Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion

Journal of Cardiovascular Pharmacology

Volumn 55, Issue 1, 2010, Pages 96-105

  Zhang, Wei ^a,b   Chen, Dong Qin ^a,b   Qi, Feng ^a   Wang, Jing ^a   Xiao, Wen Yan ^a   Zhu, Wei Zhong ^a  

^a NANTONG UNIVERSITY   (China)

^b First Hospital of Jiaxing   (China)

Author keywords

Angiotensin II; CaMKII; Cardiac fibrosis; Electrical field stimulation; Extracellular matrix; Fibroblast

Indexed keywords

ANGIOTENSIN II; AUTOCAMTIDE 2 RELATED INHIBITORY PEPTIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MESSENGER RNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PHOSPHOTRANSFERASE INHIBITOR; RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ELECTRIC FIELD; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEART MUSCLE FIBROSIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; UPREGULATION;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL PROLIFERATION; ELECTRIC STIMULATION; EXTRACELLULAR MATRIX; FIBROBLASTS; HEART VENTRICLES; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES;

EID: 75749089243     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181c9548b     Document Type: Article

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