-
1
-
-
79952432817
-
Cancer drugs: remedy required
-
Editorial
-
Editorial (2011) Cancer drugs: remedy required. Nature 17: 231-232.
-
(2011)
Nature
, vol.17
, pp. 231-232
-
-
-
2
-
-
79952409338
-
Targeting the missing links for cancer therapy
-
Polyak K, Garber J, (2011) Targeting the missing links for cancer therapy. Nat Med 17: 283-284.
-
(2011)
Nat Med
, vol.17
, pp. 283-284
-
-
Polyak, K.1
Garber, J.2
-
3
-
-
79952366279
-
Metabolism unhinged: IDH mutations in cancer
-
Prensner JR, Chinnaiyan AM, (2011) Metabolism unhinged: IDH mutations in cancer. Nat Med 17: 291-293.
-
(2011)
Nat Med
, vol.17
, pp. 291-293
-
-
Prensner, J.R.1
Chinnaiyan, A.M.2
-
4
-
-
79952392467
-
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
-
Bissell MJ, Hines WC, (2011) Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med 17: 320-329.
-
(2011)
Nat Med
, vol.17
, pp. 320-329
-
-
Bissell, M.J.1
Hines, W.C.2
-
5
-
-
77649179672
-
Eicosanoids and cancer
-
Wang D, DuBois RN, (2010) Eicosanoids and cancer. Nat Rev Cancer 10: 181-193.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 181-193
-
-
Wang, D.1
DuBois, R.N.2
-
6
-
-
23844478668
-
Rethinking lipid mediators in physiology and pathophysiology
-
Weylandt KH, Kang JX, (2005) Rethinking lipid mediators in physiology and pathophysiology. Lancet 366: 618-620.
-
(2005)
Lancet
, vol.366
, pp. 618-620
-
-
Weylandt, K.H.1
Kang, J.X.2
-
7
-
-
58149292278
-
Modulation of inflammatory cytokines by omega-3 Fatty acids
-
Kang JX, Weylandt KH, (2008) Modulation of inflammatory cytokines by omega-3 Fatty acids. Subcell Biochem 49: 133-143.
-
(2008)
Subcell Biochem
, vol.49
, pp. 133-143
-
-
Kang, J.X.1
Weylandt, K.H.2
-
8
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarinomas
-
Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, et al. (1994) Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarinomas. Gastroenterology 107: 1183-1188.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
-
9
-
-
32544442362
-
COX inhibitors and breast cancer
-
Mazhar D, Ang R, Waxman J, (2006) COX inhibitors and breast cancer. Br J Cancer 94: 346-350.
-
(2006)
Br J Cancer
, vol.94
, pp. 346-350
-
-
Mazhar, D.1
Ang, R.2
Waxman, J.3
-
10
-
-
23844547173
-
15(S)-Hydroxyeicosatetraenoic acid induces angiogenesisvia activation of PI3K-Akt-mTOR-S6K1 signaling
-
Zhang B, Cao H, Rao GN, (2005) 15(S)-Hydroxyeicosatetraenoic acid induces angiogenesisvia activation of PI3K-Akt-mTOR-S6K1 signaling. Cancer Res 65: 7283-7291.
-
(2005)
Cancer Res
, vol.65
, pp. 7283-7291
-
-
Zhang, B.1
Cao, H.2
Rao, G.N.3
-
11
-
-
34547092185
-
Cytochrome p450 epoxygenase promotes human cancer metastasis
-
Jiang JG, Ning YG, Chen C, Ma D, Liu ZJ, et al. (2007) Cytochrome p450 epoxygenase promotes human cancer metastasis. Cancer Res 67: 6665-6674.
-
(2007)
Cancer Res
, vol.67
, pp. 6665-6674
-
-
Jiang, J.G.1
Ning, Y.G.2
Chen, C.3
Ma, D.4
Liu, Z.J.5
-
12
-
-
79953055619
-
Chemoprevention: First line of defence
-
Gravitz L, (2011) Chemoprevention: First line of defence. Nature 471: S5-S7.
-
(2011)
Nature
, vol.471
-
-
Gravitz, L.1
-
13
-
-
0023276149
-
A new era for science in nutrition
-
Leaf A, Weber PC, (1987) A new era for science in nutrition. Am J Clin Nutr 45: 1048-1053.
-
(1987)
Am J Clin Nutr
, vol.45
, pp. 1048-1053
-
-
Leaf, A.1
Weber, P.C.2
-
14
-
-
46449123205
-
The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
-
Simopoulos AP, (2008) The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med 233: 674-688.
