Protein carbonyl measurements show evidence of early oxidative stress in critically ill patients

Critical Care Medicine

Volumn 28, Issue 1, 2000, Pages 143-149

  Winterbourn, Christine C ^a   Buss, I Hendrikje ^a   Chan, Timothy P ^a   Plank, Lindsay D ^b   Clark, Matthew A ^b   Windsor, John A ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Acute respiratory distress syndrome; Lipid peroxidation; Myeloperoxidase; Oxidative stress; Protein carbonyl; Sepsis; Trauma

Indexed keywords

CARBONYL DERIVATIVE; LIPID; MYELOPEROXIDASE; PROTEIN DERIVATIVE; THIOBARBITURIC ACID;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CORRELATION FUNCTION; CRITICAL ILLNESS; ENZYME ACTIVITY; HUMAN; LEUKOCYTE ACTIVATION; LIPID OXIDATION; LUNG LAVAGE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEPSIS; TISSUE LEVEL;

EID: 0033961598     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200001000-00024     Document Type: Article

References (58)

1. 1. Manson NH, Hess ML: Interaction of oxygen free radicals and cardiac sarcoplasmic reticulum: Proposed role in the pathogenesis of endotoxic shock. Circ Shock 1983; 10: 205-213
2. 2. Zimmerman JJ: Defining the role of oxyradicals in the pathogenesis of sepsis. Crit Care Med 1995; 23:616-617
3. 3. Forni LG, Kelly FJ, Leach RM: Radical approach to the acute respiratory distress syndrome. Redox Rep 1997; 3:85-97
4. 4. Repine JE: Scientific perspectives on adult respiratory distress syndrome. Lancet 1992; 339:466-469
5. 5. Heffner JE, Repine JE: Pulmonary strategies of antioxidant defense. Am Rev Respir Dis 1989; 140:531-554
6. 6. McGuire WW, Spragg RG, Cohen AB, et al: Studies of the pathogenesis of the adult respiratory distress syndrome. J Clin Invest 1982; 69:543-553
7. 7. Cochrane CG, Spragg R, Revak SD: Pathogenesis of adult respiratory distress syndrome: Evidence of oxidant activity in bronchoalveolar lavage fluid. J Clin Invest 1983; 71:754-761
8. 8. Pacht ER, Timerman AP, Lykens MG, et al: Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome. Chest 1991; 100: 1397-1403
9. 9. Bunnell E, Pacht ER: Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis 1993; 148:1174-1178
10. 10. Baldwin SR, Simon RH, Grum CM, et al: Oxidant activity in expired breath of patients with adult respiratory distress syndrome. Lancet 1986; i:11-14
11. 11. Sznajder JI, Fraiman A, Hall JB, et al: Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure. Chest 1989; 96:606-612
12. 12. Richard C, Lemonnier F, Thibault M, et al: Vitamin E deficiency and lipoperoxidation during adult respiratory distress syndrome. Crit Care Med 1990; 18:4-9
13. 13. Goode HF, Cowley HC, Walker BE, et al: Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction. Crit Care Med 1995; 23:646-651
14. 14. Quinlan GJ, Evans TW, Gutteridge JMC: Linoleic acid and protein thiol changes suggestive of oxidative damage in the plasma of patients with adult respiratory distress syndrome. Free Radic Res 1994; 20:299-306
15. 15. Stites SW, Nelson ME, Wesselius LJ: Transferrin concentrations in serum and lower respiratory tract fluid of mechanically ventilated patients with COPD or ARDS. Chest 1995; 107:1681-1685
16. 16. Krsek-Staples JA, Kew RR, Webster RO: Ceruloplasmin and transferrin levels are altered in serum and bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Am Rev Respir Dis 1997; 145: 1009-1015
17. 17. Cowley HC, Bacon PJ, Goode HF, et al: Plasma antioxidant potential in severe sepsis: A comparison of survivors and nonsurvivors. Crit Care Med 1996; 24:1179-1183
18. 18. Galley HF, Howdle PD, Walker BE, et al: The effects of intravenous antioxidants in patients with septic shock. Free Radic Biol Med 1997; 23:768-774
19. 19. Takeda K, Shimada Y, Amano M, et al: Plasma lipid peroxides and alpha-tocopherol in critically ill patients. Crit Care Med 1984; 12:957-959
20. 20. Machiedo GW, Powell RJ, Rush BF Jr, et al: The incidence of decreased red blood cell deformability in sepsis and the association with oxygen free radical damage and multiple-system organ failure. Arch Surg 1989; 124:1386-1389
21. 21. Baouali AB, Aube H, Maupoil V, et al: Plasma lipid peroxidation in critically ill patients: Importance of mechanical ventilation. Free Radic Biol Med 1994; 16:223-227
22. 22. Roumen RM, Hendriks T, de Man BM, et al: Serum lipofuscin as a prognostic indicator of adult respiratory distress syndrome and multiple organ failure. Br J Surg 1994; 81: 1300-1305
23. 23. Quinlan GJ, Evans TW, Gutteridge JMC: 4-Hydroxy-2-nonenal levels increase in the plasma of patients with adult respiratory distress syndrome as linoleic acid appears to fall. Free Radic Res 1994; 21:95-106
24. 24. Keen RR, Stella L, Flanigan DP, et al: Differential detection of plasma hydroperoxides in sepsis. Crit Care Med 1991; 19:1114-1119
