Inhibition of inducible nitric oxide synthase prevents LPS-induced acute lung injury in dogs

Journal of Immunology

Volumn 160, Issue 6, 1998, Pages 3031-3037

  Numata, Mari ^a   Suzuki, Shunsuke ^a   Miyazawa, Naoki ^a   Miyashita, Akira ^a   Nagashima, Yoji ^a   Inoue, Satoshi ^a   Kaneko, Takeshi ^a   Okubo, Takao ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; THIOUREA DERIVATIVE;

ACUTE DISEASE; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; ENZYME INHIBITION; LUNG DISEASE; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; DOGS; ENZYME INHIBITORS; GUANIDINES; HEMODYNAMIC PROCESSES; ISOTHIURONIUM; LIPOPOLYSACCHARIDES; LUNG; NEUTROPHILS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PULMONARY GAS EXCHANGE; RESPIRATORY DISTRESS SYNDROME, ADULT; TYROSINE;

EID: 0032520767     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Bernard, G. R., A. Artigas, K. L. Brigham, J. Carlet, K. Falke, L. Hudson, M. Lamy, J. R. Legall, A. Morris, R. Spragg, and Consensus Committee. 1994. The American-European consensus conference on ARDS. Am. J. Respir. Crit. Care Med. 149:818.
2. 1 in patients with the adult respiratory distress syndrome. Chest 96:114.
3. Natanson, C., W. D. Hoffman, A. F. Suffredini, P. Eichacker, and R. L. Danner. 1994. Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. Ann. Intern. Med. 120:771.
4. Bernard, G. R., J. M. Luce, C. L. Sprung, J. E. Rinaldo, R. M. Tate, W. J. Sibbald, K. Kariman, S. Higgins, R. Bradley, C. A. Metz, T. R. Harris, and K. L. Brigham. 1987. High-dose corticosteroids in patients with the adult respiratory distress syndrome. N. Engl. J. Med. 317:1565.
5. Palmer, R. M. J., D. S. Ashtibm, and S. Moncada. 1987. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333:664.
6. Moncada, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev. 43:109.
7. Lowenstein, C. J., J. L. Dinerman, and S. H. Snyder. 1994. Nitric oxide: a physiologic messenger. Ann. Intern. Med. 120:227.
8. Nathan, C., and Q. Xie. 1994. Nitric oxide synthases: roles, tolls, and controls. Cell 78:915.
9. Geller, D. A., A. K. Nussler, M. DiSilvio, C. J. Lowenstein, R. A. Shapiro, S. C. Wang, R. L. Simmons, and T. R. Billiar. 1993. Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc. Natl. Acad. Sci. USA 90:522.
10. Stuehr, D. J., and M. A. Marletta. 1987. Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines or interferon-γ. J. Immunol. 139:518.
11. Ischiropoulos, H., L. Zhu, and J. S. Beckman. 1992. Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298:446.
12. Beckman, J. S., H. Ischiropoulos, M. van der Woerd, C. Smith, J. Chen, J. Harrison, J. C. Martin, and M. Tsai. 1992. Kinetics of superoxide dismutase and iron catalyzed nitration of phenolics by peroxynitrite. Arch. Biochem. Biophys. 298:438.
13. Mulligan, M. S., J. M. Hevel, M. A. Marletta, and P. A. Ward. 1991. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc. Natl. Acad. Sci. USA 88:6338.
14. Beckman, J. S., M. Carson, C. D. Smith, and W. H. Koppenol. 1993. ALS, SOD and peroxynitrite. Nature 364:84.
15. Lipton, S. A., Y. B. Choi, Z. H. Pan, S. Z. Lei, H. S. V. Chen, N. J. Sucher, J. Loscalzo, D. J. Singel, and J. S. Stamler. 1993. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364:626.
16. G-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide. Proc. Natl. Acad. Sci. USA 87:3629.
17. G-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem. Biophys. Res. Commun. 172:1132.
18. Szabó, C., A. L. Salzman, and H. Ischiropoulos. 1995. Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo. FEBS Lett. 363:235.
19. Kooy, N. W., J. A. Royall, Y. Z. Ye, R. Kelly, and J. S. Beckman. 1995. Evidence for in vivo peroxynitrite production in human acute lung injury. Am. J. Respir. Crit. Care Med. 151:1250.
20. Haddad, I. Y., G. Pataki, P. Hu, C. Galliani, J. S. Beckman, and S. Matalon. 1994. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J. Clin. Invest. 94:2407.
21. Misko, T. P., W. M. Moore, T. P. Kasten, G. A. Nickols, J. A. Corbett, R. G. Tilton, M. L. McDaniel, J. R. Williamson, and M. G. Gurrie. 1993. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Phamacol. 233:119.