-
(2008)
Exp Biol Med
, vol.233
, pp. 674-688
-
-
Simopoulos, A.P.1
-
15
-
-
18144454187
-
A simplified method for analysis of polyunsaturated fatty acids
-
Kang JX, Wang J, (2005) A simplified method for analysis of polyunsaturated fatty acids. BMC Biochem 6: 5.
-
(2005)
BMC Biochem
, vol.6
, pp. 5
-
-
Kang, J.X.1
Wang, J.2
-
16
-
-
0037134709
-
Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us
-
Hlatky L, Hahnfeldt P, Folkman J, (2002) Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 94: 883-893.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 883-893
-
-
Hlatky, L.1
Hahnfeldt, P.2
Folkman, J.3
-
17
-
-
0030057431
-
A quantitative assay using basement membrane extracts to study tumor angiogenesis in vivo
-
Ito Y, Iwamoto Y, Tanaka K, Okuyama K, Sugioka Y, (1996) A quantitative assay using basement membrane extracts to study tumor angiogenesis in vivo. Int J Cancer 67: 148-152.
-
(1996)
Int J Cancer
, vol.67
, pp. 148-152
-
-
Ito, Y.1
Iwamoto, Y.2
Tanaka, K.3
Okuyama, K.4
Sugioka, Y.5
-
18
-
-
0032929070
-
Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase
-
Cho HP, Nakamura MT, Clarke SD, (1999) Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase. J Biol Chem 274: 471-477.
-
(1999)
J Biol Chem
, vol.274
, pp. 471-477
-
-
Cho, H.P.1
Nakamura, M.T.2
Clarke, S.D.3
-
19
-
-
0032219604
-
Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice
-
Obukowicz MG, Welsch DJ, Salsgiver WJ, Martin-Berger CL, Chinn KS, et al. (1998) Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther 287: 157-166.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 157-166
-
-
Obukowicz, M.G.1
Welsch, D.J.2
Salsgiver, W.J.3
Martin-Berger, C.L.4
Chinn, K.S.5
-
20
-
-
0032819001
-
Essential fatty acids in health and chronic disease
-
Simopoulos AP, (1999) Essential fatty acids in health and chronic disease. Am J Clin Nutr 70: 560S-569S.
-
(1999)
Am J Clin Nutr
, vol.70
-
-
Simopoulos, A.P.1
-
21
-
-
80052052129
-
The Omega-6/Omega-3 Fatty Acid Ratio in Chronic Diseases: Animal Models and Molecular Aspects
-
Kang JX, (2011) The Omega-6/Omega-3 Fatty Acid Ratio in Chronic Diseases: Animal Models and Molecular Aspects. World Rev Nutr Diet 102: 22-29.
-
(2011)
World Rev Nutr Diet
, vol.102
, pp. 22-29
-
-
Kang, J.X.1
-
22
-
-
67650938102
-
The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential
-
Spencer L, Mann C, Metcalfe M, Webb M, Pollard C, et al. (2009) The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential. Eur J Cancer 45: 2077-2086.
-
(2009)
Eur J Cancer
, vol.45
, pp. 2077-2086
-
-
Spencer, L.1
Mann, C.2
Metcalfe, M.3
Webb, M.4
Pollard, C.5
-
23
-
-
27244445146
-
Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults
-
Burdge GC, Calder PC, (2005) Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod Nutr Dev 45: 581-597.
-
(2005)
Reprod Nutr Dev
, vol.45
, pp. 581-597
-
-
Burdge, G.C.1
Calder, P.C.2
-
24
-
-
0033215186
-
Differential Metabolism of Exogenous and Endogenous Arachidonic Acid in Human Neutrophils
-
Sala A, Zarini S, Folco G, Murphy RC, Henson PM, (1999) Differential Metabolism of Exogenous and Endogenous Arachidonic Acid in Human Neutrophils. J Biol Chem 274: 28264-28269.
-
(1999)
J Biol Chem
, vol.274
, pp. 28264-28269
-
-
Sala, A.1
Zarini, S.2
Folco, G.3
Murphy, R.C.4
Henson, P.M.5
-
25
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
Sun L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, et al. (2006) Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 9: 287-300.
