Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling

Circulation

Volumn 98, Issue 11, 1998, Pages 1125-1135

  Vos, M A ^a   De Groot, S H M ^b   Verduyn, S C ^b   Van Der Zande, J ^b   Leunissen, H D M ^b   Cleutjens, J P M ^b   Van Bilsen, M ^b   Daemen, M J A P ^b   Schreuder, J J ^b   Allessie, M A ^b   Wellens, H J J ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b NONE

Author keywords

Action potentials; Cardiac function; Early after dipolarizations; Electrophysiology; Fibrosis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR BLOCK; COMORBIDITY; DISEASE ASSOCIATION; DOG; HEART DEPOLARIZATION; HEART MUSCLE POTENTIAL; HEART PACING; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; SINUS RHYTHM; TORSADE DES POINTES;

EID: 0032530525     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.98.11.1125     Document Type: Article

References (50)

1. Gorgels APM, Beekman HDM, Brugada P, Dassen WRM, Richards DAB, Wellens HJJ. Extrastimulus related shortening of the first post-pacing interval in digitalis induced ventricular tachycardia. J Am Coll Cardiol. 1984;1:840-857.
2. Vos MA, Gorgels APM, Leunissen HDM, Wellens HJJ. Flunarizine allows differentiation between mechanisms of arrhythmias in the intact heart. Circulation. 1990;81:343-349.
3. Vos MA, Verduyn SC, Gorgels APM, Lipscei GC, Wellens HJJ. Reproducible induction of early afterdepolarizations and torsade de pointes arrhythmias by d-sotalol and pacing in the dog with chronic atrioventricular block. Circulation. 1995;91:864-872.
4. Verduyn SC, Vos MA, van der Zande J, van der Hulst FF, Wellens HJJ. Role of interventricular dispersion of repolarization in acquired torsade de pointes arrhythmias: reversal by magnesium. Cardiovasc Res. 1997;34: 453-463.
5. Verduyn SC, Vos MA, van der Zande J, Kulcsar A, Wellens HJJ. Further observations to elucidate the role of interventricular dispersion of repolarization and early afterdepolarizations in the genesis of acquired torsade de pointes arrhythmias: a comparison between almokalant and d-sotalol using the dog as its own control. J Am Coll Cardiol. 1997;30:1575-1584.
6. Turina M, Bussmann WD, Krayenbuhl HP. Contractility of the hypertrophied canine heart in chronic volume overload. Cardiovasc Res. 1969; 3:486-495.
7. Wusten B, Flameng W, Winkler B, Schaper W. Role of cardiac contractility in hypertrophy from chronic volume loading. Cardiovasc Res. 1977;11:132-140.
8. Newman WH. Contractile status of hypertrophied LV in long standing volume overload. Am J Physiol. 1978;234:H88-H93.
9. Kannel WB, Sorlie P. Left ventricular hypertrophy in hypertension: prognostic and pathogenetic implications: the Framingham study. In: Strauer R, ed. The Heart in Hypertension. Berlin, Germany: Springer Verlag; 1981:223-242.
10. Ghali JK, Kadakia SK, Cooper RS, Liao Y. Impact of left ventricular arrhythmias in the absence of coronary artery disease. J Am Coll Cardiol. 1991;17:1277-1282.
11. Haverkamp W, Martinez-Rubio A, Hief C, Lammers A, Mühlenkamp S, Wichter T, Breithardt G, Borggrefe M. Efficacy and safety of dl-sotalol in patients with ventricular tachycardia and in survivors of cardiac arrest. J Am Coll Cardiol. 1997;30:487-495.
12. Kaab S, Bradley Nuss HB, Chiamvimonvat N, O'Rourke B, Pak PH, Kass DA, Marban E, Tomaselli GF. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing induced heart failure. Circ Res. 1996;78:262-273.
13. Sabbah HN, Goldberg AD, Schoels W, Kono T, Webb C, Brachmann J, Goldstein S. Spontaneous and inducible ventricular arrhythmias in a canine model of chronic heart failure: relation to haemodynamics and sympathoadrenergic activation. Eur Heart J. 1992;13:1562-1572.
14. Ben-David J, Zipes DP, Ayers GM, Pride HP. Canine left ventricular hypertrophy predisposes to ventricular tachycardia induction by phase 2 early afterdepolarizations after administration of Bay K 8644. J Am Coll Cardiol. 1992;20:1576-1584.
