메뉴 건너뛰기




Volumn 9, Issue 11, 2012, Pages

Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog

Author keywords

Arrhythmias; Calcineurin; CaMKII; Chronic AV block dog; Ventricular remodeling

Indexed keywords

CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLOSPORIN A; DOFETILIDE; HISTONE DEACETYLASE 4; MESSENGER RNA; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PHOSPHOLAMBAN; PROTEIN KINASE B;

EID: 84867870977     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2012.07.023     Document Type: Article
Times cited : (13)

References (48)
  • 3
    • 0033054549 scopus 로고    scopus 로고
    • Calcineurin and human heart failure
    • H.W. Lim, J.D. Molkentin Calcineurin and human heart failure Nat Med 5 1999 246 247
    • (1999) Nat Med , vol.5 , pp. 246-247
    • Lim, H.W.1    Molkentin, J.D.2
  • 4
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • J.D. Molkentin, J.R. Lu, C.L. Antos A calcineurin-dependent transcriptional pathway for cardiac hypertrophy Cell 93 1998 215 228
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3
  • 5
    • 0037015257 scopus 로고    scopus 로고
    • Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy
    • Y. Wu, J. Temple, R. Zhang Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy Circulation 106 2002 1288 1293
    • (2002) Circulation , vol.106 , pp. 1288-1293
    • Wu, Y.1    Temple, J.2    Zhang, R.3
  • 7
    • 52049114958 scopus 로고    scopus 로고
    • NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure
    • M. Bourajjaj, A.S. Armand, P.A. da Costa Martins NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure J Biol Chem 283 2008 22295 22303
    • (2008) J Biol Chem , vol.283 , pp. 22295-22303
    • Bourajjaj, M.1    Armand, A.S.2    Da Costa Martins, P.A.3
  • 8
    • 66449097490 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
    • 2+/calmodulin- dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice J Clin Invest 119 2009 1230 1240
    • (2009) J Clin Invest , vol.119 , pp. 1230-1240
    • Ling, H.1    Zhang, T.2    Pereira, L.3
  • 9
    • 0032239112 scopus 로고    scopus 로고
    • ++/calmodulin- dependent protein kinase, decreases early afterdepolarizations in rabbit heart
    • ++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart J Pharmacol Exp Ther 287 1998 996 1006
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 996-1006
    • Anderson, M.E.1    Braun, A.P.2    Wu, Y.3
  • 10
    • 70349471243 scopus 로고    scopus 로고
    • Ca/calmodulin kinase II differentially modulates potassium currents
    • S. Wagner, E. Hacker, E. Grandi Ca/calmodulin kinase II differentially modulates potassium currents Circ Arrhythm Electrophysiol 2 2009 285 294
    • (2009) Circ Arrhythm Electrophysiol , vol.2 , pp. 285-294
    • Wagner, S.1    Hacker, E.2    Grandi, E.3
  • 12
    • 0032764067 scopus 로고    scopus 로고
    • Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits
    • A. Mazur, D.M. Roden, M.E. Anderson Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits Circulation 100 1999 2437 2442
    • (1999) Circulation , vol.100 , pp. 2437-2442
    • Mazur, A.1    Roden, D.M.2    Anderson, M.E.3
  • 13
    • 6444237997 scopus 로고    scopus 로고
    • Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs
    • M.B. Thomsen, S.C. Verduyn, M. Stengl Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs Circulation 110 2004 2453 2459
    • (2004) Circulation , vol.110 , pp. 2453-2459
    • Thomsen, M.B.1    Verduyn, S.C.2    Stengl, M.3
  • 14
    • 83755172797 scopus 로고    scopus 로고
    • Comparison of I(Kr) blocking drugs moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals insufficient specificity of isolated cardiomyocytes
    • L. Nalos, R. Varkevisser, M. Jonsson Comparison of I(Kr) blocking drugs moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals insufficient specificity of isolated cardiomyocytes Br J Pharmacol 165 2012 467 478
    • (2012) Br J Pharmacol , vol.165 , pp. 467-478
    • Nalos, L.1    Varkevisser, R.2    Jonsson, M.3
  • 15