-
(2006)
Cancer Cell
, vol.9
, pp. 287-300
-
-
Sun, L.1
Hui, A.M.2
Su, Q.3
Vortmeyer, A.4
Kotliarov, Y.5
-
26
-
-
2542454682
-
Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
-
Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, et al. (2004) Different gene expression patterns in invasive lobular and ductal carcinomas of the breast. Mol Biol Cell 15: 2523-2536.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2523-2536
-
-
Zhao, H.1
Langerød, A.2
Ji, Y.3
Nowels, K.W.4
Nesland, J.M.5
-
28
-
-
39549117982
-
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1
-
Furuta E, Pai SK, Zhan R, Bandyopadhyay S, Watabe M, et al. (2008) Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1. Cancer Res 68: 1003-1011.
-
(2008)
Cancer Res
, vol.68
, pp. 1003-1011
-
-
Furuta, E.1
Pai, S.K.2
Zhan, R.3
Bandyopadhyay, S.4
Watabe, M.5
-
29
-
-
0034718771
-
Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
-
Swinnen JV, Heemers H, Deboel L, Foufelle F, Heyns W, et al. (2000) Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene 19: 5173-5181.
-
(2000)
Oncogene
, vol.19
, pp. 5173-5181
-
-
Swinnen, J.V.1
Heemers, H.2
Deboel, L.3
Foufelle, F.4
Heyns, W.5
-
30
-
-
0037168955
-
Selective inhibition of Delta-6 desaturase impedes intestinal tumorigenesis
-
Hansen-Petrik MB, McEntee MF, Johnson BT, Obukowicz MG, Masferrer J, et al. (2002) Selective inhibition of Delta-6 desaturase impedes intestinal tumorigenesis. Cancer Lett 175: 157-163.
-
(2002)
Cancer Lett
, vol.175
, pp. 157-163
-
-
Hansen-Petrik, M.B.1
McEntee, M.F.2
Johnson, B.T.3
Obukowicz, M.G.4
Masferrer, J.5
-
31
-
-
0035976575
-
Prostaglandins and leukotrienes: advances in eicosanoid biology
-
Funk CD, (2001) Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294: 1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
32
-
-
38549162640
-
Inflammation, inflammatory cells and angiogenesis: decisions and indecisions
-
Noonan DM, De Lerma Barbaro A, Vannini N, Mortara L, Albini A, (2008) Inflammation, inflammatory cells and angiogenesis: decisions and indecisions. Cancer Metastasis Rev 27: 31-40.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 31-40
-
-
Noonan, D.M.1
de Lerma Barbaro, A.2
Vannini, N.3
Mortara, L.4
Albini, A.5
-
33
-
-
33751504296
-
Leukocytes, inflammation, and angiogenesis in cancer: fatal attractions
-
Ruegg C, (2006) Leukocytes, inflammation, and angiogenesis in cancer: fatal attractions. J Leukoc Biol 80: 682-684.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 682-684
-
-
Ruegg, C.1
-
34
-
-
34548150402
-
Angiogenesis and chronic inflammation: cause or consequence?
-
Costa C, Incio J, Soares R, (2007) Angiogenesis and chronic inflammation: cause or consequence? Angiogenesis 10: 149-166.
-
(2007)
Angiogenesis
, vol.10
, pp. 149-166
-
-
Costa, C.1
Incio, J.2
Soares, R.3
-
35
-
-
54249155141
-
Prostaglandin E2 regulates tumor angiogenesis in prostate cancer
-
Jain S, Chakraborty G, Raja R, Kale S, Kundu GC, (2008) Prostaglandin E2 regulates tumor angiogenesis in prostate cancer. Cancer Res 68: 7750-7759.
-
(2008)
Cancer Res
, vol.68
, pp. 7750-7759
-
-
Jain, S.1
Chakraborty, G.2
Raja, R.3
Kale, S.4
Kundu, G.C.5
-
36
-
-
38349183605
-
Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1
-
Finetti F, Solito R, Morbidelli L, Giachetti A, Ziche M, et al. (2008) Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1. J Biol Chem 283: 2139-2146.
-
(2008)
J Biol Chem
, vol.283
, pp. 2139-2146
-
-
Finetti, F.1
Solito, R.2
Morbidelli, L.3
Giachetti, A.4
Ziche, M.5
-
37
-
-
77950398950
-
15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression
-
Kundumani-Sridharan V, Niu J, Wang D, Van Quyen D, Zhang Q, et al. (2010) 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression. Blood 115: 2105-2116.
-
(2010)
Blood
, vol.115
, pp. 2105-2116
-
-
Kundumani-Sridharan, V.1
Niu, J.2
Wang, D.3
Van Quyen, D.4
Zhang, Q.5
-
38
-
-
67651114089
-
The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8
-
Cheranov SY, Wang D, Kundumani-Sridharan V, Karpurapu M, Zhang Q, et al. (2009) The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8. Blood 113: 6023-6033.