15. Cameron JS, Myerburg RJ, Wong SS, Gaide MS, Epstein K, Alvarez TR, Gelband H, Guse PA, Bassett AL. Electrophysiologic consequences of chronic experimentally induced left ventricular pressure overload. J Am Coll Cardiol. 1983;2:481-487.
16. Tomaselli GF, Beuckelmann DJ, Calkins HG, Berger RD, Kessler PD, Lawrence JH, Kass D, Feldman AM, Marban E. Sudden cardiac death in heart failure: the role of abnormal repolarization. Circulation. 1994;90: 2534-2539.
17. Aronson RS, Ming Z. Cellular mechanisms of arrhythmias in hypertrophied and failing myocardium. Circulation. 1993;87(suppl VII):VII-76-VII-83.
18. Volders PGA, Sipido KR, Vos MA, Kulscar A, Verduyn SC, Wellens HJJ. Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete AV block and acquired torsade de pointes. Circulation. 1998;98:1136-1147.
19. Vatner DE, Sato N, Kiuchi K, Shannon RP, Vatner SF. Decrease in myocardial ryanodine receptors and altered excitation-contraction coupling early in the development of heart failure. Circulation. 1994;90: 1423-1430.
20. Schreuder JJ, van der Veen FH, van der Velde ET, Delahaye F, Alfieri O, Jegaden O, Lorusso R, Jansen JRC, van Ommen V, Finet G, Wellens HJJ. Beat-to-beat analysis of left ventricular pressure-volume relation and stroke volume by conductance catheter and aortic Modelflow in cardiomyoplasty patients. Circulation. 1995;91:2010-2017.
21. Nussberger J, Brunner DB, Waeber B, Brunner HR. True versus immunoreactive angiotensin II in human plasma. Hypertension. 1985;7(suppl I):I-1-I-7.
22. Rosmalen FM, Tan AC, Tan HS, Benraad TJ. A sensitive radioimmunoassay of atrial natriuretic peptide in human plasma, using a tracer with an immobilized glycouril agent. Clin Chem. 1987;165:331-340.
23. Kubasik NP, Warren K, Sine HE. Evaluation of a new commercial radioassay kit for aldosterol using an iodinated tracer. Clin Biochem. 1987;12:59-61.
24. Van der Hoorn K, Boomsma F, Man in 't Veld AJ, Schalekamp MADH. Determination of catecholamines in human plasma by high-performance liquid chromatography: comparison between a new method with fluorescence detection and an established method with electrochemical detection. J Chromatogr. 1989;487:17-28.
25. Weber KT, Pick R, Silver MA, Moe GW, Janicki JS, Zucker IH, Armstrong PW. Fibrillar collagen and remodeling of dilated canine LV. Circulation. 1990;82:1387-1401.
26. Sabbah HN, Sharov VG, Lesch M, Goldstein S. Progression of heart failure: a role for interstitial fibrosis. Mol Cell Biochem. 1995;147:29-34.
27. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: A Laboratory Manual 2nd ed. Cold Spring Habor, NY: Cold Spring Harbor Laboratory Press; 1989.
28. Holmer SR, Riegger AJG, Notheis WF, Kromer EP, Kochsiek K. Hemodynamic changes and renal plasma in early heart failure: implications for renin, aldosterone, norepinephrine, atrial natriuretic peptide and prostacyclin. Basic Res Cardiol. 1987;82:101-108.
29. Moe GW, Stopps TP, Angus C, Forster C, de Bold A, Armstrong PW. Alterations in serum sodium in relation to atrial natriuretic factor and other neuroendocrine variables in experimental pacing-induced heart failure. J Am Coll Cardiol. 1989;13:173-179.
30. Spinale FG, Holzgrefe HH, Mukherjee R, Arthur SR, Child MJ, Powell JR, Koster WH. Left ventricular and myocyte structure and function after early recovery from tachycardia induced cardiomyopathy. Am J Physiol. 1995;268:H836-H847.
31. Perreault CL, Shannon RP, Komamura K, Vatner SF, Morgan JP. Abnormalities in intracellular calcium regulation and contractile function in myocardium from dogs with pacing induced heart failure. J Clin Invest. 1992;89:932-938.