22. Griffith, M. J. D., M. Messent, R. J. MacAllister, and T. W. Evans. 1993. Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br. J. Pharmacol. 110:963.
23. Szabó, C., G. J. Southan, and C. Thiemermann. 1994. Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc. Natl. Acad. Sci. USA 91:12472.
24. Suzuki, S., T. Akahori, N. Miyazawa, M. Numata, T. Okubo, and J. P. Butler. 1996. Alveolar surface area-to-lung volume ratio in oleic acid-induced pulmonary edema. J. Appl. Physiol. 80:742.
25. Pearce, M. L., J. Yamashita, and J. Beazell. 1965. Measurement of pulmonary edema. Circ. Res. 16:482.
26. Kobzik, L. K., D. S. Bredt, C. J. Lowenstein, J. Drazen, B. Gaston, D. Sugarbaker, and J. S. Stamler. 1993. Nitric oxide synthase in human and rat lung: immuno-cytochemical and histochemical localization. Am. J. Respir. Cell Mol. Biol. 9:371.
27. Kaneko, T., P. R. Massion, M. Hara, and J. A. Nadel. 1996. Ragweed antigen causes interleukin-8 production in sensitized dog trachea. Am. J. Respir. Crit. Care Med. 153:136.
28. Jorens, P. G., J. B. Y. Richman-Eisenstat, B. P. Housset, P. D. Graf, I. F. Ueki, J. Olesch, and J. A. Nadel. 1992. Interleukin-8 induces neutrophil accumulation but not protease secretion in the canine trachea. Am. J. Physiol. 263:L708.
29. Beckman, J. S., Y. Z. Ye, P. G. Anderson, J. Chen, M. A. Accavitti, M. M. Tarpey, and C. R. White. 1994. Extensive nitration of protein tyrosine in human atherosclerosis detected by immunohistochemistry. Biol. Chem. Hoppe-Seyler 375:81.
30. Trelstad, R. L., W. M. Zapol, and E. G. Martin. 1985. Interstitial alterations following acute lung injury. In Acute Respiratory Failure. W. M. Zapol and K. J. Falke, eds. Marcel Dekker, New York, p. 185.
31. Glauser, M. P., G. Zanetti, J.-D. Baumgartner, and J. Cohen. 1991. Septic shock: pathogenesis. Lancet 338:732.
32. Cross, A. H., T. P. Misko, R. F. Lin, W. F. Hickey, J. L. Trotter, and R. G. Tilton. 1994. Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice. J. Clin. Invest. 93:2684.
33. Connor, J. R., P. T. Manning, S. L. Settle, W. M. Moore, G. M. Jerome, R. K. Webber, F. S. Tjoeng, and M. G. Currie. 1995. Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur. J. Pharmacol. 273:15.
34. G-monomethyl-L-arginine: a role for cyclic GMP. Blood 74:1885.
35. Haddad, I. Y., H. Ischiropoulos, B. A. Holm, J. S. Beckman, J. R. Baker, and S. Matalon. 1993. Mechanisms of peroxynitrite-induced injury to pulmonary surfactants. Am. J. Physiol. 265:1555.
36. Beauvais, F., L. Michel, and L. Dubertret. 1995. Exogenous nitric oxide elicits chemotaxis of neutrophils in vitro. J. Cell. Physiol. 165:610.
37. Cross, C. E., A. van der Vliet, C. A. O'Neill, and J. P. Eiserich. 1994. Reactive oxygen species and the lung. Lancet 344:930.
38. Berisha, H. I., H. Pakbaz, A. Absood, and S. I. Said. 1994. Nitric oxide as a mediator of oxidant lung injury due to paraquat. Proc. Natl. Acad. Sci. USA 91:7445.
39. Ischiropoulos, H., A. B. Al-Mehdi, and A. B. Fisher. 1995. Reactive species in ischemic rat lung injury: contribution of peroxynitrite. Am. J. Physiol. 269:L158.
40. Wizemann, T. M., C. R. Gardner, J. D. Laskin, S. Quinones, S. K. Durham, N. L. Goller, T. Ohnishi, and D. Laskin. 1994. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia. J. Leukocyte Biol. 56:759.
41. Natanson, C., P. W. Eichenholz, R. L. Danner, P. Eichacker, W. D. Hoffman, G. C. Kuo, S. M. Bank, T. J. MacVitie, and J. E. Parrillo. 1989. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock. J. Exp. Med. 169:823.
42. W-Amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin. J. Exp. Med. 176:1175.
43. Ruetten, H., and C. Thiemermann. 1996. Prevention of the expression of inducible nitric oxide synthase by aminoguanidine or aminoethyl-isothiourea in macrophages and in the rat. Biochem. Biophys. Res. Commun. 225:525.
44. Lewis, J. F., and A. H. Jobe. 1993. Surfactant and the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 147:218.