Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat

Life Sciences

Volumn 74, Issue 6, 2003, Pages 793-802

  Kamanaka, Yoshihisa ^a   Kawabata, Atsufumi ^b   Matsuya, Hidekazu ^a   Taga, Chiyomi ^a   Sekiguchi, Fumiko ^b   Kawao, Naoyuki ^b  

^a ONO PHARMACEUTICAL CO   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

Acetaminophen; Hepatotoxicity; Inducible nitric oxide synthase (iNOS)

Indexed keywords

7 CHLORO 3 IMINO 5 METHYL 2 AZABICYCLO[4.1.0]HEPTANE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PARACETAMOL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; LIVER INJURY; LIVER TOXICITY; MALE; NONHUMAN; RAT;

EID: 0345118244     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.09.036     Document Type: Article

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