Comparison of S-adenosyl-l-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose

Toxicology

Volumn 244, Issue 1, 2008, Pages 25-34

  Terneus, Marcus V ^a   Brown, J Michael ^a   Carpenter, A Betts ^a   Valentovic, Monica A ^a  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetaminophen; Antidote; Hepatotoxicity; Mice; N acetylcysteine; S adenosylmethionine

Indexed keywords

4 HYDROXYNONENAL; ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; GLUTATHIONE; PARACETAMOL; S ADENOSYLMETHIONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG OVERDOSE; LIPID PEROXIDATION; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ACETAMINOPHEN; ACETYLCYSTEINE; ALANINE TRANSAMINASE; ALDEHYDES; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; GLUTATHIONE; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; LIVER; LIVER FAILURE, ACUTE; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, POLARIZATION; ORGAN SIZE; OVERDOSE; PROTEIN CARBONYLATION; S-ADENOSYLMETHIONINE; TIME FACTORS;

MUS;

EID: 37549052936     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.10.027     Document Type: Article

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