Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 11, 2012, Pages 1127-1139

  More, Amar S ^a   Kumari, Rashmi R ^a   Gupta, Gaurav ^a   Kathirvel, Kandasamy ^a   Lonare, Milindmitra K ^a   Dhayagude, Rohini S ^a   Kumar, Dhirendra ^a   Kumar, Dinesh ^a   Sharma, Anil K ^a   Tandan, Surendra K ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Acetaminophen; Inducible nitric oxide synthase (iNOS); Peroxynitrite; Reactive oxygen species; S methylisothiourea

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; INDUCIBLE NITRIC OXIDE SYNTHASE; METHYLISOTHIOUREA; NITRATE; NITRITE; PARACETAMOL; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HYPOTENSION; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; RAT;

ACETAMINOPHEN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; ISOTHIURONIUM; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 84867842188     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0789-0     Document Type: Article

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