Transforming growth factor β suppresses osteoblast differentiation via the vimentin activating transcription factor 4 (ATF4) axis

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 35975-35984

  Lian, Na ^a,b   Lin, Tonghui ^a   Liu, Wenguang ^a   Wang, Weiguang ^a,b   Li, Ngzhen ^a   Sun, Stephanie ^a   Nyman, Jeffry S ^a,c   Yang, Xiangli ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Tennessee Valley Healthcare System   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ALKALINE PHOSPHATASE ACTIVITY; IN-VITRO; INTERMEDIATE FILAMENTS; LEUCINE ZIPPERS; NEGATIVE REGULATORS; OSTEOBLAST DIFFERENTIATION; OSTEOCALCIN; POST-TRANSCRIPTIONAL; SMAD SIGNALING; TRANSFORMING GROWTH FACTORS; UP-REGULATION; VIMENTIN; WILD-TYPE CELLS;

CHEMICAL ACTIVATION; MAMMALS; MONOCLONAL ANTIBODIES; PHOSPHATASES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

OSTEOBLASTS;

ACTIVATING TRANSCRIPTION FACTOR 4; ALKALINE PHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN; OSTEOCALCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MASS; CELL DIFFERENTIATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; MINERALIZATION; MOUSE; NEWBORN; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; TRANSACTIVATION; UPREGULATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; MICE; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCALCIN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; VIMENTIN;

EID: 84867800912     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.372458     Document Type: Article

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