  • 16
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, Prado JG, Fry EE, Pfafferott K, Leslie A, et al. (2006) Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol 80: 3617-3623.
    • (2006) J Virol , vol.80 , pp. 3617-3623
    • Martinez-Picado, J.1    Prado, J.G.2    Fry, E.E.3    Pfafferott, K.4    Leslie, A.5
  • 17
    • 33845756711 scopus 로고    scopus 로고
    • Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution
    • Li B, Gladden AD, Altfeld M, Kaldor JM, Cooper DA, et al. (2007) Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution. J Virol 81: 193-201.
    • (2007) J Virol , vol.81 , pp. 193-201
    • Li, B.1    Gladden, A.D.2    Altfeld, M.3    Kaldor, J.M.4    Cooper, D.A.5
  • 18
    • 39149111272 scopus 로고    scopus 로고
    • Identification and characterization of HIV-1 CD8+ T cell escape variants with impaired fitness
    • Sanchez-Merino V, Farrow MA, Brewster F, Somasundaran M, Luzuriaga K, (2008) Identification and characterization of HIV-1 CD8+ T cell escape variants with impaired fitness. J Infect Dis 197: 300-308.
    • (2008) J Infect Dis , vol.197 , pp. 300-308
    • Sanchez-Merino, V.1    Farrow, M.A.2    Brewster, F.3    Somasundaran, M.4    Luzuriaga, K.5
  • 19
    • 62749167015 scopus 로고    scopus 로고
    • Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein
    • Boutwell CL, Rowley CF, Essex M, (2009) Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein. J Virol 83: 2460-2468.
    • (2009) J Virol , vol.83 , pp. 2460-2468
    • Boutwell, C.L.1    Rowley, C.F.2    Essex, M.3
  • 20
    • 33645772992 scopus 로고    scopus 로고
    • Estimating costs and benefits of CTL escape mutations in SIV/HIV infection
    • Ganusov V, de Boer R, (2006) Estimating costs and benefits of CTL escape mutations in SIV/HIV infection. PLoS Comput Biol.
    • (2006) PLoS Comput Biol
    • Ganusov, V.1    de Boer, R.2
  • 21
    • 34248355554 scopus 로고    scopus 로고
    • In vivo fitness costs of different Gag CD8 T-cell escape mutant simian-human immunodeficiency viruses for macaques
    • Loh L, Batten CJ, Petravic J, Davenport MP, Kent SJ, (2007) In vivo fitness costs of different Gag CD8 T-cell escape mutant simian-human immunodeficiency viruses for macaques. J Virol 81: 5418-5422.
    • (2007) J Virol , vol.81 , pp. 5418-5422
    • Loh, L.1    Batten, C.J.2    Petravic, J.3    Davenport, M.P.4    Kent, S.J.5
  • 22
    • 18844454267 scopus 로고    scopus 로고
    • HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells
    • Zimmerli SC, Harari A, Cellerai C, Vallelian F, Bart PA, et al. (2005) HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proc Natl Acad Sci U S A 102: 7239-7244.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7239-7244
    • Zimmerli, S.C.1    Harari, A.2    Cellerai, C.3    Vallelian, F.4    Bart, P.A.5
  • 23
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781-4789.
    • (2006) Blood , vol.107 , pp. 4781-4789
    • Betts, M.R.1    Nason, M.C.2    West, S.M.3    De Rosa, S.C.4    Migueles, S.A.5
  • 24
    • 77957901912 scopus 로고    scopus 로고
    • Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-deep Sequencing
    • Fisher W, Ganusov V, Giorgi E, Hraber P, Keele BF, et al. (2010) Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-deep Sequencing. PLoS One.
    • (2010) PLoS One
    • Fisher, W.1    Ganusov, V.2    Giorgi, E.3    Hraber, P.4    Keele, B.F.5
  • 25
    • 65249183455 scopus 로고    scopus 로고
    • Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point
    • Burgers WA, Riou C, Mlotshwa M, Maenetje P, de Assis Rosa D, et al. (2009) Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point. J Immunol 182: 4751-4761.