32. Williams RE, Kass DA, Kawagoe Y, Pak P, Tunin RS, Shah R, Hwang A, Feldman AM. Endomyocardial gene expression during development of pacing tachycardia-induced heart failure in the dog. Circ Res. 1994; 75:615-623.
33. McDonald KM, Francis GS, Carlyle PF, Hauer K, Matthews J, Hunter DW, Conn JN. Hemodynamic, left ventricular structural and hormonal changes after discrete myocardial damage in the dog. J Am Coll Cardiol. 1992;19:460-467.
34. Hittinger L, Patrick T, Ihara T, Hasebe N, Shen YT, Kalthof B, Shannon RP, Vatner SF. Exercise induced cardiac dysfunction in both moderated, compensated, and severe hypertrophy. Circulation. 1994; 89:2219-2231.
35. Hasebe N, Hittinger L, Kohin S, Shen YT, Graham RM, Vatner SF. Effects of hypertrophy on left atrial and ventricular compliance and plasma ANF levels in conscious dogs. Am J Physiol. 1995;268:H781-H787.
36. Omens JH, Covell JW. Transmural distribution of myocardial tissue growth induced by volume overload hypertrophy in the dog. Circulation. 1991;84:1235-1245.
37. Urabe Y, Hamada Y, Spinale FG, Carabello BA, Kent RL, Cooper GIV, Mann DL. Cardiocyte contractile performance in experimental biventricular volume-overload hypertrophy. Am J Physiol. 1993;264: H1615-H1623.
38. Starzl TE, Gaertner RA. Chronic heart block in dogs: a method for producing experimental heart failure. Circulation. 1955;12:259-270.
39. Brockman SK. Cardiodynamics of complete heart block. Am J Cardiol. 1965;16:72-83.
40. Franz MR, Burkhoff D, Yue DT, Sagawa K. Mechanically induced action potential changes and arrhythmia in isolated and in situ canine hearts. Cardiovasc Res. 1989;23:213-223.
41. Antzelevitch C, Sicouri S. Clinical relevance of cardiac arrhythmias generated by afterdepolarizations: role of M cells in the generation of U waves, triggered activity and torsade de pointes. J Am Coll Cardiol. 1994;23:259-277.
42. Shimizu W, Antzelevitch C. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation. 1997;96:2038-2047.
43. Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H. Electrophysiological characteristics of cells spanning the left ventricular wall of human heart: evidence for the presence of M cells. J Am Coll Cardiol. 1995;26:185-192.
44. El-Sherif N, Caref EB, Yin H, Restivo M. The electrophysiological mechanism of ventricular arrhythmias in the long-QT syndrome: tridimensional mapping of activation and recovery patterns. Circ Res. 1996;79:474-492.
45. Rials SJ, Wu Y, Ford N, Pauletto FJ, Abramson SV, Rubin AM, Marinchak RA, Kowey PR. Effect of left ventricular hypertrophy and its regression on electrophysiology and vulnerability to inducible arrhythmia in the feline heart. Circulation. 1995;91:426-430.
46. Kreher P, Ristori MT, Verdetti J. Effects of chronic angiotensin I-converting enzyme inhibition on the relations between ventricular action potential changes and myocardial hypertrophy in aging hearts. J Cardiovasc Pharmacol. 1995;25:75-80.
47. Derakhchan K, Klug D, Bouchard C, Helie F, Pharand C, Sasyniuk B, Kus T, Cardinal R. Torsade de pointes induced by d-sotalol in canine AV-block: initiation in the conduction system followed by spatially unstable reentry. Circulation. 1995;92(suppl I):I-640. Abstract.
48. Weissenburger J, Nesterenko VV, Antzelevitch C. M cells contribute to transmural dispersion of repolarization and to the development of torsade de pointes in the canine heart in vivo. Pacing Clin Electrophysiol. 1996; 19:707. Abstract.
49. Kurita T, Ohe T, Marui N, Aihara N, Takaki H, Kamakura S, Matsuhisa M, Shimomura K. Bradycardia induced abnormal QT-prolongation in patients with complete AV block with torsade de pointes. Am J Cardiol. 1992;69:628-633.
50. Gladman G, Davies AM, Fogelman R, Hamilton RW, Gow RM. Torsade de pointes, acquired complete heart block and inappropriately long QT in childhood. Can J Cardiol. 1996;12:683-685.