25. 25. Keen RR, Stella LA, Flanigan DP, et al: Differences between arterial and mixed venous levels of plasma hydroperoxides following major thoracic and abdominal operations. Free Radic Biol Med 1990; 9:485-494
26. 26. Draper HH, Hadley M: Malondialdehyde determination as an index of lipid peroxidation. Methods Enzymol 1990; 186:421-431
27. 27. Esterbauer H, Cheeseman KH: Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol 1990; 186:407-421
28. 28. Quinlan GJ, Evans TW, Gutteridge JMC: Oxidative damage to plasma proteins in adult respiratory distress syndrome. Free Radic Res 1994; 20:289-299
29. 29. Lloyd SS, Chang AK, Taylor FB Jr, et al: Free Radicals and septic shock in primates: The role of tumor necrosis factor. Free Radic Biol Med 1993; 14:233-242
30. 30. Demling RH, Lalonde C, Jin L-J, et al: Endotoxemia causes increased lung tissue lipid peroxidation in unanesthetized sheep. J Appl Physiol 1986; 161:2094-2100
31. 31. Sakaguchi S, Kanda N, Hsu CC, et al: Lipid peroxide formation and membrane damage in endotoxin-poisoned mice. Microbiol Immunol 1981; 25:229-244
32. 32. Ogawa R, Morita T, Kunimoto F, et al: Changes in hepatic lipoperoxide concentration in endotoxemic rats. Circ Shock 1982; 9:369-374
33. 33. Fagan JM, Ganguly M, Tiao G, et al: Sepsis increases oxidatively damaged proteins in skeletal muscle. Arch Surg 1996; 131: 1326-1332
34. 34. Downs TR, Dage RC, French JF: Reduction in endotoxin-induced organ dysfunction and cytokine secretion by a cyclic nitrone antioxidant. Int J Immunopharmacol 1995; 17: 571-580
35. 35. Powell RJ, Machiedo GW, Rush BF, et al: Effect of oxygen-free radical scavengers on survival in sepsis. Am Surg 1991; 57:86-88
36. 36. Kunimoto F, Morita T, Ogawa R, et al: Inhibition of lipid peroxidation improves survival rate of endotoxemic rats. Circ Shock 1987; 21:15-22
37. 37. Stadtman ER: Metal ion catalysed oxidation of proteins: Biochemical mechanism and biological consequences. Free Radic Biol Med 1990; 9:315-325
38. 38. Levine RL, Williams JA, Stadtman ER, et al: Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol 1994; 233:346-357
39. 39. Buss H, Chan TP, Sluis KB, et al: Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med 1997; 23: 361-366
40. 40. Young IS, Trimble ER: Measurement of malondialdehyde in plasma by high performance liquid chromatography with fluorometric detection. Ann Clin Biochem 1991; 28:504-508
41. 41. American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20:864-874
42. 42. Copes WS, Champion HR, Sacco WJ, et al: The Injury Severity Score revisited. J Trauma 1988; 28:69-77
43. 43. Knaus WA, Draper EA, Wagner DP: APACHE-II: A severity of disease classification system. Crit Care Med 1985; 13:818-824
44. 44. Rennard SI, Basset G, Lecossier D, et al: Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J Appl Physiol 1986; 60: 532-538
45. 45. Bozeman PM, Learn DB, Thomas EL: Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase. J Immunol Methods 1990; 126:125-133
46. 46. Lyras L, Evans PJ, Shaw PJ, et al: Oxidative damage and motor neurone disease difficulties in the measurement of protein carbonyls in human brain tissue. Free Radic Res 1996; 24:397-406
47. 47. Reznick AZ, Cross CE, Hu ML, et al: Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation. Biochem J 1992; 286:607-611
48. 48. Blakeman DP, Ryan TP, Jolly RA, et al: Diquat-dependent protein carbonyl formation: Identification of lipid-dependent and lipid-independent pathways. Biochem Pharmacol 1995; 50:929-935
49. 49. Ciolino HP, Levine RL: Modification of proteins in endothelial cell death during oxidative stress. Free Radic Biol Med 1997; 22: 1277-1282
50. 50. Vissers MCM, Winterbourn CC: The effect of oxidants on neutrophil-mediated degradation of basement membrane collagen. Biochim Biophys Acta 1986; 889:277-286
51. 51. Mitch WE, Goldberg AL: Mechanisms of muscle wasting: The role of the ubiquitin-proteasome pathway. N Engl J Med 1996; 335:1897-1905
52. 52. Damas P, Canivet J-L, De Groote D: Sepsis and serum cytokine concentrations. Crit Care Med 1997; 25:405-412
53. 53. Foex BA, Lamb WR, Roberts TE: Early cytokine response to multiple injury. Injury 1993; 24:373-376
54. 54. Weiss SJ: Tissue destruction by neutrophils. N Engl J Med 1989; 320:365-376
55. 55. Kettle AJ, Winterbourn CC: Myeloperoxidase: A key regulator of neutrophil oxidant production. Redox Rep 1997; 3:3-15
56. 56. Jepsen S, Hervlevsen P, Knudsen P, et al: Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: A prospective, randomized placebo-controlled study. Crit Care Med 1992; 20:918-923
57. 57. Clark MA, Plank LD, Connolly AB, et al: Effect of a chimeric antibody to tumor necrosis factor-α on cytokine and physiologic responses in patients with severe sepsis: A randomized clinical trial. Crit Care Med 1998; 26:1650-1659
58. 58. Boehrer H, Qiu F, Zimmerman T, et al: Role of NFkB in the mortality of sepsis. J Clin Invest 1997; 100:972-985