    • (2009) J Immunol , vol.182 , pp. 4751-4761
    • Burgers, W.A.1    Riou, C.2    Mlotshwa, M.3    Maenetje, P.4    de Assis Rosa, D.5
  • 26
    • 67449119122 scopus 로고    scopus 로고
    • Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection
    • Turnbull EL, Wong M, Wang S, Wei X, Jones NA, et al. (2009) Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection. J Immunol 182: 7131-7145.
    • (2009) J Immunol , vol.182 , pp. 7131-7145
    • Turnbull, E.L.1    Wong, M.2    Wang, S.3    Wei, X.4    Jones, N.A.5
  • 27
    • 56649114351 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis
    • McElrath MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, et al. (2008) HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 372: 1894-1905.
    • (2008) Lancet , vol.372 , pp. 1894-1905
    • McElrath, M.J.1    De Rosa, S.C.2    Moodie, Z.3    Dubey, S.4    Kierstead, L.5
  • 29
    • 58149136160 scopus 로고    scopus 로고
    • Post-step modifications for research on HIV vaccines
    • Corey L, McElrath MJ, Kublin JG, (2009) Post-step modifications for research on HIV vaccines. AIDS 23: 3-8.
    • (2009) AIDS , vol.23 , pp. 3-8
    • Corey, L.1    McElrath, M.J.2    Kublin, J.G.3
  • 30
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu J, O'Brien KL, Lynch DM, Simmons NL, La Porte A, et al. (2009) Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457: 87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.1    O'Brien, K.L.2    Lynch, D.M.3    Simmons, N.L.4    La Porte, A.5
  • 31
    • 58149143041 scopus 로고    scopus 로고
    • Macaques vaccinated with live-attenuated SIV control replication of heterologous virus
    • Reynolds MR, Weiler AM, Weisgrau KL, Piaskowski SM, Furlott JR, et al. (2008) Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. J Exp Med 205: 2537-2550.
    • (2008) J Exp Med , vol.205 , pp. 2537-2550
    • Reynolds, M.R.1    Weiler, A.M.2    Weisgrau, K.L.3    Piaskowski, S.M.4    Furlott, J.R.5
  • 32
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen SG, Vieville C, Whizin N, Coyne-Johnson L, Siess DC, et al. (2009) Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat Med 15: 293-299.
    • (2009) Nat Med , vol.15 , pp. 293-299
    • Hansen, S.G.1    Vieville, C.2    Whizin, N.3    Coyne-Johnson, L.4    Siess, D.C.5
  • 34
    • 55849125074 scopus 로고    scopus 로고
    • Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status
    • Critchfield JW, Young DH, Hayes TL, Braun JV, Garcia JC, et al. (2008) Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. PLoS ONE 3: e3577.
    • (2008) PLoS ONE , vol.3
    • Critchfield, J.W.1    Young, D.H.2    Hayes, T.L.3    Braun, J.V.4    Garcia, J.C.5
  • 35
    • 44449096577 scopus 로고    scopus 로고
    • Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells
    • Streeck H, Brumme ZL, Anastario M, Cohen KW, Jolin JS, et al. (2008) Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells. PLoS Med 5: e100.
    • (2008) PLoS Med , vol.5
    • Streeck, H.1    Brumme, Z.L.2    Anastario, M.3    Cohen, K.W.4    Jolin, J.S.5
  • 36
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8 T cells leads to reversible immune dysfunction
    • Trautmann L, Janbazian L, Chomont N, Said E, (2006) Upregulation of PD-1 expression on HIV-specific CD8 T cells leads to reversible immune dysfunction. Nat Med.
    • (2006) Nat Med
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3    Said, E.4
  • 37
    • 33749338938 scopus 로고    scopus 로고
    • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    • Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, et al. (2006) PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med 203: 2281-2292.