    • 33745812011 scopus 로고    scopus 로고
    • CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy
    • J. Backs, K. Song, S. Bezprozvannaya, S. Chang, E.N. Olson CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy J Clin Invest 116 2006 1853 1864
    • (2006) J Clin Invest , vol.116 , pp. 1853-1864
    • Backs, J.1    Song, K.2    Bezprozvannaya, S.3    Chang, S.4    Olson, E.N.5
  • 16
    • 60549085044 scopus 로고    scopus 로고
    • The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
    • J. Backs, T. Backs, S. Neef The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload Proc Natl Acad Sci U S A 106 2009 2342 2347
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2342-2347
    • Backs, J.1    Backs, T.2    Neef, S.3
  • 17
    • 36849036738 scopus 로고    scopus 로고
    • CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses
    • 3507835087
    • T. Zhang, M. Kohlhaas, J. Backs CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses J Biol Chem 282 2007 3507835087
    • (2007) J Biol Chem , vol.282
    • Zhang, T.1    Kohlhaas, M.2    Backs, J.3
  • 18
    • 33646449520 scopus 로고    scopus 로고
    • Akt1 is required for physiological cardiac growth
    • B. DeBosch, I. Treskov, T.S. Lupu Akt1 is required for physiological cardiac growth Circulation 113 2006 2097 2104
    • (2006) Circulation , vol.113 , pp. 2097-2104
    • Debosch, B.1    Treskov, I.2    Lupu, T.S.3
  • 19
    • 0032530525 scopus 로고    scopus 로고
    • Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling
    • M.A. Vos, S.H. de Groot, S.C. Verduyn Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling Circulation 98 1998 1125 1135
    • (1998) Circulation , vol.98 , pp. 1125-1135
    • Vos, M.A.1    De Groot, S.H.2    Verduyn, S.C.3
  • 20
    • 0034711161 scopus 로고    scopus 로고
    • Contractile adaptations preserving cardiac output predispose the hypertrophied canine heart to delayed afterdepolarization-dependent ventricular arrhythmias
    • S.H. de Groot, M. Schoenmakers, M.M. Molenschot, J.D. Leunissen, H.J. Wellens, M.A. Vos Contractile adaptations preserving cardiac output predispose the hypertrophied canine heart to delayed afterdepolarization-dependent ventricular arrhythmias Circulation 102 2000 2145 2151
    • (2000) Circulation , vol.102 , pp. 2145-2151
    • De Groot, S.H.1    Schoenmakers, M.2    Molenschot, M.M.3    Leunissen, J.D.4    Wellens, H.J.5    Vos, M.A.6
  • 21
    • 70349236112 scopus 로고    scopus 로고
    • CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes
    • S.M. MacDonnell, J. Weisser-Thomas, H. Kubo CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes Circ Res 105 2009 316 325
    • (2009) Circ Res , vol.105 , pp. 316-325
    • MacDonnell, S.M.1    Weisser-Thomas, J.2    Kubo, H.3
  • 22
    • 54449101791 scopus 로고    scopus 로고
    • Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes
    • L. Xiao, P. Coutu, L.R. Villeneuve Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes Circ Res 103 2008 733 742
    • (2008) Circ Res , vol.103 , pp. 733-742
    • Xiao, L.1    Coutu, P.2    Villeneuve, L.R.3
  • 23
    • 33749014131 scopus 로고    scopus 로고
    • Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy
    • M.S. Khoo, J. Li, M.V. Singh Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy Circulation 114 2006 1352 1359
    • (2006) Circulation , vol.114 , pp. 1352-1359
    • Khoo, M.S.1    Li, J.2    Singh, M.V.3
  • 24
    • 9344261464 scopus 로고    scopus 로고
    • Biventricular hypertrophy in dogs with chronic AV block: Effects of cyclosporin A on morphology and electrophysiology
    • K.D. Schreiner, K. Kelemen, J. Zehelein Biventricular hypertrophy in dogs with chronic AV block: effects of cyclosporin A on morphology and electrophysiology Am J Physiol Heart Circ Physiol 287 2004 H2891 H2898
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Schreiner, K.D.1    Kelemen, K.2    Zehelein, J.3
  • 25
    • 50049111108 scopus 로고    scopus 로고
    • The canine model with chronic, complete atrio-ventricular block