-
(2009)
Blood
, vol.113
, pp. 6023-6033
-
-
Cheranov, S.Y.1
Wang, D.2
Kundumani-Sridharan, V.3
Karpurapu, M.4
Zhang, Q.5
-
39
-
-
33745873484
-
Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells
-
Nie D, Krishnamoorthy S, Jin R, Tang K, Chen Y, et al. (2006) Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells. J Biol Chem 281: 18601-18609.
-
(2006)
J Biol Chem
, vol.281
, pp. 18601-18609
-
-
Nie, D.1
Krishnamoorthy, S.2
Jin, R.3
Tang, K.4
Chen, Y.5
-
40
-
-
1142310943
-
Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids
-
Kang JX, Wang J, Wu L, Kang ZB, (2004) Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids. Nature 427: 504.
-
(2004)
Nature
, vol.427
, pp. 504
-
-
Kang, J.X.1
Wang, J.2
Wu, L.3
Kang, Z.B.4
-
41
-
-
33747620742
-
Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids
-
Xia S, Lu Y, Wang J, He C, Hong S, et al. (2006) Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Proc Natl Acad Sci USA 103: 12499-12504.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12499-12504
-
-
Xia, S.1
Lu, Y.2
Wang, J.3
He, C.4
Hong, S.5
-
42
-
-
34848875143
-
Colitis-associated colon tumorigenesis is suppressed in transgenic mice rich in endogenous n-3 fatty acids
-
Nowak J, Weylandt KH, Habbel P, Wang J, Dignass A, et al. (2007) Colitis-associated colon tumorigenesis is suppressed in transgenic mice rich in endogenous n-3 fatty acids. Carcinogenesis 28: 1991-1995.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1991-1995
-
-
Nowak, J.1
Weylandt, K.H.2
Habbel, P.3
Wang, J.4
Dignass, A.5
-
43
-
-
45549085184
-
Reduced colitis-associated colon cancer in fat-1 (n-3 fatty acid desaturase) transgenic mice
-
Jia Q, Lupton JR, Smith R, Weeks BR, Callaway E, et al. (2008) Reduced colitis-associated colon cancer in fat-1 (n-3 fatty acid desaturase) transgenic mice. Cancer Res 68: 3985-3991.
-
(2008)
Cancer Res
, vol.68
, pp. 3985-3991
-
-
Jia, Q.1
Lupton, J.R.2
Smith, R.3
Weeks, B.R.4
Callaway, E.5
-
44
-
-
34447121230
-
Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids
-
Berquin IM, Min Y, Wu R, Wu J, Perry D, et al. (2007) Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. J Clin Invest 117: 1866-1875.
-
(2007)
J Clin Invest
, vol.117
, pp. 1866-1875
-
-
Berquin, I.M.1
Min, Y.2
Wu, R.3
Wu, J.4
Perry, D.5
-
45
-
-
79958204979
-
Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- α
-
Weylandt KH, Krause LF, Gomolka B, Chiu CY, Bilal S, et al. (2011) Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- α. Carcinogenesis 32: 897-903.
-
(2011)
Carcinogenesis
, vol.32
, pp. 897-903
-
-
Weylandt, K.H.1
Krause, L.F.2
Gomolka, B.3
Chiu, C.Y.4
Bilal, S.5
-
46
-
-
70949100689
-
Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2
-
Lim K, Han C, Dai Y, Shen M, Wu T, (2009) Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2. Mol Cancer Ther 8: 3046-3055.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3046-3055
-
-
Lim, K.1
Han, C.2
Dai, Y.3
Shen, M.4
Wu, T.5
-
47
-
-
55749110745
-
Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation
-
Lu Y, Nie D, Witt WT, Chen Q, Shen M, et al. (2008) Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation. Mol Cancer Ther 7: 3203-3211.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3203-3211
-
-
Lu, Y.1
Nie, D.2
Witt, W.T.3
Chen, Q.4
Shen, M.5
-
48
-
-
77955513412
-
The non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model
-
Griffitts J, Saunders D, Tesiram YA, Reid GE, Salih A, et al. (2010) The non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model. Biochim Biophys Acta 1801: 1133-1144.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 1133-1144
-
-
Griffitts, J.1
Saunders, D.2
Tesiram, Y.A.3
Reid, G.E.4
Salih, A.5
|