Identification and expression of δ-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium

Circulation Research

Volumn 84, Issue 6, 1999, Pages 713-721

  Hoch, Brigitte ^a   Meyer, Rudolf ^b   Hetzer, Roland ^b   Krause, Ernst Georg ^a   Karczewski, Peter ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b DEUTSCHES HERZZENTRUM BERLIN   (Germany)

Author keywords

Ca2+ calmodulin dependent protein kinase II; Dilated cardiomyopathy; Human cardiac and skeletal muscle; CaMKII

Indexed keywords

ATRIAL NATRIURETIC FACTOR; COMPLEMENTARY DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; ISOENZYME; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN SUBUNIT;

ADULT; ARTICLE; CLINICAL ARTICLE; GENE SEQUENCE; HEART DILATATION; HEART MUSCLE; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OPTICAL DENSITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SKELETAL MUSCLE;

EID: 0033515617     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.84.6.713     Document Type: Article

References (40)

1. Braun AP, Schulman H. The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annu Rev Physiol. 1995; 57:417-445.
2. 2+/calmodulin kinase. Nature. 1994;371: 347-350.
3. 2. EMBO J. 1992;11:507-517.
4. 2+/calmodulin-dependent protein kinases propagate signals from endothelin-1 receptors to the c-fos promoter. Mol Cell Biol. 1996;16:5915-5923.
5. 2+/calmodulin dependent protein kinase II in PC12 cells alters cell growth, morphology, and nerve growth factor induced differentiation. J Neurosci. 1997;17:924-931.
6. Tobimatsu T, Fujisawa H. Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs. J Biol Chem. 1989;264: 17907-17912.
7. 2+/calmodulin-dependent protein kinase isoforms in rat brain. J Neurosci. 1995;15:6797-6808.
8. 2+/calmodulin-dependent protein kinase II. J Biol Chem. 1993;268:14443-14449.
9. Mayer P, Möhlig M, Idlibe D, Pfeiffer A. Novel and uncommon isoforms of the calcium sensing enzyme calcium/calmodulin dependent protein kinase II in heart tissue. Basic Res Cardiol. 1995;90:372-379.
10. 2+/calmodulin-dependent protein kinase II revealed by electron microscopy. J Cell Biol. 1991;115:1049-1060.
11. Srinivasan M, Edman CF, Schulman, H. Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus. J Cell Biol. 1994;126:839-852.
12. 2+/calmodulin-dependent protein kinase II blocks its nuclear targeting. J Biol Chem. 1998;273:19763-19771.
13. 2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. J Biol Chem. 1997;272: 31203-31208.
14. 2+ current in rabbit ventricular myocytes. Circ Res. 1994;75:854-861.
15. Hohenegger M, Suko J. Phosphorylation of the purified cardiac ryanodine receptor by exogenous and endogenous protein kinases. Biochem J. 1993; 296:303-308.
16. 2+/ calmodulin-dependent protein kinase. J Biol Chem. 1994;269: 31198-31206.
17. Simmerman HKB, Collins JH, Theibert JL, Wegener AD, Jones LR. Sequence analysis of phospholamban: identification of phosphorylation sites and two major structural domains. J Biol Chem. 1986;261: 13333-13341.
18. 2+/calmodulin-dependent protein kinase II γ-subunit variants expressed in vascular smooth muscle, brain, and cardiomyocytes. J Biol Chem. 1997;272: 9393-9400.
19. Baltas LG, Karczewski P, Krause EG. The cardiac sarcoplasmic reticulum phospholamban kinase is a distinct δ-CaM kinase isozyme. FEBS Lett. 1995;373:71-75.
20. Hoch B, Haase H, Schulze W, Hagemann D, Morano I, Krause E-G, Karczewski P. Differentiation-dependent expression of cardiac δ-CaMKII isoforms. J Cell Biochem. 1998;68:259-268.
21. 2+/ calmodulin-dependent protein kinase isoforms. Biochim Biophys Acta. 1994;1221:89-101.
22. Tombes RM, Krystal GW. Identification of novel human tumor cell-specific CaMK-II variants. Biochim Biophys Acta. 1997;1355:281-292.
23. Morgan JP. Abnormal intracellular modulation of calcium as a major cause of cardiac contractile dysfunction. N Engl J Med. 1991;325: 625-632.
24. Beuckelmann DJ, Näbauer M, Erdmann E. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation. 1992;85:1046-1055.
25. de Tombe PP. Altered contractile function in heart failure. Cardiovasc Res. 1998;37:367-380.
26. 2+-ATPase gene. Circ Res. 1992; 71:9-17.
27. Arai M, Alpert NR, MacLennan DH, Barton P, Periasamy M. Alterations in sarcoplasmic reticulum gene expression in human heart failure: a possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. Circ Res. 1993;72:463-469.
28. Kunkel B, Lapp H, Kober G, Kaltenbach M. Light-microscopic evaluation of myocardial biopsy. In: Kaltenbach M, Loogen F, Olsen EGJ eds. Cardiomyopathy and Myocardial Biopsy. Berlin/Heidelberg/New York: Springer-Verlag; 1978;62-70.
29. Kingston RE, Chomczynski P, Sacchi N. Guanidinium methods for total RNA preparation. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Struhl K, eds. Current Protocols in Molecular Biology. New York NY: John Wiley & Sons; 1994;I:4.2.1-4.2.9.
30. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
31. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and applications. Proc Natl Acad Sci USA. 1979;76:4350-4354.
32. Goldman JH, McKenna WJ. Immunopathogenesis of dilated cardiomyopathies. Curr Opin Cardiol 1995;10:306-311.
33. Anderson PA, Greig A, Mark TM, Malouf NN, Oakeley AE, Ungerleider RM, Allen PD, Kay BK. Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart. Circ Res. 1995;76:681-686.
34. Arai M, Matsui H, Periasamy M. Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure. Circ Res. 1994;74:555-564.
35. Franch HA, Dixon RAF, Blaine EH, Siegl PKS. Ventricular atrial natriuretic factor in the cardiomyopathic hamster model of congestive heart failure. Circ Res. 1988;62:31-36.
36. Movsesian MA, Schwinger RHG. Calcium sequestration by the sarcoplasmic reticulum in heart failure. Cardiovasc Res. 1998;37:352-359.
37. 2+-ATPase in failing and nonfailing human myocardium. Circ Res. 1994;75:434-442.
38. Meyer M, Schillinger W, Pieske B, Holubarsch C, Heilmann C, Posival H, Kuwajima G, Mikoshiba K, Just H, Hasenfuss G. Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy. Circulation. 1995;92:778-784.
39. 2+- and cyclic AMP/phorbol 12-myristate 13-acetate-responsive elements. J Neurochem. 1996;66:1802-1809.
40. Yoshida K, Imaki J, Matsuda H, Hagiwara M. Light-induced CREB phosphorylation and gene expression in rat retinal cells. J Neurochem. 1995;65:1499-1504.