    • A. Oros, J.D. Beekman, M.A. Vos The canine model with chronic, complete atrio-ventricular block Pharmacol Ther 119 2008 168 178
    • (2008) Pharmacol Ther , vol.119 , pp. 168-178
    • Oros, A.1    Beekman, J.D.2    Vos, M.A.3
  • 26
    • 61949111681 scopus 로고    scopus 로고
    • The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice
    • C.S. Chiang, C.H. Huang, H. Chieng The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice Circ Res 104 2009 522 530
    • (2009) Circ Res , vol.104 , pp. 522-530
    • Chiang, C.S.1    Huang, C.H.2    Chieng, H.3
  • 27
    • 33846957120 scopus 로고    scopus 로고
    • 2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block
    • 2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block J Physiol 579 Pt 1 2007 147 160
    • (2007) J Physiol , vol.579 , Issue.PART 1 , pp. 147-160
    • Antoons, G.1    Volders, P.G.2    Stankovicova, T.3
  • 29
    • 73349084993 scopus 로고    scopus 로고
    • 2+-calmodulin protein kinase II and promotes a death pathway conserved across different species
    • 2+-calmodulin protein kinase II and promotes a death pathway conserved across different species Circ Res 105 2009 1204 1212
    • (2009) Circ Res , vol.105 , pp. 1204-1212
    • Palomeque, J.1    Rueda, O.V.2    Sapia, L.3
  • 30
    • 75749089243 scopus 로고    scopus 로고
    • Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion
    • W. Zhang, D.Q. Chen, F. Qi, J. Wang, W.Y. Xiao, W.Z. Zhu Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion J Cardiovasc Pharmacol 55 2010 96 105
    • (2010) J Cardiovasc Pharmacol , vol.55 , pp. 96-105
    • Zhang, W.1    Chen, D.Q.2    Qi, F.3    Wang, J.4    Xiao, W.Y.5    Zhu, W.Z.6
  • 31
    • 0034711160 scopus 로고    scopus 로고
    • Enhanced Ca(2+) release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: Potential link between contractile adaptation and arrhythmogenesis
    • K.R. Sipido, P.G. Volders, S.H. de Groot Enhanced Ca(2+) release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis Circulation 102 2000 2137 2144
    • (2000) Circulation , vol.102 , pp. 2137-2144
    • Sipido, K.R.1    Volders, P.G.2    De Groot, S.H.3
  • 32
    • 0032530552 scopus 로고    scopus 로고
    • Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes
    • P.G. Volders, K.R. Sipido, M.A. Vos, A. Kulcsar, S.C. Verduyn, H.J. Wellens Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes Circulation 98 1998 1136 1147
    • (1998) Circulation , vol.98 , pp. 1136-1147
    • Volders, P.G.1    Sipido, K.R.2    Vos, M.A.3    Kulcsar, A.4    Verduyn, S.C.5    Wellens, H.J.6
  • 33
    • 84856100794 scopus 로고    scopus 로고
    • Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
    • B.J. He, M.L. Joiner, M.V. Singh Oxidation of CaMKII determines the cardiotoxic effects of aldosterone Nat Med 17 2011 1610 1618
    • (2011) Nat Med , vol.17 , pp. 1610-1618
    • He, B.J.1    Joiner, M.L.2    Singh, M.V.3
  • 34
    • 42949085382 scopus 로고    scopus 로고
    • A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
    • J.R. Erickson, M.L. Joiner, X. Guan A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation Cell 133 2008 462 474
    • (2008) Cell , vol.133 , pp. 462-474
    • Erickson, J.R.1    Joiner, M.L.2    Guan, X.3
  • 35
    • 0037044405 scopus 로고    scopus 로고
    • Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block
    • Y. Tsuji, T. Opthof, K. Yasui Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block Circulation 106 2002 2012 2018
    • (2002) Circulation , vol.106 , pp. 2012-2018
    • Tsuji, Y.1    Opthof, T.2    Yasui, K.3
  • 36
    • 79958084460 scopus 로고    scopus 로고
    • Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm
    • Y. Tsuji, M. Hojo, N. Voigt Ca(2+)-related signaling and protein phosphorylation abnormalities play central roles in a new experimental model of electrical storm Circulation 123 2011 2192 2203
    • (2011) Circulation , vol.123 , pp. 2192-2203
    • Tsuji, Y.1    Hojo, M.2    Voigt, N.3
  • 37
    • 80054015760 scopus 로고    scopus 로고
