Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  He, Chengwei ^a,d   Qu, Xiying ^a   Wan, Jianbo ^a   Rong, Rong ^a   Huang, Lili ^a   Cai, Chun ^b   Zhou, Keyuan ^b   Gu, Yan ^c   Qian, Steven Y ^c   Kang, Jing X ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c NORTH DAKOTA STATE UNIVERSITY   (United States)

^d University of Macau   (Macao)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 2; CYTOCHROME P450; ICOSANOID; ICOSATRIENOIC ACID; LINOLEOYL COENZYME A DESATURASE; LIPOXYGENASE; MESSENGER RNA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTAGLANDIN D2; PROSTAGLANDIN E2; SAFFLOWER OIL;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME INHIBITION; GAS CHROMATOGRAPHY; INFLAMMATION; LEWIS CARCINOMA; LIPID COMPOSITION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MELANOMA; MICROVASCULATURE; MOUSE; NONHUMAN; RNA INTERFERENCE; SAFFLOWER; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VOLUME; UPREGULATION;

ANIMALS; EICOSANOIDS; ENZYME INHIBITORS; FEMALE; GENETIC THERAPY; LINOLEOYL-COA DESATURASE; LUNG; LUNG NEOPLASMS; MELANOMA; MICE; MICE, INBRED C57BL; RNA INTERFERENCE; RNA, SMALL INTERFERING; UP-REGULATION;

MUS;

EID: 84868118479     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047567     Document Type: Article

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