    • (2006) J Exp Med , vol.203 , pp. 2281-2292
    • Petrovas, C.1    Casazza, J.P.2    Brenchley, J.M.3    Price, D.A.4    Gostick, E.5
  • 38
    • 34250327922 scopus 로고    scopus 로고
    • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
    • Precopio ML, Betts MR, Parrino J, Price DA, Gostick E, et al. (2007) Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 204: 1405-1416.
    • (2007) J Exp Med , vol.204 , pp. 1405-1416
    • Precopio, M.L.1    Betts, M.R.2    Parrino, J.3    Price, D.A.4    Gostick, E.5
  • 39
    • 50949117244 scopus 로고    scopus 로고
    • Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection
    • Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, et al. (2008) Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol 82: 9216-9227.
    • (2008) J Virol , vol.82 , pp. 9216-9227
    • Brumme, Z.L.1    Brumme, C.J.2    Carlson, J.3    Streeck, H.4    John, M.5
  • 40
    • 0032543212 scopus 로고    scopus 로고
    • Protective immunity does not correlate with the hierarchy of virus- specific cytotoxic T cell responses to naturally processed peptides
    • Gallimore A, Dumrese T, Hengartner H, Zinkernagel RM, Rammensee HG, (1998) Protective immunity does not correlate with the hierarchy of virus- specific cytotoxic T cell responses to naturally processed peptides. J Exp Med 187: 1647-1657.
    • (1998) J Exp Med , vol.187 , pp. 1647-1657
    • Gallimore, A.1    Dumrese, T.2    Hengartner, H.3    Zinkernagel, R.M.4    Rammensee, H.G.5
  • 41
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
    • (2007) J Exp Med , vol.204 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5
  • 42
    • 67650581553 scopus 로고    scopus 로고
    • Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
    • Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, et al. (2009) Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113: 6351-6360.
    • (2009) Blood , vol.113 , pp. 6351-6360
    • Almeida, J.R.1    Sauce, D.2    Price, D.A.3    Papagno, L.4    Shin, S.Y.5
  • 43
    • 65549116509 scopus 로고    scopus 로고
    • Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection
    • Price DA, Asher TE, Wilson NA, Nason MC, Brenchley JM, et al. (2009) Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection. J Exp Med 206: 923-936.
    • (2009) J Exp Med , vol.206 , pp. 923-936
    • Price, D.A.1    Asher, T.E.2    Wilson, N.A.3    Nason, M.C.4    Brenchley, J.M.5
  • 45
    • 77951489485 scopus 로고    scopus 로고
    • Phenotypic and Functional Profile of HIV-inhibitory CD8 T cells Elicited by Natural Infection and Heterologous Prime/boost Vaccination
    • Freel SA, Lamoreaux L, Chattopadhyay PK, Saunders K, Zarkowsky D, et al. (2010) Phenotypic and Functional Profile of HIV-inhibitory CD8 T cells Elicited by Natural Infection and Heterologous Prime/boost Vaccination. J Virol.
    • (2010) J Virol
    • Freel, S.A.1    Lamoreaux, L.2    Chattopadhyay, P.K.3    Saunders, K.4    Zarkowsky, D.5
  • 46
    • 0029417004 scopus 로고
    • Identification of RANTES, MIP-1αand MIP-1β as the major HIV-suppressive factors produced by CD8+ T cells
    • Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, et al. (1995) Identification of RANTES, MIP-1αand MIP-1β as the major HIV-suppressive factors produced by CD8+ T cells. Science 270: 1811-1815.
    • (1995) Science , vol.270 , pp. 1811-1815
    • Cocchi, F.1    DeVico, A.L.2    Garzino-Demo, A.3    Arya, S.K.4    Gallo, R.C.5
  • 47
    • 78649951742 scopus 로고    scopus 로고
    • Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage
    • Saunders KO, Ward-Caviness C, Schutte RJ, Freel SA, Overman RG, et al. (2010) Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage. Cellular immunology.