    • Drug-induced torsade de pointes arrhythmias in the chronic av block dog are perpetuated by focal activity
    • M. Boulaksil, J.G. Jungschleger, G. Antoons Drug-induced torsade de pointes arrhythmias in the chronic av block dog are perpetuated by focal activity Circ Arrhythm Electrophysiol 4 2011 566 576
    • (2011) Circ Arrhythm Electrophysiol , vol.4 , pp. 566-576
    • Boulaksil, M.1    Jungschleger, J.G.2    Antoons, G.3
  • 38
    • 76449092876 scopus 로고    scopus 로고
    • Late Na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model
    • G. Antoons, A. Oros, J.D. Beekman Late Na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model J Am Coll Cardiol 55 2010 801 809
    • (2010) J Am Coll Cardiol , vol.55 , pp. 801-809
    • Antoons, G.1    Oros, A.2    Beekman, J.D.3
  • 39
    • 70349446744 scopus 로고    scopus 로고
    • The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome
    • X. Qi, Y.H. Yeh, D. Chartier The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome Circ Arrhythm Electrophysiol 2 2009 295 304
    • (2009) Circ Arrhythm Electrophysiol , vol.2 , pp. 295-304
    • Qi, X.1    Yeh, Y.H.2    Chartier, D.3
  • 40
    • 70349446744 scopus 로고    scopus 로고
    • The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome
    • X. Qi, Y.H. Yeh, D. Chartier The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome Circ Arrhythm Electrophysiol 2 2009 295 304
    • (2009) Circ Arrhythm Electrophysiol , vol.2 , pp. 295-304
    • Qi, X.1    Yeh, Y.H.2    Chartier, D.3
  • 41
    • 33744541775 scopus 로고    scopus 로고
    • CaMKII-independent effects of KN93 and its inactive analog KN92: Reversible inhibition of L-type calcium channels
    • L. Gao, L.A. Blair, J. Marshall CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels Biochem Biophys Res Commun 345 2006 1606 1610
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1606-1610
    • Gao, L.1    Blair, L.A.2    Marshall, J.3
  • 42
    • 52049114958 scopus 로고    scopus 로고
    • NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure
    • M. Bourajjaj, A.S. Armand, P.A. da Costa Martins NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure J Biol Chem 283 2008 22295 22303
    • (2008) J Biol Chem , vol.283 , pp. 22295-22303
    • Bourajjaj, M.1    Armand, A.S.2    Da Costa Martins, P.A.3
  • 43
    • 83755172797 scopus 로고    scopus 로고
    • Comparison of I(Kr) blocking drugs moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals insufficient specificity of isolated cardiomyocytes
    • Comparison of I(Kr) blocking drugs moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals insufficient specificity of isolated cardiomyocytes Br J Pharmacol 165 2012 467 478
    • (2012) Br J Pharmacol , vol.165 , pp. 467-478
  • 44
    • 76449092876 scopus 로고    scopus 로고
    • Late Na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model
    • G. Antoons, A. Oros, J.D. Beekman Late Na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model J Am Coll Cardiol 55 2010 801 809
    • (2010) J Am Coll Cardiol , vol.55 , pp. 801-809
    • Antoons, G.1    Oros, A.2    Beekman, J.D.3
  • 45
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • T. Taigen, L.J. De Windt, H.W. Lim, J.D. Molkentin Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy Proc Natl Acad Sci U S A 97 2000 1196 1201
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkentin, J.D.4
  • 46
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • J.D. Molkentin, J.R. Lu, C.L. Antos A calcineurin-dependent transcriptional pathway for cardiac hypertrophy Cell 93 1998 215 228
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3
  • 47
    • 0032239112 scopus 로고    scopus 로고
    • ++/calmodulin- dependent protein kinase, decreases early afterdepolarizations in rabbit heart
    • ++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart J Pharmacol Exp Ther 287 1998 996 1006
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 996-1006
    • Anderson, M.E.1    Braun, A.P.2    Wu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.