    • (2010) Cellular Immunology
    • Saunders, K.O.1    Ward-Caviness, C.2    Schutte, R.J.3    Freel, S.A.4    Overman, R.G.5
  • 48
    • 77955517958 scopus 로고    scopus 로고
    • Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication
    • Saunders KO, Freel SA, Overman RG, Cunningham CK, Tomaras GD, (2010) Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication. Virology 405: 234-242.
    • (2010) Virology , vol.405 , pp. 234-242
    • Saunders, K.O.1    Freel, S.A.2    Overman, R.G.3    Cunningham, C.K.4    Tomaras, G.D.5
  • 49
    • 77649193824 scopus 로고    scopus 로고
    • In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells
    • Wong JK, Strain MC, Porrata R, Reay E, Sankaran-Walters S, et al. (2010) In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells. PLoS Pathog 6: e1000748.
    • (2010) PLoS Pathog , vol.6
    • Wong, J.K.1    Strain, M.C.2    Porrata, R.3    Reay, E.4    Sankaran-Walters, S.5
  • 50
    • 77649217418 scopus 로고    scopus 로고
    • CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells
    • Klatt NR, Shudo E, Ortiz AM, Engram JC, Paiardini M, et al. (2010) CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells. PLoS Pathog 6: e1000747.
    • (2010) PLoS Pathog , vol.6
    • Klatt, N.R.1    Shudo, E.2    Ortiz, A.M.3    Engram, J.C.4    Paiardini, M.5
  • 51
    • 20144374940 scopus 로고    scopus 로고
    • CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides
    • Bansal A, Gough E, Sabbaj S, Ritter D, Yusim K, et al. (2005) CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides. AIDS 19: 241-250.
    • (2005) AIDS , vol.19 , pp. 241-250
    • Bansal, A.1    Gough, E.2    Sabbaj, S.3    Ritter, D.4    Yusim, K.5
  • 52
    • 9244254245 scopus 로고    scopus 로고
    • Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response
    • Jones NA, Wei X, Flower DR, Wong M, Michor F, et al. (2004) Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response. J Exp Med 200: 1243-1256.
    • (2004) J Exp Med , vol.200 , pp. 1243-1256
    • Jones, N.A.1    Wei, X.2    Flower, D.R.3    Wong, M.4    Michor, F.5
  • 53
    • 0041828179 scopus 로고    scopus 로고
    • Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection
    • Fiebig EW, Wright DJ, Rawal BD, Garrett PE, Schumacher RT, et al. (2003) Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS 17: 1871-1879.
    • (2003) AIDS , vol.17 , pp. 1871-1879
    • Fiebig, E.W.1    Wright, D.J.2    Rawal, B.D.3    Garrett, P.E.4    Schumacher, R.T.5
  • 54
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, et al. (2009) Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med 206: 1273-1289.
    • (2009) J Exp Med , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1    Salazar, M.G.2    Keele, B.F.3    Learn, G.H.4    Giorgi, E.E.5
  • 55
    • 84856043672 scopus 로고
    • A mathematical Theory of Communication
    • Shannon CE, (1948) A mathematical Theory of Communication. Bell System Technical Journal 27: 379-423, 623-656.
    • (1948) Bell System Technical Journal , vol.27
    • Shannon, C.E.1
  • 57
    • 0028046638 scopus 로고
    • Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences
    • Korber BT, Kunstman KJ, Patterson BK, Furtado M, McEvilly MM, et al. (1994) Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences. J Virol 68: 7467-7481.
    • (1994) J Virol , vol.68 , pp. 7467-7481
    • Korber, B.T.1    Kunstman, K.J.2    Patterson, B.K.3    Furtado, M.4    McEvilly, M.M.5


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